Effects of point mutations in pVHL on the binding of HIF-1α

Proteins: Structure, Function and Bioinformatics

Volumn 80, Issue 3, 2012, Pages 733-746

  Domene, Carmen ^a   Illingworth, Christopher J R ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Conformation; Hypoxia; Molecular dynamics; Protein protein interaction

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; TYROSINE; VON HIPPEL LINDAU PROTEIN;

AMINO ACID SUBSTITUTION; ARTICLE; ATOM; COMPUTER ANALYSIS; GENE MUTATION; HEMANGIOBLASTOMA; HYDROGEN BOND; MOLECULAR DYNAMICS; PHENOTYPE; PHEOCHROMOCYTOMA; POINT MUTATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN STRUCTURE; WILD TYPE;

HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MOLECULAR DYNAMICS SIMULATION; POINT MUTATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STABILITY; VON HIPPEL-LINDAU DISEASE; VON HIPPEL-LINDAU TUMOR SUPPRESSOR PROTEIN;

ANIMALIA;

EID: 84856776976     PISSN: 08873585     EISSN: 10970134     Source Type: Journal    
DOI: 10.1002/prot.23230     Document Type: Article

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