Preparation, characterization, and in vitro drug release behavior of 6-mercaptopurine-carboxymethyl chitosan

Carbohydrate Polymers

Volumn 83, Issue 4, 2011, Pages 1952-1958

  Zheng, Hua ^a   Rao, Yan ^a   Yin, Yihua ^a   Xiong, Xiong ^a   Xu, Peihu ^a   Lu, Bo ^a  

^a WUHAN UNIVERSITY OF TECHNOLOGY   (China)

Author keywords

6 Mercaptopurine; Carboxymethyl chitosan; GSH dependent release kinetics

Indexed keywords

6-MERCAPTOPURINE; BUFFER PH; BUFFER SOLUTIONS; CARBOXYMETHYL CHITOSAN; GLUTATHIONES; HYDRODYNAMIC DIAMETER; IN-VITRO; RELEASE KINETICS; RELEASE RATE; SELF-ASSEMBLE; TEM;

BIOLOGICAL MEMBRANES; CHITIN; CHITOSAN; DYNAMIC LIGHT SCATTERING; HYDROGELS; MULTILAYERS; SELF ASSEMBLY; TRANSMISSION ELECTRON MICROSCOPY;

DRUG PRODUCTS;

EID: 78650519892     PISSN: 01448617     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.carbpol.2010.10.069     Document Type: Article

References (23)

1. F.R. Abreu, and S.P. Campana-Filho Preparation and characterization of carboxymethyl chitosan Polímeros: Ciênciae Tecnologia 15 2005 79 83
2. F.R. Abreu, and S.P. Campana-Filho Characteristics and properties of carboxymethylchitosan Carbohydrate Polymers 75 2009 214 221
3. K. Akiyoshi, S. Deguchi, H. Tajima, T. Nishikawa, and J. Sunamoto Microscopic structure and thermoresponsiveness of a hydrogel nanoparticle by self-assembly of a hydrophobized polysaccharide Macromolecules 30 1997 857 861
4. B.A. Arrick, and C.F. Nathan Glutathione metabolism as a determinant of therapeutic efficacy: A review Cancer Research 44 1984 4224 4232
5. L. Aubry, G. Klein, J.L. Martiel, and M. Satre Kinetics of endosomal pH evolution in Dictyostelium discoideum amoebae Study by uorescence spectroscopy Journal of Cell Science 105 1993 861 866
6. S.F. Chong, R. Chandrawati, B. Städler, J. Park, J.H. Cho, and Y.J. Wang Stabilization of polymer-hydrogel capsules via thiol-disulde exchange Polymer-Hydrogel Capsules 22 5 2009 2601 2610
7. W.W. Cleland Dithiothreitol, a new protective reagent for SH groups Biochemistry 3 4 1964 480 482
8. G. Gaucher, M.H. Dufresne, V.P. Sant, N. Kang, D. Maysinger, and J.C. Leroux Block copolymer micelles: Preparation, characterization and application in drug delivery Journal of Controlled Release 109 2005 169 188
9. Y Hu, X.R. He, L. Lei, Sh.C. Liang, G.F. Qiu, and X.M. Hu Preparation and characterization of self-assembled nanoparticles of the novel carboxymethyl pachyman-deoxycholic acid conjugates Carbohydrate Polymers 74 2008 220 227
10. K. Kataoka, A. Harada, and Y. Nagasaki Block copolymer micelles for drug delivery: Design, characterization and biological signicance Advanced Drug Delivery Reviews 47 2001 113 131
11. N.J. Kavimandan, E. Losi, J.J. Wilson, J.S. Brodbelt, and N.A. Peppas Synthesis and characterization of insulin-transferrin conjugates Bioconjugate Chemistry 17 2006 1376 1384
12. E. Lee, H. Kim, I.H. Lee, and S. Jon In vivo antitumor effects of chitosan-conjugated docetaxel after oral administration Journal of Controlled Release 140 2009 79 85
13. Ch.G. Liu, W.W. Fan, X.G. Chen, Ch.Sh. Liu, X.H. Meng, and J.P. Hyun Self-assembled nanoparticles based on linoleic-acid modified carboxymethyl-chitosan as carrier of adriamycin (ADR) Current Applied Physics 7S 1 2007 e125 e129
14. K.H. Liu, S.Y. Chen, D.M. Liu, and T.Y. Liu Self-Assembled hollow nanocapsule from amphiphatic carboxymethyl-hexanoyl chitosan as drug carrier Macromolecules 41 2008 6511 6516
15. A. Meister, and M.E. Anderson Glutathione Annual Review of Biochemistry 52 1983 711 760
16. W.P. Sui, S.F. Wang, G.H. Chen, and G.Y. Xu Surface and aggregate properties of an amphiphilic derivative of carboxymethyl chitosan Carbohydrate Research 339 2004 1113 1118
17. Y.S. Wang, Q. Jiang, R.Sh. Li, L.L. Liu, Q.Q. Zhang, Y.M. Wang, and J. Zhao Self-assembled nanoparticles of cholesterol-modified O-carboxymethyl chitosan as a novel carrier for paclitaxel Nanotechnology 19 2008 145101
18. Y.S. Wang, L.R. Liu, W. Jian, and Q.Q. Zhang Preparation and characterization of self-aggregated nanoparticles of cholesterol-modified O-carboxymethyl chitosan conjugates Carbohydrate Polymers 69 2007 597 606
19. C.C. Winterbourn, and D. Metodiewa Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide Free Radical Biology & Medicine 27 1999 322 328
20. Y.M. Xie, and J. He Synthesis of N,O-carboxylchitosan-doxorubicin conjugates and research of their properties 2006 Sichuan University (in Chinese)
21. L. Yang, R. Zeng, Ch. Li, G. Li, R.Zh. Qiao, L.M. Hu, and Z.L. Li Novel synthesis and in vitro drug release of polymeric prodrug: Chitosan-O-isopropyl- 50-O-d4T monophosphate conjugate Bioorganic and Medicinal Chemistry Letters 19 2009 2566 2569
22. C.C. Yeh, M.F. Hou, S.H. Wu, S.M. Tsai, S.K. Lin, L.A. Hou, H. Ma, and L.Y. Tsai A study of glutathione status in the blood and tissues of patients with breast cancer Cell Biochemistry and Function 24 2006 555 559
23. M. Zacchigna, F. Cateni, G. Di-Luca, and S. Drioli A simple method for the preparation of PEG-6-mercaptopurine for oral administration Bioorganic and Medicinal Chemistry Letters 17 2007 6607 6609