Structure of 1-deoxy-D-xylulose 5-phosphate reductoisomerase in a quaternary complex with a magnesium ion, NADPH and the antimalarial drug fosmidomycin

Acta Crystallographica Section F: Structural Biology and Crystallization Communications

Volumn 63, Issue 6, 2007, Pages 466-470

  Yajima, Shunsuke ^a   Hara, Kodai ^a,c   Iino, Daisuke ^a   Sasaki, Yasuyuki ^a   Kuzuyama, Tomohisa ^b   Ohsawa, Kanju ^a   Seto, Haruo ^a  

^a TOKYO UNIVERSITY OF AGRICULTURE   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c YOKOHAMA CITY UNIVERSITY   (Japan)

Author keywords

Antimalarial drugs; Fosmidomycin; MEP pathway

Indexed keywords

1 DEOXY D XYLULOSE 5 PHOSPHATE REDUCTOISOMERASE; 1-DEOXY-D-XYLULOSE 5-PHOSPHATE REDUCTOISOMERASE; ANTIMALARIAL AGENT; DRUG DERIVATIVE; FOSFOMYCIN; FOSMIDOMYCIN; ISOMERASE; MAGNESIUM; MULTIENZYME COMPLEX; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; OXIDOREDUCTASE; UNCLASSIFIED DRUG;

ARTICLE; CHEMISTRY; METABOLISM; PROTEIN QUATERNARY STRUCTURE; X RAY CRYSTALLOGRAPHY;

ALDOSE-KETOSE ISOMERASES; ANTIMALARIALS; CRYSTALLOGRAPHY, X-RAY; FOSFOMYCIN; MAGNESIUM; MULTIENZYME COMPLEXES; NADP; OXIDOREDUCTASES; PROTEIN STRUCTURE, QUATERNARY;

ESCHERICHIA COLI;

EID: 34249940474     PISSN: 17443091     EISSN: 17443091     Source Type: Journal    
DOI: 10.1107/S1744309107024475     Document Type: Article

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