-
1
-
-
0003570458
-
Biochemistry and Molecular Biology of Parasites
-
(eds), Academic Press, New York.
-
Marr, J.J. and Müller, M. (eds) (1995) Biochemistry and Molecular Biology of Parasites, Academic Press, New York.
-
(1995)
-
-
Marr, J.J.1
Müller, M.2
-
2
-
-
4444269464
-
Molecular Medical Parasitology
-
(eds), Academic Press, London.
-
Marr, J.J., Nelsen, T.W. and Komuniecki, R.W. (eds) (2003) Molecular Medical Parasitology, Academic Press, London.
-
(2003)
-
-
Marr, J.J.1
Nelsen, T.W.2
Komuniecki, R.W.3
-
3
-
-
84890978994
-
Energy metabolism
-
in, (ed. H. Mehlhorn), SpringerVerlag, Berlin
-
Kohler, P. and Tielens, A.G.M. (2008) Energy metabolism, in Encyclopedia of Parasitology (ed. H. Mehlhorn), SpringerVerlag, Berlin, pp. 460-472.
-
(2008)
Encyclopedia of Parasitology
, pp. 460-472
-
-
Kohler, P.1
Tielens, A.G.M.2
-
4
-
-
0032429638
-
The pyrophosphate-dependent phosphofructokinase of the protist, Trichomonas vaginalis, and the evolutionary relationships of protist phosphofructokinases
-
Mertens, E., Ladror, U.S., Lee, J.A., Miretsky, A., Morris, A., Rozario, C., Kemp, R.G. and Muller, M. (1998) The pyrophosphate-dependent phosphofructokinase of the protist, Trichomonas vaginalis, and the evolutionary relationships of protist phosphofructokinases. Journal of Molecular Evolution, 47, 739-750.
-
(1998)
Journal of Molecular Evolution
, vol.47
, pp. 739-750
-
-
Mertens, E.1
Ladror, U.S.2
Lee, J.A.3
Miretsky, A.4
Morris, A.5
Rozario, C.6
Kemp, R.G.7
Muller, M.8
-
5
-
-
0032007547
-
Cloning and expression of the gene for the active PPi-dependent phosphofructokinase of Entamoeba histolytica
-
Deng, Z., Huang, M., Singh, K., Albach, R.A., Latshaw, S.P., Chang, K.-P. and Kemp, R.G. (1998) Cloning and expression of the gene for the active PPi-dependent phosphofructokinase of Entamoeba histolytica. The Biochemical Journal, 329, 659-664.
-
(1998)
The Biochemical Journal
, vol.329
, pp. 659-664
-
-
Deng, Z.1
Huang, M.2
Singh, K.3
Albach, R.A.4
Latshaw, S.P.5
Chang, K.-P.6
Kemp, R.G.7
-
6
-
-
0030824910
-
Involvement and identification of a lysine in the PPi-site of pyrophosphate-dependent phosphofructokinase from Giardia lamblia
-
Li, Z. and Phillips, N.F. (1997) Involvement and identification of a lysine in the PPi-site of pyrophosphate-dependent phosphofructokinase from Giardia lamblia. Biochimie, 79, 221-227.
-
(1997)
Biochimie
, vol.79
, pp. 221-227
-
-
Li, Z.1
Phillips, N.F.2
-
7
-
-
0035827580
-
The two phosphofructokinase gene products of Entamoeba histolytica
-
Chi, A.S., Deng, Z., Albach, R.A. and Kemp, R.G. (2001) The two phosphofructokinase gene products of Entamoeba histolytica. The Journal of Biological Chemistry, 276, 19974-19981.
-
(2001)
The Journal of Biological Chemistry
, vol.276
, pp. 19974-19981
-
-
Chi, A.S.1
Deng, Z.2
Albach, R.A.3
Kemp, R.G.4
-
8
-
-
0036094071
-
The Structure of a pyrophosphate-dependent phosphofructokinase from the Lyme disease spirochete Borrelia burgdorferi
-
London, England: 1993
-
Moore, S.A., Ron, S., Ronimus, R.S., Roberson, R.S. and Morgan, H.W. (2002) The Structure of a pyrophosphate-dependent phosphofructokinase from the Lyme disease spirochete Borrelia burgdorferi. Structure (London, England: 1993), 10, 659-671.
-
(2002)
Structure
, vol.10
, pp. 659-671
-
-
Moore, S.A.1
Ron, S.2
Ronimus, R.S.3
Roberson, R.S.4
Morgan, H.W.5
-
9
-
-
0012931110
-
Chemotherapeutic Targets in Parasites
-
(ed.), Cambridge University Press
-
Mansour, T.E. (ed.) (2002) Chemotherapeutic Targets in Parasites, Cambridge University Press, pp. 143-145.
