-
1
-
-
0035856980
-
Biochemistry and molecular cell biology of diabetic complications
-
Brownlee M, (2001) Biochemistry and molecular cell biology of diabetic complications. Nature 414: 813-820.
-
(2001)
Nature
, vol.414
, pp. 813-820
-
-
Brownlee, M.1
-
2
-
-
79959600649
-
Acute hypoglycemia induces retinal cell death in mouse
-
Emery M, Schorderet D, Roduit R, (2011) Acute hypoglycemia induces retinal cell death in mouse. PLoS One 6: e21586.
-
(2011)
PLoS One
, vol.6
-
-
Emery, M.1
Schorderet, D.2
Roduit, R.3
-
3
-
-
0034800276
-
Hypoglycemia induces general neuronal death, whereas hypoxia and glutamate transport blockade lead to selective retinal ganglion cell death in vitro
-
Luo X, Lambrou G, Sahel J, Hicks D, (2001) Hypoglycemia induces general neuronal death, whereas hypoxia and glutamate transport blockade lead to selective retinal ganglion cell death in vitro. Invest Ophthalmol Vis Sci 42: 2695-2705.
-
(2001)
Invest Ophthalmol Vis Sci
, vol.42
, pp. 2695-2705
-
-
Luo, X.1
Lambrou, G.2
Sahel, J.3
Hicks, D.4
-
4
-
-
0033840949
-
Lactate prevents the alterations in tissue amino acids, decline in ATP, and cell damage due to aglycemia in retina
-
Zeevalk G, Nicklas W, (2000) Lactate prevents the alterations in tissue amino acids, decline in ATP, and cell damage due to aglycemia in retina. J Neurochem 75: 1027-1034.
-
(2000)
J Neurochem
, vol.75
, pp. 1027-1034
-
-
Zeevalk, G.1
Nicklas, W.2
-
5
-
-
33845913255
-
Hypoglycemia leads to age-related loss of vision
-
Umino Y, Everhart D, Solessio E, Cusato K, Pan J, et al. (2006) Hypoglycemia leads to age-related loss of vision. Proc Natl Acad Sci U S A 103: 19541-19545.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 19541-19545
-
-
Umino, Y.1
Everhart, D.2
Solessio, E.3
Cusato, K.4
Pan, J.5
-
6
-
-
58149141478
-
Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosa
-
Punzo C, Kornacker K, Cepko C, (2009) Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosa. Nat Neurosci 12: 44-52.
-
(2009)
Nat Neurosci
, vol.12
, pp. 44-52
-
-
Punzo, C.1
Kornacker, K.2
Cepko, C.3
-
7
-
-
79960912977
-
Acute hypoglycemia decreases central retinal function in the human eye
-
Khan M, Barlow R, Weinstock R, (2011) Acute hypoglycemia decreases central retinal function in the human eye. Vision Res 51: 1623-1626.
-
(2011)
Vision Res
, vol.51
, pp. 1623-1626
-
-
Khan, M.1
Barlow, R.2
Weinstock, R.3
-
8
-
-
0242351062
-
The Bcl-2-regulated apoptotic pathway
-
Willis S, Day C, Hinds M, Huang D, (2003) The Bcl-2-regulated apoptotic pathway. J Cell Sci 116: 4053-4056.
-
(2003)
J Cell Sci
, vol.116
, pp. 4053-4056
-
-
Willis, S.1
Day, C.2
Hinds, M.3
Huang, D.4
-
9
-
-
0037213368
-
The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions
-
Borner C, (2003) The Bcl-2 protein family: sensors and checkpoints for life-or-death decisions. Mol Immunol 39: 615-647.
