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Volumn 38, Issue 3, 2011, Pages 761-767

Ganodermanontriol, a lanostanoid triterpene from Ganoderma lucidum, suppresses growth of colon cancer cells through β-catenin signaling

Author keywords

catenin; Colon cancer; Cyclin D1; Ganoderma lucidum; Ganodermanontriol

Indexed keywords

BETA CATENIN; CYCLIN D1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN E; GANODERMANONTRIOL; PROTEIN P21; TRITERPENE DERIVATIVE; UNCLASSIFIED DRUG; UVOMORULIN;

EID: 79952025254     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2011.898     Document Type: Article
Times cited : (58)

References (45)
  • 1
    • 42949142609 scopus 로고    scopus 로고
    • Systemic treatment of colorectal cancer
    • Wolpin BM and Mayer RJ: Systemic treatment of colorectal cancer. Gastroenterology 134: 1296-1310, 2008.
    • (2008) Gastroenterology , vol.134 , pp. 1296-1310
    • Wolpin, B.M.1    Mayer, R.J.2
  • 6
    • 0033615352 scopus 로고    scopus 로고
    • PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs
    • DOI 10.1016/S0092-8674(00)81664-5
    • He TC, Chan TA, Vogelstein B and Kinzler KW: PPARdelta is an APC-regulated target of nonsteroidal anti-inflammatory drugs. Cell 99: 335-345, 1999. (Pubitemid 29519912)
    • (1999) Cell , vol.99 , Issue.3 , pp. 335-345
    • He, T.-C.1    Chan, T.A.2    Vogelstein, B.3    Kinzler, K.W.4
  • 7
    • 0033119801 scopus 로고    scopus 로고
    • Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells
    • DOI 10.1038/18884
    • Tetsu O and McCormick F: Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 398: 422-426, 1999. (Pubitemid 29180374)
    • (1999) Nature , vol.398 , Issue.6726 , pp. 422-426
    • Tetsu, O.1    McCormick, F.2
  • 8
    • 0031438751 scopus 로고    scopus 로고
    • Transforming growth factor-alpha enhances cyclin D1 transcription through the binding of early growth response protein to a cis-regulatory element in the cyclin D1 promoter
    • DOI 10.1074/jbc.272.52.33181
    • Yan YX, Nakagawa H, Lee MH and Rustgi AK: Transforming growth factor-alpha enhances cyclin D1 transcription through the binding of early growth response protein to a cis-regulatory element in the cyclin D1 promoter. J Biol Chem 272: 33181-33190, 1997. (Pubitemid 28023664)
    • (1997) Journal of Biological Chemistry , vol.272 , Issue.52 , pp. 33181-33190
    • Yan, Y.-X.1    Nakagawa, H.2    Lee, M.-H.3    Rustgi, A.K.4
  • 11
    • 77549083008 scopus 로고    scopus 로고
    • Secondary metabolites from higher fungi: Discovery, bioactivity, and bioproduction
    • Zhong JJ and Xiao JH: Secondary metabolites from higher fungi: discovery, bioactivity, and bioproduction. Adv Biochem Eng Biotechnol 113: 79-150, 2009.
    • (2009) Adv Biochem Eng Biotechnol , vol.113 , pp. 79-150
    • Zhong, J.J.1    Xiao, J.H.2
  • 12
    • 77953924040 scopus 로고    scopus 로고
    • The in vitro and in vivo experimental evidences disclose the chemopreventive effects of Ganoderma lucidum on cancer invasion and metastasis
    • Weng CJ and Yen GC: The in vitro and in vivo experimental evidences disclose the chemopreventive effects of Ganoderma lucidum on cancer invasion and metastasis. Clin Exp Metastasis 27: 361-369, 2010.
    • (2010) Clin Exp Metastasis , vol.27 , pp. 361-369
    • Weng, C.J.1    Yen, G.C.2
  • 13
    • 0036595422 scopus 로고    scopus 로고
    • New triterpene aldehydes, lucialdehydes A-C, from Ganoderma lucidum and their cytotoxicity against murine and human tumor cells
    • Tokyo
    • Gao JJ, Min BS, Ahn EM, Nakamura N, Lee HK and Hattori M: New triterpene aldehydes, lucialdehydes A-C, from Ganoderma lucidum and their cytotoxicity against murine and human tumor cells. Chem Pharm Bull (Tokyo) 50: 837-840, 2002.
