-
1
-
-
0347444723
-
MicroRNAs: Genomics, biogenesis, mechanism, and function
-
Bartel, D.P. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell, 2004, 116, 281-297.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
2
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
Bartel, D.P. MicroRNAs: target recognition and regulatory functions. Cell, 2009, 136, 215-233.
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
3
-
-
84858446579
-
MicroRNAs and their targets: Recognition, regulation and an emerging reciprocal relationship
-
Pasquinelli, A.E. MicroRNAs and their targets: recognition, regulation and an emerging reciprocal relationship. Nat. Rev. Genet., 2012, 13, 271-282.
-
(2012)
Nat. Rev. Genet
, vol.13
, pp. 271-282
-
-
Pasquinelli, A.E.1
-
4
-
-
0035966319
-
MicroRNAs: Tiny regulators with great potential
-
Ambros, V. microRNAs: tiny regulators with great potential. Cell, 2001, 107, 823-826.
-
(2001)
Cell
, vol.107
, pp. 823-826
-
-
Ambros, V.1
-
5
-
-
3042767202
-
MicroRNAs: Small RNAs with a big role in gene regulation
-
He, L.; Hannon, G.J. MicroRNAs: small RNAs with a big role in gene regulation. Nat. Rev. Genet., 2004, 5, 522-531.
-
(2004)
Nat. Rev. Genet
, vol.5
, pp. 522-531
-
-
He, L.1
Hannon, G.J.2
-
6
-
-
0038299558
-
Role of microRNAs in plant and animal development
-
Carrington, J.C.; Ambros, V. Role of microRNAs in plant and animal development. Science, 2003, 301, 336-338.
-
(2003)
Science
, vol.301
, pp. 336-338
-
-
Carrington, J.C.1
Ambros, V.2
-
7
-
-
22844440427
-
Identification of hundreds of conserved and nonconserved human microRNAs
-
Bentwich, I.; Avniel, A.; Karov, Y.; Aharonov, R.; Gilad, S.; Barad, O.; Barzilai, A.; Einat, P.; Einav, U.; Meiri, E.; Sharon, E.; Spector, Y.; Bentwich, Z. Identification of hundreds of conserved and nonconserved human microRNAs. Nat. Genet., 2005, 37, 766-770.
-
(2005)
Nat. Genet
, vol.37
, pp. 766-770
-
-
Bentwich, I.1
Avniel, A.2
Karov, Y.3
Aharonov, R.4
Gilad, S.5
Barad, O.6
Barzilai, A.7
Einat, P.8
Einav, U.9
Meiri, E.10
Sharon, E.11
Spector, Y.12
Bentwich, Z.13
-
8
-
-
11844278458
-
Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets
-
Lewis, B.P.; Burge, C.B.; Bartel, D.P. Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets. Cell, 2005, 120, 15-20.
-
(2005)
Cell
, vol.120
, pp. 15-20
-
-
Lewis, B.P.1
Burge, C.B.2
Bartel, D.P.3
-
9
-
-
60149095444
-
Most mammalian mRNAs are conserved targets of microRNAs
-
Friedman, R.C.; Farh, K.K.; Burge, C.B.; Bartel, D.P. Most mammalian mRNAs are conserved targets of microRNAs. Genome Res., 2009, 19, 92-105.
-
(2009)
Genome Res
, vol.19
, pp. 92-105
-
-
Friedman, R.C.1
Farh, K.K.2
Burge, C.B.3
Bartel, D.P.4
-
10
-
-
84860324470
-
Roles for microRNAs in conferring robustness to biological processes
-
Ebert, M.S.; Sharp, P.A. Roles for microRNAs in conferring robustness to biological processes. Cell, 2012, 149, 515-524.
-
(2012)
Cell
, vol.149
, pp. 515-524
-
-
Ebert, M.S.1
Sharp, P.A.2
-
11
-
-
84858776574
-
MicroRNAs in metabolism and metabolic disorders
-
Rottiers, V.; Naar, A.M. MicroRNAs in metabolism and metabolic disorders. Nat. Rev. Mol. Cell Biol., 2012, 13, 239-250.
-
(2012)
Nat. Rev. Mol. Cell Biol
, vol.13
, pp. 239-250
-
-
Rottiers, V.1
Naar, A.M.2
-
12
-
-
78751660177
-
Pervasive roles of microRNAs in cardiovascular biology
-
Small, E.M.; Olson, E.N. Pervasive roles of microRNAs in cardiovascular biology. Nature, 2011, 469, 336-342.
-
(2011)
Nature
, vol.469
, pp. 336-342
-
-
Small, E.M.1
Olson, E.N.2
-
13
-
-
84857079737
-
The microcosmos of cancer
-
Lujambio, A.; Lowe, S.W. The microcosmos of cancer. Nature, 2012, 482, 347-355.
-
(2012)
Nature
, vol.482
, pp. 347-355
-
-
Lujambio, A.1
Lowe, S.W.2
-
14
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
Lu, J.; Getz, G.; Miska, E.A.; Alvarez-Saavedra, E.; Lamb, J.; Peck, D.; Sweet-Cordero, A.; Ebert, B.L.; Mak, R.H.; Ferrando, A.A.; Downing, J.R.; Jacks, T.; Horvitz, H.R.; Golub, T.R. MicroRNA expression profiles classify human cancers. Nature, 2005, 435, 834-838.
