T-bet-deficient NOD mice are protected from diabetes due to defects in both T cell and innate immune system function

Journal of Immunology

Volumn 183, Issue 1, 2009, Pages 75-82

  Esensten, Jonathan H ^a   Lee, Michael R ^a   Glimcher, Laurie H ^b   Bluestone, Jeffrey A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 12P40; TRANSCRIPTION FACTOR T BET; LYMPHOCYTE ANTIGEN RECEPTOR; T BOX TRANSCRIPTION FACTOR; T BOX TRANSCRIPTION FACTOR TBX21; T-BOX TRANSCRIPTION FACTOR TBX21;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CD4+ T LYMPHOCYTE; CELL COUNT; CONTROLLED STUDY; DIABETES MELLITUS; EFFECTOR CELL; GENE DELETION; IMMUNE RESPONSE; IMMUNE SYSTEM; IN VITRO STUDY; INCIDENCE; INNATE IMMUNITY; INSULITIS; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; NONOBESE DIABETIC MOUSE; PANCREAS; POLARIZATION; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; T LYMPHOCYTE; TH1 CELL; TRANSGENIC MOUSE; ANIMAL; C57BL MOUSE; CELL CULTURE; FEMALE; GENETICS; IMMUNOLOGY; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE ACTIVATION; METABOLISM; METHODOLOGY; MOUSE MUTANT; PANCREAS ISLET; PATHOLOGY; PHYSIOLOGY; TRANSPLANTATION;

ADOPTIVE TRANSFER; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; DIABETES MELLITUS, TYPE 1; FEMALE; IMMUNITY, INNATE; ISLETS OF LANGERHANS; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MICE, INBRED NOD; MICE, KNOCKOUT; MICE, TRANSGENIC; RECEPTORS, ANTIGEN, T-CELL; T-BOX DOMAIN PROTEINS; T-LYMPHOCYTES, REGULATORY; TH1 CELLS;

EID: 68949102074     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.0804154     Document Type: Article

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