    • (2002) Chem Pharm Bull , vol.50 , pp. 837-840
    • Gao, J.J.1    Min, B.S.2    Ahn, E.M.3    Nakamura, N.4    Lee, H.K.5    Hattori, M.6
  • 14
    • 0037432498 scopus 로고    scopus 로고
    • Triterpene-enriched extracts from Ganoderma lucidum inhibit growth of hepatoma cells via suppressing protein kinase C, activating mitogen-activated protein kinases and G2-phase cell cycle arrest
    • Lin SB, Li CH, Lee SS and Kan LS: Triterpene-enriched extracts from Ganoderma lucidum inhibit growth of hepatoma cells via suppressing protein kinase C, activating mitogen-activated protein kinases and G2-phase cell cycle arrest. Life Sci 72: 2381-2390, 2003.
    • (2003) Life Sci , vol.72 , pp. 2381-2390
    • Lin, S.B.1    Li, C.H.2    Lee, S.S.3    Kan, L.S.4
  • 15
    • 77953988178 scopus 로고    scopus 로고
    • Triterpenes from Ganoderma lucidum induce autophagy in colon cancer through the inhibition of p38 mitogen-activated kinase (p38 MAPK)
    • Thyagarajan A, Jedinak A, Nguyen H, Terry C, Baldridge LA, Jiang J and Sliva D: Triterpenes from Ganoderma lucidum induce autophagy in colon cancer through the inhibition of p38 mitogen-activated kinase (p38 MAPK). Nutr Cancer 62: 630-640, 2010.
    • (2010) Nutr Cancer , vol.62 , pp. 630-640
    • Thyagarajan, A.1    Jedinak, A.2    Nguyen, H.3    Terry, C.4    Baldridge, L.A.5    Jiang, J.6    Sliva, D.7
  • 17
    • 0031795507 scopus 로고    scopus 로고
    • Triterpenes from the spores of Ganoderma lucidum and their inhibitory activity against HIV-1 protease
    • Tokyo
    • Min BS, Nakamura N, Miyashiro H, Bae KW and Hattori M: Triterpenes from the spores of Ganoderma lucidum and their inhibitory activity against HIV-1 protease. Chem Pharm Bull (Tokyo) 46: 1607-1612, 1998.
    • (1998) Chem Pharm Bull , vol.46 , pp. 1607-1612
    • Min, B.S.1    Nakamura, N.2    Miyashiro, H.3    Bae, K.W.4    Hattori, M.5
  • 18
    • 0035668974 scopus 로고    scopus 로고
    • Anticomplement activity of terpenoids from the spores of Ganoderma lucidum
    • Min BS, Gao JJ, Hattori M, Lee HK and Kim YH: Anticomplement activity of terpenoids from the spores of Ganoderma lucidum. Planta Med 67: 811-814, 2001.
    • (2001) Planta Med , vol.67 , pp. 811-814
    • Min, B.S.1    Gao, J.J.2    Hattori, M.3    Lee, H.K.4    Kim, Y.H.5
  • 19
    • 59049106559 scopus 로고    scopus 로고
    • Pleurotus ostreatus inhibits proliferation of human breast and colon cancer cells through p53-dependent as well as p53-independent pathway
    • Jedinak A and Sliva D: Pleurotus ostreatus inhibits proliferation of human breast and colon cancer cells through p53-dependent as well as p53-independent pathway. Int J Oncol 33: 1307-1313, 2008.
