Stabilization of the transcription factor Foxp3 by the deubiquitinase USP7 increases treg-cell-suppressive capacity

Immunity

Volumn 39, Issue 2, 2013, Pages 259-271

  vanLoosdregt, Jorg ^a,b   Fleskens, Veerle ^a   Fu, Juan ^c   Brenkman, ArjanB ^a   Bekker, CornelisP J ^a,d   Pals, CorneliekeE G M ^a   Meerding, Jenny ^b   Berkers, CeliaR ^f   Barbi, Joseph ^c   Gröne, Andrea ^e   Sijts, AliceJ A M ^d   Maurice, MadelonM ^a   Kalkhoven, Eric ^a   Prakken, BerentJ ^b   Ovaa, Huib ^e   Pan, Fan ^c   Zaiss, DietmarM W ^d   Coffer, PaulJ ^a,b  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c JOHNS HOPKINS UNIVERSITY   (United States)

^d Department of Infectious Diseases and Immunology   (Netherlands)

^e Faculty of Veterinary Medicine   (Netherlands)

^f NETHERLANDS CANCER INSTITUTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 2; INTERLEUKIN 6; MESSENGER RNA; TRANSCRIPTION FACTOR FOXP3; UBIQUITIN;

ACETYLATION; ADOPTIVE TRANSFER; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DIFFERENTIATION; CELL SURVIVAL; CONTROLLED STUDY; DISEASE SEVERITY; IN VITRO STUDY; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN STABILITY; REGULATORY T LYMPHOCYTE; UBIQUITINATION;

ADOPTIVE TRANSFER; ANIMALS; CELL DIFFERENTIATION; CELL LINE; COLITIS; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; ENDOPEPTIDASES; FORKHEAD TRANSCRIPTION FACTORS; HEK293 CELLS; HOMEODOMAIN PROTEINS; HUMANS; IMMEDIATE-EARLY PROTEINS; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; RNA INTERFERENCE; RNA, SMALL INTERFERING; T-LYMPHOCYTES, REGULATORY; UBIQUITIN THIOLESTERASE; UBIQUITINATION;

EID: 84882592280     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2013.05.018     Document Type: Article

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