메뉴 건너뛰기




Volumn 162, Issue 6, 1999, Pages 3176-3187

The Jun kinase cascade is responsible for activating the CD28 response element of the IL-2 promoter: Proof of cross-talk with the IκB kinase cascade

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 2; PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE;

EID: 0033559545     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (41)

References (54)
  • 3
    • 0026537347 scopus 로고
    • CD28-mediated signaling co-stimulates murine T cells and prevents induction of anergy in T-cell clones
    • Harding, F. A., J. G. McArthur, J. A. Gross, D. H. Raulet, and J. P. Allison. 1992. CD28-mediated signaling co-stimulates murine T cells and prevents induction of anergy in T-cell clones. Nature 356:607.
    • (1992) Nature , vol.356 , pp. 607
    • Harding, F.A.1    McArthur, J.G.2    Gross, J.A.3    Raulet, D.H.4    Allison, J.P.5
  • 5
    • 0026061865 scopus 로고
    • Regulation of interleukin-2 gene enhancer activity by the T-cell accessory molecule CD28
    • Fraser, J. D., B. A. Irving, G. R. Crabtree, and A. Weiss. 1991. Regulation of interleukin-2 gene enhancer activity by the T-cell accessory molecule CD28. Science 251:313.
    • (1991) Science , vol.251 , pp. 313
    • Fraser, J.D.1    Irving, B.A.2    Crabtree, G.R.3    Weiss, A.4
  • 6
    • 0029041568 scopus 로고
    • Transcriptional regulation of the IL-2 gene
    • Jain, J., C. Loh, and A. Rao. 1995. Transcriptional regulation of the IL-2 gene. Curr. Opin. Immunol. 7:333.
    • (1995) Curr. Opin. Immunol. , vol.7 , pp. 333
    • Jain, J.1    Loh, C.2    Rao, A.3
  • 9
    • 0028329603 scopus 로고
    • Interleukin-2 transcription is regulated in vivo at the level of coordinated binding of both constitutive and regulated factors
    • Garrity, P. A., D. Chen, E. V. Rothenberg, and B. J. Wold. 1994. Interleukin-2 transcription is regulated in vivo at the level of coordinated binding of both constitutive and regulated factors. Mol. Cell. Biol. 14:2159.
    • (1994) Mol. Cell. Biol. , vol.14 , pp. 2159
    • Garrity, P.A.1    Chen, D.2    Rothenberg, E.V.3    Wold, B.J.4
  • 10
    • 0028014460 scopus 로고
    • Signal transduction by lymphocyte antigen receptors
    • Weiss, A., and D. R. Littman. 1994. Signal transduction by lymphocyte antigen receptors. Cell 76:263.
    • (1994) Cell , vol.76 , pp. 263
    • Weiss, A.1    Littman, D.R.2
  • 11
    • 0026702322 scopus 로고
    • Regulation of T-cell lymphokine gene transcription by the accessory molecule CD28
    • Fraser, J. D., and A. Weiss. 1992. Regulation of T-cell lymphokine gene transcription by the accessory molecule CD28. Mol. Cell. Biol. 12:4357.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 4357
    • Fraser, J.D.1    Weiss, A.2
  • 12
    • 0031001510 scopus 로고    scopus 로고
    • CD28 mediates transcriptional upregulation of the interleukin-2 (IL-2) promoter through a composite element containing the CD28RE and NF-IL-2B AP-1 sites
    • Shapiro, V. S., K. E. Truitt, J. B. Imboden, and A. Weiss. 1997. CD28 mediates transcriptional upregulation of the interleukin-2 (IL-2) promoter through a composite element containing the CD28RE and NF-IL-2B AP-1 sites. Mol. Cell. Biol. 17:4051.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 4051
    • Shapiro, V.S.1    Truitt, K.E.2    Imboden, J.B.3    Weiss, A.4
  • 13
    • 0031204429 scopus 로고    scopus 로고
    • Involvement of Rel, Fos, and Jun proteins in binding activity to the IL-2 promoter CD28 response element/AP-1 sequence in human T cells
    • McGuire, K. L., and M. Iacobelli. 1997. Involvement of Rel, Fos, and Jun proteins in binding activity to the IL-2 promoter CD28 response element/AP-1 sequence in human T cells. J. Immunol. 159:1319.
    • (1997) J. Immunol. , vol.159 , pp. 1319
    • McGuire, K.L.1    Iacobelli, M.2
  • 14
    • 0030176384 scopus 로고    scopus 로고
    • Upstream-downstream: CD28 cosignaling pathways and T cell function
    • Rudd, C. E. 1996. Upstream-downstream: CD28 cosignaling pathways and T cell function. Immunity 4:527.
