The augmented anti-tumor effects of Antrodia camphorata co-fermented with Chinese medicinal herb in human hepatoma cells

American Journal of Chinese Medicine

Volumn 37, Issue 4, 2009, Pages 771-783

  Li, Shun Lai ^a   Huang, Zih Ning ^a   Hsieh, Hsiao Hui ^a   Yu, Wen Chun ^a   Tzeng, Win Yu ^a   Lee, Guo Yang ^a   Chen, Yi Peng ^a   Chang, Chia Yu ^a,b   Chuu, Jiunn Jye ^a,c  

^a SOUTHERN TAIWAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^b CHI MEI MEDICAL CENTER   (Taiwan)

^c Wei Gong Memorial Hospital   (Taiwan)

Author keywords

A. camphorata; Co fermentation; Hepatoma; Mitomycin

Indexed keywords

ANTRODIA CAMPHORATA EXTRACT; CHINESE DRUG; CISPLATIN; CYCLOOXYGENASE 2; GLYCYRRHIZA EXTRACT; METHOTREXATE; MITOMYCIN C; MULTIDRUG RESISTANCE PROTEIN 1; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; PACLITAXEL; PROTEIN KINASE B; UNCLASSIFIED DRUG;

ADJUVANT THERAPY; ANTINEOPLASTIC ACTIVITY; ANTRODIA CAMPHORATA; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G0 PHASE; CELL PROLIFERATION; CELL STRAIN HEPG2; CHINESE MEDICINE; CONTROLLED STUDY; DOWN REGULATION; EXTRACTIVE FERMENTATION; FRUITING BODY; FUNGUS; FUNGUS CULTURE; GLYCYRRHIZA; HEPATOMA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; SOLID STATE FERMENTATION; UPREGULATION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS; ANTRODIA; APOPTOSIS; BLOTTING, WESTERN; CARCINOMA, HEPATOCELLULAR; CELL CYCLE; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; CYCLOOXYGENASE 2; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; FERMENTATION; FRUITING BODIES, FUNGAL; HUMANS; LIVER NEOPLASMS; MITOMYCIN; NUCLEIC ACID SYNTHESIS INHIBITORS; P-GLYCOPROTEIN; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-AKT;

EID: 69049116370     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X09007235     Document Type: Article

References (26)