-
(2003)
Mol Immunol
, vol.39
, pp. 615-647
-
-
Borner, C.1
-
10
-
-
0036716281
-
The Bcl2 family: regulators of the cellular life-or-death switch
-
Cory S, Adams J, (2002) The Bcl2 family: regulators of the cellular life-or-death switch. Nat Rev Cancer 2: 647-656.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 647-656
-
-
Cory, S.1
Adams, J.2
-
11
-
-
47249164452
-
The autophagic machinery is necessary for removal of cell corpses from the developing retinal neuroepithelium
-
Mellèn M, de la Rosa E, Boya P, (2008) The autophagic machinery is necessary for removal of cell corpses from the developing retinal neuroepithelium. Cell Death Differ 15: 1279-1290.
-
(2008)
Cell Death Differ
, vol.15
, pp. 1279-1290
-
-
Mellèn, M.1
de la Rosa, E.2
Boya, P.3
-
12
-
-
0032846377
-
Photoreceptor autophagy: effects of light history on number and opsin content of degradative vacuoles
-
Remé C, Wolfrum U, Imsand C, Hafezi F, Williams T, (1999) Photoreceptor autophagy: effects of light history on number and opsin content of degradative vacuoles. Invest Ophthalmol Vis Sci 40: 2398-2404.
-
(1999)
Invest Ophthalmol Vis Sci
, vol.40
, pp. 2398-2404
-
-
Remé, C.1
Wolfrum, U.2
Imsand, C.3
Hafezi, F.4
Williams, T.5
-
13
-
-
34548068863
-
Apoptosis and autophagy in photoreceptors exposed to oxidative stress
-
Kunchithapautham K, Rohrer B, (2007) Apoptosis and autophagy in photoreceptors exposed to oxidative stress. Autophagy 3: 433-441.
-
(2007)
Autophagy
, vol.3
, pp. 433-441
-
-
Kunchithapautham, K.1
Rohrer, B.2
-
14
-
-
1842583789
-
Development by self-digestion: molecular mechanisms and biological functions of autophagy
-
Levine B, Klionsky D, (2004) Development by self-digestion: molecular mechanisms and biological functions of autophagy. Dev Cell 6: 463-477.
-
(2004)
Dev Cell
, vol.6
, pp. 463-477
-
-
Levine, B.1
Klionsky, D.2
-
15
-
-
66449114033
-
p62 at the crossroads of autophagy, apoptosis, and cancer
-
Moscat J, Diaz-Meco M, (2009) p62 at the crossroads of autophagy, apoptosis, and cancer. Cell 137: 1001-1004.
-
(2009)
Cell
, vol.137
, pp. 1001-1004
-
-
Moscat, J.1
Diaz-Meco, M.2
-
16
-
-
77649242989
-
p62, an autophagy hero or culprit?
-
Rusten T, Stenmark H, (2010) p62, an autophagy hero or culprit? Nature cell biology 12: 207-209.
-
(2010)
Nature Cell Biology
, vol.12
, pp. 207-209
-
-
Rusten, T.1
Stenmark, H.2
-
17
-
-
66449099090
-
Autophagy suppresses tumorigenesis through elimination of p62
-
Mathew R, Karp C, Beaudoin B, Vuong N, Chen G, et al. (2009) Autophagy suppresses tumorigenesis through elimination of p62. Cell 137: 1062-1075.
-
(2009)
Cell
, vol.137
, pp. 1062-1075
-
-
Mathew, R.1
Karp, C.2
Beaudoin, B.3
Vuong, N.4
Chen, G.5
-
18
-
-
34548188741
-
Self-eating and self-killing: crosstalk between autophagy and apoptosis
-
Maiuri M, Zalckvar E, Kimchi A, Kroemer G, (2007) Self-eating and self-killing: crosstalk between autophagy and apoptosis. Nat Rev Mol Cell Biol 8: 741-752.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 741-752
-
-
Maiuri, M.1
Zalckvar, E.2
Kimchi, A.3
Kroemer, G.4
-
19
-
-
67549142261
-
Life and death partners: apoptosis, autophagy and the cross-talk between them
-
Eisenberg-Lerner A, Bialik S, Simon HU, Kimchi A, (2009) Life and death partners: apoptosis, autophagy and the cross-talk between them. Cell death and differentiation 16: 966-975.
