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Volumn 115, Issue 4, 2010, Pages 1007-1023

Signaling pathways of isoproterenol-induced ERK1/2 phosphorylation in primary cultures of astrocytes are concentration-dependent

Author keywords

arrestin; 1 adrenoceptor; 2 adrenoceptor; EGF receptor; Src

Indexed keywords

4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; ADENYLATE CYCLASE; BETA 1 ADRENERGIC RECEPTOR; BETA 2 ADRENERGIC RECEPTOR; BETA ARRESTIN 1; BETA ARRESTIN 2; BETAXOLOL; CALCIUM ION; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; EPIDERMAL GROWTH FACTOR RECEPTOR; GLIAL FIBRILLARY ACIDIC PROTEIN; ILOMASTAT; ISOPRENALINE; METALLOPROTEINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PROTEIN TYROSINE KINASE;

EID: 77958615325     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2010.06995.x     Document Type: Article
Times cited : (32)

References (95)
  • 1
    • 0037452623 scopus 로고    scopus 로고
    • Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference
    • Ahn S., Nelson C. D., Garrison T. R., Miller W. E. and Lefkowitz R. J. (2003) Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference. Proc. Natl Acad. Sci. USA 100, 1740-1744.
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , pp. 1740-1744
    • Ahn, S.1    Nelson, C.D.2    Garrison, T.R.3    Miller, W.E.4    Lefkowitz, R.J.5
  • 2
    • 0038724937 scopus 로고    scopus 로고
    • Role of Raf in vascular protection from distinct apoptotic stimuli
    • Alavi A., Hood J. D., Frausto R., Stupack D. G. and Cheresh D. A. (2003) Role of Raf in vascular protection from distinct apoptotic stimuli. Science 301, 94-96.
    • (2003) Science , vol.301 , pp. 94-96
    • Alavi, A.1    Hood, J.D.2    Frausto, R.3    Stupack, D.G.4    Cheresh, D.A.5
  • 3
    • 0031279472 scopus 로고    scopus 로고
    • Differential timing for the appearance of neuronal and astrocytic beta-adrenergic receptors in the developing rat visual cortex as revealed by light and electron-microscopic immunocytochemistry
    • Aoki C. (1997) Differential timing for the appearance of neuronal and astrocytic beta-adrenergic receptors in the developing rat visual cortex as revealed by light and electron-microscopic immunocytochemistry. Vis. Neurosci. 14, 1129-1142.
    • (1997) Vis. Neurosci. , vol.14 , pp. 1129-1142
    • Aoki, C.1
  • 4
    • 52049121361 scopus 로고    scopus 로고
    • Locus coeruleus alpha-adrenergic-mediated activation of cortical astrocytes in vivo
    • Bekar L. K., He W. and Nedergaard M. (2008) Locus coeruleus alpha-adrenergic-mediated activation of cortical astrocytes in vivo. Cereb. Cortex 18, 2789-2795.
    • (2008) Cereb. Cortex , vol.18 , pp. 2789-2795
    • Bekar, L.K.1    He, W.2    Nedergaard, M.3
  • 5
    • 0018649048 scopus 로고
    • Sensitive gas chromatographic method for the determination in blood and urine of SL 75212 [4-(2-cyclopropylmethoxyethyl)-1-phenoxy-3-isopropylaminopropan-2-ol], a new beta 1 adrenoceptor blocking agent
    • Bianchetti G., Ganansia J. and Morselli P. L. (1979) Sensitive gas chromatographic method for the determination in blood and urine of SL 75212 [4-(2-cyclopropylmethoxyethyl)-1-phenoxy-3-isopropylaminopropan-2-ol], a new beta 1 adrenoceptor blocking agent. J. Chromatogr. 176, 134-139.
    • (1979) J. Chromatogr. , vol.176 , pp. 134-139
    • Bianchetti, G.1    Ganansia, J.2    Morselli, P.L.3
  • 6
    • 0033583220 scopus 로고    scopus 로고
    • c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function
    • Biscardi J. S., Maa M. C., Tice D. A., Cox M. E., Leu T. H. and Parsons S. J. (1999) c-Src-mediated phosphorylation of the epidermal growth factor receptor on Tyr845 and Tyr1101 is associated with modulation of receptor function. J. Biol. Chem. 274, 8335-8343.
    • (1999) J. Biol. Chem. , vol.274 , pp. 8335-8343
    • Biscardi, J.S.1    Maa, M.C.2    Tice, D.A.3    Cox, M.E.4    Leu, T.H.5    Parsons, S.J.6
  • 7
    • 0032912817 scopus 로고    scopus 로고
    • Phosphorylation of tyrosine 992, 1068, and 1086 is required for conformational change of the human epidermal growth factor receptor c-terminal tail
    • Bishayee A., Beguinot L. and Bishayee S. (1999) Phosphorylation of tyrosine 992, 1068, and 1086 is required for conformational change of the human epidermal growth factor receptor c-terminal tail. Mol. Biol. Cell 10, 525-536.
    • (1999) Mol. Biol. Cell , vol.10 , pp. 525-536
    • Bishayee, A.1    Beguinot, L.2    Bishayee, S.3
  • 8
    • 3543025709 scopus 로고    scopus 로고
    • Phosphorylation of Y845 on the epidermal growth factor receptor mediates binding to the mitochondrial protein cytochrome c oxidase subunit II
    • Boerner J. L., Demory M. L., Silva C. and Parsons S. J. (2004) Phosphorylation of Y845 on the epidermal growth factor receptor mediates binding to the mitochondrial protein cytochrome c oxidase subunit II. Mol. Cell Biol. 24, 7059-7071.
    • (2004) Mol. Cell Biol. , vol.24 , pp. 7059-7071
    • Boerner, J.L.1    Demory, M.L.2    Silva, C.3    Parsons, S.J.4
  • 9
    • 28844486282 scopus 로고    scopus 로고
    • Transactivating agonists of the EGF receptor require Tyr 845 phosphorylation for induction of DNA synthesis
    • Boerner J. L., Biscardi J. S., Silva C. M. and Parsons S. J. (2005) Transactivating agonists of the EGF receptor require Tyr 845 phosphorylation for induction of DNA synthesis. Mol. Carcinog. 44, 262-273.
    • (2005) Mol. Carcinog. , vol.44 , pp. 262-273
    • Boerner, J.L.1    Biscardi, J.S.2    Silva, C.M.3    Parsons, S.J.4
  • 10
    • 0033860695 scopus 로고    scopus 로고
    • The EGF receptor: a nexus for trafficking and signaling
    • Carpenter G. (2000) The EGF receptor: a nexus for trafficking and signaling. Bioessays 22, 697-707.
