Astrocytic and neuronal accumulation of elevated extracellular K+ with a 2/3 K+/Na+ flux ratio-consequences for energy metabolism, osmolarity and higher brain function

Frontiers in Computational Neuroscience

Volumn , Issue JUL, 2013, Pages

  Hertz, Leif ^a   Xu, Junnan ^a   Song, Dan ^a   Yan, Enzhi ^a   Gu, Li ^a   Peng, Liang ^a  

^a CHINA MEDICAL UNIVERSITY   (China)

Author keywords

Action potential; Astrocyte; Brain potassium homeostasis; Channel; Computational analysis; Kir; K+ ATPase; Na+; Neuron; Slow neuronal hyperpolarization

Indexed keywords

ACTION POTENTIALS; ASTROCYTE; CHANNEL; COMPUTATIONAL ANALYSIS; HYPERPOLARIZATION; POTASSIUM HOMEOSTASIS;

BRAIN; COMPUTATIONAL METHODS; ENZYME ACTIVITY; NEURONS; SODIUM;

ION EXCHANGE;

ADENOSINE TRIPHOSPHATASE; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); COTRANSPORTER; FUROSEMIDE; GAP JUNCTION PROTEIN; GLUTAMIC ACID; GLUTAMINE; HYPERTONIC SOLUTION; INWARDLY RECTIFYING POTASSIUM CHANNEL; INWARDLY RECTIFYING POTASSIUM CHANNEL SUBUNIT KIR4.1; POTASSIUM ION; PROTEIN NKCC1; SODIUM ION; UNCLASSIFIED DRUG;

ACTION POTENTIAL; AEROBIC METABOLISM; ASTROCYTE; BRAIN CELL; BRAIN FUNCTION; BRAIN NERVE CELL; DEPOLARIZATION; ENERGY METABOLISM; GLYCOGENOLYSIS; HUMAN; HYPERPOLARIZATION; NERVE CELL STIMULATION; NONHUMAN; OSMOLARITY; POTASSIUM TRANSPORT; REVIEW; SODIUM TRANSPORT; SYNAPSE;

EID: 84883403760     PISSN: 16625188     EISSN: None     Source Type: Journal    
DOI: 10.3389/fncom.2013.00114     Document Type: Review

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