메뉴 건너뛰기




Volumn 16, Issue 8, 2013, Pages 681-691

Antrodia camphorata grown on germinated brown rice inhibits HT-29 human colon carcinoma proliferation through inducing G0/G1 phase arrest and apoptosis by targeting the β-catenin signaling

Author keywords

Antrodia camphorata grown on germinated brown rice (CBR); apoptosis; b catenin; colon cancer; G0 G1 cell cycle arrest

Indexed keywords

ACETIC ACID ETHYL ESTER; ANTINEOPLASTIC AGENT; ANTRODIA CAMPHORATA EXTRACT; BETA CATENIN; BUTANOL; CYCLIN D1; CYCLIN DEPENDENT KINASE 4; HEXANE; LIPOCORTIN 5; PLANT EXTRACT; UNCLASSIFIED DRUG; WATER;

EID: 84883000230     PISSN: 1096620X     EISSN: 15577600     Source Type: Journal    
DOI: 10.1089/jmf.2012.2605     Document Type: Article
Times cited : (10)

References (55)
  • 4
    • 0032008099 scopus 로고    scopus 로고
    • Novel therapeutic strategies to selectively kill cancer cells
    • Panchal RG: Novel therapeutic strategies to selectively kill cancer cells. Biochem Pharmacol 1998;55:247-252.
    • (1998) Biochem Pharmacol , vol.55 , pp. 247-252
    • Panchal, R.G.1
  • 5
    • 17144464406 scopus 로고    scopus 로고
    • Aberrant crypt foci of the colon as precursors of adenoma and cancer
    • Takayama T, Katsuki S, Takahashi Y, et al.: Aberrant crypt foci of the colon as precursors of adenoma and cancer. N Engl J Med 1998;339:1277-1284.
    • (1998) N Engl J Med , vol.339 , pp. 1277-1284
    • Takayama, T.1    Katsuki, S.2    Takahashi, Y.3
  • 6
    • 33845373278 scopus 로고    scopus 로고
    • Colorectal cancer and genetic alterations in the Wnt pathway
    • Segditsas S, Tomlinson I: Colorectal cancer and genetic alterations in the Wnt pathway. Oncogene 2006;25:7531-7537.
    • (2006) Oncogene , vol.25 , pp. 7531-7537
    • Segditsas, S.1    Tomlinson, I.2
  • 7
    • 84863297208 scopus 로고    scopus 로고
    • Antrodia camphorata induces apoptosis and enhances the cytotoxic effect of paclitaxel in human ovarian cancer cells
    • Liu FS, Yang PY, Hu DN, Huang YW, Chen MJ: Antrodia camphorata induces apoptosis and enhances the cytotoxic effect of paclitaxel in human ovarian cancer cells. Int J Gynecol Cancer 2011;21:1172-1179.
    • (2011) Int J Gynecol Cancer , vol.21 , pp. 1172-1179
    • Liu, F.S.1    Yang, P.Y.2    Hu, D.N.3    Huang, Y.W.4    Chen, M.J.5
  • 8
    • 0035964349 scopus 로고    scopus 로고
    • Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment
    • Brabletz T, Jung A, Reu S, et al.: Variable beta-catenin expression in colorectal cancers indicates tumor progression driven by the tumor environment. Proc Natl Acad Sci USA 2001;98: 10356-10361.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 10356-10361
    • Brabletz, T.1    Jung, A.2    Reu, S.3
  • 9
    • 1642405321 scopus 로고    scopus 로고
    • Prognostic and diagnostic significance of beta-catenin nuclear immunostaining in colorectal cancer
    • Wong SC, Lo ES, Lee KC, Chan JK, Hsiao WL: Prognostic and diagnostic significance of beta-catenin nuclear immunostaining in colorectal cancer. Clin Cancer Res 2004;10:1401-1408.
    • (2004) Clin Cancer Res , vol.10 , pp. 1401-1408
    • Wong, S.C.1    Lo, E.S.2    Lee, K.C.3    Chan, J.K.4    Hsiao, W.L.5
  • 10
    • 34848852249 scopus 로고    scopus 로고
    • Effect of methanolic extract from silkworm droppings on proliferation and caspase activity in HT-29 human colon cancer cells
    • Hwang JH, Kim JY, Cha MR, Park HR: Effect of methanolic extract from silkworm droppings on proliferation and caspase activity in HT-29 human colon cancer cells. J Med Food 2007;10:467-472.