    • (2008) Int J Oncol , vol.33 , pp. 1307-1313
    • Jedinak, A.1    Sliva, D.2
  • 21
    • 0036479114 scopus 로고    scopus 로고
    • Phosphatidylinositol 3-kinase and NF-κB regulate motility of invasive MDA-MB-231 human breast cancer cells by the secretion of urokinase-type plasminogen activator
    • DOI 10.1074/jbc.M109579200
    • Sliva D, Rizzo MT and English D: Phosphatidylinositol 3-kinase and NF-κB regulate motility of invasive MDA-MB-231 human breast cancer cells by the secretion of urokinase-type plasminogen activator (uPA). J Biol Chem 277: 3150-3157, 2002. (Pubitemid 34953176)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.5 , pp. 3150-3157
    • Sliva, D.1    Rizzo, M.T.2    English, D.3
  • 22
    • 0032891720 scopus 로고    scopus 로고
    • E-cadherin binding prevents beta-catenin nuclear localization and beta-catenin/LEF-1-mediated transactivation
    • Orsulic S, Huber O, Aberle H, Arnold S and Kemler R: E-cadherin binding prevents beta-catenin nuclear localization and beta-catenin/LEF-1-mediated transactivation. J Cell Sci 112: 1237-1245, 1999. (Pubitemid 29218912)
    • (1999) Journal of Cell Science , vol.112 , Issue.8 , pp. 1237-1245
    • Orsulic, S.1    Huber, O.2    Aberle, H.3    Arnold, S.4    Kemler, R.5
  • 24
    • 33744736933 scopus 로고    scopus 로고
    • The antitumor effect of a novel differentiation inducer, 2, 2-Bis (4-(4-amino-3-hydroxyphenoxy) phenyl) adamantane (DPA), in combinatory therapy on human colon cancer
    • Wang JJ, Lee JY, Chen YC, Chern YT and Chi CW: The antitumor effect of a novel differentiation inducer, 2, 2-Bis (4-(4-amino-3-hydroxyphenoxy) phenyl) adamantane (DPA), in combinatory therapy on human colon cancer. Int J Oncol 28: 1003-1012, 2006.
    • (2006) Int J Oncol , vol.28 , pp. 1003-1012
    • Wang, J.J.1    Lee, J.Y.2    Chen, Y.C.3    Chern, Y.T.4    Chi, C.W.5
  • 25
    • 73349109760 scopus 로고    scopus 로고
    • Triterpenoids as new promising anticancer drugs
    • Petronelli A, Pannitteri G and Testa U: Triterpenoids as new promising anticancer drugs. Anticancer Drugs 20: 880-892, 2009.
    • (2009) Anticancer Drugs , vol.20 , pp. 880-892
    • Petronelli, A.1    Pannitteri, G.2    Testa, U.3
  • 27
    • 79952009837 scopus 로고    scopus 로고
    • Medicinal potential of Ganoderma lucidum
    • Rai M and Bridge PD (eds). CAB International, Oxon, Cambridge
    • Sliva D: Medicinal potential of Ganoderma lucidum. In: Applied Mycology. Rai M and Bridge PD (eds). CAB International, Oxon, Cambridge, pp173-196, 2009.
    • (2009) Applied Mycology , pp. 173-196
    • Sliva, D.1
  • 28
    • 34548598182 scopus 로고    scopus 로고
    • Ganoderma lucidum and its pharmaceutically active compounds
    • Boh B, Berovic M, Zhang J and Lin ZB: Ganoderma lucidum and its pharmaceutically active compounds. Biotechnol Annu Rev 13: 265-301, 2007.
    • (2007) Biotechnol Annu Rev , vol.13 , pp. 265-301
    • Boh, B.1    Berovic, M.2    Zhang, J.3    Lin, Z.B.4
  • 29
    • 76649092309 scopus 로고    scopus 로고
    • Development of a new method for improved identification and relative quantification of unknown metabolites in complex samples: Determination of a triterpenoid metabolic fingerprint for the in situ characterization of Ganoderma bioactive compounds
    • Adamec J, Jannasch A, Dudhgaonkar S, Jedinak A, Sedlak M and Sliva D: Development of a new method for improved identification and relative quantification of unknown metabolites in complex samples: determination of a triterpenoid metabolic fingerprint for the in situ characterization of Ganoderma bioactive compounds. J Sep Sci 32: 4052-4058, 2009.
