Physicochemical, pharmaceutical and biological approaches toward designing optimized and efficient hydrophobically modified chitosan-based polymeric micelles as a nanocarrier system for targeted delivery of anticancer drugs

Journal of Drug Targeting

Volumn 21, Issue 8, 2013, Pages 693-709

  Mahmoudzadeh, Mohammad ^a   Fassihi, Afshin ^a   Emami, Jaber ^a   Davies, Neal M ^b   Dorkoosh, Farid ^c  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b UNIVERSITY OF MANITOBA   (Canada)

^c TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Chitosan; Drug targeting; Hydrophilic segment; Hydrophobic segment; Polymeric micelles

Indexed keywords

ANTINEOPLASTIC AGENT; CAMPTOTHECIN; CHITOSAN BASED POLYMERIC MICELLE; CHITOSAN DERIVATIVE; DEOXYCHOLIC ACID; DOXORUBICIN; FLUORESCEIN ISOTHIOCYANATE CONJUGATED GLYCOL CHITOSAN; FOLIC ACID; GLUTARALDEHYDE; MACROGOL; N OCTYL N PHTHALYL 3,6 O (2 HYDROXYPROPYL)CHITOSAN; N SUCCINYL N' OCTYLCHITOSAN; NANOCARRIER; OCTREOTIDE; PACLITAXEL; POLYCAPROLACTONE; POLYMER; STEARIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL COMPOSITION; CHEMICAL INTERACTION; CHEMICAL MODIFICATION; CONFORMATIONAL TRANSITION; CYTOPATHOGENIC EFFECT; DRUG ABSORPTION; DRUG ACCUMULATION; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HYDROPHOBICITY; MICELLE; MOLECULARLY TARGETED THERAPY; NONHUMAN; PHYSICAL CHEMISTRY; PRIORITY JOURNAL;

ANIMALS; ANTINEOPLASTIC AGENTS; CHITOSAN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MICELLES; NANOPARTICLES; POLYMERS;

EID: 84883219604     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.3109/1061186X.2013.824455     Document Type: Article

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