    • (1996) Immunity , vol.4 , pp. 527
    • Rudd, C.E.1
  • 15
    • 0028221022 scopus 로고
    • T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif
    • Prasad, K. V., Y. C. Cai, M. Raab, B. Duckworth, L. Cantley, S. E. Shoelson, and C. E. Rudd. 1994. T-cell antigen CD28 interacts with the lipid kinase phosphatidylinositol 3-kinase by a cytoplasmic Tyr(P)-Met-Xaa-Met motif. Proc. Natl. Acad. Sci. USA 91:2834.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 2834
    • Prasad, K.V.1    Cai, Y.C.2    Raab, M.3    Duckworth, B.4    Cantley, L.5    Shoelson, S.E.6    Rudd, C.E.7
  • 16
    • 0028972712 scopus 로고
    • CD28-mediated costimulation in the absence of phosphatidylinositol 3-kinase association and activation
    • Crooks, M. E., D. R. Littman, R. H. Carter, D. T. Fearon, A. Weiss, and P. H. Stein. 1995. CD28-mediated costimulation in the absence of phosphatidylinositol 3-kinase association and activation. Mol. Cell. Biol. 15:6820.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 6820
    • Crooks, M.E.1    Littman, D.R.2    Carter, R.H.3    Fearon, D.T.4    Weiss, A.5    Stein, P.H.6
  • 18
    • 0029861909 scopus 로고    scopus 로고
    • Regulation of interleukin-2 transcription by inducible stable expression of dominant negative and dominant active mitogen-activated protein kinase kinase kinase in Jurkat T cells: Evidence for the importance of Ras in a pathway that is controlled by dual receptor stimulation
    • Faris, M. N. Kokot, L. Lee, and A. E. Nel. 1996. Regulation of interleukin-2 transcription by inducible stable expression of dominant negative and dominant active mitogen-activated protein kinase kinase kinase in Jurkat T cells: evidence for the importance of Ras in a pathway that is controlled by dual receptor stimulation. J. Biol. Chem. 271:27366.
    • (1996) J. Biol. Chem. , vol.271 , pp. 27366
    • Faris, M.1    Kokot, N.2    Lee, L.3    Nel, A.E.4
  • 19
    • 0028291525 scopus 로고
    • JNK is involved in signal integration during costimulation of T lymphocytes
    • Su, B., E. Jacinto, M. Hibi, T. Kallunki, M. Karin, and Y. Ben-Neriah. 1994. JNK is involved in signal integration during costimulation of T lymphocytes. Cell 77:727.
    • (1994) Cell , vol.77 , pp. 727
    • Su, B.1    Jacinto, E.2    Hibi, M.3    Kallunki, T.4    Karin, M.5    Ben-Neriah, Y.6
  • 20
    • 0028030884 scopus 로고
    • Dominant negative mutant of c-Jun inhibits NF-AT transcriptional activity and prevents IL-2 gene transcription
    • Petrak, D., S. A. Memon, M. J. Birrer, J. D. Ashwell, and C. M. Zacharchuk. 1994. Dominant negative mutant of c-Jun inhibits NF-AT transcriptional activity and prevents IL-2 gene transcription. J. Immunol. 153:2046.
    • (1994) J. Immunol. , vol.153 , pp. 2046
    • Petrak, D.1    Memon, S.A.2    Birrer, M.J.3    Ashwell, J.D.4    Zacharchuk, C.M.5
  • 22
    • 0030613758 scopus 로고    scopus 로고
    • NF-κB activation: The IκB kinase revealed?
    • Stancovski, I., and D. Baltimore. 1997. NF-κB activation: the IκB kinase revealed? Cell 91:299.
    • (1997) Cell , vol.91 , pp. 299
    • Stancovski, I.1    Baltimore, D.2
  • 23
    • 0030613551 scopus 로고    scopus 로고
    • The IκB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation
    • Zandi, E., D. M. Rothwarf, M. Delhase, M. Hayakawa, and M. Karin. 1997. The IκB kinase complex (IKK) contains two kinase subunits, IKKα and IKKβ, necessary for IκB phosphorylation and NF-κB activation. Cell 91:243.