    • (2000) Bioessays , vol.22 , pp. 697-707
    • Carpenter, G.1
  • 11
    • 0030613761 scopus 로고    scopus 로고
    • Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A
    • Daaka Y., Luttrell L. M. and Lefkowitz R. J. (1997) Switching of the coupling of the beta2-adrenergic receptor to different G proteins by protein kinase A. Nature 390, 88-91.
    • (1997) Nature , vol.390 , pp. 88-91
    • Daaka, Y.1    Luttrell, L.M.2    Lefkowitz, R.J.3
  • 14
    • 43049156290 scopus 로고    scopus 로고
    • c-Src trafficking and co-localization with the EGF receptor promotes EGF ligand-independent EGF receptor activation and signaling
    • Donepudi M. and Resh M. D. (2008) c-Src trafficking and co-localization with the EGF receptor promotes EGF ligand-independent EGF receptor activation and signaling. Cell. Signal. 20, 1359-1367.
    • (2008) Cell. Signal. , vol.20 , pp. 1359-1367
    • Donepudi, M.1    Resh, M.D.2
  • 15
    • 33747033500 scopus 로고    scopus 로고
    • Ligand-independent and EGF receptor-supported transactivation: lessons from beta2-adrenergic receptor signalling
    • Drube S., Stirnweiss J., Valkova C. and Liebmann C. (2006) Ligand-independent and EGF receptor-supported transactivation: lessons from beta2-adrenergic receptor signalling. Cell. Signal. 18, 1633-1646.
    • (2006) Cell. Signal. , vol.18 , pp. 1633-1646
    • Drube, S.1    Stirnweiss, J.2    Valkova, C.3    Liebmann, C.4
  • 16
    • 69349103856 scopus 로고    scopus 로고
    • ERK phosphorylation in intact, adult brain by alpha(2)-adrenergic transactivation of EGF receptors
    • Du T., Li B., Liu S., Zang P., Prevot V., Hertz L. and Peng L. (2009) ERK phosphorylation in intact, adult brain by alpha(2)-adrenergic transactivation of EGF receptors. Neurochem. Int. 55, 593-600.
    • (2009) Neurochem. Int. , vol.55 , pp. 593-600
    • Du, T.1    Li, B.2    Liu, S.3    Zang, P.4    Prevot, V.5    Hertz, L.6    Peng, L.7
  • 17
    • 0019508670 scopus 로고
    • Characteristics of the beta 1-and beta 2-adrenergic-sensitive adenylate cyclases in glial cell primary cultures and their comparison with beta 2-adrenergic-sensitive adenylate cyclase of meningeal cells
    • Ebersolt C., Perez M., Vassent G. and Bockaert J. (1981) Characteristics of the beta 1-and beta 2-adrenergic-sensitive adenylate cyclases in glial cell primary cultures and their comparison with beta 2-adrenergic-sensitive adenylate cyclase of meningeal cells. Brain Res. 213, 151-61.
    • (1981) Brain Res. , vol.213 , pp. 151-61
    • Ebersolt, C.1    Perez, M.2    Vassent, G.3    Bockaert, J.4
  • 18
    • 0023154077 scopus 로고
    • Dissociation of the stellate morphology from intracellular cyclic AMP levels in cultured rat brain astroglial cells: effects of ganglioside GM1 and lysophosphatidylserine
    • Facci L., Skaper S. D., Levin D. L. and Varon S. (1987) Dissociation of the stellate morphology from intracellular cyclic AMP levels in cultured rat brain astroglial cells: effects of ganglioside GM1 and lysophosphatidylserine. J. Neurochem. 48, 566-573.
    • (1987) J. Neurochem. , vol.48 , pp. 566-573
    • Facci, L.1    Skaper, S.D.2    Levin, D.L.3    Varon, S.4
  • 20
    • 0033017879 scopus 로고    scopus 로고
    • Stimulation of the extracellular signal-regulated kinase 1/2 pathway by human beta-3 adrenergic receptor: new pharmacological profile and mechanism of activation
    • Gerhardt C. C., Gros J., Strosberg A. D. and Issad T. (1999) Stimulation of the extracellular signal-regulated kinase 1/2 pathway by human beta-3 adrenergic receptor: new pharmacological profile and mechanism of activation. Mol. Pharmacol. 55, 255-262.
    • (1999) Mol. Pharmacol. , vol.55 , pp. 255-262
    • Gerhardt, C.C.1    Gros, J.2    Strosberg, A.D.3    Issad, T.4
  • 21
    • 0347363614 scopus 로고    scopus 로고
    • Delayed but sustained induction of mitogen-activated protein kinase activity is associated with beta-adrenergic receptor-mediated morphological differentiation of astrocytes
    • Gharami K. and Das S. (2004) Delayed but sustained induction of mitogen-activated protein kinase activity is associated with beta-adrenergic receptor-mediated morphological differentiation of astrocytes. J. Neurochem. 88, 12-22.
    • (2004) J. Neurochem. , vol.88 , pp. 12-22
    • Gharami, K.1    Das, S.2
  • 22
    • 44449114745 scopus 로고    scopus 로고
    • Astrocytic involvement in learning and memory consolidation
    • Gibbs M. E., Hutchinson D. and Hertz L. (2008) Astrocytic involvement in learning and memory consolidation. Neurosci. Biobehav. Rev. 32, 927-944.
    • (2008) Neurosci. Biobehav. Rev. , vol.32 , pp. 927-944
    • Gibbs, M.E.1    Hutchinson, D.2    Hertz, L.3
  • 23
    • 0027495705 scopus 로고
    • Dependence of hepatocytic autophagy on intracellularly sequestered calcium
    • Gordon P. B., Holen I., Fosse M., Røtnes J. S. and Seglen P. O. (1993) Dependence of hepatocytic autophagy on intracellularly sequestered calcium. J. Biol. Chem. 268, 26107-26112.
    • (1993) J. Biol. Chem. , vol.268 , pp. 26107-26112
    • Gordon, P.B.1    Holen, I.2    Fosse, M.3    Røtnes, J.S.4    Seglen, P.O.5
  • 24
    • 0036783747 scopus 로고    scopus 로고
    • Duality of G protein-coupled mechanisms for beta-adrenergic activation of NKCC activity in skeletal muscle
    • Gosmanov A. R., Wong J. A. and Thomason D. B. (2002) Duality of G protein-coupled mechanisms for beta-adrenergic activation of NKCC activity in skeletal muscle. Am. J. Physiol. Cell Physiol. 283, C1025-1032.
