Mechanical cues for cell culture

Handbook of Biofunctional Surfaces

Volumn , Issue , 2013, Pages 865-898

  Melzak, K A ^a,b   Moreno Flores1, S ^b   Vivanco, M ^c   Toca Herrera, Jose Luis* ^b  

^a CIC BIOMAGUNE   (Spain)

^b UNIVERSITY OF NATURAL RESOURCES AND LIFE SCIENCES   (Austria)

^c CIC BIOGUNE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

MECHANICAL CUES;

CELL CULTURE;

EID: 84881836302     PISSN: None     EISSN: None     Source Type: Book    
DOI: None     Document Type: Chapter

References (102)

1. Freshney, R. I. Culture of Animal Cells (John Wiley & Sons, Hoboken, NJ), 2005.
2. Uhlenhuth, E. The form of epithelial cells in cultures of frog skin, and its relation to the consistency of the medium. J. Exp. Med., 22, 76-104, 1915.
3. Discher, D. E., Janmey, P. and Wang, Y.-L. Tissue cells feel and respond to the stiffness of their substrate. Science, 310, 1139-1143, 2005.
4. Discher, D. E., Mooney, D. J. and Zandstra, P. W. Growth factors, matrices, and forces combine and control stem cells. Science, 324, 1673-1677, 2009.
5. Engler, A. J., Griffin, M. A., Sen, S., Bönneman, C. G., Sweeney, H. L. and Discher, D. E. Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments. J. Cell Biol., 166, 877-887, 2004.
6. Jacot, J. G., McCulloch, A. D. and Omens, J. H. Substrate stiffness affects the functional maturation of neonatal rat ventricular myocytes. Biophys. J., 95, 3479-3487, 2008.
7. Georges, P. C., Hui, J., Gombos, Z., McCormick, M. E., Wang, A. Y., Uemura, M., Mick, R., Janmey, P. A., Furth, E. E. and Wells, R. G. Increased stiffness of the rat liver precedes matrix deposition: implications for fibrosis. Am. J. Physiol. Gastroinest. Liver Physiol., 293, G1147-G1154, 2007.
8. Pittenger, M. F. and Martin, B. J. Mesenchymal stem cells and their potential as cardiac therapeutics. Circ. Res., 95, 9-20, 2004.
9. Flanagan, L. A., Ju, Y., Marg, B., Osterfield, M. and Janmey, P. A. Neurite branching on deformable substrates. Dev. Neurosci., 13, 2411-2415, 2002.
10. Georges, P. C. and Janmey, P. A. Cell type-specific response to growth on soft materials. J. Appl. Physiol., 98, 1547-1553, 2005.
11. Levental, I., Georges, P. C. and Janmey, P. A. Soft biological materials and their impact on cell function. Soft Matter, 3, 299-306, 2007.
12. McDaniel, D. P., Shaw, G. A., Elliott, J. T., Bhadriraju, K., Meuse, C., Chung, K. and Plant, A. L. The stiffness of collagen fibrils influences vascular smooth muscle cell phenotype. Biophys. J., 92, 1759-1769, 2007.
13. Ghosh, K., Pan, Z., Guan, E., Ge, S., Liu, Y., Nakamura, T., Ren, X., Rafailovich, M. and Clark, R. A. F. Cell adaptation to a physiologically relevant ECM mimic with different viscoelastic properties. Biomaterials, 28, 671-679, 2007. Mechanical Cues for Cell Culture
14. Schwartz, M. A., Lechene, C. and Ingber, D. E. Insoluble fibronectin activates the Na/H antiporter by clustering and immobilizing integrin α5β1, independent of cell shape. Proc. Nat. Acad. Sci. USA, 88, 7849-7853, 1991.
15. Cukierman, E., Pankov and Yamada, K. M., Cell interactions with threedimensional matrices. Curr. Opin. Cell Biol., 14, 633-639, 2002.
16. Elsdale, T. and Bard, J. Collagen substrata for studies on cell behavior. J. Cell Biol., 54, 626-637, 1972.
17. Pedersen, J. A. and Swartz, M. A. Mechanobiology in the third dimension. Ann. Biomed. Eng., 33, 1469-1490, 2005.
