In silico investigation of PHD-3 specific HIF1-α proline 567 hydroxylation: A new player in the VHL/HIF-1α interaction pathway?

FEBS Letters

Volumn 587, Issue 18, 2013, Pages 2996-3001

  Minervini, Giovanni ^a   Masiero, Alessandro ^a   Moro, Stefano ^a   Tosatto, Silvio C E ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Cancer; Hippel Lindau; Hypoxia inducible factor 1; Molecular dynamic von; Sequence analysis; Structural bioinformatic

Indexed keywords

HYPOXIA INDUCIBLE FACTOR; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; HYPOXIA INDUCIBLE FACTOR 3ALPHA; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROLINE; PROLYL HYDROXYLASE 3; UNCLASSIFIED DRUG; VON HIPPEL LINDAU PROTEIN;

ARTICLE; BETA SHEET; BINDING AFFINITY; COMPLEX FORMATION; COMPUTER MODEL; CONTROLLED STUDY; HYDROGEN BOND; HYDROXYLATION; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; SEQUENCE ANALYSIS; STRUCTURE ACTIVITY RELATION;

CANCER; HYPOXIA INDUCIBLE FACTOR 1; MOLECULAR DYNAMIC; SEQUENCE ANALYSIS; STRUCTURAL BIOINFORMATIC; VON HIPPEL-LINDAU;

AMINO ACID SEQUENCE; BINDING SITES; CONSERVED SEQUENCE; DIOXYGENASES; HUMANS; HYDROGEN BONDING; HYDROXYLATION; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN PROCESSING, POST-TRANSLATIONAL; SEQUENCE HOMOLOGY, AMINO ACID; SIGNAL TRANSDUCTION; STATIC ELECTRICITY; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

EID: 84883490214     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2013.07.019     Document Type: Article

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