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Volumn 9, Issue 12, 1999, Pages 1703-1708

Photoinduced cross-linking of RNA by cis-Rh(phen)2Cl2+ and cis- Rh(phen)(phi)Cl2+: A new family of light activatable nucleic acid cross- linking agents

Author keywords

[No Author keywords available]

Indexed keywords

METAL COMPLEX;

EID: 0033591710     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(99)00265-6     Document Type: Article
Times cited : (26)

References (57)
  • 25
    • 0030884569 scopus 로고    scopus 로고
    • 8. For a recent example of the use of oligonucleotides conjugated to photoactivatable groups to form cross-links to a G on a complementary strand, see: Nakatani, K.; Shirai, J.; Sando, S.; Saito, I. J. Am Chem. Soc. 1997, 119, 7626. While our manuscript was under review, a report has appeared describing DNA cross- linking by a light-activatable progenitor of dehydromonocrotaline which then reacts with the nucleic acid in the dark. This pyrrolizidine alkaloid also targets GC-rich regions of duplex DNA preceding (photo)chemical activation, see: Tepe, J. J.; Williams, R. M. J Am Chem. Soc. 1999, 121, 2951.
    • (1997) J. Am Chem. Soc. , vol.119 , pp. 7626
    • Nakatani, K.1    Shirai, J.2    Sando, S.3    Saito, I.4
  • 26
    • 0033531730 scopus 로고    scopus 로고
    • 8. For a recent example of the use of oligonucleotides conjugated to photoactivatable groups to form cross-links to a G on a complementary strand, see: Nakatani, K.; Shirai, J.; Sando, S.; Saito, I. J. Am Chem. Soc. 1997, 119, 7626. While our manuscript was under review, a report has appeared describing DNA cross- linking by a light-activatable progenitor of dehydromonocrotaline which then reacts with the nucleic acid in the dark. This pyrrolizidine alkaloid also targets GC-rich regions of duplex DNA preceding (photo)chemical activation, see: Tepe, J. J.; Williams, R. M. J Am Chem. Soc. 1999, 121, 2951.
    • (1999) J Am Chem. Soc. , vol.121 , pp. 2951
    • Tepe, J.J.1    Williams, R.M.2
  • 28
    • 0013608166 scopus 로고    scopus 로고
    • Ph. D. Dissertation Purdue University, West Lafayette, IN
    • Terrian, D. L. Ph. D. Dissertation 1996, Purdue University, West Lafayette, IN.
    • (1996)
    • Terrian, D.L.1
  • 34
    • 0013587074 scopus 로고    scopus 로고
    • note
    • 11c
  • 38
    • 0032563227 scopus 로고    scopus 로고
    • (c) Hendrix, R. W. Cell 1998, 94, 147.
    • (1998) Cell , vol.94 , pp. 147
    • Hendrix, R.W.1
  • 40
    • 0013613341 scopus 로고    scopus 로고
    • note
    • 16 The pRNA was purified by 8% polyacrylamide/8 M urea denaturing gel to homogeneity and assayed by UV absorbance at 260 and 280 nm.
  • 43
    • 0013618766 scopus 로고    scopus 로고
    • note
    • The solutions, spotted on prechilled parafilm floating on ice water, were irradiated with a glass-filtered long wavelength UVGL-25 lamp (UVP, Inc.) at a distance of ca. 5 cm.
  • 44
    • 0013604816 scopus 로고    scopus 로고
    • note
    • A Kodak Digital Science DC40 camera in combination with 1D Analysis Software Version 1.6 was used to quantify the bands.
  • 45
    • 0013615824 scopus 로고    scopus 로고
    • note
    • This was confirmed in a time course experiment with 1.0 mM BISPHEN which showed a higher magnitude of pRNA degradation without the production of additional cross-linked pRNA.
  • 48
    • 0013612296 scopus 로고    scopus 로고
    • note
    • 11c,11d
  • 49
    • 0013617426 scopus 로고
    • Ph. D. Dissertation Purdue University, West Lafayette, IN
    • Harmon, H. L. Ph. D. Dissertation 1995, Purdue University, West Lafayette, IN.
    • (1995)
    • Harmon, H.L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.