-
1
-
-
84872091789
-
Heart disease and stroke statistics: 2013 update - A report from the American Heart Association
-
Go AS, Mozaffarian D, Roger VL, et al. Heart disease and stroke statistics: 2013 update -a report from the American Heart Association. Circulation 2013; 127:e6-e245.
-
(2013)
Circulation
, vol.127
-
-
Go, A.S.1
Mozaffarian, D.2
Roger, V.L.3
-
3
-
-
0242361644
-
Body mass index: A risk factor for unstable angina and myocardial infarction in patients with angiographically confirmed coronary artery disease
-
Wolk R, Berger P, Lennon RJ, et al. Body mass index: a risk factor for unstable angina and myocardial infarction in patients with angiographically confirmed coronary artery disease. Circulation 2003; 108:2206-2211.
-
(2003)
Circulation
, vol.108
, pp. 2206-2211
-
-
Wolk, R.1
Berger, P.2
Lennon, R.J.3
-
4
-
-
27644457743
-
Obesity and the risk of myocardial infarction in 27 000 participants from 52 countries: A case-control study
-
Yusuf S, Hawken S, Ounpuu S, et al. Obesity and the risk of myocardial infarction in 27 000 participants from 52 countries: a case-control study. Lancet 2005; 366:1640-1649.
-
(2005)
Lancet
, vol.366
, pp. 1640-1649
-
-
Yusuf, S.1
Hawken, S.2
Ounpuu, S.3
-
5
-
-
0031009871
-
A prospective study of body mass index, weight change, and risk of stroke in women
-
Rexrode KM, Hennekens CH, Willett WC, et al. A prospective study of body mass index, weight change, and risk of stroke in women. JAMA 1997; 277:1539-1545.
-
(1997)
JAMA
, vol.277
, pp. 1539-1545
-
-
Rexrode, K.M.1
Hennekens, C.H.2
Willett, W.C.3
-
6
-
-
0038152801
-
Abdominal obesity and risk of ischemic stroke: The Northern Manhattan Stroke Study
-
Suk SH, Sacco RL, Boden-Albala B, et al. Abdominal obesity and risk of ischemic stroke: the Northern Manhattan Stroke Study. Stroke 2003; 34: 1586-1592.
-
(2003)
Stroke
, vol.34
, pp. 1586-1592
-
-
Suk, S.H.1
Sacco, R.L.2
Boden-Albala, B.3
-
7
-
-
24744470476
-
Obesity as a risk factor in venous thromboembolism
-
Stein PD, Beemath A, Olson RE. Obesity as a risk factor in venous thromboembolism. Am J Med 2005; 118:978-980.
-
(2005)
Am J Med
, vol.118
, pp. 978-980
-
-
Stein, P.D.1
Beemath, A.2
Olson, R.E.3
-
8
-
-
84859766500
-
Body mass index, surgery, and risk of venous thromboembolism in middle-aged women: A cohort study
-
Parkin L, Sweetland S, Balkwill A, et al. Body mass index, surgery, and risk of venous thromboembolism in middle-aged women: a cohort study. Circulation 2012; 125:1897-1904.
-
(2012)
Circulation
, vol.125
, pp. 1897-1904
-
-
Parkin, L.1
Sweetland, S.2
Balkwill, A.3
-
9
-
-
84872327440
-
Pathophysiology of human visceral obesity: An update
-
Tchernof A, Despres JP. Pathophysiology of human visceral obesity: an update. Physiol Rev 2013; 93:359-404.
-
(2013)
Physiol Rev
, vol.93
, pp. 359-404
-
-
Tchernof, A.1
Despres, J.P.2
-
10
-
-
79751512463
-
The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance
-
Vandanmagsar B, Youm YH, Ravussin A, et al. The NLRP3 inflammasome instigates obesity-induced inflammation and insulin resistance. Nat Med 2011; 17:179-188.
-
(2011)
Nat Med
, vol.17
, pp. 179-188
-
-
Vandanmagsar, B.1
Youm, Y.H.2
Ravussin, A.3
-
11
-
-
84872142459
-
JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation
-
Han MS, Jung DY, Morel C, et al. JNK expression by macrophages promotes obesity-induced insulin resistance and inflammation. Science 2013; 339: 218-222.
-
(2013)
Science
, vol.339
, pp. 218-222
-
-
Han, M.S.1
Jung, D.Y.2
Morel, C.3
-
12
-
-
33745216724
-
MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity
-
Kanda H, Tateya S, Tamori Y, et al. MCP-1 contributes to macrophage infiltration into adipose tissue, insulin resistance, and hepatic steatosis in obesity. J Clin Invest 2006; 116:1494-1505.
-
(2006)
J Clin Invest
, vol.116
, pp. 1494-1505
-
-
Kanda, H.1
Tateya, S.2
Tamori, Y.3
-
13
-
-
77955404414
-
The role of adipose tissue and adipokines in obesity-related inflammatory diseases
-
Balistreri CR, Caruso C, Candore G. The role of adipose tissue and adipokines in obesity-related inflammatory diseases. Mediators Inflamm 2010; 2010:802078.