18. Chen, C. S., Mrksich, M., Huang, S., Whitesides, G. M. and Ingber, D. E. Geometric control of cell life and death. Science, 276, 1425-1428, 1997.
19. Arnold, M., Cavalcanti-Adam, E. A., Glass, R., Blümmel, J., Eck, W., Kantlehner, M., Kessler, H. and Spatz, J. P. Activation of integrin function by nanopatterned adhesive interfaces. ChemPhysChem, 5, 383-388, 2004.
20. Lodish, H., Berk, A., Zipursky, L., Matsudaira, P. and Darnell, J. Molecular Cell Biology, 5th ed. (W. H. Freeman and Company), 2003.
21. Kim, B.-S. and Mooney, D. J. Development of biocompatible synthetic extracellular matrices for tissue engineering. Tibtech, 16, 224-230, 1998.
22. Töyräs, J., Lyyra-Laitinen, T., Niinimäki, M., Lindgren, M., Nieminen, M. T., Kiviranta, I. and Jurvelin, J. S. Estimation of the Young's modulus of articular cartilage using an arthroscopic indentation instrument and ultrasonic measurement of tissue thickness. J. Biomech., 34, 251-256, 2001.
23. Jin, H. and Lewis, J. L. Determination of Poissons ratio of articular cartilage by indentation using different-sized indenters. J. Biomech. Eng. T. ASME, 126, 138-145, 2004.
24. Freed, L. E., Langer, R., Martin, I., Pellis, N. R. and Vunjak-Novakovic, G. Tissue engineering of cartilage in space. Proc. Natl. Acad. Sci. USA, 94, 13885-13890, 1997.
25. Guilak F., Alexopoulos L. G., Haider M. A., Ting-Beall H. P. and Setton L. A. Zonal uniformity in mechanical properties of the chondrocyte pericellular matrix: micropipette aspiration of canine chondrons isolated by cartilage homogenization. Ann. Biomed. Eng., 33, 1312-1318, 2005. 891
26. Kleinman, H. K. and Martin, G. R. Matrigel: basement membrane matrix with biological activity. Semin. Cancer Biol., 15, 378-386, 2005.
27. The Matrigel composition is described in the BD Biosciences catalogue at http://viewer. zmags. com/publication/d5d7952b?page_124#d5d7952b/124.
28. Kleinman, H. K., McGarvey, M. L., Liotta, L. A., Gehron Robey, P., Truggvasson, K. and Martin, G. R. Isolation and characterization of type IV procollagen, laminin, and heparan sulfate proteoglycan from the EHS sarcoma. Biochemistry, 21, 6188-6193, 1982.
29. Soofi, S. S., Last, J. A., Liliensiek, S. J., Nealey, P. F. and Murphy, C. J. The elastic modulus of MatrigelTM as determined by atomic force microscopy. J. Struct. Biol., 167, 216-219, 2009.
30. Reed, J., Walczak, W. J., Petzold, O. N. and Gimzewski, J. K. In situ mechanical interferometry of Matrigel films. Langmuir, 25, 36-39, 2009.
31. Nijenhuis, N., Mizuno, D., Spaan, J. A. E. and Schmidt, C. F. Viscoelastic response of a model endothelial glycocalyx. Phys. Biol., 6, 1-8, 2009.
32. Fisher, H. W., Puck, T. T. and Sato, G. Molecular growth requirements of single mammalian cell: the action of fetuin in promoting cell attachment to glass. Proc. Nat. Acad. Sci USA, 44, 4-10, 1958.
33. Smith, H. L., Hickey, J., Jablin, M. S., Trujillo, A., Freyer, J. P. and Majewski, J. Mouse fibroblast cell adhesion studied by neutron reflectometry. Biophys. J., 98, 793-799, 2010.
34. Miyake, K., Satomi, N. and Sasaki, S. Elastic modulus of polystyrene film from near surface to bulk measured by nanoindentation using atomic force microscopy. Appl. Phys. Lett., 89, 031925, 2006.
35. Melzak, K. A. and Brooks, D. E. Modification of silica with a covalently attached antigen for use in immunosorbent assays. In Proteins at Interfaces II-Fundamentals and Applications, eds. Horbett, T. A. and Brash, J. L. (Symposium Sergies, San Diego), 1995.