    • (2002) Am. J. Physiol. Cell Physiol. , vol.283
    • Gosmanov, A.R.1    Wong, J.A.2    Thomason, D.B.3
  • 25
    • 4744342856 scopus 로고    scopus 로고
    • Direct interaction of Cbl with pTyr 1045 of the EGF receptor (EGFR) is required to sort the EGFR to lysosomes for degradation
    • Grøvdal L. M., Stang E., Sorkin A. and Madshus I. H. (2004) Direct interaction of Cbl with pTyr 1045 of the EGF receptor (EGFR) is required to sort the EGFR to lysosomes for degradation. Exp. Cell Res. 300, 388-395.
    • (2004) Exp. Cell Res. , vol.300 , pp. 388-395
    • Grøvdal, L.M.1    Stang, E.2    Sorkin, A.3    Madshus, I.H.4
  • 26
    • 34250202181 scopus 로고    scopus 로고
    • Depolarization-induced, glutamate receptor-mediated, and transactivation-dependent extracellular-signal regulated kinase phosphorylation in cultured cerebellar granule neurons
    • Gu L., Li B., Yang X., Hu X., Huang X., Hertz L. and Peng L. (2007) Depolarization-induced, glutamate receptor-mediated, and transactivation-dependent extracellular-signal regulated kinase phosphorylation in cultured cerebellar granule neurons. Neuroscience 147, 342-353.
    • (2007) Neuroscience , vol.147 , pp. 342-353
    • Gu, L.1    Li, B.2    Yang, X.3    Hu, X.4    Huang, X.5    Hertz, L.6    Peng, L.7
  • 28
    • 33751109238 scopus 로고    scopus 로고
    • Hypophosphorylation of residue Y1045 leads to defective downregulation of EGFRvIII
    • Han W., Zhang T., Yu H., Foulke J. G. and Tang C. K. (2006) Hypophosphorylation of residue Y1045 leads to defective downregulation of EGFRvIII. Cancer Biol. Ther. 5, 1361-1368.
    • (2006) Cancer Biol. Ther. , vol.5 , pp. 1361-1368
    • Han, W.1    Zhang, T.2    Yu, H.3    Foulke, J.G.4    Tang, C.K.5
  • 30
    • 0017839638 scopus 로고
    • Kinetic characteristics of the glutamate uptake into normal astrocytes in cultures
    • Hertz L., Schousboe A., Boechler N., Mukerji S. and Fedoroff S. (1978) Kinetic characteristics of the glutamate uptake into normal astrocytes in cultures. Neurochem. Res. 3, 1-14.
    • (1978) Neurochem. Res. , vol.3 , pp. 1-14
    • Hertz, L.1    Schousboe, A.2    Boechler, N.3    Mukerji, S.4    Fedoroff, S.5
  • 31
    • 0024577524 scopus 로고
    • Potassium induced calcium uptake in astrocytes and its potent inhibition by a calcium channel blocker
    • Hertz L., Bender A. S., Woodbury D. and White S. A. (1989) Potassium induced calcium uptake in astrocytes and its potent inhibition by a calcium channel blocker. J. Neurosci. Res. 22, 209-215.
    • (1989) J. Neurosci. Res. , vol.22 , pp. 209-215
    • Hertz, L.1    Bender, A.S.2    Woodbury, D.3    White, S.A.4
  • 32
    • 0032468697 scopus 로고    scopus 로고
    • Functional studies in cultured astrocytes
    • Hertz L., Peng L. and Lai J. C. (1998) Functional studies in cultured astrocytes. Methods 16, 293-310.
    • (1998) Methods , vol.16 , pp. 293-310
    • Hertz, L.1    Peng, L.2    Lai, J.C.3
  • 33
    • 3042758057 scopus 로고    scopus 로고
    • Astrocytic adrenoceptors: a major drug target in neurological and psychiatric disorder?
    • Hertz L., Chen Y., Gibbs M. E. and Zang Peng P. L. (2004) Astrocytic adrenoceptors: a major drug target in neurological and psychiatric disorder? Curr. Drug Targets CNS Neurol. Disord. 3, 239-268.
    • (2004) Curr. Drug Targets CNS Neurol. Disord. , vol.3 , pp. 239-268
    • Hertz, L.1    Chen, Y.2    Gibbs, M.E.3    Zang Peng, P.L.4
  • 34
    • 33846423878 scopus 로고    scopus 로고
    • Energy metabolism in astrocytes: high rate of oxidative metabolism and spatiotemporal dependence on glycolysis/glycogenolysis
    • Hertz L., Peng L. and Dienel G. A. (2007) Energy metabolism in astrocytes: high rate of oxidative metabolism and spatiotemporal dependence on glycolysis/glycogenolysis. J. Cereb. Blood Flow Metab. 27, 219-249.
    • (2007) J. Cereb. Blood Flow Metab. , vol.27 , pp. 219-249
    • Hertz, L.1    Peng, L.2    Dienel, G.A.3
  • 35
    • 77956226559 scopus 로고    scopus 로고
    • Adrenoceptors in brain: cellular gene expression and effects on astrocytic metabolism and [Ca2+]i
    • Hertz L., Lovatt D., Goldman S. A. and Nedergaard M. (2010) Adrenoceptors in brain: cellular gene expression and effects on astrocytic metabolism and [Ca2+]i. Neurochem. Int. E-Pub April 7, 2010.
    • (2010) Neurochem. Int. E-Pub April , vol.7
    • Hertz, L.1    Lovatt, D.2    Goldman, S.A.3    Nedergaard, M.4
  • 36
    • 36249019009 scopus 로고    scopus 로고
    • Epac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors
    • Holz G. G., Chepurny O. G. and Schwede F. (2008) Epac-selective cAMP analogs: new tools with which to evaluate the signal transduction properties of cAMP-regulated guanine nucleotide exchange factors. Cell. Signal. 20, 10-20.
    • (2008) Cell. Signal. , vol.20 , pp. 10-20
    • Holz, G.G.1    Chepurny, O.G.2    Schwede, F.3
  • 37
    • 0037059786 scopus 로고    scopus 로고
    • G protein-coupled receptor kinase 5 regulates beta 1-adrenergic receptor association with PSD-95
    • Hu L. A., Chen W., Premont R. T., Cong M. and Lefkowitz R. J. (2002) G protein-coupled receptor kinase 5 regulates beta 1-adrenergic receptor association with PSD-95. J. Biol. Chem. 277, 1607-1613.
