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Volumn 12, Issue 17, 2013, Pages 2738-2743

The role of cyclin D1 in response to longterm exposure to ionizing radiation

Author keywords

AKT; Cyclin D1; Double strand breaks; Long term fractionated radiation; Radioprotection

Indexed keywords

CYCLIN D1; F BOX PROTEIN; F BOX PROTEIN 31; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; UNCLASSIFIED DRUG;

EID: 84883590255     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.25746     Document Type: Review
Times cited : (32)

References (65)
  • 1
    • 0021682817 scopus 로고
    • Repair processes in radiation biology
    • PMID:6390488
    • Elkind MM. Repair processes in radiation biology. Radiat Res 1984; 100:425-49; PMID:6390488; http://dx.doi.org/10.2307/3576409
    • (1984) Radiat Res , vol.100 , pp. 425-449
    • Elkind, M.M.1
  • 2
    • 78649336706 scopus 로고    scopus 로고
    • The DNA damage response: Making it safe to play with knives
    • PMID:20965415
    • Ciccia A, Elledge SJ. The DNA damage response: making it safe to play with knives. Mol Cell 2010; 40:179-204; PMID:20965415; http://dx.doi.org/10. 1016/j.molcel.2010.09.019
    • (2010) Mol Cell , vol.40 , pp. 179-204
    • Ciccia, A.1    Elledge, S.J.2
  • 3
    • 0034616913 scopus 로고    scopus 로고
    • Distinct initiation and maintenance mechanisms cooperate to induce G1 cell cycle arrest in response to DNA damage
    • PMID:10929713
    • Agami R, Bernards R. Distinct initiation and maintenance mechanisms cooperate to induce G1 cell cycle arrest in response to DNA damage. Cell 2000; 102:55-66; PMID:10929713; http://dx.doi.org/10.1016/S0092-8674(00)00010-6
    • (2000) Cell , vol.102 , pp. 55-66
    • Agami, R.1    Bernards, R.2
  • 4
    • 38849129888 scopus 로고    scopus 로고
    • Regulation of the cellular DNA double-strand break response
    • PMID:18059525
    • Cann KL, Hicks GG. Regulation of the cellular DNA double-strand break response. Biochem Cell Biol 2007; 85:663-74; PMID:18059525; http://dx.doi.org/ 10.1139/O07-135
    • (2007) Biochem Cell Biol , vol.85 , pp. 663-674
    • Cann, K.L.1    Hicks, G.G.2
  • 5
    • 36749022214 scopus 로고    scopus 로고
    • The DNA damage response: Ten years after
    • PMID:18082599
    • Harper JW, Elledge SJ. The DNA damage response: ten years after. Mol Cell 2007; 28:739-45; PMID:18082599; http://dx.doi.org/10.1016/j.molcel.2007.11.015
    • (2007) Mol Cell , vol.28 , pp. 739-745
    • Harper, J.W.1    Elledge, S.J.2
  • 6
    • 0033552595 scopus 로고    scopus 로고
    • Regulation of p53 in response to DNA damage
    • PMID:10618704
    • Lakin ND, Jackson SP. Regulation of p53 in response to DNA damage. Oncogene 1999; 18:7644-55; PMID:10618704; http://dx.doi.org/10.1038/sj.onc. 1203015
    • (1999) Oncogene , vol.18 , pp. 7644-7655
    • Lakin, N.D.1    Jackson, S.P.2
  • 7
    • 0345826544 scopus 로고    scopus 로고
    • Molecular mechanisms of irradiation-induced apoptosis
    • PMID:12456331
    • Zhou L, Yuan R, Serggio L. Molecular mechanisms of irradiation-induced apoptosis. Front Biosci 2003; 8:d9-19; PMID:12456331; http://dx.doi.org/10.2741/ 927
    • (2003) Front Biosci , vol.8
    • Zhou, L.1    Yuan, R.2    Serggio, L.3
  • 8
    • 34250308322 scopus 로고    scopus 로고
    • Apoptosis: A review of programmed cell death
    • PMID:17562483
    • Elmore S. Apoptosis: a review of programmed cell death. Toxicol Pathol 2007; 35:495-516; PMID:17562483; http://dx.doi.org/10.1080/01926230701320337