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
Alvarez-Saavedra, E.4
Lamb, J.5
Peck, D.6
Sweet-Cordero, A.7
Ebert, B.L.8
Mak, R.H.9
Ferrando, A.A.10
Downing, J.R.11
Jacks, T.12
Horvitz, H.R.13
Golub, T.R.14
-
15
-
-
33846188098
-
MicroRNAs as oncogenes and tumor suppressors
-
Zhang, B.; Pan, X.; Cobb, G.P.; Anderson, T.A. microRNAs as oncogenes and tumor suppressors. Dev. Biol., 2007, 302, 1-12.
-
(2007)
Dev. Biol
, vol.302
, pp. 1-12
-
-
Zhang, B.1
Pan, X.2
Cobb, G.P.3
Anderson, T.A.4
-
16
-
-
77449141681
-
Small molecule modifiers of the microRNA and RNA interference pathway
-
Deiters, A. Small molecule modifiers of the microRNA and RNA interference pathway. AAPS J., 2010, 12, 51-60.
-
(2010)
AAPS J
, vol.12
, pp. 51-60
-
-
Deiters, A.1
-
17
-
-
78649972032
-
Serum microRNA profiles serve as novel biomarkers for HBV infection and diagnosis of HBVpositive hepatocarcinoma
-
Li, L.M.; Hu, Z.B.; Zhou, Z.X.; Chen, X.; Liu, F.Y.; Zhang, J.F.; Shen, H.B.; Zhang, C.Y.; Zen, K. Serum microRNA profiles serve as novel biomarkers for HBV infection and diagnosis of HBVpositive hepatocarcinoma. Cancer Res., 2010, 70, 9798-9807.
-
(2010)
Cancer Res
, vol.70
, pp. 9798-9807
-
-
Li, L.M.1
Hu, Z.B.2
Zhou, Z.X.3
Chen, X.4
Liu, F.Y.5
Zhang, J.F.6
Shen, H.B.7
Zhang, C.Y.8
Zen, K.9
-
18
-
-
84856358368
-
Identification of ten serum microRNAs from a genome-wide serum microRNA expression profile as novel noninvasive biomarkers for nonsmall cell lung cancer diagnosis
-
Chen, X.; Hu, Z.; Wang, W.; Ba, Y.; Ma, L.; Zhang, C.; Wang, C.; Ren, Z.; Zhao, Y.; Wu, S.; Zhuang, R.; Zhang, Y.; Hu, H.; Liu, C.; Xu, L.; Wang, J.; Shen, H.; Zhang, J.; Zen, K.; Zhang, C.Y. Identification of ten serum microRNAs from a genome-wide serum microRNA expression profile as novel noninvasive biomarkers for nonsmall cell lung cancer diagnosis. Int. J. Cancer., 2012, 130, 1620-1628.
-
(2012)
Int. J. Cancer
, vol.130
, pp. 1620-1628
-
-
Chen, X.1
Hu, Z.2
Wang, W.3
Ba, Y.4
Ma, L.5
Zhang, C.6
Wang, C.7
Ren, Z.8
Zhao, Y.9
Wu, S.10
Zhuang, R.11
Zhang, Y.12
Hu, H.13
Liu, C.14
Xu, L.15
Wang, J.16
Shen, H.17
Zhang, J.18
Zen, K.19
Zhang, C.Y.20
more..
-
19
-
-
78649887520
-
Expression profile of microRNAs in serum: A fingerprint for esophageal squamous cell carcinoma
-
Zhang, C.; Wang, C.; Chen, X.; Yang, C.; Li, K.; Wang, J.; Dai, J.; Hu, Z.; Zhou, X.; Chen, L.; Zhang, Y.; Li, Y.; Qiu, H.; Xing, J.; Liang, Z.; Ren, B.; Yang, C.; Zen, K.; Zhang, C.Y. Expression profile of microRNAs in serum: a fingerprint for esophageal squamous cell carcinoma. Clin. Chem., 2010, 56, 1871-1879.
-
(2010)
Clin. Chem
, vol.56
, pp. 1871-1879
-
-
Zhang, C.1
Wang, C.2
Chen, X.3
Yang, C.4
Li, K.5
Wang, J.6
Dai, J.7
Hu, Z.8
Zhou, X.9
Chen, L.10
Zhang, Y.11
Li, Y.12
Qiu, H.13
Xing, J.14
Liang, Z.15
Ren, B.16
Yang, C.17
Zen, K.18
Zhang, C.Y.19
-
20
-
-
84863259319
-
Circulating microRNAs: A novel class of biomarkers to diagnose and monitor human cancers
-
Zen, K.; Zhang, C.Y. Circulating microRNAs: a novel class of biomarkers to diagnose and monitor human cancers. Med. Res. Rev., 2012, 32, 326-348.
-
(2012)
Med. Res. Rev
, vol.32
, pp. 326-348
-
-
Zen, K.1
Zhang, C.Y.2
-
21
-
-
45849149251
-
Cancerous miRNAs and their regulation
-
Shi, X.B.; Tepper, C.G.; deVere White, R.W. Cancerous miRNAs and their regulation. Cell Cycle, 2008, 7, 1529-1538.