-
(2010)
Mediators Inflamm
, vol.2010
, pp. 802078
-
-
Balistreri, C.R.1
Caruso, C.2
Candore, G.3
-
14
-
-
33845914986
-
Mechanisms linking obesity with cardiovascular disease
-
Van Gaal LF, Mertens IL, De Block CE. Mechanisms linking obesity with cardiovascular disease. Nature 2006; 444:875-880.
-
(2006)
Nature
, vol.444
, pp. 875-880
-
-
Van Gaal, L.F.1
Mertens, I.L.2
De Block, C.E.3
-
15
-
-
84863085792
-
Infection and inflammation as risk factors for thrombosis and atherosclerosis
-
Levi M, van der Poll T, Schultz M. Infection and inflammation as risk factors for thrombosis and atherosclerosis. Semin Thromb Hemost 2012; 38:506-514.
-
(2012)
Semin Thromb Hemost
, vol.38
, pp. 506-514
-
-
Levi, M.1
Van Der Poll, T.2
Schultz, M.3
-
17
-
-
0032540243
-
Comparison of promoters for the murine and human P-selectin genes suggests species-specific and conserved mechanisms for transcriptional regulation in endothelial cells
-
Pan J, Xia L, McEver RP. Comparison of promoters for the murine and human P-selectin genes suggests species-specific and conserved mechanisms for transcriptional regulation in endothelial cells. J Biol Chem 1998; 273:10058-10067.
-
(1998)
J Biol Chem
, vol.273
, pp. 10058-10067
-
-
Pan, J.1
Xia, L.2
McEver, R.P.3
-
18
-
-
77954763055
-
Relation of platelet and leukocyte inflammatory transcripts to body mass index in the Framingham Heart Study
-
Freedman JE, LarsonMG, Tanriverdi K, et al. Relation of platelet and leukocyte inflammatory transcripts to body mass index in the Framingham Heart Study. Circulation 2010; 122:119-129.
-
(2010)
Circulation
, vol.122
, pp. 119-129
-
-
Freedman, J.E.1
Larson, M.G.2
Tanriverdi, K.3
-
21
-
-
15844381594
-
Enhanced expression of PAI-1 in visceral fat: Possible contributor to vascular disease in obesity
-
Shimomura I, Funahashi T, Takahashi M, et al. Enhanced expression of PAI-1 in visceral fat: possible contributor to vascular disease in obesity. Nat Med 1996; 2:800-803.
-
(1996)
Nat Med
, vol.2
, pp. 800-803
-
-
Shimomura, I.1
Funahashi, T.2
Takahashi, M.3
-
23
-
-
80052304526
-
Association of vitronectin and plasminogen activator inhibitor-1 levels with the risk of metabolic syndrome and type 2 diabetes mellitus. Results from the D.E.S.I. R. prospective cohort
-
Alessi MC, Nicaud V, Scroyen I, et al. Association of vitronectin and plasminogen activator inhibitor-1 levels with the risk of metabolic syndrome and type 2 diabetes mellitus. Results from the D.E.S.I. R. prospective cohort. Thromb Haemost 2011; 106:416-422.
-
(2011)
Thromb Haemost
, vol.106
, pp. 416-422
-
-
Alessi, M.C.1
Nicaud, V.2
Scroyen, I.3
-
24
-
-
79959729276
-
Metabolic factors, adipose tissue, and plasminogen activator inhibitor-1 levels in type 2 diabetes: Findings from the look AHEAD study
-
Belalcazar LM, Ballantyne CM, Lang W, et al. Metabolic factors, adipose tissue, and plasminogen activator inhibitor-1 levels in type 2 diabetes: findings from the look AHEAD study. Arterioscler Thromb Vasc Biol 2011; 31:1689-1695.
-
(2011)
Arterioscler Thromb Vasc Biol
, vol.31
, pp. 1689-1695
-
-
Belalcazar, L.M.1
Ballantyne, C.M.2
Lang, W.3
-
25
-
-
84864304198
-
Elevated circulating tissue factor procoagulant activity, factor VII, and plasminogen activator inhibitor-1 in childhood obesity: Evidence of a procoagulant state
-
Singh A, Foster GD, Gunawardana J, et al. Elevated circulating tissue factor procoagulant activity, factor VII, and plasminogen activator inhibitor-1 in childhood obesity: evidence of a procoagulant state. Br J Haematol 2012; 158:523-527.
-
(2012)
Br J Haematol
, vol.158
, pp. 523-527
-
-
Singh, A.1
Foster, G.D.2
Gunawardana, J.3
-
26
-
-
0030050952
-
Distribution and regulation of plasminogen activator inhibitor-1 in murine adipose tissue in vivo. Induction by tumor necrosis factor-alpha and lipopolysaccharide
-
Samad F, Yamamoto K, Loskutoff DJ. Distribution and regulation of plasminogen activator inhibitor-1 in murine adipose tissue in vivo. Induction by tumor necrosis factor-alpha and lipopolysaccharide. J Clin Invest 1996; 97:37-46.