36. del Campo, A., Boos, D., Spiess H. W. and Jonas, U. Surface modification with orthogonal photosensitive silanes for sequential chemical lithography and site-selective particle deposition. Angew. Chem., Int. Ed., 44, 4707-4712, 2005.
37. Kulkarni, S., Syed, A., Singh, S., Gaikwad, A., Patil, K., Vijayamohanan, K., Ahmad, A. and Ogale, S. Silicate nanoparticles by bioleaching of glass and modification of the glass surface. J. Non-Cryst. Solids, 354, 3433-3437, 2008. Mechanical Cues for Cell Culture
38. Alcaraz, J., Xu, R., Mori, H., Nelson, C. M., Mroue, R., Spencer, V. A., Brownfield, D., Radisky, D. C., Bustamante, C. and Bissell, M. J. Laminin and biomimetic extracellular elasticity enhance functional differentiation in mammary epithelia. EMBO J., 27, 2829-2838, 2008.
39. Paszek, M. J., Zahir, N., Johnson, K. R., Lakins, J. N., Rozenberg, G. I., Gefen, A., Reinhart-King, C. A., Margulies, S. S., Dembo M., Boettiger, D., Hammer, D. A. and Weaver, V. M. Tensional homeostasis and the malignant phenotype. Cancer Cell, 8, 241-254, 2005.
40. Féréol, S., Fodil, R., Labat, B., Galiacy, S., Laurent, V. M., Louis, B., Isabey, D. and Planus, E. Sensitivity of alveolar macrophages to substrate mechanical and adhesive properties. Cell Motil. Cytoskel., 63, 321-340, 2006.
41. Maruguchi, T., Maruguchi, Y., Suzuki, S., Matsuda, K., Toda, K. I. and Isskiki, N. A new skin equivalent-keratinocytes proliferated and differentiated on collagen sponge containing fibroblasts. Plast. Reconstr. Surg., 93, 537-544, 1994.
42. Asselineau, D. and Prunieras, M. Reconstruction of "simplified" skin: control of fabrication. Brit. J. Dermatol., 111(27), 219-222, 1984.
43. Kohen, N. T., Little, L. E. and Healy, K. E. Characterization of Matrigel interfaces during defined human embryonic cell culture. Biointerphases, 4, 69-79, 2009.
44. van der Rest, M. and Garrone, R. Collagen family of proteins. FASEB J., 5, 2814-2823, 1991.
45. Kadler, K. E., Holmes, D. F., Trotter, J. A. and Chapman, J. A. Collagen fibril formation. Biochem. J., 316, 1-11, 1996.
46. Kleinman, H. K., Klebe, R. J. and Martin, G. R. Role of collagenous matrices in the adhesion and growth of cells. J. Cell Biol., 88, 473-485, 1981.
47. Gelse, K., Pöschl, E. and Aigner, T. Collagens-structure, function, and biosynthesis. Adv. Drug Delivery Rev., 55, 1531-1546, 2003.
48. Bailey, A. J., Paul, R. G. and Knott, L. Mechanisms of maturation and ageing of collagen. Mech. Ageing Dev., 106, 1-56, 1998.
49. Bayliss, M. and Somers, G. Isolation and culture of human hepatocytes. In Methods in Molecular Medicine, Vol. 107-Human Cell Culture Protocols, 2nd ed., ed. Picot, J. (Humana Press, Totowa, NJ).
50. Guidry, A. and O'Brien, C. A bovine mammary endothelial/epithelial cell culture model of the blood/milk barrier. In Methods in Molecular Biology, Vol. 188-Epithelial Cell Culture Protocols, ed. Wise, C. (Humana Press, Totowa, NJ). 893
51. Murray J. C., Stingl, G., Kleinman, H. K., Martin G. R. and Katz, S. I. Epidermal cells adhere preferentially to type IV (basement membrane) collagen. J. Cell Biol., 80, 197-202, 1979.
52. Wicha, M. S., Liotta, L. A., Garbisa, S. and Kidwell, W. R. Basement membrane collagen requirements for attachment and growth of mammary epithelium. Exp. Cell Res., 124, 181-190, 1979.
