Adenosine induces apoptosis in the human gastric cancer cells via an intrinsic pathway relevant to activation of AMP-activated protein kinase

Biochemical Pharmacology

Volumn 67, Issue 10, 2004, Pages 2005-2011

  Saitoh, Masaru ^a   Nagai, Kaoru ^a   Nakagawa, Kazuhiko ^a   Yamamura, Takehira ^a   Yamamoto, Satoshi ^a   Nishizaki, Tomoyuki ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

3 (4,5 dimethyl 2 thiazolyl) 2,5 diphenyl 2H tetrazolium bromide; 8 cyclopentyltheophylline; 8 CPT; AIF; AMP activated protein kinase; AMPK; apoptosis inducing factor; DMPX; MTT; PBS; phosphate buffered saline; single stranded DNA; ssDNA

Indexed keywords

3,7 DIMETHYL 1 PROPARGYLXANTHINE; 5' AMINO 5' DEOXYADENOSINE; 8 CYCLOPENTYLTHEOPHYLLINE; ADENOSINE; ADENOSINE A1 RECEPTOR ANTAGONIST; ADENOSINE A2A RECEPTOR ANTAGONIST; ADENOSINE KINASE INHIBITOR; ADENOSINE RECEPTOR; AMINOIMIDAZOLE 4 CARBOXAMIDE RIBONUCLEOSIDE; CASPASE; CASPASE 3; CASPASE 3 INHIBITOR; CASPASE 4; CASPASE 8; CASPASE 8 INHIBITOR; CASPASE 9; CASPASE INHIBITOR; CELL MARKER; DIPYRIDAMOLE; HOE 33342; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INTERLEUKIN 1BETA CONVERTING ENZYME; RECEPTOR BLOCKING AGENT; RIBONUCLEOSIDE DERIVATIVE; SINGLE STRANDED DNA; THEOPHYLLINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER CELL CULTURE; CELL DEATH; CELL NUCLEUS; CELL TRANSPORT; CELL VIABILITY; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; DRUG MECHANISM; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; HUMAN; HUMAN CELL; INHIBITION KINETICS; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; PRIORITY JOURNAL; STOMACH CANCER; TIME;

ADENINE; ADENOSINE; ADENYLATE KINASE; AMINOIMIDAZOLE CARBOXAMIDE; APOPTOSIS; CASPASES; DIPYRIDAMOLE; DRUG INTERACTIONS; ENZYME ACTIVATION; HUMANS; MEMBRANE POTENTIALS; MITOCHONDRIA; RECEPTORS, PURINERGIC P1; RIBONUCLEOTIDES; SIGNAL TRANSDUCTION; STOMACH NEOPLASMS; TUMOR CELLS, CULTURED;

EID: 2342541774     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2004.01.020     Document Type: Article

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