-
(1996)
J Clin Invest
, vol.97
, pp. 37-46
-
-
Samad, F.1
Yamamoto, K.2
Loskutoff, D.J.3
-
27
-
-
62249216404
-
Role of fibrinolysis in obesity and thrombosis
-
Lijnen HR. Role of fibrinolysis in obesity and thrombosis. Thromb Res 2009; 123 (Suppl 4):S46-S49.
-
(2009)
Thromb Res
, vol.123
, Issue.SUPPL. 4
-
-
Lijnen, H.R.1
-
28
-
-
0029827134
-
Tissue distribution and regulation of plasminogen activator inhibitor-1 in obese mice
-
Samad F, Loskutoff DJ. Tissue distribution and regulation of plasminogen activator inhibitor-1 in obese mice. Mol Med 1996; 2:568-582.
-
(1996)
Mol Med
, vol.2
, pp. 568-582
-
-
Samad, F.1
Loskutoff, D.J.2
-
29
-
-
34447640693
-
Plasminogen activator inhibitor-1 contributes to the deleterious effect of obesity on the outcome of thrombotic ischemic stroke in mice
-
Nagai N, Van Hoef B, Lijnen HR. Plasminogen activator inhibitor-1 contributes to the deleterious effect of obesity on the outcome of thrombotic ischemic stroke in mice. J Thromb Haemost 2007; 5:1726-1731.
-
(2007)
J Thromb Haemost
, vol.5
, pp. 1726-1731
-
-
Nagai, N.1
Van Hoef, B.2
Lijnen, H.R.3
-
31
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
Zhang Y, Proenca R, Maffei M, et al. Positional cloning of the mouse obese gene and its human homologue. Nature 1994; 372:425-432.
-
(1994)
Nature
, vol.372
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
-
32
-
-
0035909997
-
Plasma leptin and the risk of cardiovascular disease in the West of Scotland Coronary Prevention Study (WOSCOPS)
-
Wallace AM, McMahon AD, Packard CJ, et al. Plasma leptin and the risk of cardiovascular disease in the West of Scotland Coronary Prevention Study (WOSCOPS). Circulation 2001; 104:3052-3056.
-
(2001)
Circulation
, vol.104
, pp. 3052-3056
-
-
Wallace, A.M.1
McMahon, A.D.2
Packard, C.J.3
-
33
-
-
7044222808
-
Plasma leptin and prognosis in patients with established coronary atherosclerosis
-
Wolk R, Berger P, Lennon RJ, et al. Plasma leptin and prognosis in patients with established coronary atherosclerosis. J Am Coll Cardiol 2004; 44:1819-1824.
-
(2004)
J Am Coll Cardiol
, vol.44
, pp. 1819-1824
-
-
Wolk, R.1
Berger, P.2
Lennon, R.J.3
-
34
-
-
0037012483
-
Effect of leptin on arterial thrombosis following vascular injury in mice
-
Bodary PF, Westrick RJ, Wickenheiser KJ, et al. Effect of leptin on arterial thrombosis following vascular injury in mice. JAMA 2002; 287:1706-1709.
-
(2002)
JAMA
, vol.287
, pp. 1706-1709
-
-
Bodary, P.F.1
Westrick, R.J.2
Wickenheiser, K.J.3
-
35
-
-
36049041393
-
Leptin signalling and leptin-mediated activation of human platelets: Importance of JAK2 and the phospholipases Cgamma2 and A2
-
Dellas C, Schafer K, Rohm IK, et al. Leptin signalling and leptin-mediated activation of human platelets: importance of JAK2 and the phospholipases Cgamma2 and A2. Thromb Haemost 2007; 98:1063-1071.
-
(2007)
Thromb Haemost
, vol.98
, pp. 1063-1071
-
-
Dellas, C.1
Schafer, K.2
Rohm, I.K.3
-
36
-
-
0032971218
-
Leptin promotes aggregation of human platelets via the long form of its receptor
-
Nakata M, Yada T, Soejima N, Maruyama I. Leptin promotes aggregation of human platelets via the long form of its receptor. Diabetes 1999; 48:426-429.
-
(1999)
Diabetes
, vol.48
, pp. 426-429
-
-
Nakata, M.1
Yada, T.2
Soejima, N.3
Maruyama, I.4
-
37
-
-
0035179087
-
Leptin-dependent platelet aggregation and arterial thrombosis suggests a mechanism for atherothrombotic disease in obesity
-
Konstantinides S, Schafer K, Koschnick S, Loskutoff DJ. Leptin-dependent platelet aggregation and arterial thrombosis suggests a mechanism for atherothrombotic disease in obesity. J Clin Invest 2001; 108:1533-1540.
-
(2001)
J Clin Invest
, vol.108
, pp. 1533-1540
-
-
Konstantinides, S.1
Schafer, K.2
Koschnick, S.3
Loskutoff, D.J.4
-
38
-
-
34548151859
-
Leptin induces C-reactive protein expression in vascular endothelial cells
-
Singh P, Hoffmann M, Wolk R, et al. Leptin induces C-reactive protein expression in vascular endothelial cells. Arterioscler Thromb Vasc Biol 2007; 27:e302-e307.
