Hydrophobically modified glycol chitosan nanoparticles as carriers for paclitaxel

Journal of Controlled Release

Volumn 111, Issue 1-2, 2006, Pages 228-234

  Kim, Jong Ho ^a   Kim, Yoo Shin ^b,c   Kim, Sungwon ^a   Park, Jae Hyung ^d   Kim, Kwangmeyung ^a   Choi, Kuiwon ^a   Chung, Hesson ^a   Jeong, Seo Young ^d   Park, Rang Woon ^b,c   Kim, In San ^b,c   Kwon, Ick Chan ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Kyungpook National University School of Medicine   (South Korea)

^c Advanced Medical Technology Cluster for Diagnosis and Prediction   (South Korea)

^d Kyung Hee University   (South Korea)

Author keywords

Hydrophobically modified glycol chitosan; In vivo anti tumor effect; Nanoparticles; Paclitaxel

Indexed keywords

CHITIN; PH EFFECTS; SELF ASSEMBLY; SYNTHESIS (CHEMICAL); THERMODYNAMICS; TOXICITY;

HYDROPHOBICALLY MODIFIED GLYCOL CHITOSAN; IN VIVO ANTI-TUMOR EFFECT; NANOPARTICLES; PACLITAXE;

NANOSTRUCTURED MATERIALS;

1 (3 DIMETHYLAMINOPROPYL) 3 ETHYLCARBODIIMIDE; ANTINEOPLASTIC AGENT; CHITOSAN DERIVATIVE; CHOLANIC ACID DERIVATIVE; DRUG CARRIER; GLYCOL CHITOSAN; PACLITAXEL; PHOSPHATE; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; CANCER; CANCER INHIBITION; CANCER PREVENTION; CONFERENCE PAPER; CONTROLLED STUDY; CYTOTOXICITY; DIALYSIS; DOSE RESPONSE; DRUG FORMULATION; DRUG STABILITY; DRUG STRUCTURE; HUMAN; HUMAN CELL; HUMAN TISSUE; HYDROPHOBICITY; MALE; MELANOMA; MELANOMA CELL; MOUSE; MOUSE STRAIN; NANOPARTICLE; NONHUMAN; PRIORITY JOURNAL; SUSTAINED DRUG RELEASE; THERMODYNAMICS; TUMOR VOLUME;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BODY WEIGHT; CELL LINE, TUMOR; CELL SURVIVAL; CHITOSAN; DRUG CARRIERS; GLYCEROL; HUMANS; HYDROPHOBICITY; INJECTIONS, INTRAVENOUS; MALE; MELANOMA, EXPERIMENTAL; MICE; MICE, INBRED C57BL; NANOSTRUCTURES; PACLITAXEL; TECHNOLOGY, PHARMACEUTICAL; TIME FACTORS; TREATMENT OUTCOME;

EID: 33344466821     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2005.12.013     Document Type: Conference Paper

References (28)

