In vivo formation of γ-H2AX and 53BP1 DNA repair foci in blood cells after radioiodine therapy of differentiated thyroid cancer

Journal of Nuclear Medicine

Volumn 51, Issue 8, 2010, Pages 1318-1325

  Lassmann, Michael ^a   Hänscheid, Heribert ^a   Gassen, Daniela ^b   Biko, Johannes ^a   Meineke, Viktor ^b   Reiners, Christoph ^a   Scherthan, Harry ^b  

^a UNIVERSITY OF WÜRZBURG   (Germany)

^b UNIVERSITY OF ULM   (Germany)

Author keywords

H2AX; 53BP1; 131I; Biological dosimetry; Radionuclide therapy

Indexed keywords

BINDING PROTEIN; BIOLOGICAL MARKER; GAMMA HISTONE H2AX; HISTONE H2AX; IODINE 131; P53 BINDING PROTEIN 1; RECOMBINANT THYROTROPIN; UNCLASSIFIED DRUG; H2AFX PROTEIN, HUMAN; HISTONE; RADIOACTIVE IODINE; SIGNAL PEPTIDE; TP53BP1 PROTEIN, HUMAN;

ADULT; AGED; ARTICLE; BLOOD CELL; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; DNA REPAIR; DOSIMETRY; FEMALE; HUMAN; HYPOTHYROIDISM; LEUKOCYTE; MALE; PRIORITY JOURNAL; RADIATION ABSORPTION; RADIATION DOSE; RADIATION EXPOSURE; THYROID CANCER; WHOLE BODY RADIATION; ALGORITHM; BLOOD; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; METABOLISM; MIDDLE AGED; PATHOLOGY; RADIATION RESPONSE; THYROID TUMOR; THYROIDECTOMY;

ADULT; AGED; ALGORITHMS; BLOOD CELLS; DNA BREAKS, DOUBLE-STRANDED; DNA DAMAGE; DNA REPAIR; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HISTONES; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; IODINE RADIOISOTOPES; MALE; MIDDLE AGED; THYROID NEOPLASMS; THYROIDECTOMY; WHOLE-BODY IRRADIATION;

EID: 77956208698     PISSN: 01615505     EISSN: None     Source Type: Journal    
DOI: 10.2967/jnumed.109.071357     Document Type: Article

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