-
(2008)
Cell Cycle
, vol.7
, pp. 1529-1538
-
-
Shi, X.B.1
Tepper, C.G.2
Devere White, R.W.3
-
22
-
-
84866423871
-
MicroRNAs in the p53 network: Micromanagement of tumour suppression
-
Hermeking, H. MicroRNAs in the p53 network: micromanagement of tumour suppression. Nat. Rev. Cancer., 2012, 12, 613-626.
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 613-626
-
-
Hermeking, H.1
-
23
-
-
64349101658
-
MicroRNA-125b is a novel negative regulator of p53
-
Le, M.T.; Teh, C.; Shyh-Chang, N.; Xie, H.; Zhou, B.; Korzh, V.; Lodish, H.F.; Lim, B. MicroRNA-125b is a novel negative regulator of p53. Genes Dev., 2009, 23, 862-876.
-
(2009)
Genes Dev
, vol.23
, pp. 862-876
-
-
Le, M.T.1
Teh, C.2
Shyh-Chang, N.3
Xie, H.4
Zhou, B.5
Korzh, V.6
Lodish, H.F.7
Lim, B.8
-
24
-
-
79951812882
-
Negative regulation of the tumor suppressor p53 gene by microRNAs
-
Kumar, M.; Lu, Z.; Takwi, A.A.; Chen, W.; Callander, N.S.; Ramos, K.S.; Young, K.H.; Li, Y. Negative regulation of the tumor suppressor p53 gene by microRNAs. Oncogene, 2011, 30, 843-853.
-
(2011)
Oncogene
, vol.30
, pp. 843-853
-
-
Kumar, M.1
Lu, Z.2
Takwi, A.A.3
Chen, W.4
Callander, N.S.5
Ramos, K.S.6
Young, K.H.7
Li, Y.8
-
25
-
-
27644465844
-
RNAi the natural way
-
Cullen, B.R. RNAi the natural way. Nat. Genet., 2005, 37, 1163-1165.
-
(2005)
Nat. Genet
, vol.37
, pp. 1163-1165
-
-
Cullen, B.R.1
-
26
-
-
8144225486
-
MicroRNA genes are transcribed by RNA polymerase II
-
Lee, Y.; Kim, M.; Han, J.; Yeom, K.H.; Lee, S.; Baek, S.H.; Kim, V.N. MicroRNA genes are transcribed by RNA polymerase II. EMBO J., 2004, 23, 4051-4060.
-
(2004)
EMBO J
, vol.23
, pp. 4051-4060
-
-
Lee, Y.1
Kim, M.2
Han, J.3
Yeom, K.H.4
Lee, S.5
Baek, S.H.6
Kim, V.N.7
-
27
-
-
0141843656
-
The nuclear RNase III Drosha initiates microRNA processing
-
Lee, Y.; Ahn, C.; Han, J.; Choi, H.; Kim, J.; Yim, J.; Lee, J.; Provost, P.; Radmark, O.; Kim, S.; Kim, V.N. The nuclear RNase III Drosha initiates microRNA processing. Nature, 2003, 425, 415-419.
-
(2003)
Nature
, vol.425
, pp. 415-419
-
-
Lee, Y.1
Ahn, C.2
Han, J.3
Choi, H.4
Kim, J.5
Yim, J.6
Lee, J.7
Provost, P.8
Radmark, O.9
Kim, S.10
Kim, V.N.11
-
28
-
-
0347988235
-
Nuclear export of microRNA precursors
-
Lund, E.; Guttinger, S.; Calado, A.; Dahlberg, J.E.; Kutay, U. Nuclear export of microRNA precursors. Science, 2004, 303, 95-98.
-
(2004)
Science
, vol.303
, pp. 95-98
-
-
Lund, E.1
Guttinger, S.2
Calado, A.3
Dahlberg, J.E.4
Kutay, U.5
-
29
-
-
61849137222
-
Many roads to maturity: MicroRNA biogenesis pathways and their regulation
-
Winter, J.; Jung, S.; Keller, S.; Gregory, R.I.; Diederichs, S. Many roads to maturity: microRNA biogenesis pathways and their regulation. Nat. Cell Biol., 2009, 11, 228-234.
-
(2009)
Nat. Cell Biol
, vol.11
, pp. 228-234
-
-
Winter, J.1
Jung, S.2
Keller, S.3
Gregory, R.I.4
Diederichs, S.5
-
30
-
-
58849112575
-
Biogenesis of small RNAs in animals
-
Kim, V.N.; Han, J.; Siomi, M.C. Biogenesis of small RNAs in animals. Nat. Rev. Mol. Cell Biol., 2009, 10, 126-139.
-
(2009)
Nat. Rev. Mol. Cell Biol
, vol.10
, pp. 126-139
-
-
Kim, V.N.1
Han, J.2
Siomi, M.C.3
-
31
-
-
22144489833
-
RNAi: The nuts and bolts of the RISC machine
-
Filipowicz, W. RNAi: the nuts and bolts of the RISC machine. Cell, 2005, 122, 17-20.