53. Elliott, J. T., Tona, A., Woodward, J. T., Jones, P. L. and Plant, A. L. Thin films of collagen affect smooth muscle morphology. Langmuir, 19, 1506-1514, 2003.
54. Macklis, J. D., Sidman, R. L. and Shine, H. D. Cross-linked collagen surface for cell culture that is stable, uniform, and optically superior to conventional surfaces. In vitro, 21, 189-194, 1985.
55. Spurlin, T. A., Bhadriraju, K., Chung, K.-H., Tona, A. and Plant, A. L. The treatment of collagen fibrils by tissue transglutaminase to promote vascular smooth muscle cell contractile signaling. Biomaterials, 30, 5486-5496, 2009.
56. Rehfeld, F., Engler, A. J., Eckhardt, A., Ahmed, F. and Discher, D. E. Cell responses to the mechanochemical microenvironment-implications for regenerative medicine and drug delivery. Adv. Drug Delivery Rev., 59, 1329-1339, 2007.
57. Kleinman, H. K., McGoodwin, E. B., Rennard, S. I. and Martin, G. R. Preparation of collagen substrates for cell attachment: effect of collagen concentration and phosphate buffer. Anal. Biochem., 94, 308-312, 1979.
58. Jacquemart, I., Pamuła, E., De Cupere, V. M., Rouxhet, P. G. and Dupont-Gillain, C. C. Nanostructured collagen layers obtained by adsorption and drying. J. Coll. Interface Sci., 278, 63-70, 2004.
59. Lanfer, B., Freudenberg, U., Zimmermann, R., Stamov, D., Körber, V. and Werner, C. Aligned fibrillar collagen matrices obtained by shear flow deposition. Biomaterials, 29, 3888-3895, 2008.
60. Jiang, F., Hörber, H., Howard, H. and Müller, D. J. Assembly of collagen into microribbons: effects of pH and electrolytes. J. Struct. Biol., 148, 268-278, 2004.
61. Habermehl, J., Skopinska, J., Boccafoschi, F., Sionkowska, A., Kaczmarek, H., Laroche, G. and Mantovani, D. Preparation of ready-to-use, stockable and reconstituted collagen. Macromol. Biosci., 5, 821-828, 2005.
62. Elliott, J. T., Woodward, J. T., Umarji, A., Mei, Y. and Tona, A. The effect of surface chemistry on the formation of thin films of native fibrillar collagen. Biomaterials, 28, 576-585, 2007. Mechanical Cues for Cell Culture
63. Bathia, S. N., Balis, U. J., Yarmush, M. L. and Toner, M. Microfabrication of hepatocyte/fibroblast co-cultures. Role of homotypic cell interactions. Biotechnol. Prog., 14, 378-387, 1998.
64. Sherratt, M. J., Bax, D. V., Chaudhry, S. S., Hodson, N., Lu, J. R., Saravanapavan, P. and Kielty, C. M. Substrate chemistry influences the morphology and biological function of adsorbed extracellular matrix assemblies. Biomaterials, 26, 7192-7206, 2005.
65. Ehrmann, R. L. and Gey, G. O. The growth of cells on a transparent gel of reconstituted rat tail collagen. J. Natl. Cancer Inst., 16, 1375-1403, 1956.
66. Roy, R., Boskey, A. and Bonassar, L. J. Processing of type I collagen gels using nonenzymatic glycation. J. Biomed. Mater. Res., 93A, 843-851, 2009.
67. Wells-Knecht, M. C., Thorpe, S. R. and Baynes, J. W. pathways of formation of glycoxidation products during glycation of collagen. Biochemistry, 34, 15134-15141, 1995.
68. Wu, C.-C., Ding, S.-J., Wang, Y.-H., Tang, M.-J. and Chang, H.-C. Mechanical properties of collagen gels derived from rats of different ages. J. Biomater. Sci. Polym. Edn., 16, 1261-1275, 2005.
69. Taubenberger, A. V., Woodruff, M. A., Bai, H., Muller, D. J. and Hutmacher, D. W. The effect of unlocking RGD-motifs in collagen I on pre-osteoblast adhesion and differentiation. Biomaterials, 31, 2827-2835, 2010.