    • (2007) J Med Food , vol.10 , pp. 467-472
    • Hwang, J.H.1    Kim, J.Y.2    Cha, M.R.3    Park, H.R.4
  • 11
    • 57949110602 scopus 로고    scopus 로고
    • Niuchangchih (Antrodia camphorata) and its potential in treating liver diseases
    • Ao ZH, Xu ZH, Lu ZM, Xu HY, Zhang XM, Dou WF: Niuchangchih (Antrodia camphorata) and its potential in treating liver diseases. J Ethnopharmacol 2009;121:194-212.
    • (2009) J Ethnopharmacol , vol.121 , pp. 194-212
    • Ao, Z.H.1    Xu, Z.H.2    Lu, Z.M.3    Xu, H.Y.4    Zhang, X.M.5    Dou, W.F.6
  • 12
    • 34249888778 scopus 로고    scopus 로고
    • Unique formosan mushroom Antrodia camphorata differentially inhibits androgenresponsive LNCaP and -independent PC-3 prostate cancer cells
    • Chen KC, Peng CC, Peng RY, et al.: Unique formosan mushroom Antrodia camphorata differentially inhibits androgenresponsive LNCaP and -independent PC-3 prostate cancer cells. Nutr Cancer 2007;57:111-121.
    • (2007) Nutr Cancer , vol.57 , pp. 111-121
    • Chen, K.C.1    Peng, C.C.2    Peng, R.Y.3
  • 13
    • 79955104715 scopus 로고    scopus 로고
    • A preclinical evaluation of Antrodia camphorata alcohol extracts in the treatment of nonsmall cell lung cancer using non-invasive molecular imaging
    • Chiou JF, Wu AT, Wang WT, et al.: A preclinical evaluation of Antrodia camphorata alcohol extracts in the treatment of nonsmall cell lung cancer using non-invasive molecular imaging. Evid Based Complement Alternat Med 2011;2011:914561.
    • (2011) Evid Based Complement Alternat Med , vol.2011 , pp. 914561
    • Chiou, J.F.1    Wu, A.T.2    Wang, W.T.3
  • 14
    • 80255131246 scopus 로고    scopus 로고
    • Chemical profiling of the cytotoxic triterpenoid-concentrating fraction and characterization of ergostane stereo-isomer ingredients from Antrodia camphorata
    • Du YC, Wu TY, Chang FR, et al.: Chemical profiling of the cytotoxic triterpenoid-concentrating fraction and characterization of ergostane stereo-isomer ingredients from Antrodia camphorata. J Pharm Biomed Anal 2012;58:182-192.
    • (2012) J Pharm Biomed Anal , vol.58 , pp. 182-192
    • Du, Y.C.1    Wu, T.Y.2    Chang, F.R.3
  • 15
    • 79952231175 scopus 로고    scopus 로고
    • Review of pharmacological effects of Antrodia camphorata and its bioactive compounds
    • Geethangili M, Tzeng YM: Review of pharmacological effects of Antrodia camphorata and its bioactive compounds. Evid Based Complement Alternat Med 2011;2011:212641.
    • (2011) Evid Based Complement Alternat Med , vol.2011 , pp. 212641
    • Geethangili, M.1    Tzeng, Y.M.2
  • 16
    • 51049087483 scopus 로고    scopus 로고
    • Effects of Antrodia camphorata on viability, apoptosis, and [Ca2 + ]i in PC3 human prostate cancer cells
    • Ho CM, Huang CC, Huang CJ, et al.: Effects of Antrodia camphorata on viability, apoptosis, and [Ca2 + ]i in PC3 human prostate cancer cells. Chin J Physiol 2008;51:78-84.
    • (2008) Chin J Physiol , vol.51 , pp. 78-84
    • Ho, C.M.1    Huang, C.C.2    Huang, C.J.3
  • 17
    • 0037077024 scopus 로고    scopus 로고
    • Protection of oxidative damage by aqueous extract from Antrodia camphorata mycelia in normal human erythrocytes
    • Hseu YC, Chang WC, Hseu YT, et al.: Protection of oxidative damage by aqueous extract from Antrodia camphorata mycelia in normal human erythrocytes. Life Sci 2002;71:469-482.