    • (2009) J Sep Sci , vol.32 , pp. 4052-4058
    • Adamec, J.1    Jannasch, A.2    Dudhgaonkar, S.3    Jedinak, A.4    Sedlak, M.5    Sliva, D.6
  • 30
    • 67650732691 scopus 로고    scopus 로고
    • Metabolism and pharmacokinetics in rats of ganoderiol F, a highly cytotoxic and antitumor triterpene from Ganoderma lucidum
    • Zhang Q, Zuo F, Nakamura N, Ma CM and Hattori M: Metabolism and pharmacokinetics in rats of ganoderiol F, a highly cytotoxic and antitumor triterpene from Ganoderma lucidum. J Nat Med 63: 304-310, 2009.
    • (2009) J Nat Med , vol.63 , pp. 304-310
    • Zhang, Q.1    Zuo, F.2    Nakamura, N.3    Ma, C.M.4    Hattori, M.5
  • 31
    • 46449138184 scopus 로고    scopus 로고
    • Ganoderic acids suppress growth and invasive behavior of breast cancer cells by modulating AP-1 and NF-kappaB signaling
    • Jiang J, Grieb B, Thyagarajan A and Sliva D: Ganoderic acids suppress growth and invasive behavior of breast cancer cells by modulating AP-1 and NF-kappaB signaling. Int J Mol Med 21: 577-584, 2008.
    • (2008) Int J Mol Med , vol.21 , pp. 577-584
    • Jiang, J.1    Grieb, B.2    Thyagarajan, A.3    Sliva, D.4
  • 33
    • 33845231348 scopus 로고    scopus 로고
    • Ganoderic acid T from Ganoderma lucidum mycelia induces mitochondria mediated apoptosis in lung cancer cells
    • Tang W, Liu JW, Zhao WM, Wei DZ and Zhong JJ: Ganoderic acid T from Ganoderma lucidum mycelia induces mitochondria mediated apoptosis in lung cancer cells. Life Sci 80: 205-211, 2006.
    • (2006) Life Sci , vol.80 , pp. 205-211
    • Tang, W.1    Liu, J.W.2    Zhao, W.M.3    Wei, D.Z.4    Zhong, J.J.5
  • 34
    • 18844383202 scopus 로고    scopus 로고
    • Ganoderic acid X, a lanostanoid triterpene, inhibits topoisomerases and induces apoptosis of cancer cells
    • Li CH, Chen PY, Chang UM, Kan LS, Fang WH, Tsai KS and Lin SB: Ganoderic acid X, a lanostanoid triterpene, inhibits topoisomerases and induces apoptosis of cancer cells. Life Sci 77: 252-265, 2005.
    • (2005) Life Sci , vol.77 , pp. 252-265
    • Li, C.H.1    Chen, P.Y.2    Chang, U.M.3    Kan, L.S.4    Fang, W.H.5    Tsai, K.S.6    Lin, S.B.7
  • 35
    • 47049128697 scopus 로고    scopus 로고
    • Lucidenic acid B induces apoptosis in human leukemia cells via a mitochondria-mediated pathway
    • Hsu CL, Yu YS and Yen GC: Lucidenic acid B induces apoptosis in human leukemia cells via a mitochondria-mediated pathway. J Agric Food Chem 56: 3973-3980, 2008.