-
(2002)
, pp. 143-145
-
-
Mansour, T.E.1
-
10
-
-
9144255536
-
Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo
-
Ghosh, S., Chan, J.M., Lea, C.R., Meints, G.A., Lewis, J.C., Tovian, Z.S., Flessner, R.M. et al. (2004) Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo. Journal of Medicinal Chemistry, 47, 175-187.
-
(2004)
Journal of Medicinal Chemistry
, vol.47
, pp. 175-187
-
-
Ghosh, S.1
Chan, J.M.2
Lea, C.R.3
Meints, G.A.4
Lewis, J.C.5
Tovian, Z.S.6
Flessner, R.M.7
-
11
-
-
0032742093
-
Purification and characterization of recombinant pyruvate phosphate dikinase from Giardia
-
Hiltpold, A., Thomas, R.M. and Kohler, P. (1999) Purification and characterization of recombinant pyruvate phosphate dikinase from Giardia. Molecular and Biochemical Parasitology, 104, 157-169.
-
(1999)
Molecular and Biochemical Parasitology
, vol.104
, pp. 157-169
-
-
Hiltpold, A.1
Thomas, R.M.2
Kohler, P.3
-
12
-
-
30944435242
-
Pyruvate-phosphate dikinase of oxymonads and Parabasalia and the evolution of pyrophosphate-dependent glycolysis in anaerobic eukaryotes
-
Slamovits, C.H., Patrick, J. and Keeling, P.J. (2006) Pyruvate-phosphate dikinase of oxymonads and Parabasalia and the evolution of pyrophosphate-dependent glycolysis in anaerobic eukaryotes. Eukaryotic Cell, 5, 148-154.
-
(2006)
Eukaryotic Cell
, vol.5
, pp. 148-154
-
-
Slamovits, C.H.1
Patrick, J.2
Keeling, P.J.3
-
13
-
-
0035983518
-
The 3.0 Å resolution crystal structure of glycosomal pyruvate phosphate dikinase from Trypanosoma brucei
-
Cosenza, L.W., Bringaud, F., Baltz, T. and Vellieux, F.M.D. (2002) The 3.0 Å resolution crystal structure of glycosomal pyruvate phosphate dikinase from Trypanosoma brucei. Journal of Molecular Biology, 318, 1417-1432.
-
(2002)
Journal of Molecular Biology
, vol.318
, pp. 1417-1432
-
-
Cosenza, L.W.1
Bringaud, F.2
Baltz, T.3
Vellieux, F.M.D.4
-
14
-
-
13444291928
-
Crystal structures of pyruvate phosphate dikinase from maize revealed an alternative conformation in the swiveling-domain motion
-
Nakanishi, T., Nakatsu, T., Matsuoka, M., Sakata, K. and Kato, H. (2005) Crystal structures of pyruvate phosphate dikinase from maize revealed an alternative conformation in the swiveling-domain motion. Biochemistry, 44, 1136-1144.
-
(2005)
Biochemistry
, vol.44
, pp. 1136-1144
-
-
Nakanishi, T.1
Nakatsu, T.2
Matsuoka, M.3
Sakata, K.4
Kato, H.5
-
15
-
-
50249121995
-
Molecular modeling on pyruvate phosphate dikinase of Entamoeba histolytica and in silico virtual screening for novel inhibitors
-
Stephen, P., Vijayan, R., Bhat, A., Subbarao, A.N. and Bamezai, R.N.K. (2008) Molecular modeling on pyruvate phosphate dikinase of Entamoeba histolytica and in silico virtual screening for novel inhibitors. Journal of Computer-Aided Molecular Design, 22, 647-660.
-
(2008)
Journal of Computer-Aided Molecular Design
, vol.22
, pp. 647-660
-
-
Stephen, P.1
Vijayan, R.2
Bhat, A.3
Subbarao, A.N.4
Bamezai, R.N.K.5
-
16
-
-
0028874227
-
Primary structure and eubacterial relationship of pyruvate: ferredoxin oxidoreductase of the amitochondriate eukaryote Trichomonas vaginalis
-
Hrdy, I. and Muller, M. (1995) Primary structure and eubacterial relationship of pyruvate: ferredoxin oxidoreductase of the amitochondriate eukaryote Trichomonas vaginalis. Journal of Molecular Evolution, 41, 388-396.