-
(2009)
Cell Death and Differentiation
, vol.16
, pp. 966-975
-
-
Eisenberg-Lerner, A.1
Bialik, S.2
Simon, H.U.3
Kimchi, A.4
-
20
-
-
77950501014
-
mTOR regulation of autophagy
-
Jung C, Ro S, Cao J, Otto N, Kim D, (2010) mTOR regulation of autophagy. FEBS Lett 584: 1287-1295.
-
(2010)
FEBS Lett
, vol.584
, pp. 1287-1295
-
-
Jung, C.1
Ro, S.2
Cao, J.3
Otto, N.4
Kim, D.5
-
21
-
-
42949139481
-
AMPK phosphorylation of raptor mediates a metabolic checkpoint
-
Gwinn D, Shackelford D, Egan D, Mihaylova M, Mery A, et al. (2008) AMPK phosphorylation of raptor mediates a metabolic checkpoint. Mol Cell 30: 214-226.
-
(2008)
Mol Cell
, vol.30
, pp. 214-226
-
-
Gwinn, D.1
Shackelford, D.2
Egan, D.3
Mihaylova, M.4
Mery, A.5
-
22
-
-
79952227187
-
2-Deoxy-D-glucose treatment of endothelial cells induces autophagy by reactive oxygen species-mediated activation of the AMP-activated protein kinase
-
Wang Q, Liang B, Shirwany N, Zou M, (2011) 2-Deoxy-D-glucose treatment of endothelial cells induces autophagy by reactive oxygen species-mediated activation of the AMP-activated protein kinase. PLoS One 6: e17234.
-
(2011)
PLoS One
, vol.6
-
-
Wang, Q.1
Liang, B.2
Shirwany, N.3
Zou, M.4
-
23
-
-
64349115078
-
AMPK in the brain: its roles in energy balance and neuroprotection
-
Ronnett G, Ramamurthy S, Kleman A, Landree L, Aja S, (2009) AMPK in the brain: its roles in energy balance and neuroprotection. J Neurochem 109Suppl 1: 17-23.
-
(2009)
J Neurochem
, vol.109
, pp. 17-23
-
-
Ronnett, G.1
Ramamurthy, S.2
Kleman, A.3
Landree, L.4
Aja, S.5
-
24
-
-
0031007065
-
The AMP-activated protein kinase-fuel gauge of the mammalian cell?
-
Hardie D, Carling D, (1997) The AMP-activated protein kinase-fuel gauge of the mammalian cell? Eur J Biochem 246: 259-273.
-
(1997)
Eur J Biochem
, vol.246
, pp. 259-273
-
-
Hardie, D.1
Carling, D.2
-
25
-
-
78650848689
-
The emerging role of autophagy in the pathophysiology of diabetes mellitus
-
Gonzalez C, Lee M-S, Marchetti P, Pietropaolo M, Towns R, et al. (2011) The emerging role of autophagy in the pathophysiology of diabetes mellitus. Autophagy 7: 2-11.
-
(2011)
Autophagy
, vol.7
, pp. 2-11
-
-
Gonzalez, C.1
Lee, M.-S.2
Marchetti, P.3
Pietropaolo, M.4
Towns, R.5
-
26
-
-
52749092644
-
Autophagy: a sweet process in diabetes
-
Meijer A, Codogno P, (2008) Autophagy: a sweet process in diabetes. Cell metabolism 8: 275-276.
-
(2008)
Cell Metabolism
, vol.8
, pp. 275-276
-
-
Meijer, A.1
Codogno, P.2
-
27
-
-
1542742250
-
Expression of cone-photoreceptor-specific antigens in a cell line derived from retinal tumors in transgenic mice
-
Tan E, Ding X, Saadi A, Agarwal N, Naash M, et al. (2004) Expression of cone-photoreceptor-specific antigens in a cell line derived from retinal tumors in transgenic mice. Invest Ophthalmol Vis Sci 45: 764-768.
