Picomolar Transition State Analogue Inhibitors of Human 5′-Methylthioadenosine Phosphorylase and X-ray Structure with MT-Immucillin-A

Biochemistry

Volumn 43, Issue 1, 2004, Pages 9-18

  Singh, Vipender ^a   Shi, Wuxian ^a   Evans, Gary B ^b   Tyler, Peter C ^b   Furneaux, Richard H ^b   Almo, Steven C ^a   Schramm, Vern L ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b CALLAGHAN INNOVATION   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

AMINES; DISSOCIATION; ENZYMES; HYDROPHOBICITY; NEGATIVE IONS; PHOSPHATES; RNA; SYNTHESIS (CHEMICAL); X RAYS;

ION PAIRS;

BIOCHEMISTRY;

5' METHYLTHIOADENOSINE PHOSPHORYLASE; ADENOSINE DERIVATIVE; ENZYME INHIBITOR; METHYLTHIOIMMUCILLIN A; POLYAMINE; SPERMIDINE; SPERMIDINE SYNTHASE; SPERMINE; SPERMINE SYNTHASE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BIOSYNTHESIS; CATALYSIS; CRYSTAL STRUCTURE; DRUG TARGETING; ENZYME INHIBITION; ENZYME STRUCTURE; ESCHERICHIA COLI; HUMAN; HYDROPHOBICITY; NONHUMAN; POLYAMINE SYNTHESIS; PRIORITY JOURNAL;

ESCHERICHIA COLI; MAMMALIA;

EID: 0346096864     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0358420     Document Type: Article

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