-
(1995)
Journal of Molecular Evolution
, vol.41
, pp. 388-396
-
-
Hrdy, I.1
Muller, M.2
-
17
-
-
0342561564
-
Cloning and characterization of the Entamoeba histolytica pyruvate: ferredoxin oxidoreductase gene
-
Rodriguez, M.A., Hidalgo, M.E., Sánchez, T. and Orozco, E. (1996) Cloning and characterization of the Entamoeba histolytica pyruvate: ferredoxin oxidoreductase gene. Molecular and Biochemical Parasitology, 78, 273-277.
-
(1996)
Molecular and Biochemical Parasitology
, vol.78
, pp. 273-277
-
-
Rodriguez, M.A.1
Hidalgo, M.E.2
Sánchez, T.3
Orozco, E.4
-
18
-
-
0030221888
-
Characterisation and purification of pyruvate:ferredoxin oxidoreductase from Giardia duodenalis
-
Townson, S.M., Upcrof, J.A. and Upcroft, P. (1996) Characterisation and purification of pyruvate:ferredoxin oxidoreductase from Giardia duodenalis. Molecular and Biochemical Parasitology, 79, 183-193.
-
(1996)
Molecular and Biochemical Parasitology
, vol.79
, pp. 183-193
-
-
Townson, S.M.1
Upcrof, J.A.2
Upcroft, P.3
-
19
-
-
32044451080
-
Flexibility of thiamine diphosphate revealed by kinetic crystallographic studies of the reaction of pyruvate-ferredoxin oxidoreductase with pyruvate
-
London, England: 1993
-
Cavazza, C., Contreras-Martel, C., Pieulle, L., Chabriere, E., Hatchikian, E.C. and Fontecilla-Camps, J.C. (2006) Flexibility of thiamine diphosphate revealed by kinetic crystallographic studies of the reaction of pyruvate-ferredoxin oxidoreductase with pyruvate. Structure (London, England: 1993), 14, 217-224.
-
(2006)
Structure
, vol.14
, pp. 217-224
-
-
Cavazza, C.1
Contreras-Martel, C.2
Pieulle, L.3
Chabriere, E.4
Hatchikian, E.C.5
Fontecilla-Camps, J.C.6
-
20
-
-
0035138734
-
Drug targets and mechanisms of resistance in the anaerobic protozoa
-
Upcroft, P. and Upcroft, J.A. (2001) Drug targets and mechanisms of resistance in the anaerobic protozoa. Clinical Microbiology Reviews, 14, 150-164.
-
(2001)
Clinical Microbiology Reviews
, vol.14
, pp. 150-164
-
-
Upcroft, P.1
Upcroft, J.A.2
-
21
-
-
33846503255
-
Current therapeutics, their problems, and sulfur-containing-amino-acid metabolism as a novel target against infections by 'amitochondriate' protozoan parasites
-
Ali, V. and Nozaki, T. (2007) Current therapeutics, their problems, and sulfur-containing-amino-acid metabolism as a novel target against infections by 'amitochondriate' protozoan parasites. Clinical Microbiology Reviews, 20, 164-187.
-
(2007)
Clinical Microbiology Reviews
, vol.20
, pp. 164-187
-
-
Ali, V.1
Nozaki, T.2
-
22
-
-
38149112907
-
Kinetic characterization of methionine gamma-lyases from the enteric protozoan parasite Entamoeba histolytica against physiological substrates and trifluoromethionine, a promising lead compound against amoebiasis
-
Sato, D., Yamagata, W., Harada, S. and Nozaki, T. (2008) Kinetic characterization of methionine gamma-lyases from the enteric protozoan parasite Entamoeba histolytica against physiological substrates and trifluoromethionine, a promising lead compound against amoebiasis. FEBS Journal, 275, 548-560.
-
(2008)
FEBS Journal
, vol.275
, pp. 548-560
-
-
Sato, D.1
Yamagata, W.2
Harada, S.3
Nozaki, T.4
-
23
-
-
33749508864
-
Expression, purification and crystallization of L-methionine gamma-lyase 2 from Entamoeba histolytica
-
Sato, D., Yamagata, W., Kamei, K., Nozaki, T. and Harada, S. (2006) Expression, purification and crystallization of L-methionine gamma-lyase 2 from Entamoeba histolytica. Acta Crystallographica, Section F: Structure, Biology and Crystallography Communications, 62, 1034-1036.
-
(2006)
Acta Crystallographica, Section F: Structure, Biology and Crystallography Communications
, vol.62
, pp. 1034-1036
-
-
Sato, D.1
Yamagata, W.2
Kamei, K.3
Nozaki, T.4
Harada, S.5
-
24
-
-
38149061604
-
Structure of the antitumour enzyme L-methionine gamma-lyase from Pseudomonas putida at 1.8 A resolution
-
Kudou, D., Misaki, S., Yamashita, M., Tamura, T., Takakura, T., Yoshioka, T., Yagi, S. et al. (2007) Structure of the antitumour enzyme L-methionine gamma-lyase from Pseudomonas putida at 1.8 A resolution. Journal of Biochemistry, 141, 535-544.
