Microfabrication of hepatocyte/fibroblast co-cultures: Role of homotypic cell interactions

Biotechnology Progress

Volumn 14, Issue 3, 1998, Pages 378-387

  Bhatia, S N ^a   Balis, U J ^a   Yarmush, M L ^a   Toner, M ^a,b  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b Shriners Burns Research Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL INTERACTION; CELL MATURATION; CULTURE TECHNIQUE; EMBRYO DEVELOPMENT; FIBROBLAST; HOMOTYPIC CELL INTERACTION; LIVER CELL; MICROFABRICATION; MURINE; PATHOPHYSIOLOGY;

BIOLOGICAL MATERIALS; BIOMARKERS; BIOTECHNOLOGY; CELLS; GROWTH KINETICS; INTERFACES (MATERIALS); MATHEMATICAL MODELS; METABOLISM;

FIBROBLAST CO CULTURE; HEMOTYPIC CELL INTERACTIONS; HEPATOCYTES; MICROFABRICATION TECHNIQUES;

TISSUE CULTURE;

3T3 CELLS; ANIMALS; CELL COMMUNICATION; COCULTURE TECHNIQUES; FEMALE; FIBROBLASTS; LIVER; MICE; RATS; RATS, INBRED LEW;

MURINAE;

EID: 0032077407     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp980036j     Document Type: Article

References (49)