    • (1997) Cell , vol.91 , pp. 243
    • Zandi, E.1    Rothwarf, D.M.2    Delhase, M.3    Hayakawa, M.4    Karin, M.5
  • 24
    • 0027207242 scopus 로고
    • Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of IκBα: A mechanism for NF-κB activation
    • Beg, A. A., T. S. Finco, P. V. Nantermet, and A. S. Baldwin, Jr. 1993. Tumor necrosis factor and interleukin-1 lead to phosphorylation and loss of IκBα: a mechanism for NF-κB activation. Mol. Cell. Biol. 13:3301.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 3301
    • Beg, A.A.1    Finco, T.S.2    Nantermet, P.V.3    Baldwin A.S., Jr.4
  • 25
    • 0028978032 scopus 로고
    • Phosphorylation of human IκB-α on serines 32 and 36 controls IκB-α proteolysis and NF-κB activation in response to diverse stimuli
    • Traenckner, E. B., H. L. Pahl, T. Henkel, K. N. Schmidt, S. Wilk, and P. A. Baeuerle. 1995. Phosphorylation of human IκB-α on serines 32 and 36 controls IκB-α proteolysis and NF-κB activation in response to diverse stimuli. EMBO J. 14:2876.
    • (1995) EMBO J. , vol.14 , pp. 2876
    • Traenckner, E.B.1    Pahl, H.L.2    Henkel, T.3    Schmidt, K.N.4    Wilk, S.5    Baeuerle, P.A.6
  • 26
    • 0031285250 scopus 로고    scopus 로고
    • Activation of the IκBα kinase complex by MEKK1, a kinase of the JNK pathway
    • Lee, F. S., J. Hagler, Z. J. Chen, and T. Maniatis. 1997. Activation of the IκBα kinase complex by MEKK1, a kinase of the JNK pathway. Cell 88:213.
    • (1997) Cell , vol.88 , pp. 213
    • Lee, F.S.1    Hagler, J.2    Chen, Z.J.3    Maniatis, T.4
  • 28
    • 0032583949 scopus 로고    scopus 로고
    • Differential regulation of IκB kinase α and β by two upstream kinases. NF-κB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1
    • Nakano, H., M. Shindo, S. Sakon, S. Nishinaka, M. Mihara, H. Yagita, and K. Okumura. 1998. Differential regulation of IκB kinase α and β by two upstream kinases. NF-κB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1. Proc. Natl. Acad. Sci. USA 95:3537.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 3537
    • Nakano, H.1    Shindo, M.2    Sakon, S.3    Nishinaka, S.4    Mihara, M.5    Yagita, H.6    Okumura, K.7
  • 33
    • 0031813436 scopus 로고    scopus 로고
    • Stress-induced Fas ligand expression in T cells is mediated through a MEK kinase 1-regulated response element in the Fas ligand promoter
    • Faris, M., K. M. Latinis, S. J. Kempiak, G. A. Koretzky, and A. Nel. 1998. Stress-induced Fas ligand expression in T cells is mediated through a MEK kinase 1-regulated response element in the Fas ligand promoter. Mol. Cell. Biol. 18:5414.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 5414
    • Faris, M.1    Latinis, K.M.2    Kempiak, S.J.3    Koretzky, G.A.4    Nel, A.5
  • 34
    • 0029670085 scopus 로고    scopus 로고
    • Phosphorylation of IκBα in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability
    • Lin, R., P. Beauparlant, C. Makris, S. Meloche, and J. Hiscott. 1996. Phosphorylation of IκBα in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability. Mol. Cell. Biol. 16:1401.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1401
    • Lin, R.1    Beauparlant, P.2    Makris, C.3    Meloche, S.4    Hiscott, J.5
  • 35
    • 0030610362 scopus 로고    scopus 로고
    • A cytokine-responsive IκB kinase that activates the transcription factor NF-κB
    • DiDonato, J. A., M. Hayakawa, D. M. Rothwarf, E. Zandi, and M. Karin. 1997. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB. Nature 388:548.
    • (1997) Nature , vol.388 , pp. 548
    • Didonato, J.A.1    Hayakawa, M.2    Rothwarf, D.M.3    Zandi, E.4    Karin, M.5
  • 36
    • 0028302767 scopus 로고
    • The T-cell antigen receptor utilizes Lck, Raf-1, and MEK-1 for activating mitogen-activated protein kinase: Evidence for the existence of a second protein kinase C-dependent pathway in an Lck-negative Jurkat cell mutant
    • Gupta, S., A. Weiss, G. Kumar, S. Wang, and A. Nel. 1994. The T-cell antigen receptor utilizes Lck, Raf-1, and MEK-1 for activating mitogen-activated protein kinase: evidence for the existence of a second protein kinase C-dependent pathway in an Lck-negative Jurkat cell mutant. J Biol. Chem. 269:17349.