    • (2007) Toxicol Pathol , vol.35 , pp. 495-516
    • Elmore, S.1
  • 9
    • 77956173218 scopus 로고    scopus 로고
    • Acquired radioresistance of human tumor cells by DNA-PK/AKT/GSK3beta- mediated cyclin D1 overexpression
    • PMID:20562919
    • Shimura T, Kakuda S, Ochiai Y, Nakagawa H, Kuwahara Y, Takai Y, Kobayashi J, Komatsu K, Fukumoto M. Acquired radioresistance of human tumor cells by DNA-PK/AKT/GSK3beta-mediated cyclin D1 overexpression. Oncogene 2010; 29:4826-37; PMID:20562919; http://dx.doi.org/10.1038/onc.2010.238
    • (2010) Oncogene , vol.29 , pp. 4826-4837
    • Shimura, T.1    Kakuda, S.2    Ochiai, Y.3    Nakagawa, H.4    Kuwahara, Y.5    Takai, Y.6    Kobayashi, J.7    Komatsu, K.8    Fukumoto, M.9
  • 10
    • 80053369101 scopus 로고    scopus 로고
    • Acquired radioresistance of cancer and the AKT/GSK3β/cyclin D1 overexpression cycle
    • PMID:21881296
    • Shimura T. Acquired radioresistance of cancer and the AKT/GSK3β/cyclin D1 overexpression cycle. J Radiat Res 2011; 52:539-44; PMID:21881296; http://dx.doi.org/10.1269/jrr.11098
    • (2011) J Radiat Res , vol.52 , pp. 539-544
    • Shimura, T.1
  • 11
    • 0032533225 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization
    • PMID:9832503
    • Diehl JA, Cheng M, Roussel MF, Sherr CJ. Glycogen synthase kinase-3beta regulates cyclin D1 proteolysis and subcellular localization. Genes Dev 1998; 12:3499-511; PMID:9832503; http://dx.doi.org/10.1101/gad.12.22.3499
    • (1998) Genes Dev , vol.12 , pp. 3499-3511
    • Diehl, J.A.1    Cheng, M.2    Roussel, M.F.3    Sherr, C.J.4
  • 12
    • 0036632368 scopus 로고    scopus 로고
    • The phosphatidylinositol 3-Kinase AKT pathway in human cancer
    • PMID:12094235
    • Vivanco I, Sawyers CL. The phosphatidylinositol 3-Kinase AKT pathway in human cancer. Nat Rev Cancer 2002; 2:489-501; PMID:12094235; http://dx.doi.org/10.1038/nrc839
    • (2002) Nat Rev Cancer , vol.2 , pp. 489-501
    • Vivanco, I.1    Sawyers, C.L.2
  • 13
    • 34250788809 scopus 로고    scopus 로고
    • AKT/PKB signaling: Navigating downstream
    • PMID:17604717
    • Manning BD, Cantley LC. AKT/PKB signaling: navigating downstream. Cell 2007; 129:1261-74; PMID:17604717; http://dx.doi.org/10.1016/j.cell.2007.06.009
    • (2007) Cell , vol.129 , pp. 1261-1274
    • Manning, B.D.1    Cantley, L.C.2
  • 15
    • 0036185848 scopus 로고    scopus 로고
    • The protein kinase B/Akt signalling pathway in human malignancy
    • PMID:11882383
    • Nicholson KM, Anderson NG. The protein kinase B/Akt signalling pathway in human malignancy. Cell Signal 2002; 14:381-95; PMID:11882383; http://dx.doi.org/10.1016/S0898-6568(01)00271-6
    • (2002) Cell Signal , vol.14 , pp. 381-395
    • Nicholson, K.M.1    Anderson, N.G.2
  • 16
    • 0034671768 scopus 로고    scopus 로고
    • Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation
    • PMID:11124803
    • Alt JR, Cleveland JL, Hannink M, Diehl JA. Phosphorylation-dependent regulation of cyclin D1 nuclear export and cyclin D1-dependent cellular transformation. Genes Dev 2000; 14:3102-14; PMID:11124803; http://dx.doi.org/10. 1101/gad.854900
    • (2000) Genes Dev , vol.14 , pp. 3102-3114
    • Alt, J.R.1    Cleveland, J.L.2    Hannink, M.3    Diehl, J.A.4
  • 17
    • 9244239811 scopus 로고    scopus 로고
    • G1 cell-cycle control and cancer
    • PMID:15549091
    • Massagué J. G1 cell-cycle control and cancer. Nature 2004; 432:298-306; PMID:15549091; http://dx.doi.org/10.1038/nature03094