    • (2002) J. Biol. Chem. , vol.277 , pp. 1607-1613
    • Hu, L.A.1    Chen, W.2    Premont, R.T.3    Cong, M.4    Lefkowitz, R.J.5
  • 38
    • 0038505967 scopus 로고    scopus 로고
    • GIPC interacts with the beta1-adrenergic receptor and regulates beta1-adrenergic receptor-mediated ERK activation
    • Hu L. A., Chen W., Martin N. P., Whalen E. J., Premont R. T. and Lefkowitz R. J. (2003) GIPC interacts with the beta1-adrenergic receptor and regulates beta1-adrenergic receptor-mediated ERK activation. J. Biol. Chem. 278, 26295-26301.
    • (2003) J. Biol. Chem. , vol.278 , pp. 26295-26301
    • Hu, L.A.1    Chen, W.2    Martin, N.P.3    Whalen, E.J.4    Premont, R.T.5    Lefkowitz, R.J.6
  • 39
    • 0016655517 scopus 로고
    • Glycogen and its related enzymes of metabolism in the central nervous system
    • Ibrahim M. Z. (1975) Glycogen and its related enzymes of metabolism in the central nervous system. Adv. Anat. Embryol. Cell Biol. 52, 3-89.
    • (1975) Adv. Anat. Embryol. Cell Biol. , vol.52 , pp. 3-89
    • Ibrahim, M.Z.1
  • 40
    • 0032489284 scopus 로고    scopus 로고
    • Tyrosine kinases of the Src family participate in signaling to MAP kinase from both Gq and Gi-coupled receptors
    • Igishi T. and Gutkind J. S. (1998) Tyrosine kinases of the Src family participate in signaling to MAP kinase from both Gq and Gi-coupled receptors. Biochem. Biophys. Res. Commun. 244, 5-10.
    • (1998) Biochem. Biophys. Res. Commun. , vol.244 , pp. 5-10
    • Igishi, T.1    Gutkind, J.S.2
  • 41
    • 0036315395 scopus 로고    scopus 로고
    • The UV (Ribotoxic) stress response of human keratinocytes involves the unexpected uncoupling of the Ras-extracellular signal-regulated kinase signaling cascade from the activated epidermal growth factor receptor
    • Iordanov M. S., Choi R. J., Ryabinina O. P., Dinh T. H., Bright R. K. and Magun B. E. (2002) The UV (Ribotoxic) stress response of human keratinocytes involves the unexpected uncoupling of the Ras-extracellular signal-regulated kinase signaling cascade from the activated epidermal growth factor receptor. Mol. Cell Biol. 22, 5380-5394.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 5380-5394
    • Iordanov, M.S.1    Choi, R.J.2    Ryabinina, O.P.3    Dinh, T.H.4    Bright, R.K.5    Magun, B.E.6
  • 42
    • 8744232106 scopus 로고    scopus 로고
    • Epac- and Ca2+-controlled activation of Ras and extracellular signal-regulated kinases by Gs-coupled receptors
    • Keiper M., Stope M. B. and Szatkowski D. et al. (2004) Epac- and Ca2+-controlled activation of Ras and extracellular signal-regulated kinases by Gs-coupled receptors. J. Biol. Chem. 279, 46497-46508.
    • (2004) J. Biol. Chem. , vol.279 , pp. 46497-46508
    • Keiper, M.1    Stope, M.B.2    Szatkowski, D.3
  • 43
    • 0027169565 scopus 로고
    • Protein kinase C activity is not involved in N-formylmethionyl-leucyl-phenylalanine-induced phospholipase D activation in human neutrophils, but is essential for concomitant NADPH oxidase activation: studies with a staurosporine analogue with improved selectivity for protein kinase C
    • Kessels G. C., Krause K. H. and Verhoeven A. J. (1993) Protein kinase C activity is not involved in N-formylmethionyl-leucyl-phenylalanine-induced phospholipase D activation in human neutrophils, but is essential for concomitant NADPH oxidase activation: studies with a staurosporine analogue with improved selectivity for protein kinase C. Biochem. J. 292, 781-785.
    • (1993) Biochem. J. , vol.292 , pp. 781-785
    • Kessels, G.C.1    Krause, K.H.2    Verhoeven, A.J.3
  • 44
    • 0037452949 scopus 로고    scopus 로고
    • Regulation of epidermal growth factor receptor internalization by G protein-coupled receptors
    • Kim J., Ahn S., Guo R. and Daaka Y. (2003) Regulation of epidermal growth factor receptor internalization by G protein-coupled receptors. Biochemistry 42, 2887-2894.
    • (2003) Biochemistry , vol.42 , pp. 2887-2894
    • Kim, J.1    Ahn, S.2    Guo, R.3    Daaka, Y.4
  • 45
    • 0018170087 scopus 로고
    • Enzymatic and morphological properties of primary rat brain astrocyte cultures, and enzyme development in vivo
    • Kimelberg H. K., Narumi S. and Bourke R. S. (1978) Enzymatic and morphological properties of primary rat brain astrocyte cultures, and enzyme development in vivo. Brain Res. 153, 55-77.
    • (1978) Brain Res. , vol.153 , pp. 55-77
    • Kimelberg, H.K.1    Narumi, S.2    Bourke, R.S.3
  • 46
    • 0027481032 scopus 로고
    • The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase
    • Koch W. J., Inglese J., Stone W. C. and Lefkowitz R. J. (1993) The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase. J. Biol. Chem. 268, 8256-8260.
    • (1993) J. Biol. Chem. , vol.268 , pp. 8256-8260
    • Koch, W.J.1    Inglese, J.2    Stone, W.C.3    Lefkowitz, R.J.4
  • 47
    • 0036129238 scopus 로고    scopus 로고
    • Up-regulation of 5-HT2B receptor density and receptor-mediated glycogenolysis in mouse astrocytes by long-term fluoxetine administration
    • Kong E. K. C., Peng L., Chen Y., Yu A. C. H. and Hertz L. (2002) Up-regulation of 5-HT2B receptor density and receptor-mediated glycogenolysis in mouse astrocytes by long-term fluoxetine administration. Neurochem. Int. 27, 113-120.
