Bone marrow transplantation prolongs life span and ameliorates neurologic manifestations in Sandhoff disease mice

Journal of Clinical Investigation

Volumn 101, Issue 9, 1998, Pages 1881-1888

  Norflus, Francine ^a   Tifft, Cynthia J ^a,b   McDonald, Michael P ^c   Goldstein, Gregory ^c   Crawley, Jacqueline N ^c   Hoffmann, Alexander ^d   Sandhoff, Konrad ^d   Suzuki, Kinuko ^e   Proia, Richard L ^a,c  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

^d UNIVERSITY OF BONN   (Germany)

^e UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

Beta N acetylhexosaminidase metabolism; Blood brain barrier; Disease models, animal; Gangliosidoses physiopathology; Tay Sachs disease metabolism

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BLOOD BRAIN BARRIER; BONE MARROW TRANSPLANTATION; LIFESPAN; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; SANDHOFF DISEASE; TREATMENT OUTCOME;

EID: 0032080858     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI2127     Document Type: Article

References (28)

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