1. Aufderheide, E.; Chiquet-Ehrismann, R.; Ekblom, P. Epithelial-mesenchymal interactions in the developing kindey lead to expression of terascin in the mesenchyme J. Cell Biol. 1987, 105,599-608.
2. Ben-Ze'ev, A.; Robinson, G. S.; Bucher, N. L.; Farmer, S. R. Cell-cell and cell-matrx interactions differentially regulate the expression of hepatic and cytoskeletal genes in primary cultures of rat hepatocytes Proc. Natl. Acad. Sci. U.S.A. 1988, 55, 2161-2165.
3. Bergsteinsdottir, K.; Kingston, A.; Mirsky, R.; Jessen, K. R. Rat schwann cells produce mterleukin-1. J. Neuroimmunol. 1991, 34,15-23.
4. Bhatia, S. N.; Yarmush, M. L.; Toner, M. Controlling homotypic vs heterbtypic interactions by micropatterning; co-cultures of hepatocytes and 3T3 fibroblasts J. Biomed. Mater. Res. 1997, 34 (2), 189-199.
5. Bhatia, S. N.; Balis, U. J.; Yarmush, M. L.; Toner, M. Engineering Tissue Function Through Microscale Control of Cell-Cell Interactions 1998a, submitted.
6. Bhatia, S. N.; Balis, U. J.; Yarmush, M. L.; Toner, M. Probing Heterotypic Cell Interactions: Hepatocyte Function in Microfabricated Co-Cultures. J. Biomater. Sci. 1998b, in press.
7. Bissell, D. M.; Arenson, D. M.; Maher, J. J.; Roll, F. J. Support of cultured hepatocytes by a laminin-rich gel: Evidence for a functionally significant subendothelial matrix in normal rat liver. J. Clin. Invest. 1987, 79, 801-812.
8. Bousse, L.; Mcreynolds, R. J.; Kirk, G.; Dawes, T.; Lam, P.; Bemiss, W. R.; Farce, J. W. Micromachined multichannel systems for the measurement of cellular-metabolism. Sens. Actuators, B 1994, 20 (2-3), 145-150.
9. Britland, S.; Perez-Arnaud, E.; Clark, P.; McGinn, B.; Connolly, P.; Moores, G. Micropatterning proteins and synthetic peptides on solid supports: a novel application for microelectronics fabrication technology. Biotechnol. Prog. 1992, 8,155-160.
10. Chen, C. S.; et al. Geometric Control of Cell Life and Death. Science 1997, 276, 1425-1428.
11. Clark, P.; Britland, S.; Connolly, P. Growth cone guidance and neuron morphology on micropatterned laminin. J. Cell Sci. 1993, 105, 203-212.
12. Donate, M. T.; Gómez-Lechón, M.J.; Castell, J. V. Drug metabolizing enzymes in rat hepatocytes co-cultured with cell lines. In Vitro Cell Dev. Biol. 26, 1990, 1057-1062.
13. Donato, M. T.; Castell, J. V.; Gomez-Lechon, M. J. Cytochrome P450 activities in pure and co-cultured rat hepatocytes: effects of model inducers In Vitro Cell Dev. Biol. 30A (12), 1994, 825-832.
14. Dunn, J. C. Y.; Yarmush, M. L.; Koebe, H. G.; Tompkins, R. G. Hepatocyte function and extracellular matrix geometry: Long-term culture in a sandwich configuration FASEB J. 1989, 3,174-177.
15. Dunn, J. C. Y.; Tompkins, R. G.; Yarmush, M. L. Long-term in vitro function of adult hepatocytes in a collagen sandwich configuration. Biotechnol. Prog. 1991, 7, 237-245.
16. Dunn, J. C. Y.; Tompkins, R. G.; Yarmush, M. L. Hepatocytes in collagen sandwich: evidence for transcriptional and translational protein. J. Cell Biol. 116 (4), 1992, 1043-1053.
17. Fillinger, M. F.; O'Connor, S. E.; Wagner, R. J.; Cronenvett, J. L. The effect of endothelial cell coculture on smooth muscle cell proliferation. J. Vasc. Surg. 1993, 17, 1058-1067.
18. Fini, M. E.; Strissel, K. J.; Girard, M. T.; Mays, J. W.; Rinehart, W. B. Interleukin 1 alpha mediates collagenase synthesis. J. Biol. Chem. 1994, 269, 11291-11298.
19. Gerard, N.; Corlu, A.; Kneip, B.; Kercret, H.; Rissel, M.; Guguen-Guillouzo, C.; Jegou, B. Liver-regulating protein is a plasma membrane protein involved in cell contact-mediated regulation of Sertoli eel function by primary spermatocytes. J. Cell Sei. 1995, 108, 917-925.
20. Guguen-Guillouzo, C.; Clement, B.; Baffet, G.; Beaumont, C.; Morel-Chany, E.; Glaise, D.; Guillouzo, A. Maintenance and reversibility of active albumin secretion by adult rat hepatocytes co-cultured with another liver epithelial cell type. Exp. Cell Res. 1983, 143,47-64.
21. Hammarback, J. A.; McCarthy, J. B.; Palm, S. L.; Furcht, L. T.; Letourneau, P. C. Growth cone guidance by substratebound laminin pathways is correlated with neuron-to-pathway adhesivity. Dev. Biol. 1988, 126, 29-39.
22. Houssaint, E. Differentiation of the mouse hepatic primbrdium.I. an analysis of tissue interactions in hepatocyte differentiation. Cell Differ. 1990, 9, 269-279.
23. Howlett, A. R.; Hodges, G. M.; Rowlatt, C. Epithelial-stromal interactions in the adult bladder: urothelial growth, differentiation, and maturation on culture facsimiles of bladder stroma. Dev. Biol. 1986, 118, 403-415.
24. Ichihara, A. Mechanisms controlling growth of hepatocytes in primary culture. Dig. Dis. Sci. 1991, 36 (4),489-493.
25. Koide, N.; Sakguchi, K.; Koide, Y.; Asano, K.; Kawaguchi, M.; Matsushima, H.; Takenami, T.; Shinji, T.; Mor, M.; Tsuji, T. Formation of multicellular spheroids composed of adult rat hepatocyes in dishes with positively charged surfaces and under other nonadherent environments Exp. Cell Res. 1990, 186,227-235.
