Detection of drug resistance gene in cutaneous leishmaniasis by PCR in some endemic area of Iran

Iranian Red Crescent Medical Journal

Volumn 13, Issue 12, 2011, Pages

  Alizadeh, R ^a   Hooshyar, H ^a   Bandehpor, M ^b   Arbabi, M ^a   Kazemi, F ^a   Talari, A ^a   Kazemi, B ^b  

^a KASHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Cutaneous leishmaniasis; Drug resistance; Iran; PCR

Indexed keywords

DNA; MULTIDRUG RESISTANCE PROTEIN 1;

ARTICLE; CONTROLLED STUDY; DNA EXTRACTION; DNA SEQUENCE; ENDEMIC DISEASE; GENE MUTATION; GENETIC ANALYSIS; GIEMSA STAIN; HUMAN; HUMAN CELL; IRAN; LEISHMANIA MAJOR; LEISHMANIA TROPICA; MAJOR CLINICAL STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; SKIN LEISHMANIASIS; SKIN ULCER;

EID: 82755163896     PISSN: 20741804     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (22)

1. Pérez-Victoria JM, Pérez-Victoria FJ, Parodi-Talice A, Jiménez IA, Ravelo AG, Castanys S, Gamarro F. Alkyl-lysophospholipid resistance in multidrug-resistant Leishmania tropica and chemosensitization by a novel P-glycoprotein-like transporter modulator. Antimicrob Agents Chemother 2001;45:2468-74. [11502516] [http://dx.doi.org/10.1128/AAC.45.9. 2468-2474.2001]
2. Sundar S, More DK, Singh MK, Singh VP, Sharma S, Makharia A, Kumar PC, Murray HW. Failure of pentavalent antimony in visceral leishmaniasis in India: report from the center of the Indian epidemic. Clin Infect Dis 2000;31:1104-7. [110 49798] [http://dx.doi.org/10.1086/318121]
3. Momeni A. Treatment of cutaneous leishmaniasis In: Nadim A, Javadian E, Mohebali M,Momeni A. Leishmaniose and Leishmania parasite 3rd Ed.University Press Center, Tehran 2009; p. 68-88.
4. Ponte-Sucre A. Physiological consequences of drug resistance in Leishmania and their relevance for chemotherapy. Kinetoplastid Biol Dis 2003;2:14. [14613496] [http://dx. doi.org/10.1186/1475-9292-2-14]
5. Ullman B. Multidrug resistance and P-glycoproteins in parasitic protozoa. J Bioenerg Biomembr 1995; 27:77-84. [7629055] [http://dx.doi. org/10.1007/BF02110334]
6. Enk CD, Fritsch C, Jonas F, Nasereddin A, Ingber A, Jaffe CL, Ruzicka T. Treatment of cutaneous leishmaniasis with photodynamic therapy. Arch Dermatol 2003; 139:432-4. [12707088] [http://dx.doi. org/10.1001/archderm.139.4.432]
7. Hendrickson N, Sifri CD, Henderson DM, Allen T, Wirth DF, Ullman B. Molecular characterization of the ldmdr1 multidrug resistance gene from Leishmania donovani. Mol Biochem Parasitol 1993;60:53-64. [8103567] [http://dx.doi.org/10.1016/ 0166-6851(93)90028-V]
8. Berman JD. Human leishmaniasis: clinical, diagnostic, and chemotherapeutic developments in the last 10 years. Clin Infect Dis 1997;24:684-703. [9145744] [http://dx.doi.org/ 10.1093/clind/24.4.684]
9. Brochu C, Wang J, Roy G, Messier N, Wang XY, Saravia NG, Ouellette M. Antimony uptake systems in the protozoan parasite Leishmania and accumulation differences in antimonyresistant parasites. Antimicrob Agents Chemother 2003;47:3073-9. [14506011] [http://dx.doi.org/10.11 28/AAC.47.10.3073-3079.2003]
10. Bern C, Chowdhury R. The epidemiology of visceral leishmaniasis in Bangladesh: prospects for improved control. Indian J Med Res 2006; 123:275-88. [16778310]
11. DosReis GA. Susceptible hosts: a resort for parasites right in the eye of the immune response. An Acad Bras Cienc 2000;72:79-82. [10932 108] [http://dx.doi.org/10.1590/S000 1-37652000000100011]
12. Hadighi R, Boucher P, Khamesipour A, Meamar AR, Roy G, Ouellette M, Mohebali M. Glucantime-resistant Leishmania tropica isolated from Iranian patients with cutaneous leishmaniasis are sensitive to alternative antileishmania drugs. Parasitol Res 2007;101:1319-22. [176100 79] [http://dx.doi.org/10.1007/s004 36-007-0638-0]
13. Hadighi R, Mohebali M, Boucher P, Hajjaran H, Khamesipour A, Ouellette M. Unresponsiveness to Glucantime treatment in Iranian cutaneous leishmaniasis due to drugresistant Leishmania tropica parasites. PLoS Med 2006;3:e162. [1660 5301] [http://dx.doi.org/10.1371/journal. pmed.0030162]
14. Sam brooks J, Fritsch F, Maiatis T. Molecular cloning: A laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press. Cold Spring Harbor, NY, 1989; p. E3-E4.
15. Mehrabani D, Motazedian Mh, Asgari Q, Hatam GR, Owji SM, Oryan A. Leishmania major in Tatera indica in Estahban, southern Iran: Microscopy, culture, isoenzyme, and PCR. Pak J Med Sci 2011;27:734-738.
16. Mehrabani D, Motazedian MH, Hatam GR, Asgari Q, Owji SM, Oryan A. Leishmania major in Tatera Drug resistance gene in leishmaniasis indica in Fasa, southern Iran: Microscopy, culture, isoenzyme, PCR and morphologic study. AJAVA 2011;6:255-264. [http://dx.doi.org/ 10.3923/ajava.2011.255.264]
17. Mehrabani D, Motazedian MH, Oryan A, Asqari Q, Hatam GR. A search for the rodent hosts of Leishmania major in the Larestan region of southern Iran: Demonstration of the parasite in Tatera indica and Gerbillus sp., by microscopy, culture and PCR. Ann Trop Med Parasitol 2007;101:1-9. [http://dx. doi.org/10.1179/136485907X17644 5] [17524246]
18. Henderson DM, Sifri CD, Rodgers M, Wirth DF, Hendrickson N, Ullman B. Multidrug resistance in Leishmania donovani is conferred by amplification of a gene homologous to the mammalian mdr1 gene. Mol Cell Biol 1992;12:2855-65. [1350325]
19. Légaré D, Hettema E, Ouellette M. The P-glycoprotein-related gene family in Leishmania. Mol Biochem Parasitol 1994;68:81-91. [7891750] [http://dx.doi.org/10.1016/0166-6851(94)00156-1]
20. Ephros M, Waldman E, Zilberstein D. Pentostam induces resistance to antimony and the preservative chlorocresol in Leishmania donovani promastigotes and axenically grown amastigotes. Antimicrob Agents Chemother 1997;41:1064-8. [9145870]
21. Ouellette M, Légaré D, Haimeur A, Grondin K, Roy G, Brochu C, Papadopoulou B. ABC transporters in Leishmania and their role in drug resistance. Drug Resist Updat 1998;1:43-8. [17092795] [http://dx. doi.org/10.1016/S1368-7646(98)80213-6]
22. Ouellette M, Borst P. Drug resistance and P-glycoprotein gene amplification in the protozoan parasite Leishmania. Res Microbiol 1991; 142:737-46. [http://dx.doi.org/10.1016/0923-2508(91)90089-S]