    • (2002) Life Sci , vol.71 , pp. 469-482
    • Hseu, Y.C.1    Chang, W.C.2    Hseu, Y.T.3
  • 18
    • 47149101600 scopus 로고    scopus 로고
    • Antrodia camphorata inhibits proliferation of human breast cancer cells in vitro and in vivo
    • Hseu YC, Chen SC, Chen HC, Liao JW, Yang HL: Antrodia camphorata inhibits proliferation of human breast cancer cells in vitro and in vivo. Food Chem Toxicol 2008;46:2680-2688.
    • (2008) Food Chem Toxicol , vol.46 , pp. 2680-2688
    • Hseu, Y.C.1    Chen, S.C.2    Chen, H.C.3    Liao, J.W.4    Yang, H.L.5
  • 19
    • 34247140126 scopus 로고    scopus 로고
    • Inhibition of cyclooxygenase-2 and induction of apoptosis in estrogen-nonresponsive breast cancer cells by Antrodia camphorata
    • Hseu YC, Chen SC, Tsai PC, et al.: Inhibition of cyclooxygenase-2 and induction of apoptosis in estrogen-nonresponsive breast cancer cells by Antrodia camphorata. Food Chem Toxicol 2007;45:1107-1115.
    • (2007) Food Chem Toxicol , vol.45 , pp. 1107-1115
    • Hseu, Y.C.1    Chen, S.C.2    Tsai, P.C.3
  • 20
    • 3843084006 scopus 로고    scopus 로고
    • Induction of apoptosis by Antrodia camphorata in human premyelocytic leukemia HL-60 cells
    • Hseu YC, Yang HL, Lai YC, Lin JG, Chen GW, Chang YH: Induction of apoptosis by Antrodia camphorata in human premyelocytic leukemia HL-60 cells. Nutr Cancer 2004;48: 189-197.
    • (2004) Nutr Cancer , vol.48 , pp. 189-197
    • Hseu, Y.C.1    Yang, H.L.2    Lai, Y.C.3    Lin, J.G.4    Chen, G.W.5    Chang, Y.H.6
  • 21
    • 77955369919 scopus 로고    scopus 로고
    • Methyl antcinate A from Antrodia camphorata induces apoptosis in human liver cancer cells through oxidant-mediated cofilin- and Bax-triggered mitochondrial pathway
    • Hsieh YC, Rao YK, Wu CC, et al.: Methyl antcinate A from Antrodia camphorata induces apoptosis in human liver cancer cells through oxidant-mediated cofilin- and Bax-triggered mitochondrial pathway. Chem Res Toxicol 2010;23:1256-1267.
    • (2010) Chem Res Toxicol , vol.23 , pp. 1256-1267
    • Hsieh, Y.C.1    Rao, Y.K.2    Wu, C.C.3
  • 22
    • 70349405948 scopus 로고    scopus 로고
    • Effects of Antrodia camphorata extracts on the viability, apoptosis, [Ca2 + ] i, and MAPKs phosphorylation of OC2 human oral cancer cells
    • Huang CC, Cheng HH, Wang JL, et al.: Effects of Antrodia camphorata extracts on the viability, apoptosis, [Ca2 + ]i, and MAPKs phosphorylation of OC2 human oral cancer cells. Chin J Physiol 2009;52:128-135.
    • (2009) Chin J Physiol , vol.52 , pp. 128-135
    • Huang, C.C.1    Cheng, H.H.2    Wang, J.L.3
  • 23
    • 13844322509 scopus 로고    scopus 로고
    • Antrodia camphorata prevents rat pheochromocytoma cells from serum deprivationinduced apoptosis
    • Huang NK, Cheng JJ, Lai WL, Lu MK: Antrodia camphorata prevents rat pheochromocytoma cells from serum deprivationinduced apoptosis. FEMS Microbiol Lett 2005;244:213-219.