    • (1994) J Biol. Chem. , vol.269 , pp. 17349
    • Gupta, S.1    Weiss, A.2    Kumar, G.3    Wang, S.4    Nel, A.5
  • 38
    • 0030067653 scopus 로고    scopus 로고
    • MEK1 and the extracellular signal-regulated kinases are required for the stimulation of IL-2 gene transcription in T cells
    • Whitehurst, C. E., and T. D. Geppert 1996. MEK1 and the extracellular signal-regulated kinases are required for the stimulation of IL-2 gene transcription in T cells. J. Immunol. 156:1020.
    • (1996) J. Immunol. , vol.156 , pp. 1020
    • Whitehurst, C.E.1    Geppert, T.D.2
  • 39
    • 0029670083 scopus 로고    scopus 로고
    • Mapping of the inducible IκB phosphorylation sites that signal its ubiquitination and degradation
    • DiDonato, J., F. Mercurio, C. Rosette, J. Wu-Li, H. Suyang, S. Ghosh, and M. Karin. 1996. Mapping of the inducible IκB phosphorylation sites that signal its ubiquitination and degradation. Mol. Cell. Biol. 16:1295.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1295
    • DiDonato, J.1    Mercurio, F.2    Rosette, C.3    Wu-Li, J.4    Suyang, H.5    Ghosh, S.6    Karin, M.7
  • 40
    • 0032900164 scopus 로고    scopus 로고
    • Activation of the human RANTES gene promoter in macrophage cell line by lipopolysaccharide is dependent on stress-activated protein kinases and the IκB kinase cascade: Implications for exacerbation of allergic inflammation by environmental pollutants
    • In press
    • Hiura, T., S. Kempiak, and A. Nel. 1999. Activation of the human RANTES gene promoter in macrophage cell line by lipopolysaccharide is dependent on stress-activated protein kinases and the IκB kinase cascade: implications for exacerbation of allergic inflammation by environmental pollutants. Clin. Immunol. In press.
    • (1999) Clin. Immunol.
    • Hiura, T.1    Kempiak, S.2    Nel, A.3
  • 41
    • 0029035315 scopus 로고
    • Sphingomyelin-ceramide turnover in CD28 costimulatory signaling
    • Chan, G., and A. Ochi. 1995. Sphingomyelin-ceramide turnover in CD28 costimulatory signaling. Eur. J. Immunol. 25:1999.
    • (1995) Eur. J. Immunol. , vol.25 , pp. 1999
    • Chan, G.1    Ochi, A.2
  • 42
    • 0032080604 scopus 로고    scopus 로고
    • Activation of p21-CDC42/ Rac-activated kinases by CD28 signaling: P21-activated kinase (PAK) and MEK kinase 1 (MEKK1) may mediate the interplay between CD3 and CD28 signals
    • Kaga, S., S. Ragg, K. A. Rogers, and A. Ochi. 1998. Activation of p21-CDC42/ Rac-activated kinases by CD28 signaling: p21-activated kinase (PAK) and MEK kinase 1 (MEKK1) may mediate the interplay between CD3 and CD28 signals. J. Immunol. 160:4182.
    • (1998) J. Immunol. , vol.160 , pp. 4182
    • Kaga, S.1    Ragg, S.2    Rogers, K.A.3    Ochi, A.4
  • 43
    • 0028329953 scopus 로고
    • JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain
    • Derijard, B., M. Hibi, I. H. Wu, T. Barrett, B. Su, T. Deng, M. Karin, and R. J. Davis. 1994. JNK1: a protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain. Cell 76:1025.
    • (1994) Cell , vol.76 , pp. 1025
    • Derijard, B.1    Hibi, M.2    Wu, I.H.3    Barrett, T.4    Su, B.5    Deng, T.6    Karin, M.7    Davis, R.J.8
  • 44
    • 0028609314 scopus 로고
    • Altering the specificity of signal transduction cascades: Positive regulation of c-Jun transcriptional activity by protein kinase A
    • Smeal, T., M. Hibi, and M. Karin. 1994. Altering the specificity of signal transduction cascades: positive regulation of c-Jun transcriptional activity by protein kinase A. EMBO J. 13:6006.