    • (2004) Nature , vol.432 , pp. 298-306
    • Massagué, J.1
  • 18
    • 0028179669 scopus 로고
    • P27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest
    • PMID:8288131
    • Polyak K, Kato JY, Solomon MJ, Sherr CJ, Massague J, Roberts JM, Koff A. p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest. Genes Dev 1994; 8:9-22; PMID:8288131; http://dx.doi.org/10.1101/gad.8.1.9
    • (1994) Genes Dev , vol.8 , pp. 9-22
    • Polyak, K.1    Kato, J.Y.2    Solomon, M.J.3    Sherr, C.J.4    Massague, J.5    Roberts, J.M.6    Koff, A.7
  • 19
    • 0033564697 scopus 로고    scopus 로고
    • CDK inhibitors: Positive and negative regulators of G1-phase progression
    • PMID:10385618
    • Sherr CJ, Roberts JM. CDK inhibitors: positive and negative regulators of G1-phase progression. Genes Dev 1999; 13:1501-12; PMID:10385618; http://dx.doi.org/10.1101/gad.13.12.1501
    • (1999) Genes Dev , vol.13 , pp. 1501-1512
    • Sherr, C.J.1    Roberts, J.M.2
  • 20
    • 33749524648 scopus 로고    scopus 로고
    • Glycogen synthase kinase 3 has a limited role in cell cycle regulation of cyclin D1 levels
    • PMID:16942622
    • Yang K, Guo Y, Stacey WC, Harwalkar J, Fretthold J, Hitomi M, Stacey DW. Glycogen synthase kinase 3 has a limited role in cell cycle regulation of cyclin D1 levels. BMC Cell Biol 2006; 7:33; PMID:16942622; http://dx.doi.org/10.1186/ 1471-2121-7-33
    • (2006) BMC Cell Biol , vol.7 , pp. 33
    • Yang, K.1    Guo, Y.2    Stacey, W.C.3    Harwalkar, J.4    Fretthold, J.5    Hitomi, M.6    Stacey, D.W.7
  • 21
    • 36248975284 scopus 로고    scopus 로고
    • Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication
    • PMID:18006686
    • Aggarwal P, Lessie MD, Lin DI, Pontano L, Gladden AB, Nuskey B, Goradia A, Wasik MA, Klein-Szanto AJ, Rustgi AK, et al. Nuclear accumulation of cyclin D1 during S phase inhibits Cul4-dependent Cdt1 proteolysis and triggers p53-dependent DNA rereplication. Genes Dev 2007; 21:2908-22; PMID:18006686; http://dx.doi.org/10.1101/gad.1586007
    • (2007) Genes Dev , vol.21 , pp. 2908-2922
    • Aggarwal, P.1    Lessie, M.D.2    Lin, D.I.3    Pontano, L.4    Gladden, A.B.5    Nuskey, B.6    Goradia, A.7    Wasik, M.A.8    Klein-Szanto, A.J.9    Rustgi, A.K.10
  • 22
    • 84874603109 scopus 로고    scopus 로고
    • Cyclin D1 overexpression perturbs DNA replication and induces replication-associated DNA double-strand breaks in acquired radioresistant cells
    • PMID:23388457
    • Shimura T, Ochiai Y, Noma N, Oikawa T, Sano Y, Fukumoto M. Cyclin D1 overexpression perturbs DNA replication and induces replication-associated DNA double-strand breaks in acquired radioresistant cells. Cell Cycle 2013; 12:773-82; PMID:23388457; http://dx.doi.org/10.4161/cc.23719
    • (2013) Cell Cycle , vol.12 , pp. 773-782
    • Shimura, T.1    Ochiai, Y.2    Noma, N.3    Oikawa, T.4    Sano, Y.5    Fukumoto, M.6
  • 23
    • 66649117243 scopus 로고    scopus 로고
    • F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage
    • PMID:19412162
    • Santra MK, Wajapeyee N, Green MR. F-box protein FBXO31 mediates cyclin D1 degradation to induce G1 arrest after DNA damage. Nature 2009; 459:722-5; PMID:19412162; http://dx.doi.org/10.1038/nature08011
    • (2009) Nature , vol.459 , pp. 722-725
    • Santra, M.K.1    Wajapeyee, N.2    Green, M.R.3
  • 25
    • 33644557709 scopus 로고    scopus 로고
    • Protein kinase B/Akt-dependent phosphorylation of glycogen synthase kinase-3beta in irradiated vascular endothelium