70. Dunn, J. C. Y., Tompkins, R. G. and Yarmush, M. L. Long-term in vitro function of adult hepatocytes in a collagen sandwich configuration. Biotechnol. Progr., 7, 237-245, 1991.
71. Roeder, B. A., Kokini, K., Sturgis, J. E., Robinson, J. P. and Voytik-Harbin, S. L. Tensile mechanical properties of three dimensional type I collagen extracellular matrices with varied microstructure. J. Biomech. Eng., 124, 214-222, 2002.
72. Byfield, F. J., Reen, R., Shentu, T.-P., Levitan, I. and Gooch, K. J. Endothelial actin and cell stiffness is modulated by substrate stiffness in 2D and 3D. J. Biomech., 42, 1114-1119, 2009.
73. He, W., Ma Z. W., Yong T., Teo, W. E. and Ramakrishna, S. Fabrication of collagen-coated biodegradable polymer nanofiber mesh and its potential for endothelial cells growth. Biomaterials, 26, 7606-7615, 2005.
74. Wang, Y.-L. and Pelham, R. J. Preparation of a flexible, porous polyacrylamide substrate for mechanical studies of cultured cells. Methods Enzymol., 298, 489-496, 1998. 895
75. Pelham, R. J. and Wang, Y.-L. Cell locomotion and focal adhesions are regulated by substrate flexibility. Proc. Natl. Acad. Sci. USA, 94, 13661-13665, 1997.
76. Harris, A. K., Wild, P. and Stopak, D. Silicone rubber substrata: a new wrinkle in the study of cell locomotion. Science, 208, 177-179, 1980.
77. Saha, K., Keung, A. J., Irwin, E. F., Li, Y., Little, L., Schaffer, D. V. and Healy, K. E. Substrate modulus directs neural stem cell behavior. Biophys. J., 95, 4426-4438, 2008.
78. Antia, M., Baneyx, G. and Kubow, K. E. Fibronectin in aging extracellular matrix fibrils is progressively unfolded by cells and elicits an enhanced rigidity response. Faraday Discuss., 139, 229-249, 2008.
79. Engler, A. J., Richert, L., Wong, J. Y., Picart, C. and Discher, D. E. Surface probe measurements of the elasticity of sectioned tissue, thin gels and polyelectrolyte multilayer films: Correlations between substrate stiffness and cell adhesion. Surf. Sci., 570, 142-154, 2004.
80. Chiu, D. T., Jeon, N. L., Huang, S., Kane, R. S., Wargo, C. J., Choi, I. S., Ingber, D. E. and Whitesides, G. M. Patterned deposition of cells and proteins onto surfaces by using three-dimensional microfluidic systems. Proc. Natl. Acad. Sci. USA, 97, 2408-2413, 2000.
81. Kapur, R., Calvert, J. M. and Rudolph, A. S. Electrical, chemical, an topological addressing of mammalian cells with microfabricated systems. J. Biomech. Eng. T. ASME, 121, 65-72, 1999.
82. Folch, A. and Toner, M. Microengineering of Cellular Interactions. Annu. Rev. Biomed. Eng., 2, 227-256, 2000.
83. Leclerc, E., Sakai, Y. and Fujii, T. Cell culture in 3-dimensional microfluidic structure of PDMS (polydimethylsiloxane). Biomed. Microdev., 5 109-114, 2003.
84. Brown, X. Q., Ookawa, K. and Wong, J. Y. Evaluation of polydimethylsiloxane scaffolds with physiologically-relevant elastic moduli: interplay of substrate mechanics and surface chemistry effects on vascular smooth muscle cell response. Biomaterials, 26, 3123-3129, 2005.
85. Evans, N. D., Minelli, C., Gentleman, E., LaPointe, V., Patankar, S. N., Kallivretaki, M., Chen, X., Roberts, C. J. and Stevens, M. M. Substrate stiffness affects early differentiation events in embryonic stem cells. Eur. Cells Matter, 18, 1-14, 2009.
86. Eddington, D. T., Crone, W. C. and Beebe, D. J. Development of process protocols to fine tune polydimethylsiloxane material properties. 7th International conference on miniaturized chemical and biochemical analysis systems (Squaw Valley, California, USA), 2003. Mechanical Cues for Cell Culture
