-
1
-
-
0141757494
-
Regulation and mechanisms of mammalian double-strand break repair
-
DOI 10.1038/sj.onc.1206679
-
K. Valerie, and L.F. Povirk Regulation and mechanisms of mammalian double-strand break repair Oncogene 22 2003 5792 5812 (Pubitemid 37176701)
-
(2003)
Oncogene
, vol.22
, Issue.REV. ISS. 3
, pp. 5792-5812
-
-
Valerie, K.1
Povirk, L.F.2
-
2
-
-
34249947699
-
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
-
DOI 10.1126/science.1140321
-
S. Matsuoka, B.A. Ballif, and A. Smogorzewska ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage Science 316 2007 1160 1166 (Pubitemid 46877472)
-
(2007)
Science
, vol.316
, Issue.5828
, pp. 1160-1166
-
-
Matsuoka, S.1
Ballif, B.A.2
Smogorzewska, A.3
McDonald III, E.R.4
Hurov, K.E.5
Luo, J.6
Bakalarski, C.E.7
Zhao, Z.8
Solimini, N.9
Lerenthal, Y.10
Shiloh, Y.11
Gygi, S.P.12
Elledge, S.J.13
-
3
-
-
0024195429
-
DNA damage produced by ionizing radiation in mammalian cells: Identities, mechanisms of formation, and reparability
-
J.F. Ward DNA damage produced by ionizing radiation in mammalian cells: identities, mechanisms of formation, and reparability Prog Nucleic Acid Res Mol Biol 35 1988 95 125
-
(1988)
Prog Nucleic Acid Res Mol Biol
, vol.35
, pp. 95-125
-
-
Ward, J.F.1
-
4
-
-
2442555209
-
Double Strand Break Repair by Homologous Recombination Is Regulated by Cell Cycle-independent Signaling via ATM in Human Glioma Cells
-
DOI 10.1074/jbc.M314191200
-
S.E. Golding, E. Rosenberg, and A. Khalil Double strand break repair by homologous recombination is regulated by cell cycle-independent signaling via ATM in human glioma cells J Biol Chem 279 2004 15402 15410 (Pubitemid 38618939)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.15
, pp. 15402-15410
-
-
Golding, S.E.1
Rosenberg, E.2
Khalil, A.3
McEwen, A.4
Holmes, M.5
Neill, S.6
Povirk, L.F.7
Valerie, K.8
-
5
-
-
9744220428
-
A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to γ-H2AX foci
-
DOI 10.1016/j.molcel.2004.10.029, PII S1097276504006549
-
E. Riballo, M. Kuhne, and N. Rief A pathway of double-strand break rejoining dependent upon ATM, Artemis, and proteins locating to gamma-H2AX foci Mol Cell 16 2004 715 724 (Pubitemid 39586530)
-
(2004)
Molecular Cell
, vol.16
, Issue.5
, pp. 715-724
-
-
Riballo, E.1
Kuhne, M.2
Rief, N.3
Doherty, A.4
Smith, G.C.M.5
Recio, M.-J.6
Reis, C.7
Dahm, K.8
Fricke, A.9
Krempler, A.10
Parker, A.R.11
Jackson, S.P.12
Gennery, A.13
Jeggo, P.A.14
Lobrich, M.15
-
6
-
-
47349107760
-
ATM Signaling Facilitates Repair of DNA Double-Strand Breaks Associated with Heterochromatin
-
DOI 10.1016/j.molcel.2008.05.017, PII S109727650800395X
-
A.A. Goodarzi, A.T. Noon, and D. Deckbar ATM signaling facilitates repair of DNA double-strand breaks associated with heterochromatin Mol Cell 31 2008 167 177 (Pubitemid 352001394)
-
(2008)
Molecular Cell
, vol.31
, Issue.2
, pp. 167-177
-
-
Goodarzi, A.A.1
Noon, A.T.2
Deckbar, D.3
Ziv, Y.4
Shiloh, Y.5
Lobrich, M.6
Jeggo, P.A.7
-
7
-
-
3242875642
-
