Involvement of a specific metal ion in the transition of the hammerhead ribozyme to its catalytic conformation

Journal of Biological Chemistry

Volumn 272, Issue 43, 1997, Pages 26822-26826

  Peracchi, Alessio ^a   Beigelman, Leonid ^b   Scott, Edmund C ^c   Uhlenbeck, Olke C ^c   Herschlag, Daniel ^a,d  

^a STANFORD UNIVERSITY   (United States)

^b Sirna Therapeutics Inc   (United States)

^c UNIVERSITY OF COLORADO   (United States)

^d STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CADMIUM; PHOSPHOROTHIOIC ACID DERIVATIVE; RIBOZYME;

ARTICLE; CATALYSIS; CONFORMATIONAL TRANSITION; METAL BINDING; PRIORITY JOURNAL; RNA ANALYSIS; RNA BINDING; RNA CONFORMATION; STRUCTURE ANALYSIS;

BASE SEQUENCE; CADMIUM; CATALYSIS; KINETICS; MAGNESIUM; MODELS, STRUCTURAL; NUCLEIC ACID CONFORMATION; RNA, CATALYTIC; THIONUCLEOTIDES;

EID: 0030876444     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.43.26822     Document Type: Article

References (31)

1. Pley, H. W., Flaherty, K. M., and McKay, D. B. (1994) Nature 372, 68-74
2. Buzayan, J. M., van Tol, H., Feldstein, P. A., and Breuning, G. (1990) Nucleic Acids Res. 18, 4447-4451
3. Ruffner, D, E., and Uhlenbeck, O. C. (1990) Nucleic Acids Res. 18, 6025-6029
4. Ruffner, D. E., Stormo, G. D., and Uhlenbeck, O. C. (1990) Biochemistry 29, 10695-10702
5. Tuschl, T., and Eckstein, F. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 6991-6994
6. Peracchi, A., Beigelman, L., Usman, N., and Herschlag, D. (1996) Proc. Natl. Acad Sci. U. S. A. 93, 11522-11527
7. Scott, W. G., Finch, J. T., and Klug, A. (1995) Cell 81, 991-1002
8. Wincott, F., DiRenzo, A., Shaffer, C., Tracz, D., Workman, C., Sweedler, D., Gonzalez, C., Scaringe, S., and Usman, N. (1995) Nucleic Acids Res. 23, 2677-2684
9. Iyer, R. P., Egan, W., Regan, J. B., and Beaucage, S. L. (1990) J. Am. Chem. Soc. 112, 1253-1254
10. Iyer, R. P., Philips, L. R., Egan, W., Regan, J. B., and Beaucage, S. L. (1990) J. Org. Chem. 55, 4693
11. Slim, G., and Gait, M. J. (1991) Nucleic Acids Res. 19, 1183-1188
12. Burgers, P. M. J., and Eckstein, F. (1978) Proc. Natl. Acad. Sci. U. S. A. 75, 4798-4800
13. Hertel, K. J., Herschlag, D., and Uhlenbeck, O. C. (1994) Biochemistry 33, 3374-3385
14. Clouet-D'Orval, B., and Uhlenbeck, O. C. (1996) RNA (N. Y.) 2, 483-491
15. Dahm, S. C., Derrick, W. B., and Uhlenbeck, O. C. (1993) Biochemistry 32, 13040-13045
16. Jaffe E. K., and Cohn, M. (1978) J. Biol. Chem. 253, 4823-4825
17. Pecoraro, V. L., Hermes, J. D., and Cleland, W. W. (1984) Biochemistry 23, 5262-5271
18. Sigel, R. K. O., and Sigel, H. (1997) J. Am. Chem. Soc. 119, 744-755
19. Eckstein, F. (1985) Annu. Rev. Biochem. 54, 367-402
20. Dahm, S. C., and Uhlenbeck, O. C. (1991) Biochemistry 30, 9464-9469
21. Pabon-Pena, L. M., Zhang, Y., and Epstein, L. M. (1991) Mol. Cell. Biol. 11, 6109-6115
22. Piccirilli, J. A., Vyle, J. S., Caruthers, M. H., and Cech, T. R. (1993) Nature 361, 85-88
23. Warnecke, J. M., Furste, J. P., Hardt, W.-D., Erdmann, V. A., and Hartman, R. K. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 8924-8928
24. Weinstein, L. B., Jones, B. C. N. M., Cosstick, R., and Cech, T. R. (1997) Nature, in press
25. Knoll, R., Bald, R., and Furste, J. P. (1997) RNA (N. Y.) 3, 132-140
26. Ruffner, D. E., Dahm, S. A., and Uhlenbeck, O. C. (1989) Gene (Amst.) 82, 31-41
27. Kragten, J. (1978) Atlas of Metal-Ligand Equilibria in Aqueous Solution, John Wiley & Sons, New York
28. McKay, D. B. (1996) RNA (N. Y.) 2, 395-403
29. Sillen, L. G., and Martell, A. E. (1964) Stability Constants of Metal-Ion Complexes, Burlington House, London
30. Scott, W. G., Murray, J. B., Arnold, J. R. P., Stoddard, B. L., and Klug, A. (1996) Science 274, 2065-2069
31. Hertel, K. J., Pardi, A., Uhlenbeck, O. C., Koizumi, M., Ohtsuka, E., Uesugi, S., Cedergren, R., Eckstein, F., Gerlach, W., Hodgson, R., and Symons, R. H. (1992) Nucleic Acids Res. 20, 3252