87. Harris, A. K., Stopak, D. and Wild, P. Fibroblast traction as a mechanism for collagen morphogenisis. Nature, 290, 249-251 1981.
88. Tan, J. L., Tien, J., Pirone, D. M., Gray, D. S., Bhadriraju, K. and Chen, C. S. Cells lying on a bed of microneedles: an approach to isolate mechanical force. Proc. Natl. Acad. Sci. USA, 100, 1484-1489, 2003.
89. Benya, P. D. and Shaffer, J. D. Dedifferentiated chondrocytes reexpress the differentiated collagen phenotype when cultured in agarose gels. Cell, 30, 215-224, 1982.
90. Engler, A., Bacakova, L., Newman, C., Hategan, A., Griffin, M. and Discher, D. Substrate compliance versus ligand density in cell on gel responses. Biophys. J., 86, 617-628, 2004.
91. Wang, H.-B., Dembo, M. and Wang Y.-L. Substrate flexibility regulates growth and apopotosis of normal but not transformed cells. Am. J. Physiol. Cell Physiol., 279, 1345-1350, 2000.
92. Georges, P. C., Miller, W. J., Meaney, D. F., Sawyer, E. S. and Janmey, P. A. Matrices with compliance comparable to that of brain tissue select neuronal over glial growth in mixed cortical cultures. Biophys. J., 90, 3012-3018, 2006.
93. Yeung, T., Georges, P. C., Flanagan, L. A., Marg, B., Ortiz, M., Funaki, M., Zahir, N., Ming, W., Weaver, V. and Janmey, P. A. Effects of substrate stiffness on cell morphology, cytoskeletal structure, and adhesion. Cell Motil. Cytoskel., 60, 24-34, 2005.
94. Solon, J., Levental, I., Sengupta, K., Georges, P. C. and Janmey, P. A. Fibroblast adaptation and stiffness matching to soft elastic substrates. Biophys. J., 93, 4453-4461, 2007.
95. Peyton, S. R. and Putnam A. J. Extracellular matrix rigidity governs smooth muscle cell motility in a biphasic fashion. J. Cell Physiol., 204, 198-209, 2005.
96. Jiang, G., Huang, A. H., Cai, Y., Tanase, M. and Sheetz, M. P. Rigidity sensing at the leading edge through avv3 integrins and RPTPi. Biophys. J., 90, 1804-1809, 2006.
97. Reinhart-King, C. A., Dembo, M. and Hammer, D. A. Cell-cell mechanical communication through compliant substrates. Biophys. J., 95, 6044-6051, 2008.
98. Balgude, A. P., Yu, X., Szymanski, A. and Bellamkonda, R. V. Agarose gel stiffness determines rate of DRG neurite extension in 3D cultures. Biomaterials, 22, 1077-1084, 2001.
99. Semler, E. J. and Moghe, P. V. Engineering hepatocyte functional fate through growth factor dynamics. The role of cell morphologic priming. 897 Biotech. Bioeng., 75, 511-520, 2001; G' values are reported in Semler, E. J, Ranucci, C. S., Moghe P. V. Mechanochemical manipulation of hepatocyte aggregation can selectively induce or repress liver-specific function. Biotech. Bioeng., 69, 359-369, 2000.
100. Gaça, M. D. A., Zhou, X., Issa, R., Kiriella, K., Iredale, J. P. and Benyon, R. C. Basement membrane-like matrix inhibits proliferation and collagen synthesis by activated rat hepatic stellate cells. Evidence for matrixdependent deactivation of stellate cells. Matrix Biol., 22, 229-239, 2003.
101. Saez, A., Buguin, A., Silberzan, P. and Ladoux, B. Is the mechanical activity of epithelial cells controlled by deformations or forces? Biophys. J.: Biophys. Lett., 89, L52-L54, 2005.
102. Sieminski, A. L., Hebbel, R. P. and Gooch, K. J. The relative magnitudes of endothelial force generation and matrix stiffness modulate capillary morphogenesis in vitro. Exp. Cell Res., 297, 574-584, 2004.