-
(2007)
Arterioscler Thromb Vasc Biol
, vol.27
-
-
Singh, P.1
Hoffmann, M.2
Wolk, R.3
-
39
-
-
77955981037
-
Epicardial perivascular adiposederived leptin exacerbates coronary endothelial dysfunction in metabolic syndrome via a protein kinase C-beta pathway
-
Payne GA, Borbouse L, Kumar S, et al. Epicardial perivascular adiposederived leptin exacerbates coronary endothelial dysfunction in metabolic syndrome via a protein kinase C-beta pathway. Arterioscler Thromb Vasc Biol 2010; 30:1711-1717.
-
(2010)
Arterioscler Thromb Vasc Biol
, vol.30
, pp. 1711-1717
-
-
Payne, G.A.1
Borbouse, L.2
Kumar, S.3
-
40
-
-
0035905758
-
The hormone resistin links obesity to diabetes
-
Steppan CM, Bailey ST, Bhat S, et al. The hormone resistin links obesity to diabetes. Nature 2001; 409:307-312.
-
(2001)
Nature
, vol.409
, pp. 307-312
-
-
Steppan, C.M.1
Bailey, S.T.2
Bhat, S.3
-
41
-
-
0043164953
-
Resistin promotes endothelial cell activation: Further evidence of adipokine-endothelial interaction
-
Verma S, Li SH, Wang CH, et al. Resistin promotes endothelial cell activation: further evidence of adipokine-endothelial interaction. Circulation 2003; 108:736-740.
-
(2003)
Circulation
, vol.108
, pp. 736-740
-
-
Verma, S.1
Li, S.H.2
Wang, C.H.3
-
42
-
-
19944433652
-
Visfatin: A protein secreted by visceral fat that mimics the effects of insulin
-
Fukuhara A, Matsuda M, Nishizawa M, et al. Visfatin: a protein secreted by visceral fat that mimics the effects of insulin. Science 2005; 307:426-430.
-
(2005)
Science
, vol.307
, pp. 426-430
-
-
Fukuhara, A.1
Matsuda, M.2
Nishizawa, M.3
-
43
-
-
35549002189
-
Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme
-
Revollo JR, Korner A, Mills KF, et al. Nampt/PBEF/Visfatin regulates insulin secretion in beta cells as a systemic NAD biosynthetic enzyme. Cell Metab 2007; 6:363-375.
-
(2007)
Cell Metab
, vol.6
, pp. 363-375
-
-
Revollo, J.R.1
Korner, A.2
Mills, K.F.3
-
44
-
-
41949100421
-
Visfatin enhances ICAM-1 and VCAM-1 expression through ROS-dependent NF-kappaB activation in endothelial cells
-
Kim SR, Bae YH, Bae SK, et al. Visfatin enhances ICAM-1 and VCAM-1 expression through ROS-dependent NF-kappaB activation in endothelial cells. Biochim Biophys Acta 2008; 1783:886-895.
-
(2008)
Biochim Biophys Acta
, vol.1783
, pp. 886-895
-
-
Kim, S.R.1
Bae, Y.H.2
Bae, S.K.3
-
45
-
-
84864269536
-
Visfatin/NAMPT: A multifaceted molecule with diverse roles in physiology and pathophysiology
-
Dahl TB, Holm S, Aukrust P, Halvorsen B. Visfatin/NAMPT: a multifaceted molecule with diverse roles in physiology and pathophysiology. Annu Rev Nutr 2012; 32:229-243.
-
(2012)
Annu Rev Nutr
, vol.32
, pp. 229-243
-
-
Dahl, T.B.1
Holm, S.2
Aukrust, P.3
Halvorsen, B.4
-
46
-
-
84865221064
-
Visfatin/NAMPT: A hot spot in thrombosis?
-
Halvorsen B, Dahl TB, Aukrust P. Visfatin/NAMPT: a hot spot in thrombosis? Thromb Res 2012; 130:289-290.
-
(2012)
Thromb Res
, vol.130
, pp. 289-290
-
-
Halvorsen, B.1
Dahl, T.B.2
Aukrust, P.3
-
47
-
-
33847279330
-
Increased expression of visfatin in macrophages of human unstable carotid and coronary atherosclerosis: Possible role in inflammation and plaque destabilization
-
Dahl TB, Yndestad A, Skjelland M, et al. Increased expression of visfatin in macrophages of human unstable carotid and coronary atherosclerosis: possible role in inflammation and plaque destabilization. Circulation 2007; 115:972-980.
-
(2007)
Circulation
, vol.115
, pp. 972-980
-
-
Dahl, T.B.1
Yndestad, A.2
Skjelland, M.3
-
48
-
-
0033613545
-
Novel modulator for endothelial adhesion molecules: Adipocyte-derived plasma protein adiponectin
-
Ouchi N, Kihara S, Arita Y, et al. Novel modulator for endothelial adhesion molecules: adipocyte-derived plasma protein adiponectin. Circulation 1999; 100:2473-2476.
-
(1999)
Circulation
, vol.100
, pp. 2473-2476
-
-
Ouchi, N.1
Kihara, S.2
Arita, Y.3
-
49
-
-
34249900491
-
Adiponectin deficiency increases leukocyte-endothelium interactions via upregulation of endothelial cell adhesion molecules in vivo
-
Ouedraogo R, Gong Y, Berzins B, et al. Adiponectin deficiency increases leukocyte-endothelium interactions via upregulation of endothelial cell adhesion molecules in vivo. J Clin Invest 2007; 117:1718-1726.