-
(2005)
Cell
, vol.122
, pp. 17-20
-
-
Filipowicz, W.1
-
32
-
-
4444368187
-
Argonaute2 is the catalytic engine of mammalian RNAi
-
Liu, J.; Carmell, M.A.; Rivas, F.V.; Marsden, C.G.; Thomson, J.M.; Song, J.J.; Hammond, S.M.; Joshua-Tor, L.; Hannon, G.J. Argonaute2 is the catalytic engine of mammalian RNAi. Science, 2004, 305, 1437-1441.
-
(2004)
Science
, vol.305
, pp. 1437-1441
-
-
Liu, J.1
Carmell, M.A.2
Rivas, F.V.3
Marsden, C.G.4
Thomson, J.M.5
Song, J.J.6
Hammond, S.M.7
Joshua-Tor, L.8
Hannon, G.J.9
-
33
-
-
84862185932
-
The therapeutic potential of microRNAs in cancer
-
Thorsen, S.B.; Obad, S.; Jensen, N.F.; Stenvang, J.; Kauppinen, S. The therapeutic potential of microRNAs in cancer. Cancer J., 2012, 18, 275-284.
-
(2012)
Cancer J
, vol.18
, pp. 275-284
-
-
Thorsen, S.B.1
Obad, S.2
Jensen, N.F.3
Stenvang, J.4
Kauppinen, S.5
-
34
-
-
84859455969
-
High-throughput luciferase reporter assay for small-molecule inhibitors of microRNA function
-
Connelly, C.M.; Thomas, M.; Deiters, A. High-throughput luciferase reporter assay for small-molecule inhibitors of microRNA function. J. Biomol. Screen., 2012, 17, 822-828.
-
(2012)
J. Biomol. Screen
, vol.17
, pp. 822-828
-
-
Connelly, C.M.1
Thomas, M.2
Deiters, A.3
-
35
-
-
84862183043
-
A universal activator of microRNAs identified from photoreaction products
-
Chen, X.J.; Huang, C.M.; Zhang, W.J.; Wu, Y.H.; Chen, X.; Zhang, C.Y.; Zhang, Y. A universal activator of microRNAs identified from photoreaction products. Chem. Commun., 2012, 48, 6432-6434.
-
(2012)
Chem. Commun
, vol.48
, pp. 6432-6434
-
-
Chen, X.J.1
Huang, C.M.2
Zhang, W.J.3
Wu, Y.H.4
Chen, X.5
Zhang, C.Y.6
Zhang, Y.7
-
36
-
-
77953312157
-
Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma
-
Young, D.D.; Connelly, C.M.; Grohmann, C.; Deiters, A. Small molecule modifiers of microRNA miR-122 function for the treatment of hepatitis C virus infection and hepatocellular carcinoma. J. Am. Chem. Soc., 2010, 132, 7976-7981.
-
(2010)
J. Am. Chem. Soc
, vol.132
, pp. 7976-7981
-
-
Young, D.D.1
Connelly, C.M.2
Grohmann, C.3
Deiters, A.4
-
37
-
-
49449096792
-
A small molecule enhances RNA interference and promotes microRNA processing
-
Shan, G.; Li, Y.; Zhang, J.; Li, W.; Szulwach, K.E.; Duan, R.; Faghihi, M.A.; Khalil, A.M.; Lu, L.; Paroo, Z.; Chan, A.W.; Shi, Z.; Liu, Q.; Wahlestedt, C.; He, C.; Jin, P. A small molecule enhances RNA interference and promotes microRNA processing. Nat. Biotechnol., 2008, 26, 933-940.
-
(2008)
Nat. Biotechnol
, vol.26
, pp. 933-940
-
-
Shan, G.1
Li, Y.2
Zhang, J.3
Li, W.4
Szulwach, K.E.5
Duan, R.6
Faghihi, M.A.7
Khalil, A.M.8
Lu, L.9
Paroo, Z.10
Chan, A.W.11
Shi, Z.12
Liu, Q.13
Wahlestedt, C.14
He, C.15
Jin, P.16
-
38
-
-
54749089002
-
Small-molecule inhibitors of microrna miR-21 function
-
Gumireddy, K.; Young, D.D.; Xiong, X.; Hogenesch, J.B.; Huang, Q.; Deiters, A. Small-molecule inhibitors of microrna miR-21 function. Angew. Chem. Int. Ed., 2008, 47, 7482-7484.
-
(2008)
Angew. Chem. Int. Ed
, vol.47
, pp. 7482-7484
-
-
Gumireddy, K.1
Young, D.D.2
Xiong, X.3
Hogenesch, J.B.4
Huang, Q.5
Deiters, A.6
-
39
-
-
79952717616
-
Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing
-
Melo, S.; Villanueva, A.; Moutinho, C.; Davalos, V.; Spizzo, R.; Ivan, C.; Rossi, S.; Setien, F.; Casanovas, O.; Simo-Riudalbas, L.; Carmona, J.; Carrere, J.; Vidal, A.; Aytes, A.; Puertas, S.; Ropero, S.; Kalluri, R.; Croce, C.M.; Calin, G.A.; Esteller, M. Small molecule enoxacin is a cancer-specific growth inhibitor that acts by enhancing TAR RNA-binding protein 2-mediated microRNA processing. Proc. Natl. Acad. Sci. U. S. A., 2011, 108, 4394-4399.
