Hepatic sequestration of chlordecone and hexafluoroacetone evaluated by pharmacokinetic modeling

Toxicology

Volumn 234, Issue 1-2, 2007, Pages 59-72

  Belfiore, Carol J ^a   Yang, Raymond S H ^a   Chubb, Laura S ^a   Lohitnavy, Manupat ^a   Lohitnavy, Ornrat S ^a   Andersen, Melvin E ^a  

^a Department of Environmental and Radiological Health Sciences   (United States)

Author keywords

Acetone; Chlordecone; Hexafluoroacetone; Kepone; Mirex; PBPK

Indexed keywords

ACETAL DERIVATIVE; ACETONE; CARBON; CARBONYL DERIVATIVE; CHLORDECONE; CHLORINE DERIVATIVE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HEXAFLUOROACETONE; KETONE DERIVATIVE; THIOL DERIVATIVE;

ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; COMPARATIVE STUDY; EVALUATION; EXCRETION; LIPOPHILICITY; LIVER; MALE; MODEL; NONHUMAN; PARTITION COEFFICIENT; PRIORITY JOURNAL; RAT; TISSUE DISTRIBUTION;

ACETONE; ADMINISTRATION, ORAL; ALGORITHMS; ANIMALS; CHLORDECONE; DRUG EVALUATION, PRECLINICAL; FEMALE; FLUOROCARBONS; HYDROPHOBICITY; INJECTIONS, INTRAVENOUS; INSECTICIDES; LIPID METABOLISM; LIVER; MACACA MULATTA; MALE; MIREX; MODELS, BIOLOGICAL; MOLECULAR CONFORMATION; RATS; RATS, SPRAGUE-DAWLEY; TISSUE DISTRIBUTION;

RATTUS;

EID: 34047152723     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2007.02.002     Document Type: Article

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