-
(2007)
J Clin Invest
, vol.117
, pp. 1718-1726
-
-
Ouedraogo, R.1
Gong, Y.2
Berzins, B.3
-
50
-
-
0037129861
-
Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell
-
Arita Y, Kihara S, Ouchi N, et al. Adipocyte-derived plasma protein adiponectin acts as a platelet-derived growth factor-BB-binding protein and regulates growth factor-induced common postreceptor signal in vascular smooth muscle cell. Circulation 2002; 105:2893-2898.
-
(2002)
Circulation
, vol.105
, pp. 2893-2898
-
-
Arita, Y.1
Kihara, S.2
Ouchi, N.3
-
51
-
-
2442464884
-
Adiponectin specifically increased tissue inhibitor of metalloproteinase-1 through interleukin-10 expression in human macrophages
-
Kumada M, Kihara S, Ouchi N, et al. Adiponectin specifically increased tissue inhibitor of metalloproteinase-1 through interleukin-10 expression in human macrophages. Circulation 2004; 109:2046-2049.
-
(2004)
Circulation
, vol.109
, pp. 2046-2049
-
-
Kumada, M.1
Kihara, S.2
Ouchi, N.3
-
52
-
-
48949094221
-
Adiponectin inhibits tissue factor expression and enhances tissue factor pathway inhibitor expression in human endothelial cells
-
Chen YJ, Zhang LQ, Wang GP, et al. Adiponectin inhibits tissue factor expression and enhances tissue factor pathway inhibitor expression in human endothelial cells. Thromb Haemost 2008; 100:291-300.
-
(2008)
Thromb Haemost
, vol.100
, pp. 291-300
-
-
Chen, Y.J.1
Zhang, L.Q.2
Wang, G.P.3
-
53
-
-
84872420425
-
Adiponectin inhibits macrophage tissue factor, a key trigger of thrombosis in disrupted atherosclerotic plaques
-
Okamoto Y, Ishii S, Croce K, et al. Adiponectin inhibits macrophage tissue factor, a key trigger of thrombosis in disrupted atherosclerotic plaques. Atherosclerosis 2013; 226:373-377.
-
(2013)
Atherosclerosis
, vol.226
, pp. 373-377
-
-
Okamoto, Y.1
Ishii, S.2
Croce, K.3
-
54
-
-
20144380036
-
Apelin, a newly identified adipokine up-regulated by insulin and obesity
-
Boucher J, Masri B, Daviaud D, et al. Apelin, a newly identified adipokine up-regulated by insulin and obesity. Endocrinology 2005; 146:1764-1771.
-
(2005)
Endocrinology
, vol.146
, pp. 1764-1771
-
-
Boucher, J.1
Masri, B.2
Daviaud, D.3
-
55
-
-
79959630420
-
Apelin, diabetes, and obesity
-
Castan-Laurell I, Dray C, Attane C, et al. Apelin, diabetes, and obesity. Endocrine 2011; 40:1-9.
-
(2011)
Endocrine
, vol.40
, pp. 1-9
-
-
Castan-Laurell, I.1
Dray, C.2
Attane, C.3
-
56
-
-
70350462121
-
Endogenous regulation of cardiovascular function by apelin-APJ
-
Charo DN, Ho M, Fajardo G, et al. Endogenous regulation of cardiovascular function by apelin-APJ. Am J Physiol Heart Circ Physiol 2009; 297:H1904-H1913.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
-
-
Charo, D.N.1
Ho, M.2
Fajardo, G.3
-
57
-
-
55849094397
-
Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis
-
Chun HJ, Ali ZA, Kojima Y, et al. Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis. J Clin Invest 2008; 118:3343-3354.
-
(2008)
J Clin Invest
, vol.118
, pp. 3343-3354
-
-
Chun, H.J.1
Ali, Z.A.2
Kojima, Y.3
-
58
-
-
84871887199
-
Apelin/APJ signaling is a critical regulator of statin effects in vascular endothelial cells: Brief report
-
McLean DL, Kim J, Kang Y, et al. Apelin/APJ signaling is a critical regulator of statin effects in vascular endothelial cells: brief report. Arterioscler Thromb Vasc Biol 2012; 32:2640-2643.
-
(2012)
Arterioscler Thromb Vasc Biol
, vol.32
, pp. 2640-2643
-
-
McLean, D.L.1
Kim, J.2
Kang, Y.3
-
59
-
-
79952745361
-
Apelin protects against angiotensin II-induced cardiovascular fibrosis and decreases plasminogen activator inhibitor type-1 production
-
Siddiquee K, Hampton J, Khan S, et al. Apelin protects against angiotensin II-induced cardiovascular fibrosis and decreases plasminogen activator inhibitor type-1 production. J Hypertens 2011; 29:724-731.
