Plasmatic concentration of organochlorine lindane acts as metabolic disruptors in HepG2 liver cell line by inducing mitochondrial disorder

Toxicology and Applied Pharmacology

Volumn 272, Issue 2, 2013, Pages 325-334

  Benarbia, Mohammed el Amine ^a,b   Macherel, David ^a,c   Faure, Sébastien ^a,b   Jacques, Caroline ^a,b   Andriantsitohaina, Ramaroson ^a,b   Malthièry, Yves ^a,b  

^a LUNAM Universite   (France)

^b INSERM   (France)

^c Universite d'Angers   (France)

Author keywords

Energetic metabolism; Mitochondria; Nitric oxide; Organochlorine; OXPHOS

Indexed keywords

ADENOSINE TRIPHOSPHATE; LACTIC ACID; LINDANE; ORGANOCHLORINE DERIVATIVE;

ARTICLE; BIOGENESIS; CELL METABOLISM; CELL VIABILITY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENERGY METABOLISM; HUMAN; HUMAN CELL; LIVER CELL; LIVER CELL CARCINOMA; UPREGULATION;

ENERGETIC METABOLISM; MITOCHONDRIA; NITRIC OXIDE; ORGANOCHLORINE; OXPHOS;

CELL CULTURE TECHNIQUES; CELL RESPIRATION; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRON TRANSPORT CHAIN COMPLEX PROTEINS; ENERGY METABOLISM; ENVIRONMENTAL POLLUTANTS; HEP G2 CELLS; HUMANS; LINDANE; MITOCHONDRIA, LIVER; NITRIC OXIDE; SUPEROXIDES;

EID: 84883784695     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.06.006     Document Type: Article

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