Conformational freedom in tight binding enzymatic transition-state analogues

Journal of Physical Chemistry B

Volumn 117, Issue 33, 2013, Pages 9591-9597

  Motley, Matthew W ^b   Schramm, Vern L ^b   Schwartz, Steven D ^a  

^a University of Arizona   (United States)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC RESISTANCE; CONFORMATIONAL FREEDOM; HYDROPHOBIC INTERACTIONS; MOLECULAR DYNAMICS SIMULATIONS; PROTEIN DYNAMICS; SELECTIVE PRESSURE; TRANSITION STATE; TRANSITION-STATE ANALOGUES;

ESCHERICHIA COLI; MOLECULAR DYNAMICS;

PROTEINS;

5' METHYLTHIOADENOSINE NUCLEOSIDASE, E COLI; 5'-METHYLTHIOADENOSINE NUCLEOSIDASE, E COLI; ADENINE; BACTERIAL PROTEIN; DRUG DERIVATIVE; ESCHERICHIA COLI PROTEIN; GLYCOSIDASE; IMMUCILLIN A; PYRROLIDINE DERIVATIVE;

ARTICLE; BACTERIUM; BINDING SITE; CHEMICAL PHENOMENA; CHEMISTRY; ENZYME ACTIVE SITE; ENZYMOLOGY; ESCHERICHIA COLI; HYDROGEN BOND; METABOLISM; MOLECULAR DYNAMICS; PROTEIN BINDING; VIBRIO CHOLERAE;

ADENINE; BACTERIA; BACTERIAL PROTEINS; BINDING SITES; CATALYTIC DOMAIN; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; HYDROGEN BONDING; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MOLECULAR DYNAMICS SIMULATION; N-GLYCOSYL HYDROLASES; PROTEIN BINDING; PYRROLIDINES; VIBRIO CHOLERAE;

EID: 84883190758     PISSN: 15206106     EISSN: 15205207     Source Type: Journal    
DOI: 10.1021/jp4030443     Document Type: Article

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