    • (2005) FEMS Microbiol Lett , vol.244 , pp. 213-219
    • Huang, N.K.1    Cheng, J.J.2    Lai, W.L.3    Lu, M.K.4
  • 24
    • 69049116370 scopus 로고    scopus 로고
    • The augmented anti-tumor effects of Antrodia camphorata co-fermented with Chinese medicinal herb in human hepatoma cells
    • Li SL, Huang ZN, Hsieh HH, et al.: The augmented anti-tumor effects of Antrodia camphorata co-fermented with Chinese medicinal herb in human hepatoma cells. Am J Chin Med 2009;37:771-783.
    • (2009) Am J Chin Med , vol.37 , pp. 771-783
    • Li, S.L.1    Huang, Z.N.2    Hsieh, H.H.3
  • 25
    • 79959284120 scopus 로고    scopus 로고
    • Study of the anti-proliferative activity of 5-substituted 4,7-dimethoxy-1,3-benzodioxole derivatives of SY-1 from Antrodia camphorata on human COLO 205 colon cancer cells
    • Lien HM, Kuo PT, Huang CL, et al.: Study of the anti-proliferative activity of 5-substituted 4,7-dimethoxy-1,3-benzodioxole derivatives of SY-1 from Antrodia camphorata on human COLO 205 colon cancer cells. Evid Based Complement Alternat Med 2011;2011:450529.
    • (2011) Evid Based Complement Alternat Med , vol.2011 , pp. 450529
    • Lien, H.M.1    Kuo, P.T.2    Huang, C.L.3
  • 26
    • 77953986326 scopus 로고    scopus 로고
    • Dietary effect of Antrodia camphorate extracts on immune responses in WEHI-3 leukemia BALB/c mice
    • Lin SY, Sheen LY, Chiang BH, et al.: Dietary effect of Antrodia camphorate extracts on immune responses in WEHI-3 leukemia BALB/c mice. Nutr Cancer 2010;62:593-600.
    • (2010) Nutr Cancer , vol.62 , pp. 593-600
    • Lin, S.Y.1    Sheen, L.Y.2    Chiang, B.H.3
  • 27
    • 8444250984 scopus 로고    scopus 로고
    • Antitumor effects of the partially purified polysaccharides from Antrodia camphorata and the mechanism of its action
    • Liu JJ, Huang TS, Hsu ML, et al.: Antitumor effects of the partially purified polysaccharides from Antrodia camphorata and the mechanism of its action. Toxicol Appl Pharmacol 2004; 201:186-193.
    • (2004) Toxicol Appl Pharmacol , vol.201 , pp. 186-193
    • Liu, J.J.1    Huang, T.S.2    Hsu, M.L.3
  • 28
    • 60449104605 scopus 로고    scopus 로고
    • Active extracts of wild fruiting bodies of Antrodia camphorata (EEAC) induce leukemia HL 60 cells apoptosis partially through histone hypoacetylation and synergistically promote anticancer effect of trichostatin A
    • Lu MC, Du YC, Chuu JJ, et al.: Active extracts of wild fruiting bodies of Antrodia camphorata (EEAC) induce leukemia HL 60 cells apoptosis partially through histone hypoacetylation and synergistically promote anticancer effect of trichostatin A. Arch Toxicol 2009;83:121-129.
    • (2009) Arch Toxicol , vol.83 , pp. 121-129
    • Lu, M.C.1    Du, Y.C.2    Chuu, J.J.3
  • 29
    • 79951846076 scopus 로고    scopus 로고
    • Identification of antrocin from Antrodia camphorata as a selective and novel class of small molecule inhibitor of Akt/mTOR signaling in metastatic breast cancer MDA-MB-231 cells
    • Rao YK, Wu AT, Geethangili M, et al.: Identification of antrocin from Antrodia camphorata as a selective and novel class of small molecule inhibitor of Akt/mTOR signaling in metastatic breast cancer MDA-MB-231 cells. Chem Res Toxicol 2011;24: 238-245.
    • (2011) Chem Res Toxicol , vol.24 , pp. 238-245
    • Rao, Y.K.1    Wu, A.T.2    Geethangili, M.3
  • 30
    • 77956913103 scopus 로고    scopus 로고
    • Methylantcinate A induces tumor specific growth inhibition in oral cancer cells via Baxmediated mitochondrial apoptotic pathway
    • Tsai WC, Rao YK, Lin SS, et al.: Methylantcinate A induces tumor specific growth inhibition in oral cancer cells via Baxmediated mitochondrial apoptotic pathway. Bioorg Med Chem Lett 2010;20:6145-6148.