-
(2007)
Journal of Biochemistry
, vol.141
, pp. 535-544
-
-
Kudou, D.1
Misaki, S.2
Yamashita, M.3
Tamura, T.4
Takakura, T.5
Yoshioka, T.6
Yagi, S.7
-
25
-
-
2442696023
-
Determination of the sites required for the allosteric inhibition of serine acetyltrans-ferase by L-cysteine in plants
-
Inoue, K., Noji, M. and Sait, K. (1999) Determination of the sites required for the allosteric inhibition of serine acetyltrans-ferase by L-cysteine in plants. European Journal of Biochemistry, 266, 220-227.
-
(1999)
European Journal of Biochemistry
, vol.266
, pp. 220-227
-
-
Inoue, K.1
Noji, M.2
Sait, K.3
-
26
-
-
33748755115
-
Cysteine biosynthesis in Trichomonas vaginalis involves cysteine synthase utilizing O-phosphoserine
-
Westrop, G.D., Goodall, G., Mottram, J.C. and Coombs, G.H. (2006) Cysteine biosynthesis in Trichomonas vaginalis involves cysteine synthase utilizing O-phosphoserine. The Journal of Biological Chemistry, 281, 25062-25075.
-
(2006)
The Journal of Biological Chemistry
, vol.281
, pp. 25062-25075
-
-
Westrop, G.D.1
Goodall, G.2
Mottram, J.C.3
Coombs, G.H.4
-
27
-
-
22444433528
-
Three-dimensional structure of a new enzyme, O-phosphoserine sulfhydrylase, involved in L-cysteine biosynthesis by a hyperthermophilic archaeon, Aeropyrum pernix K1, at 2.0 Å resolution
-
Oda, Y., Mino, K., Ishikawa, K. and Ataka, M. (2005) Three-dimensional structure of a new enzyme, O-phosphoserine sulfhydrylase, involved in L-cysteine biosynthesis by a hyperthermophilic archaeon, Aeropyrum pernix K1, at 2.0 Å resolution. Journal of Molecular Biology, 351, 334-344.
-
(2005)
Journal of Molecular Biology
, vol.351
, pp. 334-344
-
-
Oda, Y.1
Mino, K.2
Ishikawa, K.3
Ataka, M.4
-
28
-
-
33644884736
-
Engineering of Escherichia coli L-serine O-acetyltransferase on the basis of crystal structure: desensitization to feedback inhibition by L-cysteine
-
Kai, Y., Kashiwagi, T., Ishikawa, K., Ziyatdinov, M.K., Redkina, E.I., Kiriukhin, M.Y., Gusyatiner, M.M. et al. (2006) Engineering of Escherichia coli L-serine O-acetyltransferase on the basis of crystal structure: desensitization to feedback inhibition by L-cysteine. Protein Engin Design Select, 19, 163-167.
-
(2006)
Protein Engin Design Select
, vol.19
, pp. 163-167
-
-
Kai, Y.1
Kashiwagi, T.2
Ishikawa, K.3
Ziyatdinov, M.K.4
Redkina, E.I.5
Kiriukhin, M.Y.6
Gusyatiner, M.M.7
-
29
-
-
37249032585
-
Inhibitors of Escherichia coli serine acetyltransferase block proliferation of Entamoeba histolytica trophozoites
-
Agarwal, S.M., Jain, R., Bhattacharya, A. and Azam, A. (2008) Inhibitors of Escherichia coli serine acetyltransferase block proliferation of Entamoeba histolytica trophozoites. International Journal for Parasitology, 38, 137-141.
-
(2008)
International Journal for Parasitology
, vol.38
, pp. 137-141
-
-
Agarwal, S.M.1
Jain, R.2
Bhattacharya, A.3
Azam, A.4
-
30
-
-
34848818562
-
High resolution structure and catalysis of O-acetylserine sulfhydrylase isozyme B from Escherichia coli
-
Zocher, G., Wiesand, U. and Schulz, G.E. (2007) High resolution structure and catalysis of O-acetylserine sulfhydrylase isozyme B from Escherichia coli. FEBS Journal, 274, 5382-5389.