    • PMID:16489037
    • Tan J, Geng L, Yazlovitskaya EM, Hallahan DE. Protein kinase B/Akt-dependent phosphorylation of glycogen synthase kinase-3beta in irradiated vascular endothelium. Cancer Res 2006; 66:2320-7; PMID:16489037; http://dx.doi.org/10.1158/0008-5472.CAN-05-2700
    • (2006) Cancer Res , vol.66 , pp. 2320-2327
    • Tan, J.1    Geng, L.2    Yazlovitskaya, E.M.3    Hallahan, D.E.4
  • 26
    • 80655149127 scopus 로고    scopus 로고
    • DNA double-strand break-induced pro-survival signaling
    • PMID:21726915
    • Hawkins AJ, Golding SE, Khalil A, Valerie K. DNA double-strand break-induced pro-survival signaling. Radiother Oncol 2011; 101:13-7; PMID:21726915; http://dx.doi.org/10.1016/j.radonc.2011.05.074
    • (2011) Radiother Oncol , vol.101 , pp. 13-17
    • Hawkins, A.J.1    Golding, S.E.2    Khalil, A.3    Valerie, K.4
  • 27
    • 42949165854 scopus 로고    scopus 로고
    • PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survival
    • PMID:18439899
    • Bozulic L, Surucu B, Hynx D, Hemmings BA. PKBalpha/Akt1 acts downstream of DNA-PK in the DNA double-strand break response and promotes survival. Mol Cell 2008; 30:203-13; PMID:18439899; http://dx.doi.org/10.1016/j.molcel.2008.02. 024
    • (2008) Mol Cell , vol.30 , pp. 203-213
    • Bozulic, L.1    Surucu, B.2    Hynx, D.3    Hemmings, B.A.4
  • 28
    • 0033080511 scopus 로고    scopus 로고
    • Cyclin D1 inhibits cell proliferation through binding to PCNA and cdk2
    • PMID:9925749
    • Fukami-Kobayashi J, Mitsui Y. Cyclin D1 inhibits cell proliferation through binding to PCNA and cdk2. Exp Cell Res 1999; 246:338-47; PMID:9925749; http://dx.doi.org/10.1006/excr.1998.4306
    • (1999) Exp Cell Res , vol.246 , pp. 338-347
    • Fukami-Kobayashi, J.1    Mitsui, Y.2
  • 29
    • 0027946715 scopus 로고
    • Proliferating cell nuclear antigen bound to DNA synthesis sites: Phosphorylation and association with cyclin D1 and cyclin A
    • PMID:7982468
    • Prosperi E, Scovassi AI, Stivala LA, Bianchi L. Proliferating cell nuclear antigen bound to DNA synthesis sites: phosphorylation and association with cyclin D1 and cyclin A. Exp Cell Res 1994; 215:257-62; PMID:7982468; http://dx.doi.org/10.1006/excr.1994.1341
    • (1994) Exp Cell Res , vol.215 , pp. 257-262
    • Prosperi, E.1    Scovassi, A.I.2    Stivala, L.A.3    Bianchi, L.4
  • 30
    • 0026459047 scopus 로고
    • D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA
    • PMID:1358458
    • Xiong Y, Zhang H, Beach D. D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA. Cell 1992; 71:505-14; PMID:1358458; http://dx.doi.org/10.1016/0092-8674(92)90518-H
    • (1992) Cell , vol.71 , pp. 505-514
    • Xiong, Y.1    Zhang, H.2    Beach, D.3
  • 31
    • 37349039649 scopus 로고    scopus 로고
    • Bloom's syndrome helicase and Mus81 are required to induce transient double-strand DNA breaks in response to DNA replication stress
    • PMID:18054789
    • Shimura T, Torres MJ, Martin MM, Rao VA, Pommier Y, Katsura M, Miyagawa K, Aladjem MI. Bloom's syndrome helicase and Mus81 are required to induce transient double-strand DNA breaks in response to DNA replication stress. J Mol Biol 2008; 375:1152-64; PMID:18054789; http://dx.doi.org/10.1016/j.jmb.2007.11. 006
    • (2008) J Mol Biol , vol.375 , pp. 1152-1164
    • Shimura, T.1    Torres, M.J.2    Martin, M.M.3    Rao, V.A.4    Pommier, Y.5    Katsura, M.6    Miyagawa, K.7    Aladjem, M.I.8
  • 32
