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Volumn 135, Issue 2, 2013, Pages 208-216

In silico and in vitro comparative activity of novel experimental derivatives against Leishmania major and Leishmania infantum promastigotes

Author keywords

Antileishmanial activity; Biurets; In silico; In vitro; MTT

Indexed keywords

MEGLUMINE ANTIMONATE; PTERIDINE DERIVATIVE;

EID: 84882608082     PISSN: 00144894     EISSN: 10902449     Source Type: Journal    
DOI: 10.1016/j.exppara.2013.07.004     Document Type: Article
Times cited : (27)

References (53)
  • 1
    • 84855973558 scopus 로고    scopus 로고
    • Microbial control of malaria: biological warfare against the parasite and its vector
    • Abdul-Ghani R., Al-Mekhlafi A.M., Alabsi M.S. Microbial control of malaria: biological warfare against the parasite and its vector. Acta Trop. 2012, 121(2):71-84.
    • (2012) Acta Trop. , vol.121 , Issue.2 , pp. 71-84
    • Abdul-Ghani, R.1    Al-Mekhlafi, A.M.2    Alabsi, M.S.3
  • 2
    • 84881524107 scopus 로고    scopus 로고
    • In silico designing selective inhibitor of drugs, medicinal plants compounds and experimental ligands for pteridine reductase targeting visceral leishmaniasis
    • Adibpour N., Rahim F., Rezaeei S., Khalaj A., Ebrahimi A. In silico designing selective inhibitor of drugs, medicinal plants compounds and experimental ligands for pteridine reductase targeting visceral leishmaniasis. Afr. J. Microbiol. Res. 2012, 6(5):917-926.
    • (2012) Afr. J. Microbiol. Res. , vol.6 , Issue.5 , pp. 917-926
    • Adibpour, N.1    Rahim, F.2    Rezaeei, S.3    Khalaj, A.4    Ebrahimi, A.5
  • 3
    • 82755163896 scopus 로고    scopus 로고
    • Detection of drug resistance gene in cutaneous leishmaniasis by PCR in some endemic areas of iran
    • Alizadeh R., Hooshyar H., Bandehpor M., Arbabi M., Kazemi F., Talari A., et al. Detection of drug resistance gene in cutaneous leishmaniasis by PCR in some endemic areas of iran. Iran. Red Crescent Med. J. 2011, 13(12):863-867.
    • (2011) Iran. Red Crescent Med. J. , vol.13 , Issue.12 , pp. 863-867
    • Alizadeh, R.1    Hooshyar, H.2    Bandehpor, M.3    Arbabi, M.4    Kazemi, F.5    Talari, A.6
  • 4
    • 0034772197 scopus 로고    scopus 로고
    • A policy for leishmaniasis with respect to the prevention and control of drug resistance
    • Bryceson A. A policy for leishmaniasis with respect to the prevention and control of drug resistance. Trop. Med. Int. Health 2001, 6(11):928-934.
    • (2001) Trop. Med. Int. Health , vol.6 , Issue.11 , pp. 928-934
    • Bryceson, A.1
  • 6
  • 7
    • 77953562409 scopus 로고    scopus 로고
    • Glycobiology of the Leishmania parasite and emerging targets for antileishmanial drug discovery
    • Chandra S., Ruhela D., Deb A., Vishwakarma R.A. Glycobiology of the Leishmania parasite and emerging targets for antileishmanial drug discovery. Expert Opin. Ther. Targets 2010, 14(7):739-757.
    • (2010) Expert Opin. Ther. Targets , vol.14 , Issue.7 , pp. 739-757
    • Chandra, S.1    Ruhela, D.2    Deb, A.3    Vishwakarma, R.A.4
  • 8
    • 77957320017 scopus 로고    scopus 로고
    • Drug targets in Leishmania
    • Chawla B., Madhubala R. Drug targets in Leishmania. J. Parasit. Dis. 2010, 34(1):1-13.
    • (2010) J. Parasit. Dis. , vol.34 , Issue.1 , pp. 1-13
    • Chawla, B.1    Madhubala, R.2
  • 9
    • 0027180507 scopus 로고
    • Verification of protein structures: patterns of nonbonded atomic interactions
    • Colovos C., Yeates T.O. Verification of protein structures: patterns of nonbonded atomic interactions. Protein Sci. 1993, 2(9):1511-1519.