The DNA-dependent protein kinase: The director at the end
-
DOI 10.1111/j.0105-2896.2004.00162.x
-
K. Meek, S. Gupta, D.A. Ramsden, and S.P. Lees-Miller The DNA-dependent protein kinase: the director at the end Immunol Rev 200 2004 132 141 (Pubitemid 38998198)
-
(2004)
Immunological Reviews
, vol.200
, pp. 132-141
-
-
Meek, K.1
Gupta, S.2
Ramsden, D.A.3
Lees-Miller, S.P.4
-
9
-
-
33747888634
-
Modeling oncogenic translocations: Distinct roles for double-strand break repair pathways in translocation formation in mammalian cells
-
DOI 10.1016/j.dnarep.2006.05.028, PII S1568786406001686, Mechanisms of Chromosomal Translocations
-
D.M. Weinstock, C.A. Richardson, B. Elliott, and M. Jasin Modeling oncogenic translocations: distinct roles for double-strand break repair pathways in translocation formation in mammalian cells DNA Repair (Amst) 5 2006 1065 1074 (Pubitemid 44291619)
-
(2006)
DNA Repair
, vol.5
, Issue.9-10
, pp. 1065-1074
-
-
Weinstock, D.M.1
Richardson, C.A.2
Elliott, B.3
Jasin, M.4
-
10
-
-
0035834693
-
ATM phosphorylates histone H2AX in response to DNA double-strand breaks
-
S. Burma, B.P. Chen, M. Murphy, A. Kurimasa, and D.J. Chen ATM phosphorylates histone H2AX in response to DNA double-strand breaks J Biol Chem 276 2001 42462 42467
-
(2001)
J Biol Chem
, vol.276
, pp. 42462-42467
-
-
Burma, S.1
Chen, B.P.2
Murphy, M.3
Kurimasa, A.4
Chen, D.J.5
-
11
-
-
1942538492
-
ATM and DNA-PK Function Redundantly to Phosphorylate H2AX after Exposure to Ionizing Radiation
-
DOI 10.1158/0008-5472.CAN-03-3207
-
T. Stiff, M. O'Driscoll, N. Rief, K. Iwabuchi, M. Lobrich, and P.A. Jeggo ATM and DNA-PK function redundantly to phosphorylate H2AX after exposure to ionizing radiation Cancer Res 64 2004 2390 2396 (Pubitemid 38523891)
-
(2004)
Cancer Research
, vol.64
, Issue.7
, pp. 2390-2396
-
-
Stiff, T.1
O'Driscoll, M.2
Rief, N.3
Iwabuchi, K.4
Lobrich, M.5
Jeggo, P.A.6
-
12
-
-
70350238489
-
Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion
-
S.E. Golding, E. Rosenberg, and N. Valerie Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion Mol Cancer Ther 8 2009 2894 2902
-
(2009)
Mol Cancer Ther
, vol.8
, pp. 2894-2902
-
-
Golding, S.E.1
Rosenberg, E.2
Valerie, N.3
-
13
-
-
0042632901
-
Pathways of DNA double-strand break repair during the mammalian cell cycle
-
DOI 10.1128/MCB.23.16.5706-5715.2003
-
K. Rothkamm, I. Kruger, L.H. Thompson, and M. Lobrich Pathways of DNA double-strand break repair during the mammalian cell cycle Mol Cell Biol 23 2003 5706 5715 (Pubitemid 36951334)
-
(2003)
Molecular and Cellular Biology
, vol.23
, Issue.16
, pp. 5706-5715
-
-
Rothkamm, K.1
Kruger, I.2
Thompson, L.H.3
Lobrich, M.4
-
14
-
-
77956327999
-
Dynamic dependence on ATR and ATM for double-strand break repair in human embryonic stem cells and neural descendants
-
B.R. Adams, S.E. Golding, R.R. Rao, and K. Valerie Dynamic dependence on ATR and ATM for double-strand break repair in human embryonic stem cells and neural descendants PLoS One 5 2010 e10001