-
(2011)
J Hypertens
, vol.29
, pp. 724-731
-
-
Siddiquee, K.1
Hampton, J.2
Khan, S.3
-
60
-
-
84865146998
-
APJ acts as a dual receptor in cardiac hypertrophy
-
Scimia MC, Hurtado C, Ray S, et al. APJ acts as a dual receptor in cardiac hypertrophy. Nature 2012; 488:394-398.
-
(2012)
Nature
, vol.488
, pp. 394-398
-
-
Scimia, M.C.1
Hurtado, C.2
Ray, S.3
-
61
-
-
82755189644
-
MicroRNA history: Discovery, recent applications, and next frontiers
-
Almeida MI, Reis RM, Calin GA. MicroRNA history: discovery, recent applications, and next frontiers. Mutat Res 2011; 717:1-8.
-
(2011)
Mutat Res
, vol.717
, pp. 1-8
-
-
Almeida, M.I.1
Reis, R.M.2
Calin, G.A.3
-
62
-
-
77955644289
-
Mammalian microRNAs predominantly act to decrease target mRNA levels
-
Guo H, Ingolia NT, Weissman JS, Bartel DP. Mammalian microRNAs predominantly act to decrease target mRNA levels. Nature 2010; 466: 835-840.
-
(2010)
Nature
, vol.466
, pp. 835-840
-
-
Guo, H.1
Ingolia, N.T.2
Weissman, J.S.3
Bartel, D.P.4
-
63
-
-
84873817376
-
MicroRNAs in cardiovascular disease: From pathogenesis to prevention and treatment
-
Quiat D, Olson EN. MicroRNAs in cardiovascular disease: from pathogenesis to prevention and treatment. J Clin Invest 2013; 123:11-18.
-
(2013)
J Clin Invest
, vol.123
, pp. 11-18
-
-
Quiat, D.1
Olson, E.N.2
-
64
-
-
77957259803
-
Plasma microRNA profiling reveals loss of endothelial miR-126 and other microRNAs in type 2 diabetes
-
Zampetaki A, Kiechl S, Drozdov I, et al. Plasma microRNA profiling reveals loss of endothelial miR-126 and other microRNAs in type 2 diabetes. Circ Res 2010; 107:810-817.
-
(2010)
Circ Res
, vol.107
, pp. 810-817
-
-
Zampetaki, A.1
Kiechl, S.2
Drozdov, I.3
-
65
-
-
84857932052
-
Role of microRNAs in diabetes and its cardiovascular complications
-
Shantikumar S, Caporali A, Emanueli C. Role of microRNAs in diabetes and its cardiovascular complications. Cardiovasc Res 2012; 93:583-593.
-
(2012)
Cardiovasc Res
, vol.93
, pp. 583-593
-
-
Shantikumar, S.1
Caporali, A.2
Emanueli, C.3
-
66
-
-
84874715061
-
Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b
-
Kornfeld JW, Baitzel C, Konner AC, et al. Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b. Nature 2013; 494:111-115.
-
(2013)
Nature
, vol.494
, pp. 111-115
-
-
Kornfeld, J.W.1
Baitzel, C.2
Konner, A.C.3
-
67
-
-
80054971110
-
Inhibition of miR-33a/b in nonhuman primates raises plasma HDL and lowers VLDL triglycerides
-
Rayner KJ, Esau CC, Hussain FN, et al. Inhibition of miR-33a/b in nonhuman primates raises plasma HDL and lowers VLDL triglycerides. Nature 2011; 478:404-407.
-
(2011)
Nature
, vol.478
, pp. 404-407
-
-
Rayner, K.J.1
Esau, C.C.2
Hussain, F.N.3
-
68
-
-
84865859807
-
MiR-421 and miR-30c inhibit SERPINE 1 gene expression in human endothelial cells
-
Marchand A, Proust C, Morange PE, et al. miR-421 and miR-30c inhibit SERPINE 1 gene expression in human endothelial cells. PLoS One 2012; 7:e44532.
-
(2012)
PLoS One
, vol.7
-
-
Marchand, A.1
Proust, C.2
Morange, P.E.3
-
69
-
-
40349103409
-
MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1
-
Harris TA, Yamakuchi M, Ferlito M, et al. MicroRNA-126 regulates endothelial expression of vascular cell adhesion molecule 1. Proc Natl Acad Sci U S A 2008; 105:1516-1521.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 1516-1521
-
-
Harris, T.A.1
Yamakuchi, M.2
Ferlito, M.3
-
70
-
-
77954758345
-
Short communication: Asymmetric dimethylarginine impairs angiogenic progenitor cell function in patients with coronary artery disease through a microRNA-21-dependent mechanism
-
Fleissner F, Jazbutyte V, Fiedler J, et al. Short communication: asymmetric dimethylarginine impairs angiogenic progenitor cell function in patients with coronary artery disease through a microRNA-21-dependent mechanism. Circ Res 2010; 107:138-143.
-
(2010)
Circ Res
, vol.107
, pp. 138-143
-
-
Fleissner, F.1
Jazbutyte, V.2
Fiedler, J.3
-
71
-
-
84872183938
-
The complex transcriptional landscape of the anucleate human platelet
-
Bray PF, McKenzie SE, Edelstein LC, et al. The complex transcriptional landscape of the anucleate human platelet. BMC Genomics 2013; 14:1.