    • 74849102185 scopus 로고    scopus 로고
    • Cyclin A overexpression induces chromosomal double-strand breaks in mammalian cells
    • PMID:19901524
    • Tane S, Chibazakura T. Cyclin A overexpression induces chromosomal double-strand breaks in mammalian cells. Cell Cycle 2009; 8:3900-3; PMID:19901524; http://dx.doi.org/10.4161/cc.8.23.10071
    • (2009) Cell Cycle , vol.8 , pp. 3900-3903
    • Tane, S.1    Chibazakura, T.2
  • 34
    • 77956208698 scopus 로고    scopus 로고
    • In vivo formation of gamma-H2AX and 53BP1 DNA repair foci in blood cells after radioiodine therapy of differentiated thyroid cancer
    • PMID:20660387
    • Lassmann M, Hänscheid H, Gassen D, Biko J, Meineke V, Reiners C, Scherthan H. In vivo formation of gamma-H2AX and 53BP1 DNA repair foci in blood cells after radioiodine therapy of differentiated thyroid cancer. J Nucl Med 2010; 51:1318-25; PMID:20660387; http://dx.doi.org/10.2967/jnumed.109.071357
    • (2010) J Nucl Med , vol.51 , pp. 1318-1325
    • Lassmann, M.1    Hänscheid, H.2    Gassen, D.3    Biko, J.4    Meineke, V.5    Reiners, C.6    Scherthan, H.7
  • 35
    • 0028331092 scopus 로고
    • Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining
    • PMID:8137296
    • Gillett C, Fantl V, Smith R, Fisher C, Bartek J, Dickson C, Barnes D, Peters G. Amplification and overexpression of cyclin D1 in breast cancer detected by immunohistochemical staining. Cancer Res 1994; 54:1812-7; PMID:8137296
    • (1994) Cancer Res , vol.54 , pp. 1812-1817
    • Gillett, C.1    Fantl, V.2    Smith, R.3    Fisher, C.4    Bartek, J.5    Dickson, C.6    Barnes, D.7    Peters, G.8
  • 36
    • 0033580462 scopus 로고    scopus 로고
    • Cyclin D1 and D3 associate with the SCF complex and are coordinately elevated in breast cancer
    • PMID:10208420
    • Russell A, Thompson MA, Hendley J, Trute L, Armes J, Germain D. Cyclin D1 and D3 associate with the SCF complex and are coordinately elevated in breast cancer. Oncogene 1999; 18:1983-91; PMID:10208420; http://dx.doi.org/10.1038/sj. onc.1202511
    • (1999) Oncogene , vol.18 , pp. 1983-1991
    • Russell, A.1    Thompson, M.A.2    Hendley, J.3    Trute, L.4    Armes, J.5    Germain, D.6
  • 37
    • 0013439945 scopus 로고    scopus 로고
    • Cycling to cancer with cyclin D1
    • PMID:12432268
    • Diehl JA. Cycling to cancer with cyclin D1. Cancer Biol Ther 2002; 1:226-31; PMID:12432268
    • (2002) Cancer Biol Ther , vol.1 , pp. 226-231
    • Diehl, J.A.1
  • 38
    • 20444439929 scopus 로고    scopus 로고
    • Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitment
    • PMID:15713663
    • Fu M, Rao M, Bouras T, Wang C, Wu K, Zhang X, Li Z, Yao TP, Pestell RG. Cyclin D1 inhibits peroxisome proliferator-activated receptor gamma-mediated adipogenesis through histone deacetylase recruitment. J Biol Chem 2005; 280:16934-41; PMID:15713663; http://dx.doi.org/10.1074/jbc.M500403200
    • (2005) J Biol Chem , vol.280 , pp. 16934-16941
    • Fu, M.1    Rao, M.2    Bouras, T.3    Wang, C.4    Wu, K.5    Zhang, X.6    Li, Z.7    Yao, T.P.8    Pestell, R.G.9
  • 39
    • 4344689970 scopus 로고    scopus 로고
    • Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice
    • PMID:15314168
    • Hulit J, Wang C, Li Z, Albanese C, Rao M, Di Vizio D, Shah S, Byers SW, Mahmood R, Augenlicht LH, et al. Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice. Mol Cell Biol 2004; 24:7598-611; PMID:15314168; http://dx.doi.org/10.1128/MCB.24.17. 7598-7611.2004