-
(2011)
Proc. Natl. Acad. Sci. U. S. A
, vol.108
, pp. 4394-4399
-
-
Melo, S.1
Villanueva, A.2
Moutinho, C.3
Davalos, V.4
Spizzo, R.5
Ivan, C.6
Rossi, S.7
Setien, F.8
Casanovas, O.9
Simo-Riudalbas, L.10
Carmona, J.11
Carrere, J.12
Vidal, A.13
Aytes, A.14
Puertas, S.15
Ropero, S.16
Kalluri, R.17
Croce, C.M.18
Calin, G.A.19
Esteller, M.20
more..
-
40
-
-
77955287613
-
Identification of small molecules that suppress microRNA function and reverse tumorigenesis
-
Watashi, K.; Yeung, M.L.; Starost, M.F.; Hosmane, R.S.; Jeang, K.T. Identification of small molecules that suppress microRNA function and reverse tumorigenesis. J. Biol. Chem., 2010, 285, 24707-24716.
-
(2010)
J. Biol. Chem
, vol.285
, pp. 24707-24716
-
-
Watashi, K.1
Yeung, M.L.2
Starost, M.F.3
Hosmane, R.S.4
Jeang, K.T.5
-
41
-
-
84856650429
-
Pre-microRNA binding aminoglycosides and antitumor drugs as inhibitors of Dicer catalyzed microRNA processing
-
Maiti, M.; Nauwelaerts, K.; Herdewijn, P. Pre-microRNA binding aminoglycosides and antitumor drugs as inhibitors of Dicer catalyzed microRNA processing. Bioorg. Med. Chem. Lett., 2012, 22, 1709-1711.
-
(2012)
Bioorg. Med. Chem. Lett
, vol.22
, pp. 1709-1711
-
-
Maiti, M.1
Nauwelaerts, K.2
Herdewijn, P.3
-
42
-
-
84871027932
-
Xanthone derivatives as potential inhibitors of miRNA processing by human Dicer: Targeting secondary structures of pre-miRNA by small molecules
-
Murata, A.; Fukuzumi, T.; Umemoto, S.; Nakatani, K. Xanthone derivatives as potential inhibitors of miRNA processing by human Dicer: Targeting secondary structures of pre-miRNA by small molecules. Bioorg. Med. Chem. Lett., 2013, 23, 252-255.
-
(2013)
Bioorg. Med. Chem. Lett
, vol.23
, pp. 252-255
-
-
Murata, A.1
Fukuzumi, T.2
Umemoto, S.3
Nakatani, K.4
-
43
-
-
38049078739
-
A fluorescence probe for assaying micro RNA maturation
-
Davies, B.P.; Arenz, C. A fluorescence probe for assaying micro RNA maturation. Bioorg. Med. Chem., 2008, 16, 49-55.
-
(2008)
Bioorg. Med. Chem
, vol.16
, pp. 49-55
-
-
Davies, B.P.1
Arenz, C.2
-
44
-
-
66449100883
-
Short and efficient synthesis of alkyne-modified amino glycoside building blocks
-
Klemm, C.M.; Berthelmann, A.; Neubacher, S.; Arenz, C. Short and Efficient Synthesis of Alkyne-Modified Amino Glycoside Building Blocks. Eur. J. Org. Chem., 2009, 2788-2794.
-
(2009)
Eur. J. Org. Chem
, pp. 2788-2794
-
-
Klemm, C.M.1
Berthelmann, A.2
Neubacher, S.3
Arenz, C.4
-
45
-
-
22244467087
-
MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
-
Chan, J.A.; Krichevsky, A.M.; Kosik, K.S. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res., 2005, 65, 6029-6033.
-
(2005)
Cancer Res
, vol.65
, pp. 6029-6033
-
-
Chan, J.A.1
Krichevsky, A.M.2
Kosik, K.S.3
-
46
-
-
84856013951
-
The tuberculosis drug streptomycin as a potential cancer therapeutic: Inhibition of miR-21 function by directly targeting its precursor
-
Bose, D.; Jayaraj, G.; Suryawanshi, H.; Agarwala, P.; Pore, S.K.; Banerjee, R.; Maiti, S. The tuberculosis drug streptomycin as a potential cancer therapeutic: inhibition of miR-21 function by directly targeting its precursor. Angew. Chem. Int. Ed., 2012, 51, 1019-1023.
-
(2012)
Angew. Chem. Int. Ed
, vol.51
, pp. 1019-1023
-
-
Bose, D.1
Jayaraj, G.2
Suryawanshi, H.3
Agarwala, P.4
Pore, S.K.5
Banerjee, R.6
Maiti, S.7
-
47
-
-
23844523406
-
MiR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1
-
Chang, J.; Nicolas, E.; Marks, D.; Sander, C.; Lerro, A.; Buendia, M.A.; Xu, C.; Mason, W.S.; Moloshok, T.; Bort, R.; Zaret, K.S.; Taylor, J.M. miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1. RNA Biol., 2004, 1, 106-113.
