Protective effects of the total saponins from Rosa laevigata Michx fruit against carbon tetrachloride-induced acute liver injury in mice

Food and Chemical Toxicology

Volumn 62, Issue , 2013, Pages 120-130

  Dong, Deshi ^a   Zhang, Shuai ^a   Yin, Lianhong ^a   Tang, Xinqiang ^a   Xu, Youwei ^a   Han, Xu ^a   Qi, Yan ^a   Peng, Jinyong ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

Author keywords

Acute liver injury; Carbon tetrachloride; Hepatoprotective effect; Rosa laevigata Michx; Total saponins

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; CASPASE 3; CASPASE 9; CATALASE; CYCLOOXYGENASE 2; CYTOCHROME P450 2E1; CYTOKERATIN 18; FAS LIGAND; GLUCOSE REGULATED PROTEIN 78; GLUTATHIONE; GLUTATHIONE PEROXIDASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INITIATION FACTOR 2; INTERLEUKIN 6; MALONALDEHYDE; MITOGEN ACTIVATED PROTEIN KINASE; NITRIC OXIDE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; SAPONIN; SILYMARIN; SUPEROXIDE DISMUTASE; TUMOR NECROSIS FACTOR ALPHA; PROTECTIVE AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; DNA FRAGMENTATION; DOWN REGULATION; DRUG STRUCTURE; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GENE EXPRESSION; HISTOLOGY; LIVER PROTECTION; LIVER TOXICITY; LIVER WEIGHT; MALE; MEDICINAL PLANT; MOUSE; NICK END LABELING; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; ROSA LAEVIGATA; TRANSMISSION ELECTRON MICROSCOPY; UPREGULATION; ANIMAL; BLOOD; CHEMISTRY; DRUG EFFECTS; DRUG-INDUCED LIVER INJURY; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION; ISOLATION AND PURIFICATION; LIQUID CHROMATOGRAPHY; LIVER; METABOLISM; PATHOLOGY; PROCEDURES; ROSE;

ALANINE TRANSAMINASE; ANIMALS; ASPARTATE AMINOTRANSFERASES; CARBON TETRACHLORIDE; CHROMATOGRAPHY, LIQUID; CYTOCHROME P-450 CYP2E1; DRUG-INDUCED LIVER INJURY; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION REGULATION; LIVER; MALE; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; PROTECTIVE AGENTS; ROSA; SAPONINS;

EID: 84884155707     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2013.08.050     Document Type: Article

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