    • (2004) Mol Cell Biol , vol.24 , pp. 7598-7611
    • Hulit, J.1    Wang, C.2    Li, Z.3    Albanese, C.4    Rao, M.5    Di Vizio, D.6    Shah, S.7    Byers, S.W.8    Mahmood, R.9    Augenlicht, L.H.10
  • 40
    • 84865690685 scopus 로고    scopus 로고
    • Cyclin d1 induces chromosomal instability
    • PMID:22538871
    • Casimiro MC, Pestell RG. Cyclin d1 induces chromosomal instability. Oncotarget 2012; 3:224-5; PMID:22538871
    • (2012) Oncotarget , vol.3 , pp. 224-225
    • Casimiro, M.C.1    Pestell, R.G.2
  • 41
    • 0036107422 scopus 로고    scopus 로고
    • Aberrant expression of cell-cycle regulator cyclin D1 in breast cancer is related to chromosomal genomic instability
    • PMID:12007188
    • Lung JC, Chu JS, Yu JC, Yue CT, Lo YL, Shen CY, Wu CW. Aberrant expression of cell-cycle regulator cyclin D1 in breast cancer is related to chromosomal genomic instability. Genes Chromosomes Cancer 2002; 34:276-84; PMID:12007188; http://dx.doi.org/10.1002/gcc.10072
    • (2002) Genes Chromosomes Cancer , vol.34 , pp. 276-284
    • Lung, J.C.1    Chu, J.S.2    Yu, J.C.3    Yue, C.T.4    Lo, Y.L.5    Shen, C.Y.6    Wu, C.W.7
  • 42
    • 0027293137 scopus 로고
    • Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts
    • PMID:8339933
    • Quelle DE, Ashmun RA, Shurtleff SA, Kato JY, Bar-Sagi D, Roussel MF, Sherr CJ. Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts. Genes Dev 1993; 7:1559-71; PMID:8339933; http://dx.doi.org/10.1101/ gad.7.8.1559
    • (1993) Genes Dev , vol.7 , pp. 1559-1571
    • Quelle, D.E.1    Ashmun, R.A.2    Shurtleff, S.A.3    Kato, J.Y.4    Bar-Sagi, D.5    Roussel, M.F.6    Sherr, C.J.7
  • 43
    • 33749863640 scopus 로고    scopus 로고
    • Identification of mutations that disrupt phosphorylation-dependent nuclear export of cyclin D1
    • PMID:16732330
    • Benzeno S, Lu F, Guo M, Barbash O, Zhang F, Herman JG, Klein PS, Rustgi A, Diehl JA. Identification of mutations that disrupt phosphorylation-dependent nuclear export of cyclin D1. Oncogene 2006; 25:6291-303; PMID:16732330; http://dx.doi.org/10.1038/sj.onc.1209644
    • (2006) Oncogene , vol.25 , pp. 6291-6303
    • Benzeno, S.1    Lu, F.2    Guo, M.3    Barbash, O.4    Zhang, F.5    Herman, J.G.6    Klein, P.S.7    Rustgi, A.8    Diehl, J.A.9
  • 44
    • 28044464730 scopus 로고    scopus 로고
    • Location, location, location: The role of cyclin D1 nuclear localization in cancer
    • PMID:16163738
    • Gladden AB, Diehl JA. Location, location, location: the role of cyclin D1 nuclear localization in cancer. J Cell Biochem 2005; 96:906-13; PMID:16163738; http://dx.doi.org/10.1002/jcb.20613
    • (2005) J Cell Biochem , vol.96 , pp. 906-913
    • Gladden, A.B.1    Diehl, J.A.2
  • 45
    • 39749200927 scopus 로고    scopus 로고
    • Disruption of cyclin D1 nuclear export and proteolysis accelerates mammary carcinogenesis
    • PMID:17724472
    • Lin DI, Lessie MD, Gladden AB, Bassing CH, Wagner KU, Diehl JA. Disruption of cyclin D1 nuclear export and proteolysis accelerates mammary carcinogenesis. Oncogene 2008; 27:1231-42; PMID:17724472; http://dx.doi.org/10. 1038/sj.onc.1210738
    • (2008) Oncogene , vol.27 , pp. 1231-1242
    • Lin, D.I.1    Lessie, M.D.2    Gladden, A.B.3    Bassing, C.H.4    Wagner, K.U.5    Diehl, J.A.6
  • 46
    • 33846128155 scopus 로고    scopus 로고
    • The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence
    • PMID:17210786