1. D.G.I. Kingston The chemistry of taxol Pharmacol. Ther. 52 1991 1 34
2. C.M. Spencer, and D. Faulds Paclitaxel: a review of its pharmacodynamic and pharmacokinetic properties and therapeutic potential in the treatment of cancer Drugs 48 1994 782 794
3. E.K. Rowinsky, N. Onetto, R.M. Canetta, and S.G. Arbuck Taxol: the first of the taxanes, an important new class of antitumor agents Semin. Oncol. 19 1992 646 662
4. R.C. Lilenbaum, and M.R. Green Novel chemotherapeutic agents in the treatment of non-small cell lung cancer J. Clin. Oncol. 11 1993 1391 1402
5. J.T. Thipgen, J.A. Blessing, H. Ball, S.J. Hummel, and R.J. Barrett Phase II trial of paclitaxel in patients with progressive ovarian carcinoma after platinum-based chemotherapy: a gynaecologic oncology group study J. Clin. Oncol. 12 1994 1748 1753
6. V. Martin Overview of paclitaxel (Taxol) Semin. Oncol. Nurs. 9 1993 2 5
7. N. Onetto, R. Canett, B. Winograd, R. Catane, M. Cougan, and J. Grechko Overview of taxol safety J. Natl. Cancer Inst. Monographs 15 1993 131 139
8. D. Mazzo, J.J. Nguyen Huu, S. Pagniez, and P. Denis Compatibility of docetaxel and paclitaxel in intravenous solutions with polyvinyl chloride infusion materials Am. J. Health-Syst. Pharm. 54 1997 566 569
9. R. Gregory, and A.F. DeLisa Paclitaxel: a new antineoplastic agent for refractory ovarian cancer Clin. Pharm. 12 1993 401 415
10. A. Krishnadas, U. Rubinstein, and H. Onyuksel Sterically stabilized phospholipids mixed micelles: in vitro evaluation as a novel carrier for water insoluble drugs Pharm. Res. 20 2003 297 302
11. R. Duncan The dawning era of polymer therapeutics Nat. Rev. Drug Discov. 2 2003 347 359
12. G.S. Kwon Polymeric micelles for delivery poorly water-soluble compounds Crit. Rev. Ther. Drug Carr. Syst. 20 2003 357 403
13. H.S. Yoo, and T.G. Park Folate receptor targeted biodegradable polymeric doxorubicin micelles J. Control. Release 96 2004 273 283
14. E.S. Lee, H.J. Shin, K. Na, and Y.H. Bae Poly(l-histidine)-PEG block copolymer micelles and pH-induced destabilization J. Control. Release 90 2003 363 374
15. Y. Matsumura, and H. Maeda A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and antitumor agent smancs Cancer Res. 46 1986 6387 6392
16. G.S. Kwon, M. Naito, M. Yokoyama, T. Okano, Y. Sakurai, and K. Kataoka Physical entrapment of adriamycin in AB block copolymer micelles Pharm. Res. 12 1995 192 195
17. M. Yokoyama, M. Miyauchi, N. Yamada, T. Okano, Y. Sakurai, K. Kataoka, and S. Inoue Characterization and anticancer activity of the micelle-forming polymeric anticancer drug adriamycin-conjugated poly(ethylene glycol)-poly(aspartic acid) block copolymer Cancer Res. 50 1990 1693 1700
18. H. Hashizume, P. Baluk, S. Morikawa, J.W. McLean, G. Thurston, S. Roberge, R.K. Jain, and D.M. McDonald Openings between defective endothelial cells explain tumor vessel leakiness Am. J. Pathol. 156 2000 1363 1380
19. V.R. Sinha, A.K. Singla, S. Wadhawan, R. Kaushik, R. Kumria, K. Nansal, and S. Dhawan Chitosan microspheres as a potential carrier for drugs Int. J. Pharm. 274 2004 1 33
20. M.J. Alonso, and A. Sanchez The potential of chitosan in ocular drug delivery J. Pharm. Pharmacol. 55 2003 1451 1463
21. J.H. Park, Y.W. Cho, H. Chung, I.C. Kwon, and S.Y. Jeong Synthesis and characterization of sugar-bearing chitosan derivatives: aqueous solubility and biodegradability Biomacromolecules 4 2003 1087 1091
22. S. Kwon, J.H. Park, H. Chung, I.C. Kwon, and S.Y. Jeong Physicochemical characteristics of self-assembled nanoparticles based on glycol chitosan bearing 5β-cholanic acid Langmuir 19 2003 10188 10193
23. A. Enhsen, W. Kramer, and G. Wess Bile acids in drug delivery Drug Discov. Today 3 1998 409 418
24. R.C. Allison, P.V. Carlile Jr., and B.A. Gray Thermodilution measurement of lung water Clin. Chest Med. 6 1985 439 457
25. K. Kim, S. Kwon, J.H. Park, H. Chung, S.Y. Jeong, I.C. Kwon, and I.S. Kim Physicochemical characterizations of self-assembled nanoparticles of glycol chitosan-deoxycholic acid conjugates Biomacromolecules 6 2005 1154 1158
26. S.C. Lee, C. Kim, I.C. Kwon, H. Chung, and S.Y. Jeong Polymeric micelles of poly(2-ethyl-2-oxazoline)-block-poly(e-caprolactone) copolymer as a carrier for paclitaxel J. Control. Release 89 2003 437 446
27. S.C. Kim, D.W. Kim, Y.H. Shim, J.S. Bang, H.S. Oh, S.W. Kim, and M.H. Seo In vivo evaluation of polymeric micellar paclitaxel formulation: toxicity and efficacy J. Control. Release 72 2001 191 202
28. R.T. Dorr Pharmacology and toxicology of Cremophor EL diluent Ann. Pharmacother. 28 1994 S11 S14