-
(2004)
Invest Ophthalmol Vis Sci
, vol.45
, pp. 764-768
-
-
Tan, E.1
Ding, X.2
Saadi, A.3
Agarwal, N.4
Naash, M.5
-
28
-
-
80053419807
-
Beclin 1-independent autophagy contributes to apoptosis in cortical neurons
-
Grishchuk Y, Ginet V, Truttmann A, Clarke P, Puyal J, (2011) Beclin 1-independent autophagy contributes to apoptosis in cortical neurons. Autophagy 7: 1115-1131.
-
(2011)
Autophagy
, vol.7
, pp. 1115-1131
-
-
Grishchuk, Y.1
Ginet, V.2
Truttmann, A.3
Clarke, P.4
Puyal, J.5
-
29
-
-
78751655392
-
Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis
-
Zhou F, Yang Y, Xing D, (2011) Bcl-2 and Bcl-xL play important roles in the crosstalk between autophagy and apoptosis. FEBS J 278: 403-413.
-
(2011)
FEBS J
, vol.278
, pp. 403-413
-
-
Zhou, F.1
Yang, Y.2
Xing, D.3
-
30
-
-
0036735949
-
Role of LAMP-2 in lysosome biogenesis and autophagy
-
Eskelinen E-L, Illert A, Tanaka Y, Schwarzmann Gn, Blanz J, et al. (2002) Role of LAMP-2 in lysosome biogenesis and autophagy. Molecular biology of the cell 13: 3355-3368.
-
(2002)
Molecular Biology of the Cell
, vol.13
, pp. 3355-3368
-
-
Eskelinen, E.-L.1
Illert, A.2
Tanaka, Y.3
Schwarzmann, G.4
Blanz, J.5
-
31
-
-
78650510609
-
mTOR: from growth signal integration to cancer, diabetes and ageing
-
Zoncu R, Efeyan A, Sabatini D, (2011) mTOR: from growth signal integration to cancer, diabetes and ageing. Nat Rev Mol Cell Biol 12: 21-35.
-
(2011)
Nat Rev Mol Cell Biol
, vol.12
, pp. 21-35
-
-
Zoncu, R.1
Efeyan, A.2
Sabatini, D.3
-
32
-
-
67349150186
-
Autophagy in human type 2 diabetes pancreatic beta cells
-
Masini M, Bugliani M, Lupi R, del Guerra S, Boggi U, et al. (2009) Autophagy in human type 2 diabetes pancreatic beta cells. Diabetologia 52: 1083-1086.
-
(2009)
Diabetologia
, vol.52
, pp. 1083-1086
-
-
Masini, M.1
Bugliani, M.2
Lupi, R.3
del Guerra, S.4
Boggi, U.5
-
33
-
-
33751549094
-
Increased oxygen radical formation and mitochondrial dysfunction mediate beta cell apoptosis under conditions of AMP-activated protein kinase stimulation
-
Cai Y, Martens G, Hinke S, Heimberg H, Pipeleers D, et al. (2007) Increased oxygen radical formation and mitochondrial dysfunction mediate beta cell apoptosis under conditions of AMP-activated protein kinase stimulation. Free Radic Biol Med 42: 64-78.
-
(2007)
Free Radic Biol Med
, vol.42
, pp. 64-78
-
-
Cai, Y.1
Martens, G.2
Hinke, S.3
Heimberg, H.4
Pipeleers, D.5
-
34
-
-
75749122303
-
Methods in mammalian autophagy research
-
Mizushima N, Yoshimori T, Levine B, (2010) Methods in mammalian autophagy research. Cell 140: 313-326.
-
(2010)
Cell
, vol.140
, pp. 313-326
-
-
Mizushima, N.1
Yoshimori, T.2
Levine, B.3
-
35
-
-
84862295360
-
Guidelines for the use and interpretation of assays for monitoring autophagy
-
Klionsky D, Abdalla F, Abeliovich H, Abraham R, Acevedo-Arozena A, et al. (2012) Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 8: 445-544.