    • (1994) EMBO J. , vol.13 , pp. 6006
    • Smeal, T.1    Hibi, M.2    Karin, M.3
  • 45
    • 0030703604 scopus 로고    scopus 로고
    • Regulation and function of the JNK subgroup of MAP kinases
    • Minden, A., and M. Karin. 1997. Regulation and function of the JNK subgroup of MAP kinases. Biochim. Biophys. Acta 1333:F85.
    • (1997) Biochim. Biophys. Acta , vol.1333
    • Minden, A.1    Karin, M.2
  • 47
    • 0032546972 scopus 로고    scopus 로고
    • Stabilization of interleukin-2 mRNA by the c-Jun NH2-terminal kinase pathway
    • Chen, C. Y., F. Del Gatto-Konczak, Z. Wu, and M. Karin. 1998. Stabilization of interleukin-2 mRNA by the c-Jun NH2-terminal kinase pathway. Science 280: 1945.
    • (1998) Science , vol.280 , pp. 1945
    • Chen, C.Y.1    Gatto-Konczak, F.D.2    Wu, Z.3    Karin, M.4
  • 48
    • 0031909355 scopus 로고    scopus 로고
    • Cooperation between Syk and Rac1 leads to synergistic JNK activation in T lymphocytes
    • Jacinto, E., G. Werlen, and M. Karin. 1998. Cooperation between Syk and Rac1 leads to synergistic JNK activation in T lymphocytes. Immunity 8:31.
    • (1998) Immunity , vol.8 , pp. 31
    • Jacinto, E.1    Werlen, G.2    Karin, M.3
  • 49
    • 0032521266 scopus 로고    scopus 로고
    • Inhibition of T cell activation by pharmacologic disruption of the MEK1/ERK MAP kinase or calcineurin signaling pathways results in differential modulation of cytokine production
    • Dumont, F. J., M. J. Staruch, P. Fischer, C. DaSilva, and R. Camacho. 1998. Inhibition of T cell activation by pharmacologic disruption of the MEK1/ERK MAP kinase or calcineurin signaling pathways results in differential modulation of cytokine production. J. Immunol. 160:2579.
    • (1998) J. Immunol. , vol.160 , pp. 2579
    • Dumont, F.J.1    Staruch, M.J.2    Fischer, P.3    Dasilva, C.4    Camacho, R.5
  • 51
    • 0032080849 scopus 로고    scopus 로고
    • Inhibition of mitogen-activated protein kinase kinase blocks T cell proliferation but does not induce or prevent anergy
    • DeSilva, D. R., E. A. Jones, M. F. Favata, B. D. Jaffee, R. L. Magolda, J. M. Trzaskos, and P. A. Scherle. 1998. Inhibition of mitogen-activated protein kinase kinase blocks T cell proliferation but does not induce or prevent anergy. J. Immunol. 160:4175.
    • (1998) J. Immunol. , vol.160 , pp. 4175
    • DeSilva, D.R.1    Jones, E.A.2    Favata, M.F.3    Jaffee, B.D.4    Magolda, R.L.5    Trzaskos, J.M.6    Scherle, P.A.7
  • 53
    • 0031883140 scopus 로고    scopus 로고
    • The c-Jun N-terminal kinase cascade plays a role in stress-induced apoptosis in Jurkat cells by up-regulating Fas ligand expression
    • Faris, M., N. Kokot, K. M. Latinis, S. Kasibhatla, D. R. Green, G. A. Koretzky, and A. Nel. 1998. The c-Jun N-terminal kinase cascade plays a role in stress-induced apoptosis in Jurkat cells by up-regulating Fas ligand expression. J. Immunol. 160:134.
    • (1998) J. Immunol. , vol.160 , pp. 134
    • Faris, M.1    Kokot, N.2    Latinis, K.M.3    Kasibhatla, S.4    Green, D.R.5    Koretzky, G.A.6    Nel, A.7
  • 54
    • 0029753773 scopus 로고    scopus 로고
    • The role of c-Jun N-terminal kinase cascade (JNK) in apoptosis induced by ultraviolet C and gamma radiation: Duration of JNK activation may determine cell death and proliferation
    • Chen, Y. R., W. Wang, D. Templeton, R. J. Davis, and T.-H. Tan. 1996. The role of c-Jun N-terminal kinase cascade (JNK) in apoptosis induced by ultraviolet C and gamma radiation: duration of JNK activation may determine cell death and proliferation. J. Biol. Chem. 271:31929.
    • (1996) J. Biol. Chem. , vol.271 , pp. 31929
    • Chen, Y.R.1    Wang, W.2    Templeton, D.3    Davis, R.J.4    Tan, T.-H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.