Pre-microRNA binding aminoglycosides and antitumor drugs as inhibitors of Dicer catalyzed microRNA processing

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 4, 2012, Pages 1709-1711

  Maiti, Mohitosh ^a   Nauwelaerts, Koen ^a   Herdewijn, Piet ^a  

^a REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

Dicer assay; Inhibitors; Micro RNA; RNA recognition; Structure activity relationships

Indexed keywords

4',6 DIAMIDINO 2 PHENYLINDOLE; AMINOGLYCOSIDE; ANTINEOPLASTIC AGENT; APRAMYCIN; BERBERINE; BLEOMYCIN; DACTINOMYCIN; DAUNORUBICIN; DICER; DOXORUBICIN; ETHIDIUM; FRAMYCETIN; KANAMYCIN A; KANAMYCIN B; MEPACRINE; MICRORNA; NEOMYCIN; PROFLAVINE; VANCOMYCIN;

ARTICLE; CATALYSIS; CONTROLLED STUDY; DRUG RECEPTOR BINDING; ENZYME INHIBITION; MOLECULAR THERAPY; PROTEIN CLEAVAGE; RNA BINDING; RNA PROCESSING;

EID: 84856650429     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2011.12.103     Document Type: Article

References (34)

1. Lee, R. C.; Feinbaum, R. L.; Ambros, V. Cell 1993, 75, 843.
2. Ambros, V. Nature 2004, 431, 350.
3. He, L.; Hannon, G. J. Nat. Rev. Genet. 2004, 5, 522.
4. Bartel, D. P. Cell 2004, 116, 281.
5. Gregory, R. I.; Shiekhattar, R. Cancer Res. 2005, 65, 3509.
6. Wiemer, E. A. Eur. J. Cancer 2007, 43, 1529.
7. Couzin, J. Science 2008, 319, 1782.
8. Garofalo, M.; Croce, C. M. Annu. Rev. Pharmacol. Toxicol. 2011, 51, 25.
9. Meister, G.; Landthaler, M.; Dorsett, Y.; Tuschl, T. RNA 2004, 10, 544.
10. Davis, S.; Lollo, B.; Freier, S.; Esau, C. Nucleic Acids Res. 2006, 34, 2294.
11. Hammond, S. M. Trends Mol. Med. 2006, 12, 99.
12. Garzon, R.; Marcucci, G.; Croce, C. M. Nat. Rev. Drug Disc. 2010, 9, 775.
13. Xu, L.; Anchordoquy, T. J. Pharm. Sci. 2011, 100, 38.
14. Gumireddy, K.; Young, D. D.; Xiong, X.; Hogenesch, J. B.; Huang, Q.; Deiters, A. Angew. Chem. Int. Ed. 2008, 47, 7482.
15. Watashi, K.; Yeung, M. L.; Starost, M. F.; Hosmane, R. S.; Jeang, K. T. J. Biol. Chem. 2010, 285, 24707.
16. Young, D. D.; Connelly, C. M.; Grohmann, C.; Deiters, A. J. Am. Chem. Soc. 2010, 132, 7976.
17. Deiters, A. AAPS J. 2010, 12, 51.
18. Li, Y.; He, C.; Jin, P. Chem. Biol. 2010, 17, 584.
19. Elbashir, S. M.; Lendeckel, W.; Tuschl, T. Genes Dev. 2001, 15, 188.
20. Provost, P.; Dishart, D.; Doucet, J.; Frendewey, D.; Samuelsson, B.; Radmark, O. EMBO J. 2002, 21, 5864.
21. Bosse, G. D.; Simard, M. J. Cell Res. 2010, 20, 735.
22. Davies, B. P.; Arenz, C. Angew. Chem. Int. Ed. 2006, 45, 5550.
23. Davies, B. P.; Arenz, C. Bioorg. Med. Chem. 2007, 16, 49.
24. Thomas, J. R.; Hergenrother, P. J. Chem. Rev. 2008, 108, 1171.
25. Krishnamurthy, M.; Simon, K.; Orendt, A. M.; Beal, P. A. Angew. Chem. Int. Ed. 2007, 46, 7044.
26. Chirayil, S.; Chirayil, R.; Luebke, K. J. Nucleic Acids Res. 2009, 37, 5486.
27. Kotra, L. P.; Haddad, J.; Mobashery, S. Antimicrob. Agents Chemother. 2000, 44, 3249.
28. Nitiss, J. L. Nat. Rev. Cancer 2009, 9, 338.
29. Sobell, H. M. Proc. Natl. Acad. Sci. U.S.A. 1985, 82, 5328.
30. Rodriguez, A.; Vigorito, E.; Clare, S.; Warren, M. V.; Couttet, P.; Soond, D. R.; van Dongen, S.; Grocock, R. J.; Das, P. P.; Miska, E. A.; Vetrie, D.; Okkenhaug, K.; Enright, A. J.; Dougan, G.; Turner, M.; Bradley, A. Science 2007, 316, 608.
31. Costinean, S.; Zanesi, N.; Pekarsky, Y.; Tili, E.; Volinia, S.; Heerema, N.; Croce, C. M. Proc. Natl. Acad. Sci. U.S.A. 2006, 103, 7024.
32. Chaltin, P.; Borgions, F.; Van Aerschot, A.; Herdewijn, P. Bioorg. Med. Chem. Lett. 2003, 13, 47.
33. Gallego, J.; Varani, G. Acc. Chem. Res. 2001, 34, 836.
34. Shaw, N. N.; Xi, H.; Arya, D. P. Bioorg. Med. Chem. Lett. 2008, 18, 4142.