Molecular investigation of the effects of lindane in rat hepatocytes: Microarray and mechanistic studies

Food and Chemical Toxicology

Volumn 49, Issue 12, 2011, Pages 3128-3135

  Zucchini Pascal, Nathalie ^a   de Sousa, Georges ^a   Pizzol, Jérôme ^a   Rahmani, Roger ^a  

^a TOXALIM RESEARCH CENTRE IN FOOD TOXICOLOGY   (France)

Author keywords

Apoptosis; Hepatocytes; Lindane; Oxidative stress; PKC; Toxicology

Indexed keywords

CASPASE; CYTOCHROME P450 3A4; CYTOCHROME P450 4A1; GLUTATHIONE TRANSFERASE A2; GUANINE NUCLEOTIDE EXCHANGE FACTOR; INITIATION FACTOR; LINDANE; PROTEIN BAX; PROTEIN BCL XL; PROTEIN EIF2B3; PROTEIN EIF2B4; PROTEIN KINASE C; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; DETOXIFICATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; GENE IDENTIFICATION; INTOXICATION; LIVER CELL; MALE; MICROARRAY ANALYSIS; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATION REDUCTION STATE; OXIDATIVE STRESS; RAT; SIGNAL TRANSDUCTION;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CASPASES; CELL DEATH; CYCLIC N-OXIDES; DOWN-REGULATION; HEPATOCYTES; INDOLES; LINDANE; MALE; NECROSIS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OXIDATIVE STRESS; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; UP-REGULATION;

RATTUS;

EID: 80054867741     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2011.09.033     Document Type: Article

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