N-acetyl histidine-conjugated glycol chitosan self-assembled nanoparticles for intracytoplasmic delivery of drugs: Endocytosis, exocytosis and drug release

Journal of Controlled Release

Volumn 115, Issue 1, 2006, Pages 37-45

  Park, Ji Sun ^a   Han, Tae Hee ^a,b   Lee, Kuen Yong ^b   Han, Sung Soo ^c   Hwang, Jung Jin ^a   Moon, Dae Hyuk ^a   Kim, Sang Yoon ^a   Cho, Yong Woo ^a  

^a University of Ulsan College of Medicine   (South Korea)

^b Hanyang University   (South Korea)

^c Yeungnam University   (South Korea)

Author keywords

Cell cycle arrest; Chitosan; Endocytosis; Endosome; Exocytosis; Histidine; Nanoparticle; Paclitaxel

Indexed keywords

AMINES; CONTROLLED DRUG DELIVERY; MEDICAL APPLICATIONS; NANOSTRUCTURED MATERIALS; PH EFFECTS; SELF ASSEMBLY;

CELL CYCLE ARREST; CHITOSAN; ENDOCYTOSIS; ENDOSOMES; EXOCYTOSIS; HISTIDINE; PACLITAXEL;

PROTEINS;

CHITOSAN; GLYCOL; IMIDAZOLE; N ACETYLHISTIDINE; N ACETYLHISTIDINE GLYCOL CHITOSAN CONJUGATE; NANOPARTICLE; PACLITAXEL; UNCLASSIFIED DRUG;

ACIDITY; ADSORPTION; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL CYCLE; CELL CYCLE ARREST; CELL GROWTH; CELL INCLUSION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CULTURE MEDIUM; CYTOSOL; DRUG DELIVERY SYSTEM; DRUG RELEASE; ENDOCYTOSIS; ENDOSOME; EXOCYTOSIS; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HYDROPHILICITY; HYDROPHOBICITY; INTRACELLULAR TRANSPORT; PARTICLE SIZE; PH; PRIORITY JOURNAL; PROTON TRANSPORT;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL CYCLE; CELL LINE, TUMOR; CHITOSAN; DRUG DELIVERY SYSTEMS; ENDOCYTOSIS; EXOCYTOSIS; FLOW CYTOMETRY; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; HISTIDINE; HUMANS; MICROSCOPY, CONFOCAL; NANOSTRUCTURES; PACLITAXEL; PARTICLE SIZE;

EID: 33748785439     PISSN: 01683659     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jconrel.2006.07.011     Document Type: Article

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