Pharmacological and developmental evidence that the potassium-induced stimulation of deoxyglucose uptake in astrocytes is a metabolic manifestation of increased na+-k+-atpase activity

Developmental Neuroscience

Volumn 18, Issue 5-6, 1996, Pages 353-359

  Peng, Liang ^a   Jiturlink, Bernhard H J ^b  

^a Departments of Pharmacology and Anatomy   (Canada)

^b UNIVERSITY OF SASKATCHEWAN   (Canada)

Author keywords

Astrocyte; Deoxyglucose uptake; Differentiation; Ouabain; Potassium

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); DEOXYGLUCOSE; ENZYME INHIBITOR; OUABAIN; POTASSIUM ION;

ANIMAL CELL; ASTROCYTE; BINDING AFFINITY; CELL MATURATION; CONFERENCE PAPER; CONTROLLED STUDY; DRUG ACCUMULATION; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME STRUCTURE; GLYCOLYSIS; NERVE CELL CULTURE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; RAT;

ANIMALS; ASTROCYTES; DEOXYGLUCOSE; ENZYME INHIBITORS; MICE; NA(+)-K(+)-EXCHANGING ATPASE; OSMOLAR CONCENTRATION; OUABAIN; POTASSIUM; RATS;

EID: 0029910492     PISSN: 03785866     EISSN: 14219859     Source Type: Journal    
DOI: 10.1159/000111428     Document Type: Article

References (48)