-
(2013)
BMC Genomics
, vol.14
, pp. 1
-
-
Bray, P.F.1
McKenzie, S.E.2
Edelstein, L.C.3
-
72
-
-
69949124465
-
Existence of a microRNA pathway in anucleate platelets
-
Landry P, Plante I, Ouellet DL, et al. Existence of a microRNA pathway in anucleate platelets. Nat Struct Mol Biol 2009; 16:961-966.
-
(2009)
Nat Struct Mol Biol
, vol.16
, pp. 961-966
-
-
Landry, P.1
Plante, I.2
Ouellet, D.L.3
-
73
-
-
79955948510
-
Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity
-
Nagalla S, Shaw C, Kong X, et al. Platelet microRNA-mRNA coexpression profiles correlate with platelet reactivity. Blood 2011; 117:5189-5197.
-
(2011)
Blood
, vol.117
, pp. 5189-5197
-
-
Nagalla, S.1
Shaw, C.2
Kong, X.3
-
74
-
-
84874230935
-
Circulating microRNAs as novel biomarkers for platelet activation
-
Willeit P, Zampetaki A, Dudek K, et al. Circulating microRNAs as novel biomarkers for platelet activation. Circ Res 2013; 112:595-600.
-
(2013)
Circ Res
, vol.112
, pp. 595-600
-
-
Willeit, P.1
Zampetaki, A.2
Dudek, K.3
-
75
-
-
74749096058
-
VAMP8/endobrevin is overexpressed in hyperreactive human platelets: Suggested role for platelet microRNA
-
Kondkar AA, Bray MS, Leal SM, et al. VAMP8/endobrevin is overexpressed in hyperreactive human platelets: suggested role for platelet microRNA. J Thromb Haemost 2010; 8:369-378.
-
(2010)
J Thromb Haemost
, vol.8
, pp. 369-378
-
-
Kondkar, A.A.1
Bray, M.S.2
Leal, S.M.3
-
76
-
-
84879213663
-
Comparison of initial warfarin response in obese patients versus nonobese patients
-
[Epub ahead of print]
-
Wallace JL, Reaves AB, Tolley EA, et al. Comparison of initial warfarin response in obese patients versus nonobese patients. J Thromb Thrombolysis 2012. [Epub ahead of print]
-
(2012)
J Thromb Thrombolysis
-
-
Wallace, J.L.1
Reaves, A.B.2
Tolley, E.A.3
-
77
-
-
0038630900
-
Enoxaparin effect depends on body-weight and current doses may be inadequate in obese patients
-
Frederiksen SG, Hedenbro JL, Norgren L. Enoxaparin effect depends on body-weight and current doses may be inadequate in obese patients. Br J Surg 2003; 90:547-548.
-
(2003)
Br J Surg
, vol.90
, pp. 547-548
-
-
Frederiksen, S.G.1
Hedenbro, J.L.2
Norgren, L.3
-
78
-
-
84856804647
-
Parenteral anticoagulants: Antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
-
Garcia DA, Baglin TP, Weitz JI, et al. Parenteral anticoagulants: Antithrombotic therapy and prevention of thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012; 141:e24S-e43S.
-
(2012)
Chest
, vol.141
-
-
Garcia, D.A.1
Baglin, T.P.2
Weitz, J.I.3
-
79
-
-
0029556412
-
The effect of sodium salicylate and aspirin on NF-kappa B
-
Frantz B, O'Neill EA. The effect of sodium salicylate and aspirin on NF-kappa B. Science 1995; 270:2017-2019.
-
(1995)
Science
, vol.270
, pp. 2017-2019
-
-
Frantz, B.1
O'neill, E.A.2
-
81
-
-
56749106312
-
Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein
-
Ridker PM, Danielson E, Fonseca FA, et al. Rosuvastatin to prevent vascular events in men and women with elevated C-reactive protein. N Engl J Med 2008; 359:2195-2207.
-
(2008)
N Engl J Med
, vol.359
, pp. 2195-2207
-
-
Ridker, P.M.1
Danielson, E.2
Fonseca, F.A.3
-
82
-
-
79151478555
-
Type 2 diabetes as an inflammatory disease
-
Donath MY, Shoelson SE. Type 2 diabetes as an inflammatory disease. Nat Rev Immunol 2011; 11:98-107.
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 98-107
-
-
Donath, M.Y.1
Shoelson, S.E.2
-
83
-
-
79955604190
-
Anti-inflammatory therapeutics for the treatment of atherosclerosis
-
Charo IF, Taub R. Anti-inflammatory therapeutics for the treatment of atherosclerosis. Nat Rev Drug Discov 2011; 10:365-376.
-
(2011)
Nat Rev Drug Discov
, vol.10
, pp. 365-376
-
-
Charo, I.F.1
Taub, R.2
-
84
-
-
84872328960
-
Characterization of a small molecule inhibitor of plasminogen activator inhibitor type 1 that accelerates the transition into the latent conformation
-
Fjellstrom O, Deinum J, Sjogren T, et al. Characterization of a small molecule inhibitor of plasminogen activator inhibitor type 1 that accelerates the transition into the latent conformation. J Biol Chem 2013; 288:873-885.