26. Kuri-Harcuch, W.; Mendoza-Figueroa, T. Cultivation of adult rat hepatocytes on 3T3 cells: expression of various liver differentiated functions. Differentiation, 1989, 41,148-157.
27. Lom, B.; Healy, K. E.; Hockberger, P. E. A versatile technique for patterning biomolecules onto glass coverslips. J. Neurosci. Methods 1993, 50, 385-397.
28. Macdonald, C.; Pitt, A. M. Rapid DNA Quantitation Using Hoecsht 33258 Dye in a Multiwell Fluorescent Plate Reader J. Cell Biol. 1991, 115, 79a.
29. Matsuo, R.; Ukida, M.; Nishikawa, Y.; Omori, N.; Tsuji, T. The role of Kupffer cells in complement in D-galactosamine/ lipopolysaccharide-induced hepatic injury of rats. Acta Med. Okayama 1992, 46, (5),345-354.
30. Mesnil, M.; Fraslin, J.; Piccoli, C.; Yamasaki, H.; Guguen-Guillouzo, C. Cell contact but not junctional communication (dye coupling) with biliary epithelial cells is required for hepatocytes to maintain differentiated functions. Exp. Cell Res. 1987, 173, 524-533.
31. Moghe, P. V.; Coger, R. N.; Toner, M.; Yarmush, M. L. Cell-cell interactions are essential for maintenance of hepatocyte function in collagen gel but not on matrigel. Biotechnol. Bioeng. 1997, 56 (6), 707.
32. Morin, O., Goulet, F., Normand, C.; Eds. Liver sinusoidal endothelial cells: isolation, purification, characterrization and interaction with hepatocytes; Springer International: New York, 1988.
33. Naughton, B. A. The importance of stromal cells. In Biomedical Engineering Handbook; Bronzino, J. D. Ed.; CRC Press: Boca Raton, FL, 1995.
34. Nishida, M.; Sprinhorn, J. P.; Kelly, R. A.; Smith, T. W. Cell-cell signaling between adult rat ventricular myocytes and cardiac microvascular endothelial cells in heterotypic primary culture. J. Clin. Invest. 1993, 91, 1934-1941.
35. Rheinwald, J. G.; Green, H. Serial Cultivation of Strains of Human Epidermal Keratinocytes: the Formation of Keratinizing Colonies from single cells. Cell 1975, 6,331-343.
36. Rincon-Sanchez, A. R.; Hernandez, A.; Lopez, M. L.; Mendoz-Figueroa, T. Synthesis and secretion of lipids by long-term cultures of female rat hepatocytes. Biol. Cell. 1992,131-138.
37. Rojkind, M.; Novikoff, P. M.; Greenwel, P.; Rubin, J.; Rojas-Valencia, L.; de Carvalho, A. C.; Stockert, R.; Spray, D.; Hertzberg, E. L.; Wolkof, A. W. Characterization and functional studies on rat liver fat-storing cell line and freshly isolated hepatocyte coculture system. Am. J. Pathol. 1995, 146 (6), 1508-1520.
38. Rozga, J.; Morsiani, E.; LePage, E.; Moscioni, A. D.; Giorgio, T.; Demetriou, A. A. Isolated hepatocytes in a bioartificial liver: a single group view and experience. Biotechnol. Bioeng. 1994, 43, 645-653.
39. Ruch, R. J.; Guan, X.; Sigler, K. Inhibition of Gap Junctional Intercellular Communication and Enhancement of Growth in BALB/c 3T3 Cells Treated With Connexin43 Antisense Oligonucleotides Mol. Carcinog. 1995, 14, 269-274.
40. Seglen, P. O. Preparation of isolated rat liver cells. Methods Biol. 1976, 13,29-83.
41. Shimaoka, S.; Nakamura, T.; Ichihara, A. Stimulation of growth of primary cultured adult rat hepatocytes without growth factors by coculture with nonparenchymal liver cells Exp. Cell Res. 1987, 172,228-242.
42. Simon-Assmann, P.; Bouziges, F.; Arnold, C.; Haffen, K.; Kedinger, M. Epithelial mesenchymal interactions in the production of basement membrane components in the gut. Development 1988, 102, 339.
43. Slavkin, H. C.; Snead, M. L.; Zeichner-David, M.; Jaskoll, T. F.; Smith, B. T. Concepts of epithelial-mesenchymal interactions during development: tooth and lung organogenesis. J. Cell Biochem. 1984, 26, 117-125.
44. Sporn, M. B.; Roberts, A. B. The transforming growth factor-betas In Peptide Growth Factors and Their Receptors I; Sporn, M. B., Roberts, A. B., Eds.; Springer-Verlag: New York, 1990.
45. Sussman, N. L.; Chong, M. G.; Koussayer, T.; He, D. E.; Shang, T. A.; Whisennand, H. H.; Kelly, J. H. Reversal of fulminant hepatic failure using an extrcorporeal liver assist device. Hepatology 1992, 16, 60-65.
46. Turner, S.; Kam, L.; Isaacson, M.; Craighead, H. G. Shain, W.; Turner, J. Cell attachment on silicon nanostructures. J. Vasc. Sci. Technol., B 1997, 15 (6), 2848-2854.
47. Utesch, D.; Molitor, E.; Platt, K. L.; Oesch, F. Differential stabilization of cytochrpme p-450 isoenzymes in primary cultures of adult rat liver parenchymal cells. In Vitro Cell Dev. Biol. 1991, 27A, 858-863.
48. Wu, F.; Peshwa, M.; Cerra, F.; Hu, W. Entrapment of hepatoctye spheroids in a hollow fiber bioreactor as a potential bioartificial liver. Tissue Eng. 1995, 1 (1),29-40.
49. Zsebo, K. M.; et al. Stem Cell Factor is encoded at the S1 locus of the mouse and is the ligand for the c-kit tyrosine kinase receptor. Cell 1990, 63, 213-224.