Acute hypoglycemia decreases central retinal function in the human eye

Vision Research

Volumn 51, Issue 14, 2011, Pages 1623-1626

  Khan, Mukhtar I ^a   Barlow, Robert B ^a   Weinstock, Ruth S ^a  

^a SUNY UPSTATE MEDICAL UNIVERSITY   (United States)

Author keywords

Central retina; Contrast sensitivity; Diabetes; Hypoglycemia

Indexed keywords

INSULIN;

ADULT; ARTICLE; CLINICAL ARTICLE; CONTRAST SENSITIVITY; CONTROLLED STUDY; ELECTRORETINOGRAPHY; FEMALE; GLUCOSE BLOOD LEVEL; HEMOGLOBIN BLOOD LEVEL; HUMAN; HYPOGLYCEMIA; INSULIN DEPENDENT DIABETES MELLITUS; MALE; PILOT STUDY; PRIORITY JOURNAL; RETINA; RETINA FOVEA; RETINA MACULA LUTEA; SCOTOMA; VISUAL FIELD;

ACUTE DISEASE; ADULT; BLOOD GLUCOSE; CASE-CONTROL STUDIES; CONTRAST SENSITIVITY; DEPTH PERCEPTION; DIABETES MELLITUS, TYPE 1; DIABETIC RETINOPATHY; ELECTRORETINOGRAPHY; FEMALE; FOVEA CENTRALIS; GLUCOSE CLAMP TECHNIQUE; HUMANS; HYPOGLYCEMIA; MACULA LUTEA; MALE; PILOT PROJECTS; REACTION TIME; YOUNG ADULT;

EID: 79960912977     PISSN: 00426989     EISSN: 18785646     Source Type: Journal    
DOI: 10.1016/j.visres.2011.05.003     Document Type: Article

References (20)

1. Andres R., Swerdloff R., Pozefsky T., Coleman D. Manual feedback technique for the control of blood glucose concentration. Automation in analytical chemistry 1966, 486-491. Mediad Inc., White Plains. L. Skeggs (Ed.).
2. Bearse M.A., Sutter E.E. Imaging localized retinal dysfunction with the multifocal electroretinogram. Journal of the Optical Society of America A - Optics Image Science and Vision 1996, 13:634-640.
3. Cryer P.E. The barrier of hypoglycemia in diabetes. Diabetes 2008, 57:3169-3176.
4. Curcio C.A., Sloan K.R., Kalina R.E., Hendrickson A.E. Human photoreceptor topography. Journal of Comparative Neurology 1990, 292:497-523.
5. Goldgewicht C., Slama G., Papoz L., Tchobroutsky G. Hypoglycaemic reactions in 172 type 1 (insulin-dependent) diabetic patients. Diabetologia 1983, 24:95-99.
6. Hepburn D.A., Deary I.J., Frier B.M., Patrick A.W., Quinn J.D., Fisher B.M. Symptoms of acute insulin-induced hypoglycemia in humans with and without IDDM. Factor-analysis approach. Diabetes Care 1991, 14:949-957.
7. Hood D.C. Assessing retinal function with the multifocal technique. Progress in Retinal & Eye Research 2000, 19:607-646.
8. Hood D.C., Seiple W., Holopigian K., Greenstein V. A comparison of the components of the multifocal and full-field ERGs. Visual Neuroscience 1997, 14:533-544.
9. Liu D., Moberg E., Kollind M., Lins P.E., Adamson U., Macdonald I.A. Arterial, arterialized venous, venous and capillary blood glucose measurements in normal man during hyperinsulinaemic euglycaemia and hypoglycaemia. Diabetologia 1992, 35:287-290.
10. Macaluso C., Onoe S., Niemeyer G. Changes in glucose level affect rod function more than cone function in the isolated, perfused cat eye. Investigative Ophthalmology and Visual Science 1992, 33:2798-2808.
11. Marmor M.F., Hood D.C., Keating D., Kondo M., Seeliger M.W., Miyake Y. Guidelines for basic multifocal electroretinography (mfERG). Documenta Ophthalmologica 2003, 106:105-115.
12. McCrimmon R.J., Deary I.J., Huntly B.J., MacLeod K.J., Frier B.M. Visual information processing during controlled hypoglycaemia in humans. Brain 1996, 119:1277-1287.
13. McFarland R.A., Halperin M.H., Niven J.J. Visual thresholds as an index of physiological imbalance during insulin hypoglycemia. American Journal of Physiology 1946, 145:299-313.
14. Perlmuter L.C., Flanagan B.P., Shah P.H., Singh S.P. Glycemic control and hypoglycemia. Diabetes Care 2008, 31:2072-2076.
15. Provis J.M. Development of the primate retinal vasculature. Progress in Retinal & Eye Research. 2001, 20:799-821.
16. Sutter E.E., Tran D. The field topography of ERG components in man - I. The photopic luminance response. Vision Research 1992, 32:433-446.
17. Tabandeh H., Ranganath L., Marks V. Visual function during acute hypoglycaemia. European Journal of Ophthalmology 1996, 6:81-86.
18. Umino Y., Everhart D., Solessio E., Cusato K., Pan J.C., Nguyen T.H., et al. Hypoglycemia leads to age-related loss of vision. Proceedings of the National Academy of Sciences of The United States of America 2006, 103:19541-19545.
19. Winkler B.S. Glycolytic and oxidative metabolism in relation to retinal function. Journal of General Physiology 1981, 77:667-692.
20. Wybar K.C. A study of the choroidal circulation of the eye in man. Journal of Anatomy 1954, 88:94-98.