-
(2013)
J Biol Chem
, vol.288
, pp. 873-885
-
-
Fjellstrom, O.1
Deinum, J.2
Sjogren, T.3
-
85
-
-
84879333770
-
Plasminogen activator inhibitor-1 inhibitors: A patent review (2006 - Present)
-
[Epub ahead of print]
-
Fortenberry YM. Plasminogen activator inhibitor-1 inhibitors: a patent review (2006 - present). Expert Opin Ther Pat 2013. [Epub ahead of print]
-
(2013)
Expert Opin Ther Pat
-
-
Fortenberry, Y.M.1
-
86
-
-
84855405202
-
A second chance for a PPARgamma targeted therapy?
-
Norris AW, Sigmund CD. A second chance for a PPARgamma targeted therapy? Circ Res 2012; 110:8-11.
-
(2012)
Circ Res
, vol.110
, pp. 8-11
-
-
Norris, A.W.1
Sigmund, C.D.2
-
87
-
-
28444438100
-
Pioglitazone protects against thrombosis in a mouse model of obesity and insulin resistance
-
Bodary PF, Vargas FB, King SA, et al. Pioglitazone protects against thrombosis in a mouse model of obesity and insulin resistance. J Thromb Haemost 2005; 3:2149-2153.
-
(2005)
J Thromb Haemost
, vol.3
, pp. 2149-2153
-
-
Bodary, P.F.1
Vargas, F.B.2
King, S.A.3
-
88
-
-
84874430535
-
Role of adipokines in cardiovascular disease
-
Mattu HS, Randeva HS. Role of adipokines in cardiovascular disease. J Endocrinol 2013; 216:T17-T36.
-
(2013)
J Endocrinol
, vol.216
-
-
Mattu, H.S.1
Randeva, H.S.2
-
89
-
-
84866054749
-
Therapeutic use of recombinant methionyl human leptin
-
Vatier C, Gautier JF, Vigouroux C. Therapeutic use of recombinant methionyl human leptin. Biochimie 2012; 94:2116-2125.
-
(2012)
Biochimie
, vol.94
, pp. 2116-2125
-
-
Vatier, C.1
Gautier, J.F.2
Vigouroux, C.3
-
90
-
-
84866076374
-
Leptin revisited: Its mechanism of action and potential for treating diabetes
-
Coppari R, Bjorbaek C. Leptin revisited: its mechanism of action and potential for treating diabetes. Nat Rev Drug Discov 2012; 11:692-708.
-
(2012)
Nat Rev Drug Discov
, vol.11
, pp. 692-708
-
-
Coppari, R.1
Bjorbaek, C.2
-
91
-
-
77954222146
-
Translational promise of the apelin:APJ system
-
Barnes G, Japp AG, Newby DE. Translational promise of the apelin:APJ system. Heart 2010; 96:1011-1016.
-
(2010)
Heart
, vol.96
, pp. 1011-1016
-
-
Barnes, G.1
Japp, A.G.2
Newby, D.E.3
-
92
-
-
84866714190
-
Cardiovascular effects of a PEGylated apelin
-
Jia ZQ, Hou L, Leger A, et al. Cardiovascular effects of a PEGylated apelin. Peptides 2012; 38:181-188.
-
(2012)
Peptides
, vol.38
, pp. 181-188
-
-
Jia, Z.Q.1
Hou, L.2
Leger, A.3
-
93
-
-
79960018147
-
Adiponectin is required for PPARgammamediated improvement of endothelial function in diabetic mice
-
Wong WT, Tian XY, Xu A, et al. Adiponectin is required for PPARgammamediated improvement of endothelial function in diabetic mice. Cell Metab 2011; 14:104-115.
-
(2011)
Cell Metab
, vol.14
, pp. 104-115
-
-
Wong, W.T.1
Tian, X.Y.2
Xu, A.3
-
94
-
-
50949099615
-
Hypoxia-induced apelin expression regulates endothelial cell proliferation and regenerative angiogenesis
-
Eyries M, Siegfried G, Ciumas M, et al. Hypoxia-induced apelin expression regulates endothelial cell proliferation and regenerative angiogenesis. Circ Res 2008; 103:432-440.
-
(2008)
Circ Res
, vol.103
, pp. 432-440
-
-
Eyries, M.1
Siegfried, G.2
Ciumas, M.3
-
95
-
-
77951078472
-
Apelin induces enlarged and nonleaky blood vessels for functional recovery from ischemia
-
Kidoya H, Naito H, Takakura N. Apelin induces enlarged and nonleaky blood vessels for functional recovery from ischemia. Blood 2010; 115:3166-3174.
-
(2010)
Blood
, vol.115
, pp. 3166-3174
-
-
Kidoya, H.1
Naito, H.2
Takakura, N.3
-
97
-
-
84865682650
-
Single-stranded siRNAs activate RNAi in animals
-
Lima WF, Prakash TP, Murray HM, et al. Single-stranded siRNAs activate RNAi in animals. Cell 2012; 150:883-894.
-
(2012)
Cell
, vol.150
, pp. 883-894
-
-
Lima, W.F.1
Prakash, T.P.2
Murray, H.M.3
|