A picomolar transition state analogue inhibitor of MTAN as a specific antibiotic for helicobacter pylori

Biochemistry

Volumn 51, Issue 35, 2012, Pages 6892-6894

  Wang, Shanzhi ^a   Haapalainen, Antti M ^a   Yan, Funing ^a   Du, Quan ^a   Tyler, Peter C ^b   Evans, Gary B ^b   Rinaldo Matthis, Agnes ^a   Brown, Rosemary L ^c   Norris, Gillian E ^c   Almo, Steven C ^a   Schramm, Vern L ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b CALLAGHAN INNOVATION   (New Zealand)

^c MASSEY UNIVERSITY   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

CAMPYLOBACTERS; ENZYME-INHIBITOR COMPLEX; GROWTH ARREST; HELICOBACTER; HELICOBACTER PYLORI; TRANSITION-STATE ANALOGUES;

ANTIBIOTICS;

ENZYME INHIBITION;

5' METHYLTHIOADENOSINE; AMOXICILLIN; ANTIBIOTIC AGENT; BUT DADME IMMA; MENAQUINONE; METRONIDAZOLE; TETRACYCLINE; UNCLASSIFIED DRUG;

ANTIBIOTIC THERAPY; ANTIMICROBIAL ACTIVITY; ARTICLE; BACTERIAL GROWTH; CONTROLLED STUDY; CRYSTAL STRUCTURE; DRUG SYNTHESIS; HELICOBACTER INFECTION; HELICOBACTER PYLORI; NONHUMAN; PRIORITY JOURNAL;

ADENINE; ANTI-BACTERIAL AGENTS; ENZYME INHIBITORS; HELICOBACTER INFECTIONS; HELICOBACTER PYLORI; HUMANS; MODELS, MOLECULAR; N-GLYCOSYL HYDROLASES; PYRROLIDINES;

CAMPYLOBACTER; HELICOBACTER; HELICOBACTER PYLORI;

EID: 84865709239     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi3009664     Document Type: Article

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