    • (2002) Neurochem. Int. , vol.27 , pp. 113-120
    • Kong, E.K.C.1    Peng, L.2    Chen, Y.3    Yu, A.C.H.4    Hertz, L.5
  • 49
    • 0032563291 scopus 로고    scopus 로고
    • G protein-coupled receptors. III New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization
    • Lefkowitz R. J. (1998) G protein-coupled receptors. III New roles for receptor kinases and beta-arrestins in receptor signaling and desensitization. J. Biol. Chem. 273, 18677-18680.
    • (1998) J. Biol. Chem. , vol.273 , pp. 18677-18680
    • Lefkowitz, R.J.1
  • 50
    • 56549103593 scopus 로고    scopus 로고
    • Fluoxetine-mediated 5-HT2B receptor stimulation in astrocytes causes EGF receptor transactivation and ERK phosphorylation
    • Li B., Zhang S., Zhang H., Nu W., Cai L., Hertz L. and Peng L. (2008a) Fluoxetine-mediated 5-HT2B receptor stimulation in astrocytes causes EGF receptor transactivation and ERK phosphorylation. Psychopharmacology (Berl) 201, 443-458.
    • (2008) Psychopharmacology (Berl) , vol.201 , pp. 443-458
    • Li, B.1    Zhang, S.2    Zhang, H.3    Nu, W.4    Cai, L.5    Hertz, L.6    Peng, L.7
  • 51
    • 42949120560 scopus 로고    scopus 로고
    • Signalling pathways for transactivation by dexmedetomidine of epidermal growth factor receptors in astrocytes and its paracrine effect on neurons
    • Li B., Du T., Li H., Gu L., Zhang H., Huang J., Hertz L. and Peng L. (2008b) Signalling pathways for transactivation by dexmedetomidine of epidermal growth factor receptors in astrocytes and its paracrine effect on neurons. Br. J. Pharmacol. 154, 191-203.
    • (2008) Br. J. Pharmacol. , vol.154 , pp. 191-203
    • Li, B.1    Du, T.2    Li, H.3    Gu, L.4    Zhang, H.5    Huang, J.6    Hertz, L.7    Peng, L.8
  • 52
    • 77958582482 scopus 로고    scopus 로고
    • Role of EGFR transactivation in dBcAMP induced morphological changes in astrocytes
    • Li H., Yang X. and Peng L. (2010) Role of EGFR transactivation in dBcAMP induced morphological changes in astrocytes. Zhong Guo Yi Ker Da Xue Xue Bao 39, 405-409.
    • (2010) Zhong Guo Yi Ker Da Xue Xue Bao , vol.39 , pp. 405-409
    • Li, H.1    Yang, X.2    Peng, L.3
  • 53
    • 61349130027 scopus 로고    scopus 로고
    • Deficiency of a beta-arrestin-2 signal complex contributes to insulin resistance
    • Luan B., Zhao J., Wu H., Duan B., Shu G., Wang X., Li D., Jia W., Kang J. and Pei G. (2009) Deficiency of a beta-arrestin-2 signal complex contributes to insulin resistance. Nature 457, 1146-1149.
    • (2009) Nature , vol.457 , pp. 1146-1149
    • Luan, B.1    Zhao, J.2    Wu, H.3    Duan, B.4    Shu, G.5    Wang, X.6    Li, D.7    Jia, W.8    Kang, J.9    Pei, G.10
  • 55
    • 0027442541 scopus 로고
    • Effects of selective antagonism of beta-adrenoceptor sub-types on responses to isoprenaline in rat distal colon in vitro
    • MacDonald A. and Lamont M. (1993) Effects of selective antagonism of beta-adrenoceptor sub-types on responses to isoprenaline in rat distal colon in vitro. Br. J. Pharmacol. 110, 1551-1555.
    • (1993) Br. J. Pharmacol. , vol.110 , pp. 1551-1555
    • MacDonald, A.1    Lamont, M.2
  • 56
    • 0020407826 scopus 로고
    • beta-Adrenergic receptors of brain cells. Membrane integrity implies apparent positive cooperativity and higher affinity
    • Maderspach K. and Fajszi C. (1982) beta-Adrenergic receptors of brain cells. Membrane integrity implies apparent positive cooperativity and higher affinity. Biochim. Biophys. Acta 692, 469-478.
    • (1982) Biochim. Biophys. Acta , vol.692 , pp. 469-478
    • Maderspach, K.1    Fajszi, C.2
  • 57
    • 0020709916 scopus 로고
    • Development of beta-adrenergic receptors and their function in glia-neuron communication in cultured chick brain
    • Maderspach K. and Fajszi C. (1983) Development of beta-adrenergic receptors and their function in glia-neuron communication in cultured chick brain. Brain Res. 282, 251-257.
    • (1983) Brain Res. , vol.282 , pp. 251-257
    • Maderspach, K.1    Fajszi, C.2
  • 58
    • 0034526574 scopus 로고    scopus 로고
    • Involvement of epidermal growth factor receptor in chemically induced mouse bladder tumour progression
    • Marjou A. E., Delouvée A., Thiery J. P. and Radvanyi F. (2000) Involvement of epidermal growth factor receptor in chemically induced mouse bladder tumour progression. Carcinogenesis 21, 2211-2218.
    • (2000) Carcinogenesis , vol.21 , pp. 2211-2218
    • Marjou, A.E.1    Delouvée, A.2    Thiery, J.P.3    Radvanyi, F.4
  • 59
    • 4644298923 scopus 로고    scopus 로고
    • PKA-mediated phosphorylation of the beta1-adrenergic receptor promotes Gs/Gi switching
    • Martin N. P., Whalen E. J., Zamah M. A., Pierce K. L. and Lefkowitz R. J. (2004) PKA-mediated phosphorylation of the beta1-adrenergic receptor promotes Gs/Gi switching. Cell. Signal. 16, 1397-1403.
    • (2004) Cell. Signal. , vol.16 , pp. 1397-1403
    • Martin, N.P.1    Whalen, E.J.2    Zamah, M.A.3    Pierce, K.L.4    Lefkowitz, R.J.5
  • 60
    • 0034737483 scopus 로고    scopus 로고
    • The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor
    • Maudsley S., Pierce K. L., Zamah A. M., Miller W. E., Ahn S., Daaka Y., Lefkowitz R. J. and Luttrell L. M. (2000) The beta(2)-adrenergic receptor mediates extracellular signal-regulated kinase activation via assembly of a multi-receptor complex with the epidermal growth factor receptor. J. Biol. Chem. 275, 9572-9580.