    • Mallette FA, Gaumont-Leclerc MF, Ferbeyre G. The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence. Genes Dev 2007; 21:43-8; PMID:17210786; http://dx.doi.org/10.1101/gad.1487307
    • (2007) Genes Dev , vol.21 , pp. 43-48
    • Mallette, F.A.1    Gaumont-Leclerc, M.F.2    Ferbeyre, G.3
  • 49
    • 84873412967 scopus 로고    scopus 로고
    • The WRN and MUS81 proteins limit cell death and genome instability following oncogene activation
    • PMID:22410776
    • Murfuni I, Nicolai S, Baldari S, Crescenzi M, Bignami M, Franchitto A, et al. The WRN and MUS81 proteins limit cell death and genome instability following oncogene activation. Oncogene 2013; 32:610-20; PMID:22410776; http://dx.doi.org/10.1038/onc.2012.80
    • (2013) Oncogene , vol.32 , pp. 610-620
    • Murfuni, I.1    Nicolai, S.2    Baldari, S.3    Crescenzi, M.4    Bignami, M.5    Franchitto, A.6
  • 50
    • 0027332123 scopus 로고
    • Altered regulation of G1 cyclins in senescent human diploid fibroblasts: Accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes
    • PMID:8248208
    • Dulić V, Drullinger LF, Lees E, Reed SI, Stein GH. Altered regulation of G1 cyclins in senescent human diploid fibroblasts: accumulation of inactive cyclin E-Cdk2 and cyclin D1-Cdk2 complexes. Proc Natl Acad Sci U S A 1993; 90:11034-8; PMID:8248208; http://dx.doi.org/10.1073/pnas.90.23.11034
    • (1993) Proc Natl Acad Sci U S A , vol.90 , pp. 11034-11038
    • Dulić, V.1    Drullinger, L.F.2    Lees, E.3    Reed, S.I.4    Stein, G.H.5
  • 51
    • 0027269711 scopus 로고
    • Deregulation of cyclins D1 and e and suppression of cdk2 and cdk4 in senescent human fibroblasts
    • PMID:8360268
    • Lucibello FC, Sewing A, Brüsselbach S, Bürger C, Müller R. Deregulation of cyclins D1 and E and suppression of cdk2 and cdk4 in senescent human fibroblasts. J Cell Sci 1993; 105:123-33; PMID:8360268
    • (1993) J Cell Sci , vol.105 , pp. 123-133
    • Lucibello, F.C.1    Sewing, A.2    Brüsselbach, S.3    Bürger, C.4    Müller, R.5
  • 52
    • 0028943438 scopus 로고
    • Overexpression of cyclin D1 blocks proliferation of normal diploid fibroblasts
    • PMID:7698220
    • Atadja P, Wong H, Veillete C, Riabowol K. Overexpression of cyclin D1 blocks proliferation of normal diploid fibroblasts. Exp Cell Res 1995; 217:205-16; PMID:7698220; http://dx.doi.org/10.1006/excr.1995.1080
    • (1995) Exp Cell Res , vol.217 , pp. 205-216
    • Atadja, P.1    Wong, H.2    Veillete, C.3    Riabowol, K.4
  • 53
    • 84871503188 scopus 로고    scopus 로고
    • Hyper-mitogenic drive coexists with mitotic incompetence in senescent cells
    • PMID:23187803
    • Leontieva OV, Lenzo F, Demidenko ZN, Blagosklonny MV. Hyper-mitogenic drive coexists with mitotic incompetence in senescent cells. Cell Cycle 2012; 11:4642-9; PMID:23187803; http://dx.doi.org/10.4161/cc.22937
    • (2012) Cell Cycle , vol.11 , pp. 4642-4649
    • Leontieva, O.V.1    Lenzo, F.2    Demidenko, Z.N.3    Blagosklonny, M.V.4
  • 54
    • 58149175555 scopus 로고    scopus 로고
    • The life of a cell: Apoptosis regulation by the PI3K/PKB pathway
    • PMID:18842113
    • Duronio V. The life of a cell: apoptosis regulation by the PI3K/PKB pathway. Biochem J 2008; 415:333-44; PMID:18842113; http://dx.doi.org/10.1042/ BJ20081056
    • (2008) Biochem J , vol.415 , pp. 333-344
    • Duronio, V.1
  • 55
    • 17144395975 scopus 로고    scopus 로고
    • The activation of Akt/PKB signaling pathway and cell survival
    • PMID:15784165