-
(2007)
FEBS Journal
, vol.274
, pp. 5382-5389
-
-
Zocher, G.1
Wiesand, U.2
Schulz, G.E.3
-
31
-
-
34447554594
-
Structure, mechanism, and conformational dynamics of O-acetylserine sulfhydrylase from Salmonella typhimurium: Comparison of A and B Isozymes
-
Chattopadhyay, A., Meier, M., Ivaninskii, S. and Burkhard, P. (2007) Structure, mechanism, and conformational dynamics of O-acetylserine sulfhydrylase from Salmonella typhimurium: Comparison of A and B Isozymes. Biochemistry, 46, 8315-8330.
-
(2007)
Biochemistry
, vol.46
, pp. 8315-8330
-
-
Chattopadhyay, A.1
Meier, M.2
Ivaninskii, S.3
Burkhard, P.4
-
32
-
-
34548188995
-
Structural insights into catalysis and inhibition of O-acetylserine sulfhydrylase from Mycobacterium tuberculosis. Crystal structures of the enzyme a-aminoacrylate intermediate and an enzyme inhibitor complex
-
Schnell, R., Oehlmann, W., Singh, M. and Schneider, G. (2007) Structural insights into catalysis and inhibition of O-acetylserine sulfhydrylase from Mycobacterium tuberculosis. Crystal structures of the enzyme a-aminoacrylate intermediate and an enzyme inhibitor complex. The Journal of Biological Chemistry, 282, 23473-23481.
-
(2007)
The Journal of Biological Chemistry
, vol.282
, pp. 23473-23481
-
-
Schnell, R.1
Oehlmann, W.2
Singh, M.3
Schneider, G.4
-
33
-
-
34249936787
-
Crystallization and preliminary crystallographic analysis of cysteine synthase from Entamoeba histolytica
-
Krishna, C., Jain, R., Kashav, T., Wadhwa, D., Alam, N. and Gourinath, S. (2007) Crystallization and preliminary crystallographic analysis of cysteine synthase from Entamoeba histolytica. Acta Crystallographica, Section F: Structure, Biology and Crystallography Communications, 63, 512-515.
-
(2007)
Acta Crystallographica, Section F: Structure, Biology and Crystallography Communications
, vol.63
, pp. 512-515
-
-
Krishna, C.1
Jain, R.2
Kashav, T.3
Wadhwa, D.4
Alam, N.5
Gourinath, S.6
-
34
-
-
14844334895
-
Trypanothione synthesis in Crithidia revisited
-
Comini, M., Menge, U., Wissing, J. and Flohe, L. (2005) Trypanothione synthesis in Crithidia revisited. The Journal of Biological Chemistry, 280, 6850-6860.
-
(2005)
The Journal of Biological Chemistry
, vol.280
, pp. 6850-6860
-
-
Comini, M.1
Menge, U.2
Wissing, J.3
Flohe, L.4
-
35
-
-
0033555451
-
Crystal structure of Trypanosoma cruzi trypanothione reductase in complex with trypanothione, and the structure-based discovery of new natural product inhibitors
-
London, England: 1993
-
Bond, C.S., Zhan, Y., Berriman, M., Cunningham, M.L., Fairlamb, A.H. and Hunter, W.N. (1999) Crystal structure of Trypanosoma cruzi trypanothione reductase in complex with trypanothione, and the structure-based discovery of new natural product inhibitors. Structure (London, England: 1993), 7, 81-89.
-
(1999)
Structure
, vol.7
, pp. 81-89
-
-
Bond, C.S.1
Zhan, Y.2
Berriman, M.3
Cunningham, M.L.4
Fairlamb, A.H.5
Hunter, W.N.6
-
36
-
-
3142719178
-
Two interacting binding sites for quinacrine derivatives in the active site of trypanothione reductase: a template for drug design
-
Saravanamuthu, A., Vickers, T.J., Bond, C.S., Peterson, M.R., Hunter, W.N. and Fairlamb, A.H. (2004) Two interacting binding sites for quinacrine derivatives in the active site of trypanothione reductase: a template for drug design. The Journal of Biological Chemistry, 279, 29493-29500.
-
(2004)
The Journal of Biological Chemistry
, vol.279
, pp. 29493-29500
-
-
Saravanamuthu, A.1
Vickers, T.J.2
Bond, C.S.3
Peterson, M.R.4
Hunter, W.N.5
Fairlamb, A.H.6
-
37
-
-
0033977079
-
Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress
-
Krieger, S., Schwarz, W., Ariyanayagam, M.R., Fairlamb, A.H., Krauth-Siegel, R.L. and Clayton, C. (2000) Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress. Molecular Microbiology, 35, 542-552.
