Promoting vibrations in human purine nucleoside phosphorylase. A molecular dynamics and hybrid quantum mechanical/molecular mechanical study

Journal of the American Chemical Society

Volumn 126, Issue 48, 2004, Pages 15720-15729

  Núñez, Sara ^a   Antoniou, Dimitri ^a   Schramm, Vern L ^a   Schwartz, Steven D ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER CONCENTRATION; CATALYSIS; CHEMICAL BONDS; COMPUTER SIMULATION; CRYSTALLOGRAPHY; ELECTROSTATICS; ISOTOPES; MOLECULAR DYNAMICS; MOLECULAR VIBRATIONS; OXYGEN; QUANTUM THEORY;

IMMUCILLIN; KINETIC ISOTOPE EFFECTS; PROTEIN-PROMOTING VIBRATIONS (PPV); TRANSITION-STATE (TS) ANALOGUES;

ENZYMES;

PHOSPHORYLASE; PURINE NUCLEOSIDE;

ARTICLE; ATOMIC PARTICLE; CHEMICAL REACTION; CRYSTALLOGRAPHY; ELECTRICITY; ENERGY TRANSFER; ENZYME ANALYSIS; GEOMETRY; KINETICS; MICHAELIS CONSTANT; MOLECULAR DYNAMICS; QUANTUM CHEMISTRY; VIBRATION;

EID: 10044273966     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja0457563     Document Type: Article

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