    • Song G, Ouyang G, Bao S. The activation of Akt/PKB signaling pathway and cell survival. J Cell Mol Med 2005; 9:59-71; PMID:15784165; http://dx.doi.org/ 10.1111/j.1582-4934.2005.tb00337.x
    • (2005) J Cell Mol Med , vol.9 , pp. 59-71
    • Song, G.1    Ouyang, G.2    Bao, S.3
  • 58
    • 34247149015 scopus 로고    scopus 로고
    • The regulation of cyclin D1 degradation: Roles in cancer development and the potential for therapeutic invention
    • PMID:17407548
    • Alao JP. The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention. Mol Cancer 2007; 6:24; PMID:17407548; http://dx.doi.org/10.1186/1476-4598-6-24
    • (2007) Mol Cancer , vol.6 , pp. 24
    • Alao, J.P.1
  • 61
    • 38449099424 scopus 로고    scopus 로고
    • Prognostic significance of cyclin D1 and p16 in patients with intermediate-risk head and neck squamous cell carcinoma treated with docetaxel and concurrent radiotherapy
    • PMID:17563903
    • Higuchi E, Oridate N, Homma A, Suzuki F, Atago Y, Nagahashi T, Furuta Y, Fukuda S. Prognostic significance of cyclin D1 and p16 in patients with intermediate-risk head and neck squamous cell carcinoma treated with docetaxel and concurrent radiotherapy. Head Neck 2007; 29:940-7; PMID:17563903; http://dx.doi.org/10.1002/hed.20632
    • (2007) Head Neck , vol.29 , pp. 940-947
    • Higuchi, E.1    Oridate, N.2    Homma, A.3    Suzuki, F.4    Atago, Y.5    Nagahashi, T.6    Furuta, Y.7    Fukuda, S.8
  • 62
    • 3042743988 scopus 로고    scopus 로고
    • Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt
    • PMID:15231645
    • Yang L, Dan HC, Sun M, Liu Q, Sun XM, Feldman RI, Hamilton AD, Polokoff M, Nicosia SV, Herlyn M, et al. Akt/protein kinase B signaling inhibitor-2, a selective small molecule inhibitor of Akt signaling with antitumor activity in cancer cells overexpressing Akt. Cancer Res 2004; 64:4394-9; PMID:15231645; http://dx.doi.org/10.1158/0008-5472.CAN-04-0343
    • (2004) Cancer Res , vol.64 , pp. 4394-4399
    • Yang, L.1    Dan, H.C.2    Sun, M.3    Liu, Q.4    Sun, X.M.5    Feldman, R.I.6    Hamilton, A.D.7    Polokoff, M.8    Nicosia, S.V.9    Herlyn, M.10
  • 63
    • 0027333359 scopus 로고
    • A phase II trial of tricyclic nucleoside phosphate in patients with advanced squamous cell carcinoma of the cervix
    • A Gynecologic Oncology Group Study PMID:8256767
    • Feun LG, Blessing JA, Barrett RJ, Hanjani P. A phase II trial of tricyclic nucleoside phosphate in patients with advanced squamous cell carcinoma of the cervix. A Gynecologic Oncology Group Study. Am J Clin Oncol 1993; 16:506-8; PMID:8256767; http://dx.doi.org/10.1097/00000421-199312000-00010
    • (1993) Am J Clin Oncol , vol.16 , pp. 506-508
    • Feun, L.G.1    Blessing, J.A.2    Barrett, R.J.3    Hanjani, P.4
  • 65
    • 79955578793 scopus 로고    scopus 로고
    • Targeting the AKT/GSK3β/cyclin D1/Cdk4 survival signaling pathway for eradication of tumor radioresistance acquired by fractionated radiotherapy
    • PMID:21398050
    • Shimura T, Kakuda S, Ochiai Y, Kuwahara Y, Takai Y, Fukumoto M. Targeting the AKT/GSK3β/cyclin D1/Cdk4 survival signaling pathway for eradication of tumor radioresistance acquired by fractionated radiotherapy. Int J Radiat Oncol Biol Phys 2011; 80:540-8; PMID:21398050; http://dx.doi.org/10.1016/j.ijrobp. 2010.12.065
    • (2011) Int J Radiat Oncol Biol Phys , vol.80 , pp. 540-548
    • Shimura, T.1    Kakuda, S.2    Ochiai, Y.3    Kuwahara, Y.4    Takai, Y.5    Fukumoto, M.6


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