-
(2010)
PLoS One
, vol.5
, pp. 10001
-
-
Adams, B.R.1
Golding, S.E.2
Rao, R.R.3
Valerie, K.4
-
16
-
-
66149094649
-
Prosurvival AKT and ERK signaling from EGFR and mutant EGFRvIII enhances DNA double-strand break repair in human glioma cells
-
S.E. Golding, R.N. Morgan, B.R. Adams, A.J. Hawkins, L.F. Povirk, and K. Valerie Prosurvival AKT and ERK signaling from EGFR and mutant EGFRvIII enhances DNA double-strand break repair in human glioma cells Cancer Biol Ther 8 2009 730 738
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 730-738
-
-
Golding, S.E.1
Morgan, R.N.2
Adams, B.R.3
Hawkins, A.J.4
Povirk, L.F.5
Valerie, K.6
-
17
-
-
33847066413
-
Extracellular signal-related kinase positively regulates ataxia telangiectasia mutated, homologous recombination repair, and the DNA damage response
-
S.E. Golding, E. Rosenberg, S. Neill, P. Dent, L.F. Povirk, and K. Valerie Extracellular signal-related kinase positively regulates ataxia telangiectasia mutated, homologous recombination repair, and the DNA damage response Cancer Res 67 2007 1046 1053
-
(2007)
Cancer Res
, vol.67
, pp. 1046-1053
-
-
Golding, S.E.1
Rosenberg, E.2
Neill, S.3
Dent, P.4
Povirk, L.F.5
Valerie, K.6
-
18
-
-
69949134989
-
Receptor signaling as a regulatory mechanism of DNA repair
-
R.E. Meyn, A. Munshi, J.V. Haymach, L. Milas, and K.K. Ang Receptor signaling as a regulatory mechanism of DNA repair Radiother Oncol: J Eur Soc Ther Radiol Oncol 92 2009 316 322
-
(2009)
Radiother Oncol: J Eur Soc Ther Radiol Oncol
, vol.92
, pp. 316-322
-
-
Meyn, R.E.1
Munshi, A.2
Haymach, J.V.3
Milas, L.4
Ang, K.K.5
-
19
-
-
0042838298
-
EGFRvIII-mediated radioresistance through a strong cytoprotective response
-
DOI 10.1038/sj.onc.1206788
-
G. Lammering, T.H. Hewit, and K. Valerie EGFRvIII-mediated radioresistance through a strong cytoprotective response Oncogene 22 2003 5545 5553 (Pubitemid 37102689)
-
(2003)
Oncogene
, vol.22
, Issue.36
, pp. 5545-5553
-
-
Lammering, G.1
Hewit, T.H.2
Valerie, K.3
Contessa, J.N.4
Amorino, G.P.5
Dent, P.6
Schmidt-Ullrich, R.K.7
-
20
-
-
78149358861
-
ErbB2 expression through heterodimerization with erbB1 is necessary for ionizing radiation- but not EGF-induced activation of Akt survival pathway
-
M. Toulany, M. Minjgee, R. Kehlbach, J. Chen, M. Baumann, and H.P. Rodemann ErbB2 expression through heterodimerization with erbB1 is necessary for ionizing radiation- but not EGF-induced activation of Akt survival pathway Radiother Oncol: J Eur Soc Ther Radiol Oncol 97 2010 338 345
-
(2010)
Radiother Oncol: J Eur Soc Ther Radiol Oncol
, vol.97
, pp. 338-345
-
-
Toulany, M.1
Minjgee, M.2
Kehlbach, R.3
Chen, J.4
Baumann, M.5
Rodemann, H.P.6
-
21
-
-
36849032852
-
Radiation-induced EGFR-signaling and control of DNA-damage repair
-
DOI 10.1080/09553000701769970, PII 787783391
-
H.P. Rodemann, K. Dittmann, and M. Toulany Radiation-induced EGFR-signaling and control of DNA-damage repair Int J Radiat Biol 83 2007 781 791 (Pubitemid 350219102)
-
(2007)