    • (2010) Bioorg Med Chem Lett , vol.20 , pp. 6145-6148
    • Tsai, W.C.1    Rao, Y.K.2    Lin, S.S.3
  • 31
    • 77954526401 scopus 로고    scopus 로고
    • The ethyl acetate extract of Phellinus linteus grown on germinated brown rice induces G(0)/G(1) cell cycle arrest and apoptosis in human colon carcinoma HT29 cells
    • Park HJ, Choi SY, Hong SM, Hwang SG, Park DK: The ethyl acetate extract of Phellinus linteus grown on germinated brown rice induces G(0)/G(1) cell cycle arrest and apoptosis in human colon carcinoma HT29 cells. Phytother Res 24:1019-1026.
    • Phytother Res , vol.24 , pp. 1019-1026
    • Park, H.J.1    Choi, S.Y.2    Hong, S.M.3    Hwang, S.G.4    Park, D.K.5
  • 32
    • 79955692137 scopus 로고    scopus 로고
    • The ethyl acetate extract of Cordyceps militaris inhibits IgE-mediated allergic responses in mast cells and passive cutaneous anaphylaxis reaction in mice
    • Oh JY, Choi WS, Lee CH, Park HJ: The ethyl acetate extract of Cordyceps militaris inhibits IgE-mediated allergic responses in mast cells and passive cutaneous anaphylaxis reaction in mice. J Ethnopharmacol 2011;135:422-429.
    • (2011) J Ethnopharmacol , vol.135 , pp. 422-429
    • Oh, J.Y.1    Choi, W.S.2    Lee, C.H.3    Park, H.J.4
  • 33
    • 79954415898 scopus 로고    scopus 로고
    • Cordyceps militaris extract suppresses dextran sodium sulfate-induced acute colitis in mice and production of inflammatory mediators from macrophages and mast cells
    • Han ES, Oh JY, Park HJ: Cordyceps militaris extract suppresses dextran sodium sulfate-induced acute colitis in mice and production of inflammatory mediators from macrophages and mast cells. J Ethnopharmacol 2011;134:703-710.
    • (2011) J Ethnopharmacol , vol.134 , pp. 703-710
    • Han, E.S.1    Oh, J.Y.2    Park, H.J.3
  • 34
    • 0029118035 scopus 로고
    • Cell cycle-dependent phosphorylation of the retinoblastoma-related protein p130
    • Mayol X, Garriga J, Grana X: Cell cycle-dependent phosphorylation of the retinoblastoma-related protein p130. Oncogene 1995;11:801-808.
    • (1995) Oncogene , vol.11 , pp. 801-808
    • Mayol, X.1    Garriga, J.2    Grana, X.3
  • 35
    • 35648964224 scopus 로고    scopus 로고
    • Cyclin degradation for cancer therapy and chemoprevention
    • Freemantle SJ, Liu X, Feng Q, et al.: Cyclin degradation for cancer therapy and chemoprevention. J Cell Biochem 2007;102: 869-877.
    • (2007) J Cell Biochem , vol.102 , pp. 869-877
    • Freemantle, S.J.1    Liu, X.2    Feng, Q.3
  • 36
    • 33845298932 scopus 로고    scopus 로고
    • Modulation of the cell cycle and induction of apoptosis in human cancer cells by synthetic bile acids
    • Kim ND, Im E, Yoo YH, Choi YH: Modulation of the cell cycle and induction of apoptosis in human cancer cells by synthetic bile acids. Current Cancer Drug Targets 2006;6:681-689.
    • (2006) Current Cancer Drug Targets , vol.6 , pp. 681-689
    • Kim, N.D.1    Im, E.2    Yoo, Y.H.3    Choi, Y.H.4
  • 37
    • 4344587136 scopus 로고    scopus 로고
    • A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]
    • Emami KH, Nguyen C, Ma H, et al.: A small molecule inhibitor of beta-catenin/CREB-binding protein transcription [corrected]. Proc Natl Acad Sci USA 2004;101:12682-12687.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 12682-12687
    • Emami, K.H.1    Nguyen, C.2    Ma, H.3
  • 38
    • 0033119801 scopus 로고    scopus 로고
    • Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • Tetsu O, McCormick F: Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999;398:422-426.