-
(2000)
Molecular Microbiology
, vol.35
, pp. 542-552
-
-
Krieger, S.1
Schwarz, W.2
Ariyanayagam, M.R.3
Fairlamb, A.H.4
Krauth-Siegel, R.L.5
Clayton, C.6
-
38
-
-
33846933089
-
High-throughput screening affords novel and selective trypanothione reductase inhibitors with anti-trypanosomal activity
-
Martyn, D.C., Jones, D.C., Fairlamb, A.H. and Clardy, J. (2007) High-throughput screening affords novel and selective trypanothione reductase inhibitors with anti-trypanosomal activity. Bioorganic & Medicinal Chemistry Letters, 17, 1280-1283.
-
(2007)
Bioorganic & Medicinal Chemistry Letters
, vol.17
, pp. 1280-1283
-
-
Martyn, D.C.1
Jones, D.C.2
Fairlamb, A.H.3
Clardy, J.4
-
39
-
-
33748309413
-
Trypanosome alternative oxidase: from molecule to function
-
Chaudhuri, M., Ott, R.D. and Hill, G.C. (2006) Trypanosome alternative oxidase: from molecule to function. Trends in Parasitology, 22, 484-491.
-
(2006)
Trends in Parasitology
, vol.22
, pp. 484-491
-
-
Chaudhuri, M.1
Ott, R.D.2
Hill, G.C.3
-
40
-
-
2442495286
-
Molecular cloning and characterization of Trypanosoma vivax alternative oxidase (AOX) gene, a target of the trypanocide ascofuranone
-
Suzuki, T., Nihei, C., Yabu, Y., Hashimoto, T., Suzuk, M., Yoshida, A., Nagai, K. et al. (2004) Molecular cloning and characterization of Trypanosoma vivax alternative oxidase (AOX) gene, a target of the trypanocide ascofuranone. Parasitology International, 53, 235-245.
-
(2004)
Parasitology International
, vol.53
, pp. 235-245
-
-
Suzuki, T.1
Nihei, C.2
Yabu, Y.3
Hashimoto, T.4
Suzuk, M.5
Yoshida, A.6
Nagai, K.7
-
41
-
-
31044443202
-
Chemotherapeutic efficacy of ascofuranone in Trypanosoma vivax-infected mice without glycerol
-
Yabu, Y., Suzuki, T., Nihei, C., Minagawa, N., Hosokaw, T., Nagai, K., Kita, K. et al. (2006) Chemotherapeutic efficacy of ascofuranone in Trypanosoma vivax-infected mice without glycerol. Parasitology International, 55, 39-43.
-
(2006)
Parasitology International
, vol.55
, pp. 39-43
-
-
Yabu, Y.1
Suzuki, T.2
Nihei, C.3
Minagawa, N.4
Hosokaw, T.5
Nagai, K.6
Kita, K.7
-
42
-
-
33846632321
-
Novel inhibitors of the trypanosome alternative oxidase inhibit Trypanosoma brucei brucei growth and respiration
-
Ott, R., Chibale, K., Anderson, S., Chipeleme, A., Chaudhuri, M., Guerrah, A., Colowick, N. and Hill, G.C. (2006) Novel inhibitors of the trypanosome alternative oxidase inhibit Trypanosoma brucei brucei growth and respiration. Acta Tropica, 100, 172-184.
-
(2006)
Acta Tropica
, vol.100
, pp. 172-184
-
-
Ott, R.1
Chibale, K.2
Anderson, S.3
Chipeleme, A.4
Chaudhuri, M.5
Guerrah, A.6
Colowick, N.7
Hill, G.C.8
-
43
-
-
0347357680
-
A complete shikimate pathway in Toxoplasma gondii: an ancient eukaryotic innovation
-
Campbell, S.A., Richards, T.A., Mui, E.J., Samuel, B.U., Coggins, J.R., McLeod, R. and Roberts, C.W. (2004) A complete shikimate pathway in Toxoplasma gondii: an ancient eukaryotic innovation. International Journal for Parasitology, 34, 5-13.
-
(2004)
International Journal for Parasitology
, vol.34
, pp. 5-13
-
-
Campbell, S.A.1
Richards, T.A.2
Mui, E.J.3
Samuel, B.U.4
Coggins, J.R.5
McLeod, R.6
Roberts, C.W.7
-
44
-
-
34547917580
-
Conservation of NADPH utilization by chorismate synthase and its implications for the evolution of the shikimate pathway
-
Ehammer, H., Rauch, G., Prem, A., Kappes, B. and Macheroux, P. (2007) Conservation of NADPH utilization by chorismate synthase and its implications for the evolution of the shikimate pathway. Molecular Microbiology, 65, 1249-1257.