-
(2004)
RNA Biol
, vol.1
, pp. 106-113
-
-
Chang, J.1
Nicolas, E.2
Marks, D.3
Sander, C.4
Lerro, A.5
Buendia, M.A.6
Xu, C.7
Mason, W.S.8
Moloshok, T.9
Bort, R.10
Zaret, K.S.11
Taylor, J.M.12
-
48
-
-
70450285075
-
MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib
-
Bai, S.; Nasser, M.W.; Wang, B.; Hsu, S.H.; Datta, J.; Kutay, H.; Yadav, A.; Nuovo, G.; Kumar, P.; Ghoshal, K. MicroRNA-122 inhibits tumorigenic properties of hepatocellular carcinoma cells and sensitizes these cells to sorafenib. J. Biol. Chem., 2009, 284, 32015-32027.
-
(2009)
J. Biol. Chem
, vol.284
, pp. 32015-32027
-
-
Bai, S.1
Nasser, M.W.2
Wang, B.3
Hsu, S.H.4
Datta, J.5
Kutay, H.6
Yadav, A.7
Nuovo, G.8
Kumar, P.9
Ghoshal, K.10
-
49
-
-
84883240474
-
MiR-122 Regulates Collagen Production via Targeting Hepatic Stellate Cells and Suppressing P4HA1 Expression
-
Li, J.; Ghazwani, M.; Zhang, Y.; Lu, J.; Li, J.; Fan, J.; Gandhi, C.R.; Li, S. miR-122 Regulates Collagen Production via Targeting Hepatic Stellate Cells and Suppressing P4HA1 Expression. J. Hepatol., 2012.
-
(2012)
J. Hepatol
-
-
Li, J.1
Ghazwani, M.2
Zhang, Y.3
Lu, J.4
Li, J.5
Fan, J.6
Gandhi, C.R.7
Li, S.8
-
50
-
-
84867597435
-
Hepatitis B Virus-Specific miRNAs and Argonaute2 Play a Role in the Viral Life Cycle
-
Hayes, C.N.; Akamatsu, S.; Tsuge, M.; Miki, D.; Akiyama, R.; Abe, H.; Ochi, H.; Hiraga, N.; Imamura, M.; Takahashi, S.; Aikata, H.; Kawaoka, T.; Kawakami, Y.; Ohishi, W.; Chayama, K. Hepatitis B Virus-Specific miRNAs and Argonaute2 Play a Role in the Viral Life Cycle. PLoS One, 2012, 7, e47490.
-
(2012)
PLoS One
, vol.7
-
-
Hayes, C.N.1
Akamatsu, S.2
Tsuge, M.3
Miki, D.4
Akiyama, R.5
Abe, H.6
Ochi, H.7
Hiraga, N.8
Imamura, M.9
Takahashi, S.10
Aikata, H.11
Kawaoka, T.12
Kawakami, Y.13
Ohishi, W.14
Chayama, K.15
-
51
-
-
84876378510
-
MiR-122 participates in the cell tropism of hepatitis C virus
-
Fukuhara, T.; Matsuura, Y. [miR-122 participates in the cell tropism of hepatitis C virus]. Uirusu, 2012, 62, 1-8.
-
(2012)
Uirusu
, vol.62
, pp. 1-8
-
-
Fukuhara, T.1
Matsuura, Y.2
-
52
-
-
84862777271
-
MicroRNA-122 suppresses cell proliferation and induces cell apoptosis in hepatocellular carcinoma by directly targeting Wnt/betacatenin pathway
-
Xu, J.; Zhu, X.; Wu, L.; Yang, R.; Yang, Z.; Wang, Q.; Wu, F. MicroRNA-122 suppresses cell proliferation and induces cell apoptosis in hepatocellular carcinoma by directly targeting Wnt/betacatenin pathway. Liver Int., 2012, 32, 752-760.
-
(2012)
Liver Int
, vol.32
, pp. 752-760
-
-
Xu, J.1
Zhu, X.2
Wu, L.3
Yang, R.4
Yang, Z.5
Wang, Q.6
Wu, F.7
-
53
-
-
84864773072
-
MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis
-
Tsai, W.C.; Hsu, S.D.; Hsu, C.S.; Lai, T.C.; Chen, S.J.; Shen, R.; Huang, Y.; Chen, H.C.; Lee, C.H.; Tsai, T.F.; Hsu, M.T.; Wu, J.C.; Huang, H.D.; Shiao, M.S.; Hsiao, M.; Tsou, A.P. MicroRNA-122 plays a critical role in liver homeostasis and hepatocarcinogenesis. J. Clin. Invest., 2012, 122, 2884-2897.
-
(2012)
J. Clin. Invest
, vol.122
, pp. 2884-2897
-
-
Tsai, W.C.1
Hsu, S.D.2
Hsu, C.S.3
Lai, T.C.4
Chen, S.J.5
Shen, R.6
Huang, Y.7
Chen, H.C.8
Lee, C.H.9
Tsai, T.F.10
Hsu, M.T.11
Wu, J.C.12
Huang, H.D.13
Shiao, M.S.14
Hsiao, M.15
Tsou, A.P.16
-
54
-
-
84862743241
-
A daphnane diterpenoid isolated from Wikstroemia polyantha induces an inflammatory response and modulates miRNA activity
-
Khong, A.; Forestieri, R.; Williams, D.E.; Patrick, B.O.; Olmstead, A.; Svinti, V.; Schaeffer, E.; Jean, F.; Roberge, M.; Andersen, R.J.; Jan, E. A daphnane diterpenoid isolated from Wikstroemia polyantha induces an inflammatory response and modulates miRNA activity. PLoS One, 2012, 7, e39621.