    • (2000) J. Biol. Chem. , vol.275 , pp. 9572-9580
    • Maudsley, S.1    Pierce, K.L.2    Zamah, A.M.3    Miller, W.E.4    Ahn, S.5    Daaka, Y.6    Lefkowitz, R.J.7    Luttrell, L.M.8
  • 61
    • 0025728092 scopus 로고
    • Neurotransmitters as developmental signals
    • Meier E., Hertz L. and Schousboe A. (1991) Neurotransmitters as developmental signals. Neurochem. Int. 19, 1-15.
    • (1991) Neurochem. Int. , vol.19 , pp. 1-15
    • Meier, E.1    Hertz, L.2    Schousboe, A.3
  • 62
    • 34249731075 scopus 로고    scopus 로고
    • Lipopolysaccharide stimulates Epac1-mediated Rap1/NF-kappaB pathway in Raw 264.7 murine macrophages
    • Moon E. Y. and Pyo S. (2007) Lipopolysaccharide stimulates Epac1-mediated Rap1/NF-kappaB pathway in Raw 264.7 murine macrophages. Immunol. Lett. 110, 121-125.
    • (2007) Immunol. Lett. , vol.110 , pp. 121-125
    • Moon, E.Y.1    Pyo, S.2
  • 63
    • 0021733711 scopus 로고
    • Pertussis toxin-catalyzed ADP-ribosylation: effects on the coupling of inhibitory receptors to the adenylate cyclase system
    • Moss J., Bruni P. and Hsia J. A. et al. (1984) Pertussis toxin-catalyzed ADP-ribosylation: effects on the coupling of inhibitory receptors to the adenylate cyclase system. J. Recept. Res. 4, 459-474.
    • (1984) J. Recept. Res. , vol.4 , pp. 459-474
    • Moss, J.1    Bruni, P.2    Hsia, J.A.3
  • 64
    • 0018227269 scopus 로고
    • Heterogeneity of cerebral beta-adrenoceptor binding sites in various vertebrate species
    • Nahorski S. R. (1978) Heterogeneity of cerebral beta-adrenoceptor binding sites in various vertebrate species. Eur. J. Pharmacol. 51, 199-209.
    • (1978) Eur. J. Pharmacol. , vol.51 , pp. 199-209
    • Nahorski, S.R.1
  • 65
    • 0018132936 scopus 로고
    • Effects of norepinephrine on the morphology and some enzyme activities of primary monolayer cultures from rat brain
    • Narumi S., Kimelberg H. K. and Bourke R. S. (1978) Effects of norepinephrine on the morphology and some enzyme activities of primary monolayer cultures from rat brain. J. Neurochem. 31, 1479-1490.
    • (1978) J. Neurochem. , vol.31 , pp. 1479-1490
    • Narumi, S.1    Kimelberg, H.K.2    Bourke, R.S.3
  • 66
    • 0348014544 scopus 로고    scopus 로고
    • Serine mutations that abrogate ligand-induced ubiquitination and internalization of the EGF receptor do not affect c-Cbl association with the receptor
    • Oksvold M. P., Thien C. B., Widerberg J., Chantry A., Huitfeldt H. S. and Langdon W. Y. (2003) Serine mutations that abrogate ligand-induced ubiquitination and internalization of the EGF receptor do not affect c-Cbl association with the receptor. Oncogene 22, 8509-8518.
    • (2003) Oncogene , vol.22 , pp. 8509-8518
    • Oksvold, M.P.1    Thien, C.B.2    Widerberg, J.3    Chantry, A.4    Huitfeldt, H.S.5    Langdon, W.Y.6
  • 67
    • 36148956500 scopus 로고    scopus 로고
    • Non-neuronal Cells of the Nervous System: Function and Dysfunction
    • Elsevier, Amsterdam.
    • Peng L. (2004) Transactivation in astrocytes as a novel mechanism of neuroprotection. in Non-neuronal Cells of the Nervous System: Function and Dysfunction (Hertz L., ed.), pp. 503-518. Elsevier, Amsterdam.
    • (2004) Transactivation in astrocytes as a novel mechanism of neuroprotection , pp. 503-518
    • Peng, L.1
  • 69
    • 0034652310 scopus 로고    scopus 로고
    • Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors
    • Pierce K. L., Maudsley S., Daaka Y., Luttrell L. M. and Lefkowitz R. J. (2000) Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors. Proc. Natl Acad. Sci. USA 97, 1489-1494.
    • (2000) Proc. Natl Acad. Sci. USA , vol.97 , pp. 1489-1494
    • Pierce, K.L.1    Maudsley, S.2    Daaka, Y.3    Luttrell, L.M.4    Lefkowitz, R.J.5
  • 70
    • 0035933814 scopus 로고    scopus 로고
    • Epidermal growth factor (EGF) receptor-dependent ERK activation by G protein-coupled receptors
    • Pierce K. L., Tohgo A., Ahn S., Field M. E., Luttrell L. M. and Lefkowitz R. J. (2001) Epidermal growth factor (EGF) receptor-dependent ERK activation by G protein-coupled receptors. J. Biol. Chem. 276, 23155-23160.
    • (2001) J. Biol. Chem. , vol.276 , pp. 23155-23160
    • Pierce, K.L.1    Tohgo, A.2    Ahn, S.3    Field, M.E.4    Luttrell, L.M.5    Lefkowitz, R.J.6
  • 71
    • 0037470136 scopus 로고    scopus 로고
    • Cholecystokinin stimulates extracellular signal-regulated kinase through activation of the epidermal growth factor receptor, Yes, and protein kinase C. Signal amplification at the level of Raf by activation of protein kinase Cepsilon
    • Piiper A., Elez R., You S. J., Kronenberger B., Loitsch S., Roche S. and Zeuzem S. (2003) Cholecystokinin stimulates extracellular signal-regulated kinase through activation of the epidermal growth factor receptor, Yes, and protein kinase C. Signal amplification at the level of Raf by activation of protein kinase Cepsilon. J. Biol. Chem. 278, 7065-7072.
    • (2003) J. Biol. Chem. , vol.278 , pp. 7065-7072
    • Piiper, A.1    Elez, R.2    You, S.J.3    Kronenberger, B.4    Loitsch, S.5    Roche, S.6    Zeuzem, S.7
  • 72
    • 0034992521 scopus 로고    scopus 로고
    • The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification
    • Prenzel N., Fischer O. M., Streit S., Hart S. and Ullrich A. (2001) The epidermal growth factor receptor family as a central element for cellular signal transduction and diversification. Endocr. Relat. Cancer 8, 11-31.