-
(2012)
Autophagy
, vol.8
, pp. 445-544
-
-
Klionsky, D.1
Abdalla, F.2
Abeliovich, H.3
Abraham, R.4
Acevedo-Arozena, A.5
-
36
-
-
0034232418
-
Regulation of lamp2a levels in the lysosomal membrane
-
Cuervo A, Dice J, (2000) Regulation of lamp2a levels in the lysosomal membrane. Traffic (Copenhagen, Denmark) 1: 570-583.
-
(2000)
Traffic (Copenhagen, Denmark)
, vol.1
, pp. 570-583
-
-
Cuervo, A.1
Dice, J.2
-
37
-
-
43949112966
-
LAMP-2: a control step for phagosome and autophagosome maturation
-
Saftig P, Beertsen W, Eskelinen E-L, (2008) LAMP-2: a control step for phagosome and autophagosome maturation. Autophagy 4: 510-512.
-
(2008)
Autophagy
, vol.4
, pp. 510-512
-
-
Saftig, P.1
Beertsen, W.2
Eskelinen, E.-L.3
-
38
-
-
19244384656
-
Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice
-
Tanaka Y, Guhde G, Suter A, Eskelinen E, Hartmann D, et al. (2000) Accumulation of autophagic vacuoles and cardiomyopathy in LAMP-2-deficient mice. Nature 406: 902-906.
-
(2000)
Nature
, vol.406
, pp. 902-906
-
-
Tanaka, Y.1
Guhde, G.2
Suter, A.3
Eskelinen, E.4
Hartmann, D.5
-
39
-
-
36348984527
-
Danon disease as a cause of autophagic vacuolar myopathy
-
Yang Z, Vatta M, (2007) Danon disease as a cause of autophagic vacuolar myopathy. Congenital heart disease 2: 404-409.
-
(2007)
Congenital Heart Disease
, vol.2
, pp. 404-409
-
-
Yang, Z.1
Vatta, M.2
-
40
-
-
33846959828
-
Retinopathy in Danon disease
-
Schorderet D, Cottet S, Lobrinus J, Borruat Fo-X, Balmer A, et al. (2007) Retinopathy in Danon disease. Archives of ophthalmology 125: 231-236.
-
(2007)
Archives of Ophthalmology
, vol.125
, pp. 231-236
-
-
Schorderet, D.1
Cottet, S.2
Lobrinus, J.3
Borruat, F.-X.4
Balmer, A.5
-
41
-
-
33646915987
-
Ophthalmic manifestations of Danon disease
-
Prall F, Drack A, Taylor M, Ku L, Olson J, et al. (2006) Ophthalmic manifestations of Danon disease. Ophthalmology 113: 1010-1013.
-
(2006)
Ophthalmology
, vol.113
, pp. 1010-1013
-
-
Prall, F.1
Drack, A.2
Taylor, M.3
Ku, L.4
Olson, J.5
-
42
-
-
84862901711
-
Cone-rod dystrophy can be a manifestation of Danon disease
-
Thiadens A, Slingerland N, Florijn R, Visser G, Riemslag F, et al. (2012) Cone-rod dystrophy can be a manifestation of Danon disease. Graefe's archive for clinical and experimental ophthalmology 250: 769-774.
-
(2012)
Graefe's Archive for Clinical and Experimental Ophthalmology
, vol.250
, pp. 769-774
-
-
Thiadens, A.1
Slingerland, N.2
Florijn, R.3
Visser, G.4
Riemslag, F.5
-
43
-
-
84858659826
-
Inhibitory effect of dietary lipids on chaperone-mediated autophagy
-
Rodriguez-Navarro J, Kaushik S, Koga H, Dall'Armi C, Shui G, et al. (2012) Inhibitory effect of dietary lipids on chaperone-mediated autophagy. Proceedings of the National Academy of Sciences of the United States of America 109: 14.
-
(2012)
Proceedings of the National Academy of Sciences of the United States of America
, vol.109
, pp. 14
-
-
Rodriguez-Navarro, J.1
Kaushik, S.2
Koga, H.3
Dall'Armi, C.4
Shui, G.5
-
44
-
-
25144457455
-
Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
-
Pattingre S, Tassa A, Qu X, Garuti R, Liang X, et al. (2005) Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy. Cell 122: 927-939.