-
(2007)
Molecular Microbiology
, vol.65
, pp. 1249-1257
-
-
Ehammer, H.1
Rauch, G.2
Prem, A.3
Kappes, B.4
Macheroux, P.5
-
45
-
-
9144259546
-
Crystal structure of the bifunctional chorismate synthase from Saccharomyces cerevisiae
-
Quevillon-Cheruel, S., Leulliot, N., Meyer, Ph., Graille, M., Bremang, M., Blondeau, K., Sorel, I. et al. (2003) Crystal structure of the bifunctional chorismate synthase from Saccharomyces cerevisiae. The Journal of Biological Chemistry, 279, 619-625.
-
(2003)
The Journal of Biological Chemistry
, vol.279
, pp. 619-625
-
-
Quevillon-Cheruel, S.1
Leulliot, N.2
Meyer, P.3
Graille, M.4
Bremang, M.5
Blondeau, K.6
Sorel, I.7
-
46
-
-
33745503978
-
Structure of chorismate synthase from Mycobacterium tuberculosis
-
Dias, M.V.B., Borges, J.C., Ely, F., Pereira, J.H., Canduri, F., Ramos, C.H.I., Frazzon, J. et al. (2006) Structure of chorismate synthase from Mycobacterium tuberculosis. Journal of Structural Biology, 154, 130-143.
-
(2006)
Journal of Structural Biology
, vol.154
, pp. 130-143
-
-
Dias, M.V.B.1
Borges, J.C.2
Ely, F.3
Pereira, J.H.4
Canduri, F.5
Ramos, C.H.I.6
Frazzon, J.7
-
47
-
-
33847723314
-
Chorismate synthase: An attractive target for drug development against orphan diseases
-
Dias, M.V.B., Ely, F., Palma, M.S., de Azevedo, W.F. Jr, Basso, L.A. and Santos, D.S. (2007) Chorismate synthase: An attractive target for drug development against orphan diseases. Current Drug Targets, 8, 437-444.
-
(2007)
Current Drug Targets
, vol.8
, pp. 437-444
-
-
Dias, M.V.B.1
Ely, F.2
Palma, M.S.3
De Azevedo Jr., W.F.4
Basso, L.A.5
Santos, D.S.6
-
48
-
-
78650743972
-
A computational approach to explore Plasmodium falciparum 3D7 chorismate synthase
-
Arora, N., Chari, U.V.N.M., Barnerjee, A.K. and Murty, U.S.N. (2007) A computational approach to explore Plasmodium falciparum 3D7 chorismate synthase. International Journal of Genomics and Proteomics, 3.
-
(2007)
International Journal of Genomics and Proteomics
, pp. 3
-
-
Arora, N.1
Chari, U.V.N.M.2
Barnerjee, A.K.3
Murty, U.S.N.4
-
49
-
-
33745659845
-
The 1.9 A resolution structure of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase, a potential drug target
-
Henriksson, L.M., Bjårkelid, C., Mowbray, S.L. and Unge, T. (2006) The 1.9 A resolution structure of Mycobacterium tuberculosis 1-deoxy-D-xylulose 5-phosphate reductoisomerase, a potential drug target. Biological Crystallography, 62, 807-813.
-
(2006)
Biological Crystallography
, vol.62
, pp. 807-813
-
-
Henriksson, L.M.1
Bjårkelid, C.2
Mowbray, S.L.3
Unge, T.4
-
50
-
-
34249940474
-
Structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase in a quaternary complex with a magnesium ion, NADPH and the antimalarial drug fosmidomycin
-
Yajima, S., Hara, K., Iino, D., Sasaki, Y., Kuzuyama, T., Ohsawa, K. and Seto, H. (2007) Structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase in a quaternary complex with a magnesium ion, NADPH and the antimalarial drug fosmidomycin. Acta Crystallographica, Section F: Structure, Biology and Crystallography Communications, 63, 466-470.
-
(2007)
Acta Crystallographica, Section F: Structure, Biology and Crystallography Communications
, vol.63
, pp. 466-470
-
-
Yajima, S.1
Hara, K.2
Iino, D.3
Sasaki, Y.4
Kuzuyama, T.5
Ohsawa, K.6
Seto, H.7
-
51
-
-
35748970471
-
Toward Mycobacterium tuberculosis DXR inhibitor design: homology modeling and molecular dynamics simulations
-
Singh, N., Avery, M.A. and McCurdy, C.R. (2007) Toward Mycobacterium tuberculosis DXR inhibitor design: homology modeling and molecular dynamics simulations. Journal of Computer-Aided Molecular Design, 21, 511-522.
-
(2007)
Journal of Computer-Aided Molecular Design
, vol.21
, pp. 511-522
-
-
Singh, N.1
Avery, M.A.2
McCurdy, C.R.3
-
52
-
-
33846020045
-
Isoprenoid biosynthesis of the apicoplast as drug target
-
Wiesner, J. and Jomaa, H. (2007) Isoprenoid biosynthesis of the apicoplast as drug target. Current Drug Targets, 8, 3-13.
