Electron microscopic analysis of a spherical mitochondrial structure

Journal of Biological Chemistry

Volumn 287, Issue 50, 2012, Pages 42373-42378

  Ding, Wen Xing ^a   Li, Min ^b   Biazik, Joanna M ^c   Morgan, David G ^d   Guo, Fengli ^e   Ni, Hong Min ^a   Goheen, Michael ^b   Eskelinen, Eeva Liisa ^c   Yin, Xiao Ming ^b  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF HELSINKI   (Finland)

^d INDIANA UNIVERSITY   (United States)

^e STOWERS INSTITUTE FOR MEDICAL RESEARCH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

C-SHAPED; CYTOSOLIC; INNER MEMBRANES; MEMBRANE TOPOLOGY; MICROSCOPIC ANALYSIS; MITOCHONDRIAL DAMAGE; MURINE EMBRYONIC FIBROBLASTS; OUTER MEMBRANE; SERIAL SECTION; STRUCTURAL ALTERATIONS; STRUCTURAL FEATURE; TOMOGRAPHIC RECONSTRUCTION; TRANSMISSION ELECTRON; UNCOUPLERS;

CELL CULTURE; CYANIDES; MEMBRANES; MICROSCOPIC EXAMINATION;

MITOCHONDRIA;

CARBONYL CYANIDE CHLOROPHENYLHYDRAZONE;

ANIMAL TISSUE; ARTICLE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; EMBRYO; EXTRACELLULAR MATRIX; IMMUNOELECTRON MICROSCOPY; MEMBRANE STRUCTURE; MITOCHONDRIAL MEMBRANE; MITOPHAGY; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION UNCOUPLING; OXIDATIVE STRESS; PRIORITY JOURNAL; SPHEROID CELL; STRUCTURE ANALYSIS;

ANIMALS; CARBONYL CYANIDE M-CHLOROPHENYL HYDRAZONE; ELECTRON MICROSCOPE TOMOGRAPHY; EMBRYO, MAMMALIAN; FIBROBLASTS; MICE; MITOCHONDRIA; MITOCHONDRIAL DYNAMICS; PROTON IONOPHORES;

MURINAE;

EID: 84871305945     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M112.413674     Document Type: Article

References (27)