    • (1999) Nature , vol.398 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 39
    • 79952025254 scopus 로고    scopus 로고
    • Ganodermanontriol, a lanostanoid triterpene from Ganoderma lucidum, suppresses growth of colon cancer cells through ss-catenin signaling
    • Jedinak A, Thyagarajan-Sahu A, Jiang J, Sliva D: Ganodermanontriol, a lanostanoid triterpene from Ganoderma lucidum, suppresses growth of colon cancer cells through ss-catenin signaling. Int J Oncol 2011;38:761-767.
    • (2011) Int J Oncol , vol.38 , pp. 761-767
    • Jedinak, A.1    Thyagarajan-Sahu, A.2    Jiang, J.3    Sliva, D.4
  • 41
    • 0028910191 scopus 로고
    • P53 derived from human tumour cell lines and containing distinct point mutations can be activated to bind its consensus target sequence
    • Niewolik D, Vojtesek B, Kovarik J: P53 derived from human tumour cell lines and containing distinct point mutations can be activated to bind its consensus target sequence. Oncogene 1995;10:881-890.
    • (1995) Oncogene , vol.10 , pp. 881-890
    • Niewolik, D.1    Vojtesek, B.2    Kovarik, J.3
  • 42
    • 84855428523 scopus 로고    scopus 로고
    • Morphogenesis and the cell cycle
    • Howell AS, Lew DJ: Morphogenesis and the cell cycle. Genetics 2012;190:51-77.
    • (2012) Genetics , vol.190 , pp. 51-77
    • Howell, A.S.1    Lew, D.J.2
  • 43
    • 0036765673 scopus 로고    scopus 로고
    • Antitumor activity of palmitic acid found as a selective cytotoxic substance in a marine red alga
    • Harada H, Yamashita U, Kurihara H, Fukushi E, Kawabata J, Kamei Y: Antitumor activity of palmitic acid found as a selective cytotoxic substance in a marine red alga. Anticancer Res 2002;22:2587-2590.
    • (2002) Anticancer Res , vol.22 , pp. 2587-2590
    • Harada, H.1    Yamashita, U.2    Kurihara, H.3    Fukushi, E.4    Kawabata, J.5    Kamei, Y.6
  • 44
    • 0028129951 scopus 로고
    • The PRAD-1/cyclin D1 oncogene product accumulates aberrantly in a subset of colorectal carcinomas
    • Bartkova J, Lukas J, Strauss M, Bartek J: The PRAD-1/cyclin D1 oncogene product accumulates aberrantly in a subset of colorectal carcinomas. Int J Cancer 1994;58:568-573.
    • (1994) Int J Cancer , vol.58 , pp. 568-573
    • Bartkova, J.1    Lukas, J.2    Strauss, M.3    Bartek, J.4
  • 45
    • 0031438751 scopus 로고    scopus 로고
    • Transforming growth factor-alpha enhances cyclin D1 transcription through the binding of early growth response protein to a cis-regulatory element in the cyclin D1 promoter
    • Yan YX, Nakagawa H, Lee MH, Rustgi AK: Transforming growth factor-alpha enhances cyclin D1 transcription through the binding of early growth response protein to a cis-regulatory element in the cyclin D1 promoter. J Biol Chem 1997;272: 33181-33190.
    • (1997) J Biol Chem , vol.272 , pp. 33181-33190
    • Yan, Y.X.1    Nakagawa, H.2    Lee, M.H.3    Rustgi, A.K.4
  • 46
    • 0036581949 scopus 로고    scopus 로고
    • Phytochemicals as cell cycle modulators-a less toxic approach in halting human cancers
    • Singh RP, Dhanalakshmi S, Agarwal R: Phytochemicals as cell cycle modulators-a less toxic approach in halting human cancers. Cell Cycle 2002;1:156-161.
    • (2002) Cell Cycle , vol.1 , pp. 156-161
    • Singh, R.P.1    Dhanalakshmi, S.2    Agarwal, R.3
  • 47
    • 67649965950 scopus 로고    scopus 로고
    • The mitochondrial death pathway: A promising therapeutic target in diseases
    • Gupta S, Kass GE, Szegezdi E, Joseph B: The mitochondrial death pathway: A promising therapeutic target in diseases. J Cell Mol Med 2009;13:1004-1033.