-
(2005)
Cell
, vol.122
, pp. 927-939
-
-
Pattingre, S.1
Tassa, A.2
Qu, X.3
Garuti, R.4
Liang, X.5
-
45
-
-
34248998801
-
Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1
-
Maiuri M, Le Toumelin G, Criollo A, Rain J, Gautier F, et al. (2007) Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1. EMBO J 26: 2527-2539.
-
(2007)
EMBO J
, vol.26
, pp. 2527-2539
-
-
Maiuri, M.1
Le Toumelin, G.2
Criollo, A.3
Rain, J.4
Gautier, F.5
-
46
-
-
77951217000
-
Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase
-
Wu Y-T, Tan H-L, Shui G, Bauvy C, Huang Q, et al. (2010) Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase. The Journal of biological chemistry 285: 10850-10861.
-
(2010)
The Journal of Biological Chemistry
, vol.285
, pp. 10850-10861
-
-
Wu, Y.-T.1
Tan, H.-L.2
Shui, G.3
Bauvy, C.4
Huang, Q.5
-
47
-
-
84869147050
-
Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation
-
Wang R, Wei Y, An Z, Zou Z, Xiao G, et al. (2012) Akt-mediated regulation of autophagy and tumorigenesis through Beclin 1 phosphorylation. Science (New York, NY) 338: 956-959.
-
(2012)
Science (New York, NY)
, vol.338
, pp. 956-959
-
-
Wang, R.1
Wei, Y.2
An, Z.3
Zou, Z.4
Xiao, G.5
-
48
-
-
84555195156
-
Nutrient sensing, autophagy, and diabetic nephropathy
-
Kume S, Thomas M, Koya D, (2012) Nutrient sensing, autophagy, and diabetic nephropathy. Diabetes 61: 23-29.
-
(2012)
Diabetes
, vol.61
, pp. 23-29
-
-
Kume, S.1
Thomas, M.2
Koya, D.3
-
49
-
-
84875416620
-
Stimulation of autophagy improves endoplasmic reticulum stress-induced diabetes
-
Bachar-Wikstrom E, Wikstrom J, Ariav Y, Tirosh B, Kaiser N, et al. (2013) Stimulation of autophagy improves endoplasmic reticulum stress-induced diabetes. Diabetes 62: 1227-1237.
-
(2013)
Diabetes
, vol.62
, pp. 1227-1237
-
-
Bachar-Wikstrom, E.1
Wikstrom, J.2
Ariav, Y.3
Tirosh, B.4
Kaiser, N.5
-
50
-
-
84877315340
-
Improvement of ER stress-induced diabetes by stimulating autophagy
-
Bachar-Wikstrom E, Wikstrom J, Kaiser N, Cerasi E, Leibowitz G, (2013) Improvement of ER stress-induced diabetes by stimulating autophagy. Autophagy 9: 626-628.
-
(2013)
Autophagy
, vol.9
, pp. 626-628
-
-
Bachar-Wikstrom, E.1
Wikstrom, J.2
Kaiser, N.3
Cerasi, E.4
Leibowitz, G.5
-
51
-
-
39849109338
-
Autophagy fights disease through cellular self-digestion
-
Mizushima N, Levine B, Cuervo A, Klionsky D, (2008) Autophagy fights disease through cellular self-digestion. Nature 451: 1069-1075.
-
(2008)
Nature
, vol.451
, pp. 1069-1075
-
-
Mizushima, N.1
Levine, B.2
Cuervo, A.3
Klionsky, D.4
-
52
-
-
77954116814
-
Autophagy gone awry in neurodegenerative diseases
-
Wong E, Cuervo A, (2010) Autophagy gone awry in neurodegenerative diseases. Nature neuroscience 13: 805-811.
-
(2010)
Nature Neuroscience
, vol.13
, pp. 805-811
-
-
Wong, E.1
Cuervo, A.2
|