1. Scheffler, I. E. (1999) in Mitochondria (Scheffler, I. E., ed) pp. 15-47, Wiley-Liss, New York
2. Westermann, B. (2010) Mitochondrial fusion and fission in cell life and death. Nat. Rev. Mol. Cell Biol. 11, 872-884
3. Chan, D. C. (2006) Mitochondria: dynamic organelles in disease, aging, and development. Cell 125, 1241-1252
4. Wallace, D. C., Fan, W., and Procaccio, V. (2010) Mitochondrial energetics and therapeutics. Annu. Rev. Pathol. 5, 297-348
5. Lemasters, J. J. (2005) Selective mitochondrial autophagy, or mitophagy, as a targeted defense against oxidative stress, mitochondrial dysfunction, and aging. Rejuvenation Res. 8, 3-5
6. Green, D. R., Galluzzi, L., and Kroemer, G. (2011) Mitochondria and the autophagy-inflammation-cell death axis in organismal aging. Science 333, 1109-1112
7. Youle, R. J., and Narendra, D. P. (2011) Mechanisms of mitophagy. Nat. Rev. Mol. Cell. Biol. 12, 9-14
8. Ricci, J. E., Waterhouse, N., and Green, D. R. (2003) Mitochondrial functions during cell death, a complex (I-V) dilemma. Cell Death Differ. 10, 488-492 (Pubitemid 36656637)
9. Mastronarde, D. N. (2005) Automated electron microscope tomography using robust prediction of specimen movements. J. Struct. Biol. 152, 36-51
10. Kremer, J. R., Mastronarde, D. N., and McIntosh, J. R. (1996) Computer visualization of three-dimensional image data using IMOD. J. Struct. Biol. 116, 71-76 (Pubitemid 26093126)
11. Narendra, D., Tanaka, A., Suen, D. F., and Youle, R. J. (2008) Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J. Cell Biol. 183, 795-803
12. Geisler, S., Holmström, K. M., Skujat, D., Fiesel, F. C., Rothfuss, O. C., Kahle, P. J., and Springer, W. (2010) PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat. Cell Biol. 12, 119-131
13. Ding, W. X., Ni, H. M., Li, M., Liao, Y., Chen, X., Stolz, D. B., Dorn, G. W., 2nd, and Yin, X. M. (2010) Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin- ubiquitin-p62-mediated mitochondrial priming. J. Biol. Chem. 285, 27879-27890
14. Matsuda, N., Sato, S., Shiba, K., Okatsu, K., Saisho, K., Gautier, C. A., Sou, Y. S., Saiki, S., Kawajiri, S., Sato, F., Kimura, M., Komatsu, M., Hattori, N., and Tanaka, K. (2010) PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy. J. Cell Biol. 189, 211-221
15. Lee, J. Y., Nagano, Y., Taylor, J. P., Lim, K. L., and Yao, T. P. (2010) Diseasecausing mutations in Parkin impair mitochondrial ubiquitination, aggregation, and HDAC6-dependent mitophagy. J. Cell Biol. 189, 671-679
16. Chan, N. C., Salazar, A. M., Pham, A. H., Sweredoski, M. J., Kolawa, N. J., Graham, R. L., Hess, S., and Chan, D. C. (2011) Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy. Hum. Mol. Genet. 20, 1726-1737
17. Yoshii, S. R., Kishi, C., Ishihara, N., and Mizushima, N. (2011) Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane. J. Biol. Chem. 286, 19630-19640
18. Messerschmitt, M., Jakobs, S., Vogel, F., Fritz, S., Dimmer, K. S., Neupert, W., and Westermann, B. (2003) The inner membrane protein Mdm33 controls mitochondrial morphology in yeast. J. Cell Biol. 160, 553-564 (Pubitemid 36254393)
19. Benard, G., Bellance, N., James, D., Parrone, P., Fernandez, H., Letellier, T., and Rossignol, R. (2007) Mitochondrial bioenergetics and structural network organization. J. Cell Sci. 120, 838-848 (Pubitemid 46523485)
20. Cui, M., Tang, X., Christian, W. V., Yoon, Y., and Tieu, K. (2010) Perturbations in mitochondrial dynamics induced by human mutant PINK1 can be rescued by the mitochondrial division inhibitor mdivi-1. J. Biol. Chem. 285, 11740-11752
21. Liu, X., and Hajnóczky, G. (2011) Altered fusion dynamics underlie unique morphological changes in mitochondria during hypoxia-reoxygenation stress. Cell Death Differ. 18, 1561-1572
22. Christensen, A. K., and Chapman, G. B. (1959) Cup-shaped mitochondria in interstitial cells of the albino rat testis. Exp. Cell Res. 18, 576-579
23. Kiessling, K. H., and Tobe, U. (1964) Degeneration of liver mitochondria in rats after prolonged alcohol consumption. Exp. Cell Res. 33, 350-354
24. Stephens, R. J., and Bils, R. F. (1965) An atypical mitochondrial form in normal rat liver. J. Cell Biol. 24, 500-504
25. Setoguti, T. (1977) Electron microscopic studies of the parathyroid gland of senile dogs. Am. J. Anat. 148, 65-83
26. Lauber, J. K. (1982) Retinal pigment epithelium: ring mitochondria and lesions induced by continuous light. Curr. Eye Res. 2, 855-862
27. Ding, W. X., Guo, F., Ni, H. M., Bockus, A., Manley, S., Stolz, D. B., Eskelinen, E. L., Jaeschke, H., and Yin, X. M. (October 24, 2012) Parkin and mitofusins reciprocally regulate mitophagy and mitochondrial spheroid formation. J. Biol. Chem. 287, 42379-42388