    • (2001) Endocr. Relat. Cancer , vol.8 , pp. 11-31
    • Prenzel, N.1    Fischer, O.M.2    Streit, S.3    Hart, S.4    Ullrich, A.5
  • 73
    • 4344683428 scopus 로고    scopus 로고
    • Differential activation of epidermal growth factor (EGF) receptor downstream signaling pathways by betacellulin and EGF
    • Saito T., Okada S., Ohshima K., Yamada E., Sato M., Uehara Y., Shimizu H., Pessin J. E. and Mori M. (2004) Differential activation of epidermal growth factor (EGF) receptor downstream signaling pathways by betacellulin and EGF. Endocrinology 145, 4232-4243.
    • (2004) Endocrinology , vol.145 , pp. 4232-4243
    • Saito, T.1    Okada, S.2    Ohshima, K.3    Yamada, E.4    Sato, M.5    Uehara, Y.6    Shimizu, H.7    Pessin, J.E.8    Mori, M.9
  • 74
    • 40849139148 scopus 로고    scopus 로고
    • TGF-beta1-induced plasminogen activator inhibitor-1 expression in vascular smooth muscle cells requires pp60(c-src)/EGFR(Y845) and Rho/ROCK signaling
    • Samarakoon R., Higgins S. P., Higgins C. E. and Higgins P. J. (2008) TGF-beta1-induced plasminogen activator inhibitor-1 expression in vascular smooth muscle cells requires pp60(c-src)/EGFR(Y845) and Rho/ROCK signaling. J. Mol. Cell Cardiol. 44, 527-538.
    • (2008) J. Mol. Cell Cardiol. , vol.44 , pp. 527-538
    • Samarakoon, R.1    Higgins, S.P.2    Higgins, C.E.3    Higgins, P.J.4
  • 75
    • 0035917312 scopus 로고    scopus 로고
    • Relationships between beta- and alpha2-adrenoceptors and G coupling proteins in the human brain: effects of age and suicide
    • Sastre M., Guimón J. and García-Sevilla J. A. (2001) Relationships between beta- and alpha2-adrenoceptors and G coupling proteins in the human brain: effects of age and suicide. Brain Res. 898, 242-255.
    • (2001) Brain Res. , vol.898 , pp. 242-255
    • Sastre, M.1    Guimón, J.2    García-Sevilla, J.A.3
  • 76
    • 0037088597 scopus 로고    scopus 로고
    • AT1 receptor mutant lacking heterotrimeric G protein coupling activates the Src-Ras-ERK pathway without nuclear translocation of ERKs
    • Seta K., Nanamori M., Modrall J. G., Neubig R. R. and Sadoshima J.. (2002) AT1 receptor mutant lacking heterotrimeric G protein coupling activates the Src-Ras-ERK pathway without nuclear translocation of ERKs. J. Biol. Chem. 277, 9268-9277.
    • (2002) J. Biol. Chem. , vol.277 , pp. 9268-9277
    • Seta, K.1    Nanamori, M.2    Modrall, J.G.3    Neubig, R.R.4    Sadoshima, J.5
  • 77
    • 33644857279 scopus 로고    scopus 로고
    • beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor
    • Shenoy S. K., Drake M. T. and Nelson C. D. et al. (2006) beta-arrestin-dependent, G protein-independent ERK1/2 activation by the beta2 adrenergic receptor. J. Biol. Chem. 281, 1261-1273.
    • (2006) J. Biol. Chem. , vol.281 , pp. 1261-1273
    • Shenoy, S.K.1    Drake, M.T.2    Nelson, C.D.3
  • 78
    • 0025950483 scopus 로고
    • Characterization of the glycogenolysis elicited by vasoactive intestinal peptide, noradrenaline and adenosine in primary cultures of mouse cerebral cortical astrocytes
    • Sorg O. and Magistretti P. J. (1991) Characterization of the glycogenolysis elicited by vasoactive intestinal peptide, noradrenaline and adenosine in primary cultures of mouse cerebral cortical astrocytes. Brain Res. 563, 227-233.
    • (1991) Brain Res. , vol.563 , pp. 227-233
    • Sorg, O.1    Magistretti, P.J.2
  • 79
    • 0026687216 scopus 로고
    • Multiple autophosphorylation sites of the epidermal growth factor receptor are essential for receptor kinase activity and internalization. Contrasting significance of tyrosine 992 in the native and truncated receptors
    • Sorkin A., Helin K., Waters C. M., Carpenter G. and Beguinot L. (1992) Multiple autophosphorylation sites of the epidermal growth factor receptor are essential for receptor kinase activity and internalization. Contrasting significance of tyrosine 992 in the native and truncated receptors. J. Biol. Chem. 267, 8672-8678.
    • (1992) J. Biol. Chem. , vol.267 , pp. 8672-8678
    • Sorkin, A.1    Helin, K.2    Waters, C.M.3    Carpenter, G.4    Beguinot, L.5
  • 80
    • 0030919893 scopus 로고    scopus 로고
    • Activation of c-Raf-1 by Ras and Src through different mechanisms: activation in vivo and in vitro
    • Stokoe D. and McCormick F. (1997) Activation of c-Raf-1 by Ras and Src through different mechanisms: activation in vivo and in vitro. EMBO J. 16, 2384-2396.
    • (1997) EMBO J. , vol.16 , pp. 2384-2396
    • Stokoe, D.1    McCormick, F.2
  • 82
    • 36148944785 scopus 로고
    • When a G protein-coupled receptor does not couple to a G protein
    • Sun Y., McGarrigle D. and Huang X. Y. (1975) When a G protein-coupled receptor does not couple to a G protein. Mol. Biosyst. 3, 849-854.
    • (1975) Mol. Biosyst. , vol.3 , pp. 849-854
    • Sun, Y.1    McGarrigle, D.2    Huang, X.Y.3
  • 84
    • 21544435993 scopus 로고    scopus 로고
    • Insights into regulation of human Schwann cell proliferation by Erk1/2 via a MEK-independent and p56Lck-dependent pathway from leprosy bacilli
    • Tapinos N. and Rambukkana A. (2005) Insights into regulation of human Schwann cell proliferation by Erk1/2 via a MEK-independent and p56Lck-dependent pathway from leprosy bacilli. Proc. Natl Acad. Sci. USA 102, 9188-9193.