    • (1993) Protein Sci. , vol.2 , Issue.9 , pp. 1511-1519
    • Colovos, C.1    Yeates, T.O.2
  • 10
    • 0036172167 scopus 로고    scopus 로고
    • Geno3D: automatic comparative molecular modelling of protein
    • Combet C., Jambon M., Deleage G., Geourjon C. Geno3D: automatic comparative molecular modelling of protein. Bioinformatics 2002, 18(1):213-214.
    • (2002) Bioinformatics , vol.18 , Issue.1 , pp. 213-214
    • Combet, C.1    Jambon, M.2    Deleage, G.3    Geourjon, C.4
  • 11
    • 0004305780 scopus 로고
    • Report of a WHO Expert Committee
    • Control of the Leishmaniases
    • Control of the Leishmaniases Report of a WHO Expert Committee. World Health Organ. Tech. Rep. Ser. 1990, 793:1-158.
    • (1990) World Health Organ. Tech. Rep. Ser. , vol.793 , pp. 1-158
  • 12
    • 0034771454 scopus 로고    scopus 로고
    • Monitoring drug resistance in leishmaniasis
    • Croft S.L. Monitoring drug resistance in leishmaniasis. Trop. Med. Int. Health 2001, 6(11):899-905.
    • (2001) Trop. Med. Int. Health , vol.6 , Issue.11 , pp. 899-905
    • Croft, S.L.1
  • 14
    • 15744385718 scopus 로고    scopus 로고
    • Recent advances in antileishmanial drug development
    • Davis A.J., Kedzierski L. Recent advances in antileishmanial drug development. Curr. Opin. Investig. Drugs 2005, 6(2):163-169.
    • (2005) Curr. Opin. Investig. Drugs , vol.6 , Issue.2 , pp. 163-169
    • Davis, A.J.1    Kedzierski, L.2
  • 15
    • 0141909066 scopus 로고    scopus 로고
    • Proteome mapping of the protozoan parasite Leishmania and application to the study of drug targets and resistance mechanisms
    • Drummelsmith J., Brochu V., Girard I., Messier N., Ouellette M. Proteome mapping of the protozoan parasite Leishmania and application to the study of drug targets and resistance mechanisms. Mol. Cell. Proteomics 2003, 2(3):146-155.
    • (2003) Mol. Cell. Proteomics , vol.2 , Issue.3 , pp. 146-155
    • Drummelsmith, J.1    Brochu, V.2    Girard, I.3    Messier, N.4    Ouellette, M.5
  • 16
    • 78651093844 scopus 로고    scopus 로고
    • Virtual screening identification of nonfolate compounds, including a CNS drug, as antiparasitic agents inhibiting pteridine reductase
    • Ferrari S., Morandi F., Motiejunas D., Nerini E., Henrich S., Luciani R., et al. Virtual screening identification of nonfolate compounds, including a CNS drug, as antiparasitic agents inhibiting pteridine reductase. J. Med. Chem. 2011, 54(1):211-221.
    • (2011) J. Med. Chem. , vol.54 , Issue.1 , pp. 211-221
    • Ferrari, S.1    Morandi, F.2    Motiejunas, D.3    Nerini, E.4    Henrich, S.5    Luciani, R.6
  • 17
    • 77957596613 scopus 로고    scopus 로고
    • Synthesis and cytotoxicity of some biurets against human breast cancer T47D cell line
    • Fouladdel S., Khalaj A., Adibpour N., Azizi E. Synthesis and cytotoxicity of some biurets against human breast cancer T47D cell line. Bioorg. Med. Chem. Lett. 2010, 20(19):5772-5775.
    • (2010) Bioorg. Med. Chem. Lett. , vol.20 , Issue.19 , pp. 5772-5775
    • Fouladdel, S.1    Khalaj, A.2    Adibpour, N.3    Azizi, E.4
  • 18
    • 41549148210 scopus 로고    scopus 로고
    • Anticancer compounds as leishmanicidal drugs: challenges in chemotherapy and future perspectives
    • Fuertes M.A., Nguewa P.A., Castilla J., Alonso C., Perez J.M. Anticancer compounds as leishmanicidal drugs: challenges in chemotherapy and future perspectives. Curr. Med. Chem. 2008, 15(5):433-439.