    • (2008) J Agric Food Chem , vol.56 , pp. 3973-3980
    • Hsu, C.L.1    Yu, Y.S.2    Yen, G.C.3
  • 36
    • 1542347695 scopus 로고    scopus 로고
    • Convergence of Wnt, beta-Catenin, and Cadherin pathways
    • DOI 10.1126/science.1094291
    • Nelson WJ and Nusse R: Convergence of Wnt, beta-catenin, and cadherin pathways. Science 303: 1483-1487, 2004. (Pubitemid 38314410)
    • (2004) Science , vol.303 , Issue.5663 , pp. 1483-1487
    • Nelson, W.J.1    Nusse, R.2
  • 37
    • 18044373963 scopus 로고    scopus 로고
    • Decisions, decisions: beta-catenin chooses between adhesion and transcription
    • DOI 10.1016/j.tcb.2005.03.002
    • Harris TJ and Peifer M: Decisions, decisions: beta-catenin chooses between adhesion and transcription. Trends Cell Biol 15: 234-237, 2005. (Pubitemid 40603891)
    • (2005) Trends in Cell Biology , vol.15 , Issue.5 , pp. 234-237
    • Harris, T.J.C.1    Peifer, M.2
  • 38
    • 0031692261 scopus 로고    scopus 로고
    • Cytomechanics of cadherin-mediated cell-cell adhesion
    • DOI 10.1016/S0955-0674(98)80031-8
    • Adams CL and Nelson WJ: Cytomechanics of cadherin-mediated cell-cell adhesion. Curr Opin Cell Biol 10: 572-577, 1998. (Pubitemid 28477014)
    • (1998) Current Opinion in Cell Biology , vol.10 , Issue.5 , pp. 572-577
    • Adams, C.L.1    Nelson, W.J.2
  • 39
    • 0030272281 scopus 로고    scopus 로고
    • Cadherins and catenins in development
    • DOI 10.1016/S0955-0674(96)80110-4
    • Huber O, Bierkamp C and Kemler R: Cadherins and catenins in development. Curr Opin Cell Biol 8: 685-691, 1996. (Pubitemid 26381726)
    • (1996) Current Opinion in Cell Biology , vol.8 , Issue.5 , pp. 685-691
    • Huber, O.1    Bierkamp, C.2    Kemler, R.3
  • 40
    • 0345343608 scopus 로고    scopus 로고
    • Nuclear localization of beta-catenin by interaction with transcription factor LEF-1
    • DOI 10.1016/0925-4773(96)00597-7
    • Huber O, Korn R, McLaughlin J, Ohsugi M, Herrmann BG and Kemler R: Nuclear localization of beta-catenin by interaction with transcription factor LEF-1. Mech Dev 59: 3-10, 1996. (Pubitemid 26325455)
    • (1996) Mechanisms of Development , vol.59 , Issue.1 , pp. 3-10
    • Huber, O.1    Korn, R.2    McLaughlin, J.3    Ohsugi, M.4    Herrmann, B.G.5    Kemler, R.6
  • 41
    • 28344433073 scopus 로고    scopus 로고
    • Deconstructing the cadherin-catenin-actin complex
    • DOI 10.1016/j.cell.2005.09.020, PII S0092867405009748
    • Yamada S, Pokutta S, Drees F, Weis WI and Nelson WJ: Deconstructing the cadherin-catenin-actin complex. Cell 123: 889-901, 2005. (Pubitemid 41721034)
    • (2005) Cell , vol.123 , Issue.5 , pp. 889-901
    • Yamada, S.1    Pokutta, S.2    Drees, F.3    Weis, W.I.4    Nelson, W.J.5
  • 42
    • 0032510494 scopus 로고    scopus 로고
    • A causal role for E-cadherin in the transition from adenoma to carcinoma
    • DOI 10.1038/32433
    • Perl AK, Wilgenbus P, Dahl U, Semb H and Christofori G: A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature 392: 190-193, 1998. (Pubitemid 28162793)
    • (1998) Nature , vol.392 , Issue.6672 , pp. 190-193
    • Peri, A.-K.1    Wilgenbus, P.2    Dahl, U.3    Semb, H.4    Christofori, G.5
  • 44
    • 0034042381 scopus 로고    scopus 로고
    • Suppression of breast cancer invasion and migration by indole-3- Carbinol: Associated with up-regulation of BRCA1 and E-cadherin/catenin complexes
    • Meng Q, Qi M, Chen DZ, Yuan R, Goldberg ID, Rosen EM, Auborn K and Fan S: Suppression of breast cancer invasion and migration by indole-3-carbinol: associated with up-regulation of BRCA1 and E-cadherin/catenin complexes. J Mol Med 78: 155-165, 2000. (Pubitemid 30337497)
    • (2000) Journal of Molecular Medicine , vol.78 , Issue.3 , pp. 155-165
    • Meng, Q.1    Qi, M.2    Chen, D.-Z.3    Yuan, R.4    Goldberg, I.D.5    Rosen, E.M.6    Auborn, K.7    Fan, S.8


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