1. Men L: Neuroglial-neuronal impulse transmission system. Nature 1965:206:1091-1094.
2. Orkand RK, Nicliolls JG. Kufflcr SW: Effect of nerve impulses on the membrane potential of glial cells in the central nervous system of amphibia. J Neurophysiol 1966;29:788-806.
3. Walz VV. Hertz L: Functional interactions between neurons and astrocytes II. Prog Ncu-robiol 1983:20:133-183.
4. Sykova E: Extracellular K' accumulation in the central nervous system. Prog Biophys 1983:42:135-189.
5. Dietzel L. Hcincmann U. Lux HI: Relations between slow extracellular potential changes, glial potassium buffering, and electrolyte and cellular volume changes during neuronal hyperactivity. Glia 1989:2:25-44.
6. Grafe P. Ballanyi K: Cellular mechanisms of potassium homeostasis in the mammalian nervous system. Can J Physiol Pharmacol 1987; 65:1038-1042.
7. Newman E: Glial cell regulation of extracellular potassium; in Kettenman H. Ransom BR (eds): Neuroglia. New York. Plenum Press. 1995. pp 717-731.
8. Skou JC: Preparations from mammalian brain and kidney of the enzyme system involved in active transport of Na-and K\ Biochim Biophys Acta 1962:58:314-325.
9. Sweadncr KJ: Na-K-ATPasc and its isofonns; in Kellenmann II. Ransom BR (cds): Neuroglia. New York. Plenum Press. 1995. pp 259-272.
10. Grisar T. Frere JM. Franck G: Effects of K" ions on kinetic properties of the Na'-K’l-ATPase (EC 3.6.1.3.) of bulk isolated glia cells, perikarya and synaptosomes from rabbit brain cortex. Brain Res 1979:165:87-103.
11. Moonen G. Franck G. Schoffenicls E: Glial control of neuronal excitability in mammals. I. Elcctrophysiological and isotopic evidence in culture. Ncurochem lnt 1980:2:299-310.
12. Mercado R. Hernandez J: Regulatory role of a neurotransmitter (5-HT) on glial Na'-K(’)-ATPasc in the rat brain. Ncurochem lnt 1992: 21:119-127.
13. Hajek I. Subbarao KVS. Hertz L: Acute and chronic effects of potassium and noradrenaline on Na’-K’-ATPasc activity in cultured mouse neurons and astrocytes. Neurochcm lnt. in press.
14. Reichcnbach A: K‘ion regulation in retina. Can J Physiol Pharmacol 1992;70:S239-S247.
15. Whiltam R: The dependence of the respiration of brain cortex on active cation transport. Bio-chemJ 1962:82:205-212.
16. Kadekaro M. Crane AM. Sokoloff L: Differential effects of electrical stimulation of sciatic nerve on metabolic activity in spinal cord and dorsal root ganglion in the rat. Proc Natl Acad SciUSA 1985:82:6010-6013.
17. Peng L, Zhang X, Hertz L: High extracellular potassium concentrations stimulate oxidative metabolism in cerebellar granule cells and glycolysis in astrocytes, but have no stimulatory effect in cerebral cortical neurons. Brain Res 1994;663:168-172.
18. Takahashi S. Driscoll BF. Law MJ. Sokoloff L: Role of sodium and potassium ions in regulation of glucose metabolism in cultured astroglia. Proc Natl Acad Sci USA 1995:92:4616-4620.
19. Sokoloff L. Rcivich M. Kennedy C. dcs Rosiers MH, Patlak CS, Pettigrew KD, Saku-rada O. Shinohara M: The f'Cldeoxyglucosc method for the measurement of local cerebral glucose utilization: Theory, procedure and normal values in the conscious and anesthetized albino rat. J Neurochcm 1977:28:897-916.
20. Pellerin L, Magistretti PJ: Glutamate uptake into astrocytes stimulates aerobic glycolysis: A mechanism coupling neuronal activity to glucose utilization. Proc Nall Acad Sci USA 1994; 91:10625-10629.
21. Cummins CJ, Glover RA, Sellinger OZ: Astroglial uptake is modulated by extracellular K\J Neurochem 1979:33:779-785.
22. Samson FE, Quinn DJ: Na'-Reactivated ATPase in rat brain development. J Neurochem 1967:14:421-427.
23. Lai JC, Leung TK, Lim L. Chan AW. Minsk! MJ: Effect of chronic manganese treatment on rat brain regional sodium-potassium-aclivated and magnesium-activated adenosine triphosphatase activities during development. Metab Brain Dis 1991:6:165-174.
24. Corthcsy-Theulaz I, Mcrillat AM. Honegger P. Rossier BC: NaC-K(‘)-ATPase gene expression during in vitro development of rat fetal forcbrain. Am J Physiol 1990:258:0062-0069.
25. Sweadner KJ. Tang P, Arystarkhova EA. Peng L: Na-K-ATPase j subunit absence in astrocytes and C6 glioma. Soc Ncurosci (abstracts) 1995:21:583.
26. Marks MJ, Seeds NW: Ouabain-ATPase interaction in brain cells maintained as re-aggregates of surface cultures. Life Sci 1978:23: 2745-2756.
27. Hertz L. Juurlink BHJ, Szuchet S: Cell cultures; in Lajtha A (ed); Handbook of Neuro-chemistry. cd 2. New York, Plenum Press, 1985, vol 8, pp 603-661.
28. Hertz L. Juurlink BHJ. Hertz E. Fosmark H. Schousboe A: Preparation of primary cultures of mouse (rat) astrocytes; In Shahar A. dc Vel-lis J. Vcmadakis A, Haber B (eds); A Dissection and Tissue Culture Manual of the Nervous System. New York, Liss, 1989, pp. 105-108.
29. Juurlink BHJ. Hertz L: Astrocytes; In Boulton AA, Baker GB. Walz W (eds); Neuromethods. New York, Humana Clifton. 1992. vol 23. pp 269-321.
30. Hertz L; Dibutyryl cyclic AMP treatment of astrocytes in primary cultures as a substitute for normal morphogenic and ‘functiogenic’ transmitter signals; in Privat A, Giacobini E. Timiras P, Vemadakis A (eds); Molecular Aspects of Development and Aging in the Nervous System. New York, Plenum Press, 1982. pp 227-243.
31. Meier E, Hertz L, Schousboe A: Ncurotrans-mitters as developmental signals. Neurochem lnt 1991:19:1-15.
32. Wiesinger H, Schurich B, Hamprecht B: Replacement of glucose by sorbitol in growth medium causes selection of astroglia from heterogeneous primary cultures derived from mouse brain. Brain Res 1991:550:69-76.
33. Lowry OH, Roscbrough NJ, Farr AL. Randall RJ: Protein measurement with the Folirt phenol reagent. J Biol Chem 1951:193:265-275.
34. Dicnel GA. Cruz NF, Mori K. Holden JE. Sokoloff L: Direct measurement of the X of the lumped constant of the dcoxyglucosc method in rat brain: Determination of X and lumped constant from tissue glucose concentration or equilibrium brain/plasma distribution ratio for meihylglucose. J Ccreb Blood Flow Metab 1991:11:25-34.
35. Edmond J, Aucstad N. Robbins RA, Bergstrom JD: Ketone body metabolism in the neonate: Development and the effect of diet. Fed Proc 1985:44:2359-2364.
36. Lopes-Cardozo M, Larsson OM, Schousboe A: Acetoacetate and glucose as lipid precursor and energy substrates in primary cultures of astrocytes and neurons from mouse cerebral cortex. J Neurochem 1986:46:773-778.
37. Hertz L. Drcjer J. Schousboe A: Energy metabolism in glutamatergic neurons. GABAcrgic neurons and astrocytes in primary' cultures. Neurochem Res 1988;13:605-610.
38. Brookes N, Yarowsky PJ: Determinants of dcoxyglucosc uptake in cultured astrocytes: The role of the sodium pump. J Ncurochem 1985:44:473-479.
39. Walz W, Mukcrji S: Lactate release from cultured astrocytes and neurons: A comparison. Glia 1988:1:366-370.
40. Yu ACH. Shargoo! M, Hertz E. Lee YL. Eng LF. Hertz L: K‘/hypoxia effect on pyruvate/lactate in astrocytes. Trans Soc Am Soc Neurochem 1990:21:155.
41. Rose CR. Ransom BR: Fluorescence imaging of intracellular sodium in rat hippocampal astrocytes. Soc Neurosci (abstracts) 1995:21: 1995.
42. Hertz L. Bock E. Schousboe A: GFA content, glutamate uptake and activity of glutamate metabolizing enzymes in differentiating mouse astrocytes in primary cultures. Dev Neurosci 1978:1:226-238.
43. Schousboe A. Nissen C. Bock E, Sapirstein V. Juurlink BHJ. Hertz L: Biochemical development of rodent astrocytes in primary' cultures; in Giacobini E, Vemadakis A. Shahar A (eds); Tissue Culture in Ncurobiology. New York. Raven Press, 1980, pp 397-409.
44. Sykova E: Ionic and Volume Changes in the Microenvironment of Nerve and Receptor Cells. Prog Sens Physiol. New York. Springer. 1992. vol 13.
45. McGrail KM, Sweadner KJ: Complex expression patterns for Na-K-ATPase isoforms in retina and optic nerve. Eur J Neurosci 1989: 2:170-176.
46. McGrail KM. Phillips JM. Sweadner KJ: Immunofluorescem localization of three Na-K-ATPase isozymes in the rat central nervous system: Both neurons and glia can express more than one Na-K-ATPase. J Neurosci 1991; 11:381-391.
47. Peng L, McGrail KM, Sweadner KJ: Isoforms of Na-K-ATPase subunits in the rat cerebellum and in granule cell cultures. Submitted.
48. Alterwill CK. Cunningham VJ. Balazs R: Characterization of Na'-K'-ATPase in cultured and separated neuronal and glial cells from rat cerebellum. J Neurochcm I984;43: 8-18.