1. Chang, C.Y., Z.N. Huang, H.H. Yu, L.H. Chang, S.L. Li, Y.P. Chen, K.Y. Lee and J.J. Chuu. The adjuvant effects of Antrodia camphorate extracts combined with anti-tumor agents on multidrug resistant human hepatoma cells. J. Ethnopharmacol. 118: 387-395, 2008.
2. Chen, C.J., M.W. Yu and Y.F. Liaw. Epidemiological characteristics and risk factors of hepatocellular carcinoma. J. Gastroenterol. Hepatol. 12(9/10): 294-308, 1997.
3. Hsiao, G., M.Y. Shen, K.H. Lin, M.H. Lan, L.Y. Wu, D.S. Chou, C.H. Lin, C.H. Su and J.R. Sheu. Antioxidative and hepatoprotective effects of Antrodia camphorate extract. J. Agric. Food Chem. 51: 3302-3308, 2003.
4. Hsu, Y.L., Y.C. Kuo, P.L. Kuo, L.T. Ng, Y.H. Kuo and C.C. Lin. Apoptotic effects of extract from Antrodia camphorate fruiting bodies in human hepatocellular carcinoma cell lines. Cancer Lett. 221: 77-89, 2005.
5. Hsu, Y.L., P.L. Kuo, C.Y. Cho, W.C. Ni, T.F. Tzeng, L.T. Ng, Y.H. Kuo and C.C. Lin. Antrodia cinnamomea fruiting bodies extract suppresses the invasive potential of human liver cancer cell line PLC/ PRF/5 through inhibition of nuclear factor κ B pathway. Food Chem. Toxicol. 45: 1249-1257, 2007.
6. Jin, W., K.W. Scotto, W.N. Hait and J.M. Yang. Involvement of CtBP1 in the transcriptional activation of the MDR1 gene in human multidrug resistant cancer cells. Biochem. Pharmacol. 74: 851-859, 2007.
7. Kamazawa, S., J. Kigawa, Y. Kanamori, H. Itamochi, S. Sato, T. Iba and N. Terakawa. Multidrug resistance gene-1 is a useful predictor of paclitaxel-based chemotherapy for patientswith ovarian cancer. Gynecol. Oncol. 86: 171-176, 2002.
8. Kardosh, A., N. Soriano, Y.T. Liu, J. Uddin, N.A. Petasis, I.M. Hofman, T.C. Chen and A.H. Schönthal. Multitarget inhibition of drug-resistant multiple myeloma cell lines by dimethyl-celecoxib (DMC), a non-COX-2 inhibitory analog of celecoxib. Blood 106: 4330-4338, 2005.
9. Komuro, Y., Y. Udagawa, N. Susumu, D. Aoki, T. Kubota and S. Nozawa. Paclitaxel and SN-38 overcome cisplatin resistance of ovarian cancer cell lines by down-regulating the influx and efflux system of cisplatin. Jpn. J. Cancer Res. 92(11): 1242-1250, 2005.
10. Leng, J., C. Han, A.J. Demetris, K. Georgr, G.K. Michalopoulos and T. Wu. Cyclooxygenase-2 promotes hepatocellular carcinoma cell growth through AKT activation: Evidence for AKT inhibition in celecoxib-induced apoptosis. Hepatology 38: 756-768, 2003.
11. Li, Y., Y. Yang, L. Fang, Z. Zhang, J. Jin and K. Zhang. Anti-hepatitis activities in the broth of Ganoderma lucidum supplemented with a Chinese herbal medicine. Am. J. Chin. Med. 34: 341-349, 2006.
12. Liu, J.J., T.S. Huang, M.L. Hsu, C.C. Chen, W.S. Lin, F.J. Lu and W.H. Chang. Antitumor effects of the partially purified polysaccharides from Antrodia camphorata and the mechanism of its action. Toxicol. Appl. Pharmacol. 201: 186-193, 2004.
13. Liu, D.Z., H.J. Liang, C.H. Chen, C.H. Su, T.H. Lee, C.T. Huang, W.C. Hou, S.Y. Lin, W.B. Zhong, P.J. Lin, L.F. Hung and Y.C. Liang. Comparative anti-inflammatory characterization of wild fruiting body, liquid-state fermentation, and solid-state culture of Taiwanofungus camphoratus in microglia and the mechanism of its action. J. Ethnopharmacol. 113: 45-53, 2007.
14. 2+], and MAPKs phosphorylation in MG63 human osteosarcoma cells. Drug Dev. Res. 68: 71-78, 2007.
15. Park, I.C., M.J. Park, C.S. Hwang, C.H. Rhee, D.Y. Whang, J.J. Jang, T.B. Choe, S.I. Hong and S.H. Lee. Mitomycin C induces apoptosis in a caspases-dependent and Fas/CD95- independent manner in human gastric adenocarcinoma cells. Cancer Lett. 158: 125-132. 2000.
16. Pirnia, F., E. Schneider, D.C. Betticher and M.M. Borner. MitomycinCinduces apoptosis and caspase-8 and -9 processing through a caspase-3 and Fas-independent pathway. Cell Death Differ. 9: 905-914, 2002.
17. Rafi, M.M., R.T. Rosen, A.Vassil, C.T. Ho, H. Zhang, G. Ghai, G. Lambert and R.S. DiPaola. Modulation of bcl-2 and cytotoxicity by licochalcone-A, a novel estrogenic flavonoid. Anticancer Res. 20: 2653-2658, 2000.
18. Rao, Y.K., S.H. Fang and Y.M. Tzeng. Evaluation of the anti-inflammatory and anti-proliferation tumoral cells activities of Antrodia camphorata, Cordyceps sinensis, and Cinnamomum osmophloeum bark extracts. J. Ethnopharmacol. 114: 78-85, 2007.
19. Shih, I.L.,K. Pan and C.Hsieh. Influence of nutritional components and oxygen supply on the mycelial growth and bioactive metabolites production in submerged culture of Antrodia cinnamomea. Process. Biochem. 41: 1129-1135, 2006.
20. Song, T.Y., S.L. Hsu and G.C. Yen. Induction of apoptosis in human hepatoma cells by mycelia of Antrodia camphorata in submerged culture. J. Ethnopharmacol. 100: 158-167, 2005a.
21. Song, T.Y., S.L. Hsu, C.T. Yeh and G.C. Yen. Mycelia from Antrodia camphorata in submerged culture induce apoptosis of human hepatoma HepG2 cells possibly through regulation of Fas pathway. J. Agric. Food Chem. 53: 5559-5564, 2005b.
22. Wang, Z.Y. and D.W. Nixon. Licorice and cancer. Nutr. Cancer 39: 1-11, 2001.
23. Wu, H., C.L. Pan, Y.C. Yao, S.S. Chang, S.L. Li and T.F. Wu. Proteomic analysis of the effect of Antrodia camphorata extract on human lung cancer A549 cell. Proteomics 6: 826-835, 2006.
24. Yang, H.L., C.S. Chen, W.H. Chang, F.J. Lu, Y.C. Lai, C.C. Chen, T.H. Hseu, C.T. Kuo and Y.C. Hseu. Growth inhibition and induction of apoptosis in MCF-7 breast cancer cells by Antrodia camphorata. Cancer Lett. 231: 215-227, 2006.
25. Zalipsky, S., M. Saad, R. Kiwan, E. Ber, N. Yu and T. Minko. Antitumor activity of new liposomal prodrug of mitomycin C in multidrug resistant solid tumor: Insights of the mechanism of action. J. Drug Target. 5: 518-530, 2007.
26. Zatelli, M.C., A. Luchin, F. Tagliati, S. Leoni, D. Piccin, M. Bondanelli, R. Rossi and E.C. degli Uberti. Cyclooxygenase-2 inhibitors prevent the development of chemoresistance phenotype in a breast cancer cell line by inhibiting glycoprotein p-170 expression. Endocr. Relat. Cancer 14: 1029-1038, 2007.