International Journal of Radiation Biology
, vol.83
, Issue.11-12
, pp. 781-791
-
-
Rodemann, H.P.1
Dittmann, K.2
Toulany, M.3
-
22
-
-
51049105757
-
Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA doublestrand break repair
-
M. Toulany, R. Kehlbach, and U. Florczak Targeting of AKT1 enhances radiation toxicity of human tumor cells by inhibiting DNA-PKcs-dependent DNA doublestrand break repair Mol Cancer Ther 7 2008 1772 1781
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 1772-1781
-
-
Toulany, M.1
Kehlbach, R.2
Florczak, U.3
-
23
-
-
66249149058
-
EGFRvIII and DNA double-strand break repair: A molecular mechanism for radioresistance in glioblastoma
-
B. Mukherjee, B. McEllin, and C.V. Camacho EGFRvIII and DNA double-strand break repair: a molecular mechanism for radioresistance in glioblastoma Cancer Res 69 2009 4252 4259
-
(2009)
Cancer Res
, vol.69
, pp. 4252-4259
-
-
Mukherjee, B.1
McEllin, B.2
Camacho, C.V.3
-
24
-
-
77955655466
-
Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation
-
F. Wei, Y. Xie, L. Tao, and D. Tang Both ERK1 and ERK2 kinases promote G2/M arrest in etoposide-treated MCF7 cells by facilitating ATM activation Cell Signal 22 2010 1783 1789
-
(2010)
Cell Signal
, vol.22
, pp. 1783-1789
-
-
Wei, F.1
Xie, Y.2
Tao, L.3
Tang, D.4
-
25
-
-
77749233738
-
ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS
-
A. Alexander, S.L. Cai, and J. Kim ATM signals to TSC2 in the cytoplasm to regulate mTORC1 in response to ROS Proc Natl Acad Sci USA 107 2010 4153 4158
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 4153-4158
-
-
Alexander, A.1
Cai, S.L.2
Kim, J.3
-
26
-
-
77958191599
-
ATM activation by oxidative stress
-
Z. Guo, S. Kozlov, M.F. Lavin, M.D. Person, and T.T. Paull ATM activation by oxidative stress Science 330 2010 517 521
-
(2010)
Science
, vol.330
, pp. 517-521
-
-
Guo, Z.1
Kozlov, S.2
Lavin, M.F.3
Person, M.D.4
Paull, T.T.5
-
27
-
-
0037335568
-
Stress and radiation-induced activation of multiple intracellular signaling pathways
-
DOI 10.1667/0033-7587(2003)159[0283:SARIAO]2.0.CO;2
-
P. Dent, A. Yacoub, and J. Contessa Stress and radiation-induced activation of multiple intracellular signaling pathways Radiat Res 159 2003 283 300 (Pubitemid 36314943)
-
(2003)
Radiation Research
, vol.159
, Issue.3
, pp. 283-300
-
-
Dent, P.1
Yacoub, A.2
Contessa, J.3
Caron, R.4
Amorino, G.5
Valerie, K.6
Hagan, M.P.7
Grant, S.8
Schmidt-Ullrich, R.9
-
28
-
-
34147190965
-
Radiation-induced cell signaling: Inside-out and outside-in
-
DOI 10.1158/1535-7163.MCT-06-0596
-
K. Valerie, A. Yacoub, and M.P. Hagan Radiation-induced cell signaling: inside-out and outside-in Mol Cancer Ther 6 2007 789 801 (Pubitemid 46554549)
-
(2007)
Molecular Cancer Therapeutics
, vol.6
, Issue.3
, pp. 789-801
-
-
Valerie, K.1
Yacoub, A.2
Hagan, M.P.3
Curiel, D.T.4
Fisher, P.B.5
Grant, S.6
Dent, P.7
-
29
-
-
0035937841
-
Epidermal growth factor sensitizes cells to ionizing radiation by down-regulating protein mutated in ataxia-telangiectasia
