Reactive oxygen species contribute to neuropathic pain and locomotor dysfunction via activation of CamKII in remote segments following spinal cord contusion injury in rats

Pain

Volumn 154, Issue 9, 2013, Pages 1699-1708

  Gwak, Young S ^a   Hassler, Shayne E ^a   Hulsebosch, Claire E ^a  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

Author keywords

Below level central neuropathic pain; CamKII; Hyperexcitability; Reactive oxygen species; Spinal cord injury

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; N TERT BUTYL ALPHA PHENYLNITRONE; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CONTUSION; DOSE RESPONSE; ELECTROPHYSIOLOGY; ENVIRONMENTAL CHANGE; EXCITABILITY; IMMUNOHISTOCHEMISTRY; INTRACELLULAR SIGNALING; LAMINECTOMY; LOCOMOTION; MALE; NERVE CELL; NEUROPATHIC PAIN; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPINAL CORD DORSAL HORN; SPINAL CORD INJURY; SYNAPTIC TRANSMISSION;

BELOW-LEVEL CENTRAL NEUROPATHIC PAIN; CAMKII; HYPEREXCITABILITY; REACTIVE OXYGEN SPECIES; SPINAL CORD INJURY;

ANALYSIS OF VARIANCE; ANIMALS; ANTIGENS, CD11B; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; DISEASE MODELS, ANIMAL; EVOKED POTENTIALS; GAIT DISORDERS, NEUROLOGIC; GENE EXPRESSION REGULATION; HYPERALGESIA; MALE; NERVE TISSUE PROTEINS; NEURALGIA; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SPINAL CORD; SPINAL CORD INJURIES;

EID: 84881665549     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1016/j.pain.2013.05.018     Document Type: Article

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