    • (2008) Curr. Med. Chem. , vol.15 , Issue.5 , pp. 433-439
    • Fuertes, M.A.1    Nguewa, P.A.2    Castilla, J.3    Alonso, C.4    Perez, J.M.5
  • 19
    • 84855424019 scopus 로고    scopus 로고
    • Identification of novel inhibitors of dipeptidylcarboxypeptidase of Leishmania donovani via ligand-based virtual screening and biological evaluation
    • Gangwar S., Baig M.S., Shah P., Biswas S., Batra S., Siddiqi M.I., et al. Identification of novel inhibitors of dipeptidylcarboxypeptidase of Leishmania donovani via ligand-based virtual screening and biological evaluation. Chem. Biol. Drug Des. 2012, 79(2):149-156.
    • (2012) Chem. Biol. Drug Des. , vol.79 , Issue.2 , pp. 149-156
    • Gangwar, S.1    Baig, M.S.2    Shah, P.3    Biswas, S.4    Batra, S.5    Siddiqi, M.I.6
  • 20
    • 0026769377 scopus 로고
    • Drug resistance in leishmaniasis: its implication in systemic chemotherapy of cutaneous and mucocutaneous disease
    • Grogl M., Thomason T.N., Franke E.D. Drug resistance in leishmaniasis: its implication in systemic chemotherapy of cutaneous and mucocutaneous disease. Am. J. Trop. Med. Hyg. 1992, 47(1):117-126.
    • (1992) Am. J. Trop. Med. Hyg. , vol.47 , Issue.1 , pp. 117-126
    • Grogl, M.1    Thomason, T.N.2    Franke, E.D.3
  • 21
    • 78751684265 scopus 로고    scopus 로고
    • In silico screening, structure-activity relationship, and biologics evaluation of selective pteridine reductase inhibitors targeting visceral leishmaniasis
    • Kaur J., Kumar P., Tyagi S., Pathak R., Batra S., Singh P., et al. In silico screening, structure-activity relationship, and biologics evaluation of selective pteridine reductase inhibitors targeting visceral leishmaniasis. Antimicrob. Agents Chemother. 2011, 55(2):659-666.
    • (2011) Antimicrob. Agents Chemother. , vol.55 , Issue.2 , pp. 659-666
    • Kaur, J.1    Kumar, P.2    Tyagi, S.3    Pathak, R.4    Batra, S.5    Singh, P.6
  • 22
    • 84892482349 scopus 로고    scopus 로고
    • Bioinformatic analysis of leishmania donovani long-chain fatty acid-CoA ligase as a novel drug target
    • Kaur J., Tiwari R., Kumar A., Singh N. Bioinformatic analysis of leishmania donovani long-chain fatty acid-CoA ligase as a novel drug target. Mol. Biol. Int. 2011, 2011:278051.
    • (2011) Mol. Biol. Int. , vol.2011 , pp. 278051
    • Kaur, J.1    Tiwari, R.2    Kumar, A.3    Singh, N.4
  • 24
    • 79953284018 scopus 로고    scopus 로고
    • Miltefosine-induced apoptotic cell death on Leishmania major and L. tropica strains
    • Khademvatan S., Gharavi M.J., Rahim F., Saki J. Miltefosine-induced apoptotic cell death on Leishmania major and L. tropica strains. Korean J. Parasitol. 2011, 49(1):17-23.
    • (2011) Korean J. Parasitol. , vol.49 , Issue.1 , pp. 17-23
    • Khademvatan, S.1    Gharavi, M.J.2    Rahim, F.3    Saki, J.4
  • 25
    • 48849097750 scopus 로고    scopus 로고
    • Leishmania donovani pteridine reductase 1: biochemical properties and structure-modeling studies
    • Kumar P., Kumar A., Verma S.S., Dwivedi N., Singh N., Siddiqi M.I., et al. Leishmania donovani pteridine reductase 1: biochemical properties and structure-modeling studies. Exp. Parasitol. 2008, 120(1):73-79.