-
N. Gueven, K.E. Keating, and P. Chen Epidermal growth factor sensitizes cells to ionizing radiation by down-regulating protein mutated in ataxia-telangiectasia J Biol Chem 276 2001 8884 8891
-
(2001)
J Biol Chem
, vol.276
, pp. 8884-8891
-
-
Gueven, N.1
Keating, K.E.2
Chen, P.3
-
30
-
-
0035852706
-
ATM-dependent expression of the insulin-like growth factor-I receptor in a pathway regulating radiation response
-
DOI 10.1073/pnas.041416598
-
S. Peretz, R. Jensen, R. Baserga, and P.M. Glazer ATM-dependent expression of the insulin-like growth factor-I receptor in a pathway regulating radiation response Proc Natl Acad Sci USA 98 2001 1676 1681 (Pubitemid 32165557)
-
(2001)
Proceedings of the National Academy of Sciences of the United States of America
, vol.98
, Issue.4
, pp. 1676-1681
-
-
Peretz, S.1
Jensen, R.2
Baserga, R.3
Glazer, P.M.4
-
31
-
-
0035811559
-
Downregulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase
-
DOI 10.1038/sj.onc.1204565
-
V.M. Macaulay, A.J. Salisbury, E.A. Bohula, M.P. Playford, N.I. Smorodinsky, and Y. Shiloh Downregulation of the type 1 insulin-like growth factor receptor in mouse melanoma cells is associated with enhanced radiosensitivity and impaired activation of Atm kinase Oncogene 20 2001 4029 4040 (Pubitemid 32681608)
-
(2001)
Oncogene
, vol.20
, Issue.30
, pp. 4029-4040
-
-
Macaulay, V.M.1
Salisbury, A.J.2
Bohula, E.A.3
Playford, M.P.4
Smorodinsky, N.I.5
Shiloh, Y.6
-
32
-
-
79851506488
-
ATM-dependent ERK signaling via AKT in response to DNA double-strand breaks
-
A. Khalil, R.N. Morgan, and B.R. Adams ATM-dependent ERK signaling via AKT in response to DNA double-strand breaks Cell Cycle 10 2011 481 491
-
(2011)
Cell Cycle
, vol.10
, pp. 481-491
-
-
Khalil, A.1
Morgan, R.N.2
Adams, B.R.3
-
33
-
-
21444434296
-
UV-C light induces raft-associated acid sphingomyelinase and JNK activation and translocation independently on a nuclear signal
-
DOI 10.1074/jbc.M412867200
-
A. Charruyer, S. Grazide, C. Bezombes, S. Muller, G. Laurent, and J.P. Jaffrezou UV-C light induces raft-associated acid sphingomyelinase and JNK activation and translocation independently on a nuclear signal J Biol Chem 280 2005 19196 19204 (Pubitemid 41379626)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.19
, pp. 19196-19204
-
-
Charruyer, A.1
Grazide, S.2
Bezombes, C.3
Muller, S.4
Laurent, G.5
Jaffrezou, J.-P.6
-
34
-
-
0034806972
-
Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stress
-
DOI 10.1128/MCB.21.20.6913-6926.2001
-
M. Benhar, I. Dalyot, D. Engelberg, and A. Levitzki Enhanced ROS production in oncogenically transformed cells potentiates c-Jun N-terminal kinase and p38 mitogen-activated protein kinase activation and sensitization to genotoxic stress Mol Cell Biol 21 2001 6913 6926 (Pubitemid 32911252)
-
(2001)
Molecular and Cellular Biology
, vol.21
, Issue.20
, pp. 6913-6926
-
-
Benhar, M.1
Dalyot, I.2
Engelberg, D.3
Levitzki, A.4
-
35
-
-
0036184190
-
Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo
-
DOI 10.1016/S1097-2765(02)00445-8
-
T.C. Meng, T. Fukada, and N.K. Tonks Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo Mol Cell 9 2002 387 399 (Pubitemid 34195563)
-
(2002)
Molecular Cell
, vol.9
, Issue.2
, pp. 387-399
-
-
Meng, T.-C.1
Fukada, T.2
Tonks, N.K.3
-
36
-
-
33748743056
-
Oxidative inhibition of receptor-type protein-tyrosine phosphatase κ by ultraviolet irradiation activates epidermal growth factor receptor in human keratinocytes
-
DOI 10.1074/jbc.M602355200
-
Y. Xu, Y. Shao, J.J. Voorhees, and G.J. Fisher Oxidative inhibition of receptor-type proteintyrosine phosphatase kappa by ultraviolet irradiation activates epidermal growth factor receptor in human keratinocytes J Biol Chem 281 2006 27389 27397 (Pubitemid 44401766)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.37
, pp. 27389-27397
-
-
Xu, Y.1
Shao, Y.2
Voorhees, J.J.3
Fisher, G.J.4
-
37
-
-
78149464883
-
Serine/threonine phosphatases in the DNA damage response and cancer
-
A. Peng, and J.L. Maller Serine/threonine phosphatases in the DNA damage response and cancer Oncogene 29 2010 5977 5988
-
(2010)
Oncogene
, vol.29
, pp. 5977-5988
-
-
Peng, A.1
Maller, J.L.2
-
38
-
-
0141509963
-
Constitutive induction of p-Erk1/2 accompanied by reduced activities of protein phosphatases 1 and 2A and MKP3 due to reactive oxygen species during cellular senescence
-
DOI 10.1074/jbc.M211739200
-
H.S. Kim, M.C. Song, I.H. Kwak, T.J. Park, and I.K. Lim Constitutive induction of p-Erk1/2 accompanied by reduced activities of protein phosphatases 1 and 2A and MKP3 due to reactive oxygen species during cellular senescence J Biol Chem 278 2003 37497 37510 (Pubitemid 37175271)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.39
, pp. 37497-37510
-
-
Kim, H.S.1
Song, M.-C.2
Kwak, I.H.3
Park, T.J.4
Lim, I.K.5
-
39
-
-
0016430783
-
Cell cycle redistribution as a factor in multifraction irradiation
-
H.R. Withers Cell cycle redistribution as a factor in multifraction irradiation Radiology 114 1975 199 202
-
(1975)
Radiology
, vol.114
, pp. 199-202
-
-
Withers, H.R.1
-
40
-
-
0030772168
-
Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation
-
R.K. Schmidt-Ullrich, R.B. Mikkelsen, and P. Dent Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation Oncogene 15 1997 1191 1197 (Pubitemid 27429622)
-
(1997)
Oncogene
, vol.15
, Issue.10
, pp. 1191-1197
-
-
Schmidt-Ullrich, R.K.1
Mikkelsen, R.B.2
Dent, P.3
Todd, D.G.4
Valerie, K.5
Kavanagh, B.D.6
Contessa, J.N.7
Rorrer, W.K.8
Chen, P.B.9
-
41
-
-
0033398661
-
Molecular mechanisms of radiation-induced accelerated repopulation
-
R.K. Schmidt-Ullrich, J.N. Contessa, and P. Dent Molecular mechanisms of radiation-induced accelerated repopulation Radiat Oncol Invest 7 1999 321 330 (Pubitemid 30033351)
-
(1999)
Radiation Oncology Investigations
, vol.7
, Issue.6
, pp. 321-330
-
-
Schmidt-Ullrich, R.K.1
Contessa, J.N.2
Dent, P.3
Mikkelsen, R.B.4
Valerie, K.5
Reardon, D.B.6
Bowers, G.7
Lin, P.-S.8
|