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 9188-9193
    • Tapinos, N.1    Rambukkana, A.2
  • 85
    • 0033573921 scopus 로고    scopus 로고
    • Mechanism of biological synergy between cellular Src and epidermal growth factor receptor
    • Tice D. A., Biscardi J. S., Nickles A. L. and Parsons S. J. (1999) Mechanism of biological synergy between cellular Src and epidermal growth factor receptor. Proc. Natl Acad. Sci. USA 96, 1415-1420.
    • (1999) Proc. Natl Acad. Sci. USA , vol.96 , pp. 1415-1420
    • Tice, D.A.1    Biscardi, J.S.2    Nickles, A.L.3    Parsons, S.J.4
  • 86
    • 0030461226 scopus 로고    scopus 로고
    • Control of EGF receptor signaling by clathrin-mediated endocytosis
    • Vieira A. V., Lamaze C. and Schmid S. L. (1996) Control of EGF receptor signaling by clathrin-mediated endocytosis. Science 274, 2086-2089.
    • (1996) Science , vol.274 , pp. 2086-2089
    • Vieira, A.V.1    Lamaze, C.2    Schmid, S.L.3
  • 87
    • 0029958903 scopus 로고    scopus 로고
    • Systematic mapping of potential binding sites for Shc and Grb2 SH2 domains on insulin receptor substrate-1 and the receptors for insulin, epidermal growth factor, platelet-derived growth factor, and fibroblast growth factor
    • Ward C. W., Gough K. H., Rashke M., Wan S. S., Tribbick G. and Wang J. (1996) Systematic mapping of potential binding sites for Shc and Grb2 SH2 domains on insulin receptor substrate-1 and the receptors for insulin, epidermal growth factor, platelet-derived growth factor, and fibroblast growth factor. J. Biol. Chem. 271, 5603-5609.
    • (1996) J. Biol. Chem. , vol.271 , pp. 5603-5609
    • Ward, C.W.1    Gough, K.H.2    Rashke, M.3    Wan, S.S.4    Tribbick, G.5    Wang, J.6
  • 88
    • 0037025389 scopus 로고    scopus 로고
    • Src-dependent phosphorylation of the epidermal growth factor receptor on tyrosine 845 is required for zinc-induced Ras activation
    • Wu W., Graves L. M., Gill G. N., Parsons S. J. and Samet J. M. (2002) Src-dependent phosphorylation of the epidermal growth factor receptor on tyrosine 845 is required for zinc-induced Ras activation. J. Biol. Chem. 277, 24252-24257.
    • (2002) J. Biol. Chem. , vol.277 , pp. 24252-24257
    • Wu, W.1    Graves, L.M.2    Gill, G.N.3    Parsons, S.J.4    Samet, J.M.5
  • 90
    • 19644384751 scopus 로고    scopus 로고
    • beta-Adrenergic-responsive activation of extracellular signal-regulated protein kinases in salivary cells: role of epidermal growth factor receptor and cAMP
    • Yeh C. K., Ghosh P. M., Dang H., Liu Q., Lin A. L., Zhang B. X. and Katz M. S. (2005) beta-Adrenergic-responsive activation of extracellular signal-regulated protein kinases in salivary cells: role of epidermal growth factor receptor and cAMP. Am. J. Physiol. Cell Physiol. 288, C1357-C1366.
    • (2005) Am. J. Physiol. Cell Physiol. , vol.288
    • Yeh, C.K.1    Ghosh, P.M.2    Dang, H.3    Liu, Q.4    Lin, A.L.5    Zhang, B.X.6    Katz, M.S.7
  • 91
    • 0037163048 scopus 로고    scopus 로고
    • Protein kinase A-mediated phosphorylation of the beta 2-adrenergic receptor regulates its coupling to Gs and Gi. Demonstration in a reconstituted system
    • Zamah A. M., Delahunty M., Luttrell L. M. and Lefkowitz R. J. (2002) Protein kinase A-mediated phosphorylation of the beta 2-adrenergic receptor regulates its coupling to Gs and Gi. Demonstration in a reconstituted system. J. Biol. Chem. 277, 31249-31256.
    • (2002) J. Biol. Chem. , vol.277 , pp. 31249-31256
    • Zamah, A.M.1    Delahunty, M.2    Luttrell, L.M.3    Lefkowitz, R.J.4
  • 92
    • 0029934037 scopus 로고    scopus 로고
    • Effects of benzodiazepines on potassium-induced increase in free cytosolic calcium concentration in astrocytes: interactions with nifedipine and the peripheral-type benzodiazepine antagonist PK 11195
    • Zhao Z., Hertz L. and Code W. E. (1996) Effects of benzodiazepines on potassium-induced increase in free cytosolic calcium concentration in astrocytes: interactions with nifedipine and the peripheral-type benzodiazepine antagonist PK 11195. Can. J. Physiol. Pharmacol. 74, 273-277.
    • (1996) Can. J. Physiol. Pharmacol. , vol.74 , pp. 273-277
    • Zhao, Z.1    Hertz, L.2    Code, W.E.3
  • 94
    • 0033515118 scopus 로고    scopus 로고
    • Both Gs and Gi proteins are critically involved in isoproterenol-induced cardiomyocyte hypertrophy
    • Zou Y., Komuro I., Yamazaki T., Kudoh S., Uozumi H., Kadowaki T. and Yazaki Y. (1999) Both Gs and Gi proteins are critically involved in isoproterenol-induced cardiomyocyte hypertrophy. J. Biol. Chem. 274, 9760-9770.
    • (1999) J. Biol. Chem. , vol.274 , pp. 9760-9770
    • Zou, Y.1    Komuro, I.2    Yamazaki, T.3    Kudoh, S.4    Uozumi, H.5    Kadowaki, T.6    Yazaki, Y.7
  • 95
    • 0030770603 scopus 로고    scopus 로고
    • Critical role of calcium- dependent epidermal growth factor receptor transactivation in PC12 cell membrane depolarization and bradykinin signaling
    • Zwick E., Daub H., Aoki N., Yamaguchi-Aoki Y., Tinhofer I., Maly K. and Ullrich A. (1997) Critical role of calcium- dependent epidermal growth factor receptor transactivation in PC12 cell membrane depolarization and bradykinin signaling. J. Biol. Chem. 272, 24767-24770.
    • (1997) J. Biol. Chem. , vol.272 , pp. 24767-24770
    • Zwick, E.1    Daub, H.2    Aoki, N.3    Yamaguchi-Aoki, Y.4    Tinhofer, I.5    Maly, K.6    Ullrich, A.7


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