    • (2008) Exp. Parasitol. , vol.120 , Issue.1 , pp. 73-79
    • Kumar, P.1    Kumar, A.2    Verma, S.S.3    Dwivedi, N.4    Singh, N.5    Siddiqi, M.I.6
  • 26
    • 77956591314 scopus 로고    scopus 로고
    • EasyModeller: a graphical interface to MODELLER
    • Kuntal B.K., Aparoy P., Reddanna P. EasyModeller: a graphical interface to MODELLER. BMC Res Notes 2010, 3:226.
    • (2010) BMC Res Notes , vol.3 , pp. 226
    • Kuntal, B.K.1    Aparoy, P.2    Reddanna, P.3
  • 28
    • 74049122035 scopus 로고    scopus 로고
    • Drug resistance in visceral leishmaniasis
    • Maltezou H.C. Drug resistance in visceral leishmaniasis. J. Biomed. Biotechnol. 2010, 2010:617521.
    • (2010) J. Biomed. Biotechnol. , vol.2010 , pp. 617521
    • Maltezou, H.C.1
  • 29
    • 0021182871 scopus 로고
    • Evaluation of a range of antimicrobial agents against the parasitic protozoa, Plasmodium falciparum, Babesia rodhaini and Theileria parva in vitro
    • McColm A.A., McHardy N. Evaluation of a range of antimicrobial agents against the parasitic protozoa, Plasmodium falciparum, Babesia rodhaini and Theileria parva in vitro. Ann. Trop. Med. Parasitol. 1984, 78(4):345-354.
    • (1984) Ann. Trop. Med. Parasitol. , vol.78 , Issue.4 , pp. 345-354
    • McColm, A.A.1    McHardy, N.2
  • 31
    • 84857056158 scopus 로고    scopus 로고
    • Anti-malarial, anti-trypanosomal, and anti-leishmanial activities of jacaranone isolated from Pentacalia desiderabilis (Vell.) Cuatrec. (Asteraceae)
    • Morais T.R., Romoff P., Favero O.A., Reimao J.Q., Lourenco W.C., Tempone A.G., et al. Anti-malarial, anti-trypanosomal, and anti-leishmanial activities of jacaranone isolated from Pentacalia desiderabilis (Vell.) Cuatrec. (Asteraceae). Parasitol. Res. 2012, 110(1):95-101.
    • (2012) Parasitol. Res. , vol.110 , Issue.1 , pp. 95-101
    • Morais, T.R.1    Romoff, P.2    Favero, O.A.3    Reimao, J.Q.4    Lourenco, W.C.5    Tempone, A.G.6
  • 32
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 1983, 65(1-2):55-63.
    • (1983) J. Immunol. Methods , vol.65 , Issue.1-2 , pp. 55-63
    • Mosmann, T.1
  • 33
    • 29144480979 scopus 로고    scopus 로고
    • Protein kinases as drug targets in trypanosomes and Leishmania
    • Naula C., Parsons M., Mottram J.C. Protein kinases as drug targets in trypanosomes and Leishmania. Biochim. Biophys. Acta 2005, 1754(1-2):151-159.
    • (2005) Biochim. Biophys. Acta , vol.1754 , Issue.1-2 , pp. 151-159
    • Naula, C.1    Parsons, M.2    Mottram, J.C.3
  • 34
    • 53049090855 scopus 로고    scopus 로고
    • Leishmaniasis: drug resistance and natural products (Review)
    • Polonio T., Efferth T. Leishmaniasis: drug resistance and natural products (Review). Int. J. Mol. Med. 2008, 22(3):277-286.
    • (2008) Int. J. Mol. Med. , vol.22 , Issue.3 , pp. 277-286
    • Polonio, T.1    Efferth, T.2
  • 35
    • 84862026244 scopus 로고    scopus 로고
    • In silico analysis of a therapeutic target in Leishmania infantum: the guanosine-diphospho-d-mannose pyrophosphorylase
    • Pomel S., Rodrigo J., Hendra F., Cave C., Loiseau P.M. In silico analysis of a therapeutic target in Leishmania infantum: the guanosine-diphospho-d-mannose pyrophosphorylase. Parasite 2012, 19(1):63-70.
