Microglial activation precedes acute neurodegeneration in Sandhoff disease and is suppressed by bone marrow transplantation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 97, Issue 20, 2000, Pages 10954-10959

  Wada, Ryuichi ^a   Tifft, Cynthia J ^a,b   Proia, Richard L ^a,c  

^a NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^b CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^c NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Apoptosis; cDNA microarray; Macrophage; Microglia; Tumor necrosis factor

Indexed keywords

BETA N ACETYLHEXOSAMINIDASE; COMPLEMENTARY DNA; GANGLIOSIDE GM2; GLYCOLIPID;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BONE MARROW TRANSPLANTATION; BRAIN REGION; CASE REPORT; CELL ACTIVATION; CHILD; CONTROLLED STUDY; EXPRESSED SEQUENCE TAG; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; INFLAMMATION; LYSOSOME STORAGE DISEASE; MACROPHAGE ACTIVATION; MICROGLIA; MOUSE; NERVE CELL NECROSIS; NERVE DEGENERATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENESIS; PRION DISEASE; PRIORITY JOURNAL; SANDHOFF DISEASE; TREATMENT OUTCOME; UNINDEXED SEQUENCE;

EID: 0034718598     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.97.20.10954     Document Type: Article

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