Role of hypoxia-inducible factor 1, a subunit and cAMP-response element binding protein 1 in synergistic release of interleukin 8 by prostaglandin E2 and nickel in lung fibroblasts

American Journal of Respiratory Cell and Molecular Biology

Volumn 49, Issue 1, 2013, Pages 105-113

  Brant, Kelly A ^a   Fabisiak, James P ^a  

^a UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Fibroblast; HIF1A; IL 8; Nickel; Prostaglandin E2

Indexed keywords

6 ISOPROPOXY 9 OXO 2 XANTHENECARBOXYLIC ACID; ACTIVATING TRANSCRIPTION FACTOR 2; ALCOHOL; BINDING PROTEIN; BUTAPROST; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT BINDING PROTEIN 1; FORSKOLIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; INTERLEUKIN 8; L 161 982; MITOGEN ACTIVATED PROTEIN KINASE P38; NICKEL; PROSTAGLANDIN E RECEPTOR 2; PROSTAGLANDIN E RECEPTOR 4; PROSTAGLANDIN E1; PROSTAGLANDIN E2; PROSTAGLANDIN RECEPTOR BLOCKING AGENT; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

AIR POLLUTION; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHEMICAL INTERACTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOKINE RESPONSE; ENZYME ACTIVATION; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; IMMUNOMODULATION; LUNG FIBROBLAST; LUNG TOXICITY; MOLECULAR MECHANICS; PARTICULATE MATTER; PROTEIN DNA BINDING; PROTEIN FUNCTION; PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ALPROSTADIL; BIOMIMETICS; CELLS, CULTURED; CYCLIC AMP; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DINOPROSTONE; DRUG SYNERGISM; FIBROBLASTS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; INFLAMMATION; INTERLEUKIN-8; LUNG; NICKEL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; RECEPTORS, PROSTAGLANDIN E; RECEPTORS, PROSTAGLANDIN E, EP2 SUBTYPE; RECEPTORS, PROSTAGLANDIN E, EP4 SUBTYPE; SIGNAL TRANSDUCTION; XANTHONES;

EID: 84883146421     PISSN: 10441549     EISSN: 15354989     Source Type: Journal    
DOI: 10.1165/rcmb.2012-0297OC     Document Type: Article

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