    • (2012) Parasite , vol.19 , Issue.1 , pp. 63-70
    • Pomel, S.1    Rodrigo, J.2    Hendra, F.3    Cave, C.4    Loiseau, P.M.5
  • 36
    • 85042599316 scopus 로고    scopus 로고
    • Selective leishmanicidal effect of 1,3,4-thiadiazole derivatives and possible mechanism of action against Leishmania species
    • Poorrajab F., Ardestani S.K., Foroumadi A., Emami S., Kariminia A., Behrouzi-Fardmoghadam M., et al. Selective leishmanicidal effect of 1,3,4-thiadiazole derivatives and possible mechanism of action against Leishmania species. Exp. Parasitol. 2009, 121(4):323-330.
    • (2009) Exp. Parasitol. , vol.121 , Issue.4 , pp. 323-330
    • Poorrajab, F.1    Ardestani, S.K.2    Foroumadi, A.3    Emami, S.4    Kariminia, A.5    Behrouzi-Fardmoghadam, M.6
  • 37
    • 77957937242 scopus 로고    scopus 로고
    • Leishmaniasis in the World Health Organization Eastern Mediterranean Region
    • Postigo J.A. Leishmaniasis in the World Health Organization Eastern Mediterranean Region. Int. J. Antimicrob. Agents 2010, 36(Suppl. 1):S62-S65.
    • (2010) Int. J. Antimicrob. Agents , vol.36 , Issue.SUPPL. 1
    • Postigo, J.A.1
  • 38
    • 33846057724 scopus 로고    scopus 로고
    • NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins
    • (Database issue)
    • Pruitt K.D., Tatusova T., Maglott D.R. NCBI reference sequences (RefSeq): a curated non-redundant sequence database of genomes, transcripts and proteins. Nucleic Acids Res. 2007, 35:D61-D65. (Database issue).
    • (2007) Nucleic Acids Res. , vol.35
    • Pruitt, K.D.1    Tatusova, T.2    Maglott, D.R.3
  • 39
    • 58149178579 scopus 로고    scopus 로고
    • NCBI reference sequences: current status, policy and new initiatives
    • (Database issue)
    • Pruitt K.D., Tatusova T., Klimke W., Maglott D.R. NCBI reference sequences: current status, policy and new initiatives. Nucleic Acids Res. 2009, 37:D32-D36. (Database issue).
    • (2009) Nucleic Acids Res. , vol.37
    • Pruitt, K.D.1    Tatusova, T.2    Klimke, W.3    Maglott, D.R.4
  • 40
    • 77949871989 scopus 로고    scopus 로고
    • An in silico development of selective inhibitor for histamine receptors
    • Rahim F. An in silico development of selective inhibitor for histamine receptors. Biotechnology 2010, 9:157-163.
    • (2010) Biotechnology , vol.9 , pp. 157-163
    • Rahim, F.1
  • 42
    • 78649757228 scopus 로고    scopus 로고
    • MPI-PHYLIP: parallelizing computationally intensive phylogenetic analysis routines for the analysis of large protein families
    • Ropelewski A.J., Nicholas H.B., Gonzalez Mendez R.R. MPI-PHYLIP: parallelizing computationally intensive phylogenetic analysis routines for the analysis of large protein families. PLoS One 2010, 5(11):e13999.
    • (2010) PLoS One , vol.5 , Issue.11
    • Ropelewski, A.J.1    Nicholas, H.B.2    Gonzalez Mendez, R.R.3
  • 43
    • 80055006678 scopus 로고    scopus 로고
    • Immunomodulation by chemotherapeutic agents against Leishmaniasis
    • Saha P., Mukhopadhyay D., Chatterjee M. Immunomodulation by chemotherapeutic agents against Leishmaniasis. Int. Immunopharmacol. 2011, 11(11):1668-1679.