    • (2009) J Cell Mol Med , vol.13 , pp. 1004-1033
    • Gupta, S.1    Kass, G.E.2    Szegezdi, E.3    Joseph, B.4
  • 49
    • 60149112516 scopus 로고    scopus 로고
    • A plant flavonoid fisetin induces apoptosis in colon cancer cells by inhibition of COX2 and Wnt/EGFR/NF-kappaB-signaling pathways
    • Suh Y, Afaq F, Johnson JJ, Mukhtar H: A plant flavonoid fisetin induces apoptosis in colon cancer cells by inhibition of COX2 and Wnt/EGFR/NF-kappaB- signaling pathways. Carcinogenesis 2009;30:300-307.
    • (2009) Carcinogenesis , vol.30 , pp. 300-307
    • Suh, Y.1    Afaq, F.2    Johnson, J.J.3    Mukhtar, H.4
  • 50
    • 0027960448 scopus 로고
    • Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation
    • Stambolic V, Woodgett JR: Mitogen inactivation of glycogen synthase kinase-3 beta in intact cells via serine 9 phosphorylation. Biochem J 1994;303:701-704.
    • (1994) Biochem J , vol.303 , pp. 701-704
    • Stambolic, V.1    Woodgett, J.R.2
  • 51
    • 18344389705 scopus 로고    scopus 로고
    • Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling
    • Palmer HG, Gonzalez-Sancho JM, Espada J, et al.: Vitamin D(3) promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of beta-catenin signaling. J Cell Biol 2001;154:369-387.
    • (2001) J Cell Biol , vol.154 , pp. 369-387
    • Palmer, H.G.1    Gonzalez-Sancho, J.M.2    Espada, J.3
  • 52
    • 0032510494 scopus 로고    scopus 로고
    • A causal role for E-cadherin in the transition from adenoma to carcinoma
    • Perl AK, Wilgenbus P, Dahl U, Semb H, Christofori G: A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature 1998;392:190-193.
    • (1998) Nature , vol.392 , pp. 190-193
    • Perl, A.K.1    Wilgenbus, P.2    Dahl, U.3    Semb, H.4    Christofori, G.5
  • 53
    • 0034042381 scopus 로고    scopus 로고
    • Suppression of breast cancer invasion and migration by indole-3-carbinol: Associated with upregulation of BRCA1 and E-cadherin/catenin complexes
    • Meng Q, Qi M, Chen DZ, et al.: Suppression of breast cancer invasion and migration by indole-3-carbinol: Associated with upregulation of BRCA1 and E-cadherin/catenin complexes. J Mol Med (Berl) 2000;78:155-165.
    • (2000) J Mol Med (Berl) , vol.78 , pp. 155-165
    • Meng, Q.1    Qi, M.2    Chen, D.Z.3
  • 54
    • 2342541774 scopus 로고    scopus 로고
    • Adenosine induces apoptosis in the human gastric cancer cells via an intrinsic pathway relevant to activation of AMP-activated protein kinase
    • Saitoh M, Nagai K, Nakagawa K, Yamamura T, Yamamoto S, Nishizaki T: Adenosine induces apoptosis in the human gastric cancer cells via an intrinsic pathway relevant to activation of AMP-activated protein kinase. Biochem Pharmacol 2004;67: 2005-2011.
    • (2004) Biochem Pharmacol , vol.67 , pp. 2005-2011
    • Saitoh, M.1    Nagai, K.2    Nakagawa, K.3    Yamamura, T.4    Yamamoto, S.5    Nishizaki, T.6
  • 55
    • 34047145398 scopus 로고    scopus 로고
    • Intracellularly transported adenosine induces apoptosis in HuH-7 human hepatoma cells by downregulating c-FLIP expression causing caspase-3/-8 activation
    • Yang D, Yaguchi T, Yamamoto H, Nishizaki T: Intracellularly transported adenosine induces apoptosis in HuH-7 human hepatoma cells by downregulating c-FLIP expression causing caspase-3/-8 activation. Biochem Pharmacol 2007;73:1665-1675.
    • (2007) Biochem Pharmacol , vol.73 , pp. 1665-1675
    • Yang, D.1    Yaguchi, T.2    Yamamoto, H.3    Nishizaki, T.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.