Zonation of cytochrome P450 expression, drug metabolism and toxicity in liver

General Pharmacology

Volumn 28, Issue 2, 1997, Pages 191-196

  Lindros, Kai O ^a  

^a NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

cytochrome P450; drug toxicity; glutathione conjugation; growth hormone; liver zonation

Indexed keywords

ANTIOXIDANT; CYTOCHROME P450 ISOENZYME; DEXAMETHASONE; GLUCURONOSYLTRANSFERASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; GROWTH HORMONE; PARACETAMOL; PHENOBARBITAL;

DRUG METABOLISM; ENDOCRINE SYSTEM; ENZYME INDUCTION; GENE EXPRESSION; LIVER METABOLISM; LIVER TOXICITY; LIVER VEIN; NONHUMAN; PORTAL VEIN; PRIORITY JOURNAL; REGULATORY MECHANISM; REVIEW; TISSUE DISTRIBUTION;

ANIMALS; BIOTRANSFORMATION; CYTOCHROME P-450 CYP2E1; CYTOCHROME P-450 ENZYME SYSTEM; DRUG TOXICITY; ENZYME INDUCTION; ISOENZYMES; LIVER; PITUITARY HORMONES;

EID: 0031012845     PISSN: 03063623     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-3623(96)00183-8     Document Type: Review

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