Tumor targeting efficiency of bare nanoparticles does not mean the efficacy of loaded anticancer drugs: Importance of radionuclide imaging for optimization of highly selective tumor targeting polymeric nanoparticles with or without drug

Journal of Controlled Release

Volumn 147, Issue 2, 2010, Pages 253-260

  Lee, Beom Suk ^a   Park, Kyeongsoon ^b   Park, Sangjin ^b   Kim, Gui Chul ^a   Kim, Hyo Jung ^a   Lee, Sangjoo ^a   Kil, Heeseup ^c   Oh, Seung Jun ^a   Chi, Daeyoon ^c   Kim, Kwangmeyung ^b   Choi, KuiWon ^b   Kwon, Ick Chan ^b   Kim, Sang Yoon ^a  

^a University of Ulsan College of Medicine   (South Korea)

^b Korea Institute of Science and Technology   (South Korea)

^c Sogang University   (South Korea)

Author keywords

Biodistributions; Drug delivery; Gamma camera; NAcHis GC; Near infrared fluorescence; Non invasive imaging

Indexed keywords

BIODISTRIBUTIONS; GAMMA CAMERAS; NACHIS-GC; NEAR-INFRARED FLUORESCENCE; NON-INVASIVE IMAGING;

ANIMALS; CAMERAS; DRUG DELIVERY; FLUORESCENCE; FUNCTIONAL POLYMERS; GLYCOLS; HYDROPHOBICITY; INFRARED DEVICES; PHOSPHATASES; POLYMERS; TUMORS;

NANOPARTICLES;

ANTINEOPLASTIC AGENT; CHITOSAN; DOXORUBICIN; N ACETYLHISTIDINE 1 I 131; N ACETYLHISTIDINE 2 I 131; N ACETYLHISTIDINE 3 I 131; NANOPARTICLE; POLYMER; RADIOPHARMACEUTICAL AGENT; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG EFFECT; DRUG EFFICACY; DRUG RELEASE; DRUG STABILITY; DRUG TARGETING; EXPERIMENTAL MODEL; GAMMA SCINTIGRAPHY; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MOLECULAR IMAGING; MOUSE; NEAR INFRARED SPECTROSCOPY; NON INVASIVE PROCEDURE; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE;

ANIMALS; ANTINEOPLASTIC AGENTS; CHITOSAN; DOXORUBICIN; DRUG CARRIERS; HISTIDINE; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MALE; MICE; MICE, NUDE; MODELS, MOLECULAR; MOLECULAR STRUCTURE; NANOPARTICLES; NEOPLASMS; RADIONUCLIDE IMAGING; TISSUE DISTRIBUTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 77957018483     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2010.07.096     Document Type: Article

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