-
(2012)
PLoS One
, vol.7
-
-
Khong, A.1
Forestieri, R.2
Williams, D.E.3
Patrick, B.O.4
Olmstead, A.5
Svinti, V.6
Schaeffer, E.7
Jean, F.8
Roberge, M.9
Andersen, R.J.10
Jan, E.11
-
55
-
-
84655167637
-
Aza-Flavanones as potent cross-species microRNA inhibitors that arrest cell cycle
-
Chandrasekhar, S.; Pushpavalli, S.N.; Chatla, S.; Mukhopadhyay, D.; Ganganna, B.; Vijeender, K.; Srihari, P.; Reddy, C.R.; Janaki Ramaiah, M.; Bhadra, U. aza-Flavanones as potent cross-species microRNA inhibitors that arrest cell cycle. Bioorg. Med. Chem. Lett., 2012, 22, 645-648.
-
(2012)
Bioorg. Med. Chem. Lett
, vol.22
, pp. 645-648
-
-
Chandrasekhar, S.1
Pushpavalli, S.N.2
Chatla, S.3
Mukhopadhyay, D.4
Ganganna, B.5
Vijeender, K.6
Srihari, P.7
Reddy, C.R.8
Janaki Ramaiah, M.9
Bhadra, U.10
-
56
-
-
38149042783
-
Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells
-
Frankel, L.B.; Christoffersen, N.R.; Jacobsen, A.; Lindow, M.; Krogh, A.; Lund, A.H. Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J. Biol. Chem., 2008, 283, 1026-1033.
-
(2008)
J. Biol. Chem
, vol.283
, pp. 1026-1033
-
-
Frankel, L.B.1
Christoffersen, N.R.2
Jacobsen, A.3
Lindow, M.4
Krogh, A.5
Lund, A.H.6
-
57
-
-
42149192536
-
PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains
-
Suzuki, C.; Garces, R.G.; Edmonds, K.A.; Hiller, S.; Hyberts, S.G.; Marintchev, A.; Wagner, G. PDCD4 inhibits translation initiation by binding to eIF4A using both its MA3 domains. Proc. Natl. Acad. Sci. U. S. A., 2008, 105, 3274-3279.
-
(2008)
Proc. Natl. Acad. Sci. U. S. A
, vol.105
, pp. 3274-3279
-
-
Suzuki, C.1
Garces, R.G.2
Edmonds, K.A.3
Hiller, S.4
Hyberts, S.G.5
Marintchev, A.6
Wagner, G.7
-
58
-
-
74249112787
-
Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection
-
Lanford, R.E.; Hildebrandt-Eriksen, E.S.; Petri, A.; Persson, R.; Lindow, M.; Munk, M.E.; Kauppinen, S.; Orum, H. Therapeutic silencing of microRNA-122 in primates with chronic hepatitis C virus infection. Science, 2010, 327, 198-201.
-
(2010)
Science
, vol.327
, pp. 198-201
-
-
Lanford, R.E.1
Hildebrandt-Eriksen, E.S.2
Petri, A.3
Persson, R.4
Lindow, M.5
Munk, M.E.6
Kauppinen, S.7
Orum, H.8
-
59
-
-
72849125318
-
Modulation of hepatitis C virus RNA abundance and the isoprenoid biosynthesis pathway by microRNA miR-122 involves distinct mechanisms
-
Norman, K.L.; Sarnow, P. Modulation of hepatitis C virus RNA abundance and the isoprenoid biosynthesis pathway by microRNA miR-122 involves distinct mechanisms. J. Virol., 2010, 84, 666-670.
-
(2010)
J. Virol
, vol.84
, pp. 666-670
-
-
Norman, K.L.1
Sarnow, P.2
-
60
-
-
50849115468
-
MiR-122 targets an anti-apoptotic gene, Bcl-w, in human hepatocellular carcinoma cell lines
-
Lin, C.J.; Gong, H.Y.; Tseng, H.C.; Wang, W.L.; Wu, J.L. miR-122 targets an anti-apoptotic gene, Bcl-w, in human hepatocellular carcinoma cell lines. Biochem. Biophys. Res. Commun., 2008, 375, 315-320.
-
(2008)
Biochem. Biophys. Res. Commun
, vol.375
, pp. 315-320
-
-
Lin, C.J.1
Gong, H.Y.2
Tseng, H.C.3
Wang, W.L.4
Wu, J.L.5
-
61
-
-
46249107572
-
Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells
-
Mudhasani, R.; Zhu, Z.; Hutvagner, G.; Eischen, C.M.; Lyle, S.; Hall, L.L.; Lawrence, J.B.; Imbalzano, A.N.; Jones, S.N. Loss of miRNA biogenesis induces p19Arf-p53 signaling and senescence in primary cells. J. Cell Biol., 2008, 181, 1055-1063.