    • (2011) Int. Immunopharmacol. , vol.11 , Issue.11 , pp. 1668-1679
    • Saha, P.1    Mukhopadhyay, D.2    Chatterjee, M.3
  • 44
    • 0042622380 scopus 로고    scopus 로고
    • SWISS-MODEL: an automated protein homology-modeling server
    • Schwede T., Kopp J., Guex N., Peitsch M.C. SWISS-MODEL: an automated protein homology-modeling server. Nucleic Acids Res. 2003, 31(13):3381-3385.
    • (2003) Nucleic Acids Res. , vol.31 , Issue.13 , pp. 3381-3385
    • Schwede, T.1    Kopp, J.2    Guex, N.3    Peitsch, M.C.4
  • 45
    • 84934439857 scopus 로고    scopus 로고
    • Arsenite resistance in Leishmania and possible drug targets
    • Singh G., Jayanarayan K.G., Dey C.S. Arsenite resistance in Leishmania and possible drug targets. Adv. Exp. Med. Biol. 2008, 625:1-8.
    • (2008) Adv. Exp. Med. Biol. , vol.625 , pp. 1-8
    • Singh, G.1    Jayanarayan, K.G.2    Dey, C.S.3
  • 46
    • 0034780949 scopus 로고    scopus 로고
    • Drug resistance in Indian visceral leishmaniasis
    • Sundar S. Drug resistance in Indian visceral leishmaniasis. Trop. Med. Int. Health 2001, 6(11):849-854.
    • (2001) Trop. Med. Int. Health , vol.6 , Issue.11 , pp. 849-854
    • Sundar, S.1
  • 47
    • 0031881116 scopus 로고    scopus 로고
    • Do the diminishing efficacy and increasing toxicity of sodium stibogluconate in the treatment of visceral leishmaniasis in Bihar, India, justify its continued use as a first-line drug? An observational study of 80 cases
    • Thakur C.P., Sinha G.P., Pandey A.K., Kumar N., Kumar P., Hassan S.M., et al. Do the diminishing efficacy and increasing toxicity of sodium stibogluconate in the treatment of visceral leishmaniasis in Bihar, India, justify its continued use as a first-line drug? An observational study of 80 cases. Ann. Trop. Med. Parasitol. 1998, 92(5):561-569.
    • (1998) Ann. Trop. Med. Parasitol. , vol.92 , Issue.5 , pp. 561-569
    • Thakur, C.P.1    Sinha, G.P.2    Pandey, A.K.3    Kumar, N.4    Kumar, P.5    Hassan, S.M.6
  • 48
    • 76149120388 scopus 로고    scopus 로고
    • AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading
    • Trott O., Olson A.J. AutoDock Vina: improving the speed and accuracy of docking with a new scoring function, efficient optimization, and multithreading. J. Comput. Chem. 2010, 31(2):455-461.
    • (2010) J. Comput. Chem. , vol.31 , Issue.2 , pp. 455-461
    • Trott, O.1    Olson, A.J.2
  • 50
    • 3342943546 scopus 로고    scopus 로고
    • Possible mechanism of miltefosine-mediated death of Leishmania donovani
    • Verma N.K., Dey C.S. Possible mechanism of miltefosine-mediated death of Leishmania donovani. Antimicrob. Agents Chemother. 2004, 48(8):3010-3015.
    • (2004) Antimicrob. Agents Chemother. , vol.48 , Issue.8 , pp. 3010-3015
    • Verma, N.K.1    Dey, C.S.2
  • 51
    • 78650974605 scopus 로고    scopus 로고
    • Antileishmanial activity of benzocycloalkyl azole oximino ethers: the conformationally constraint analogues of oxiconazole
    • Verma A., Srivastava S., Sane S.A., Marrapu V.K., Srinivas N., Yadav M., et al. Antileishmanial activity of benzocycloalkyl azole oximino ethers: the conformationally constraint analogues of oxiconazole. Acta Trop. 2011, 117(2):157-160.
    • (2011) Acta Trop. , vol.117 , Issue.2 , pp. 157-160
    • Verma, A.1    Srivastava, S.2    Sane, S.A.3    Marrapu, V.K.4    Srinivas, N.5    Yadav, M.6
  • 52
    • 84882692955 scopus 로고    scopus 로고
    • W.H.O. Control of the leishmaniases. Geneva
    • W.H.O. Control of the leishmaniases. Geneva; 2010.
    • (2010)


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