-
(2007)
Current Drug Targets
, vol.8
, pp. 3-13
-
-
Wiesner, J.1
Jomaa, H.2
-
53
-
-
37349115214
-
Double ester prodrugs of FR900098 display enhanced in-vitro antimalarial activity
-
Wiesner, J., Ortmann, R., Jomaa, H. and Schlitzer, M. (2007) Double ester prodrugs of FR900098 display enhanced in-vitro antimalarial activity. Archiv der Pharmazie, 340, 661-666.
-
(2007)
Archiv der Pharmazie
, vol.340
, pp. 661-666
-
-
Wiesner, J.1
Ortmann, R.2
Jomaa, H.3
Schlitzer, M.4
-
54
-
-
34247215645
-
Advances in drug discovery and biochemical studies
-
Kita, K., Shiomi, K. and Omura, S. (2007) Advances in drug discovery and biochemical studies. Trends in Parasitology, 23, 223-229.
-
(2007)
Trends in Parasitology
, vol.23
, pp. 223-229
-
-
Kita, K.1
Shiomi, K.2
Omura, S.3
-
55
-
-
37849029476
-
Anaerobic NADH-fumarate reductase system is predominant in the respiratory chain of Echinococcus multilocularis, providing a novel target for the chemotherapy of alveolar echinococcosis
-
Matsumoto, J., Sakamoto, K., Shinjyo, N., Kido, Y., Yamamoto, N., Yagi, K., Miyoshi, H. et al. (2008) Anaerobic NADH-fumarate reductase system is predominant in the respiratory chain of Echinococcus multilocularis, providing a novel target for the chemotherapy of alveolar echinococcosis. Antimicrobial Agents and Chemotherapy, 52, 164-170.
-
(2008)
Antimicrobial Agents and Chemotherapy
, vol.52
, pp. 164-170
-
-
Matsumoto, J.1
Sakamoto, K.2
Shinjyo, N.3
Kido, Y.4
Yamamoto, N.5
Yagi, K.6
Miyoshi, H.7
-
56
-
-
0036593544
-
Novel animal-health drug targets from ligand-gated chloride channels
-
Raymond, V. and Sattelle, D.B. (2002) Novel animal-health drug targets from ligand-gated chloride channels. Nature Reviews. Drug Discovery, 1, 427-436.
-
(2002)
Nature Reviews. Drug Discovery
, vol.1
, pp. 427-436
-
-
Raymond, V.1
Sattelle, D.B.2
-
57
-
-
0035068456
-
The biochemical basis of anthelmintic action and resistance
-
Kohler, P. (2001) The biochemical basis of anthelmintic action and resistance. International Journal for Parasitology, 31, 336-345.
-
(2001)
International Journal for Parasitology
, vol.31
, pp. 336-345
-
-
Kohler, P.1
-
58
-
-
33645581386
-
Glutamate-gated chloride channels and the mode of action of the avermectin/milbemycin anthelmintics
-
Wolstenholme, A.J. and Rogers, A.T. (2005) Glutamate-gated chloride channels and the mode of action of the avermectin/milbemycin anthelmintics. Parasitology, 131, S85-S95.
-
(2005)
Parasitology
, vol.131
-
-
Wolstenholme, A.J.1
Rogers, A.T.2
-
59
-
-
3042639355
-
Fipronil is a potent open channel blocker of glutamate-activated chloride channels in cockroach neurons
-
Zhao, X., Yeh, J.Z., Salgado, V.L. and Narahashi, T. (2004) Fipronil is a potent open channel blocker of glutamate-activated chloride channels in cockroach neurons. The Journal of Pharmacology and Experimental Therapeutics, 310, 192-201.
-
(2004)
The Journal of Pharmacology and Experimental Therapeutics
, vol.310
, pp. 192-201
-
-
Zhao, X.1
Yeh, J.Z.2
Salgado, V.L.3
Narahashi, T.4
-
60
-
-
40749099893
-
A new class of anthelmintics effective against drug-resistant nematodes
-
Kaminsky, R., Ducray, P., Jung, M., Clover, R., Rufener, L., Bouvier, J., Schorderet Weber, S. et al. (2008) A new class of anthelmintics effective against drug-resistant nematodes. Nature, 452, 176-180.
-
(2008)
Nature
, vol.452
, pp. 176-180
-
-
Kaminsky, R.1
Ducray, P.2
Jung, M.3
Clover, R.4
Rufener, L.5
Bouvier, J.6
Schorderet Weber, S.7
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