-
(2008)
J. Cell Biol
, vol.181
, pp. 1055-1063
-
-
Mudhasani, R.1
Zhu, Z.2
Hutvagner, G.3
Eischen, C.M.4
Lyle, S.5
Hall, L.L.6
Lawrence, J.B.7
Imbalzano, A.N.8
Jones, S.N.9
-
62
-
-
33947236349
-
Up-regulation of dicer, a component of the MicroRNA machinery, in prostate adenocarcinoma
-
Chiosea, S.; Jelezcova, E.; Chandran, U.; Acquafondata, M.; McHale, T.; Sobol, R.W.; Dhir, R. Up-regulation of dicer, a component of the MicroRNA machinery, in prostate adenocarcinoma. Am. J. Pathol., 2006, 169, 1812-1820.
-
(2006)
Am. J. Pathol
, vol.169
, pp. 1812-1820
-
-
Chiosea, S.1
Jelezcova, E.2
Chandran, U.3
Acquafondata, M.4
McHale, T.5
Sobol, R.W.6
Dhir, R.7
-
63
-
-
55349109615
-
Roles for microRNAs, miR-93 and miR-130b, and tumor protein 53-induced nuclear protein 1 tumor suppressor in cell growth dysregulation by human Tcell lymphotrophic virus 1
-
Yeung, M.L.; Yasunaga, J.; Bennasser, Y.; Dusetti, N.; Harris, D.; Ahmad, N.; Matsuoka, M.; Jeang, K.T. Roles for microRNAs, miR-93 and miR-130b, and tumor protein 53-induced nuclear protein 1 tumor suppressor in cell growth dysregulation by human Tcell lymphotrophic virus 1. Cancer Res., 2008, 68, 8976-8985.
-
(2008)
Cancer Res
, vol.68
, pp. 8976-8985
-
-
Yeung, M.L.1
Yasunaga, J.2
Bennasser, Y.3
Dusetti, N.4
Harris, D.5
Ahmad, N.6
Matsuoka, M.7
Jeang, K.T.8
-
64
-
-
76649105418
-
MicroRNA function in cancer: Oncogene or a tumor suppressor?
-
Shenouda, S.K.; Alahari, S.K. MicroRNA function in cancer: oncogene or a tumor suppressor? Cancer Metastasis Rev., 2009, 28, 369-378.
-
(2009)
Cancer Metastasis Rev
, vol.28
, pp. 369-378
-
-
Shenouda, S.K.1
Alahari, S.K.2
-
65
-
-
84871397454
-
Selective targeting of distinct active site nucleophiles by irreversible Src-family kinase inhibitors
-
Gushwa, N.N.; Kang, S.; Chen, J.; Taunton, J. Selective Targeting of Distinct Active Site Nucleophiles by Irreversible Src-Family Kinase Inhibitors. J. Am. Chem. Soc., 2012, 134, 20214-20217.
-
(2012)
J. Am. Chem. Soc
, vol.134
, pp. 20214-20217
-
-
Gushwa, N.N.1
Kang, S.2
Chen, J.3
Taunton, J.4
-
66
-
-
84871376577
-
Suite of activity-based probes for cellulose-degrading enzymes
-
Chauvigne-Hines, L.M.; Anderson, L.N.; Weaver, H.M.; Brown, J.N.; Koech, P.K.; Nicora, C.D.; Hofstad, B.A.; Smith, R.D.; Wilkins, M.J.; Callister, S.J.; Wright, A.T. Suite of Activity-Based Probes for Cellulose-Degrading Enzymes. J. Am. Chem. Soc., 2012, 134, 20521-20532.
-
(2012)
J. Am. Chem. Soc
, vol.134
, pp. 20521-20532
-
-
Chauvigne-Hines, L.M.1
Anderson, L.N.2
Weaver, H.M.3
Brown, J.N.4
Koech, P.K.5
Nicora, C.D.6
Hofstad, B.A.7
Smith, R.D.8
Wilkins, M.J.9
Callister, S.J.10
Wright, A.T.11
-
67
-
-
84872728103
-
Design, functionalization strategies and biomedical applications of targeted biodegradable/biocompatible polymer-based nanocarriers for drug delivery
-
Nicolas, J.; Mura, S.; Brambilla, D.; Mackiewicz, N.; Couvreur, P. Design, functionalization strategies and biomedical applications of targeted biodegradable/biocompatible polymer-based nanocarriers for drug delivery. Chem. Soc. Rev., 2012, 42, 1147-1235.
-
(2012)
Chem. Soc. Rev
, vol.42
, pp. 1147-1235
-
-
Nicolas, J.1
Mura, S.2
Brambilla, D.3
Mackiewicz, N.4
Couvreur, P.5
-
68
-
-
84864130324
-
Mucus penetrating nanoparticles: Biophysical tool and method of drug and gene delivery
-
Ensign, L.M.; Schneider, C.; Suk, J.S.; Cone, R.; Hanes, J. Mucus penetrating nanoparticles: biophysical tool and method of drug and gene delivery. Adv. Mater., 2012, 24, 3887-3894.
-
(2012)
Adv. Mater
, vol.24
, pp. 3887-3894
-
-
Ensign, L.M.1
Schneider, C.2
Suk, J.S.3
Cone, R.4
Hanes, J.5
|