Sustained CaMKII activity mediates transient oxidative stress-induced long-term facilitation of L-type Ca 2+ current in cardiomyocytes

Free Radical Biology and Medicine

Volumn 51, Issue 9, 2011, Pages 1708-1716

  Song, Young Hwan ^a   Choi, Euna ^b   Park, Sun Hyun ^b   Lee, Suk Ho ^b   Cho, Hana ^c   Ho, Won Kyung ^b   Ryu, Shin Young ^b  

^a Inje University College of Medicine   (South Korea)

^b Seoul National University   (South Korea)

^c Sungkyunkwan University   (South Korea)

Author keywords

Autophosphorylation; CaMKII; Free radicals; L type Ca 2+ current; Mitochondrial ROS generation; Oxidation; Oxidative stress

Indexed keywords

CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM CHANNEL L TYPE; CALCIUM ION; HYDROGEN PEROXIDE; N [2 [[N [3 (4 CHLOROPHENYL) 2 PROPENYL] N METHYLAMINO]METHYL]PHENYL] N (2 HYDROXYETHYL) 4 METHOXYBENZENESULFONAMIDE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; AUTOPHOSPHORYLATION; CALCIUM CURRENT; CALCIUM TRANSPORT; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HEART ARRHYTHMIA; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; LONG TERM FACILITATION; MALE; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PATHOPHYSIOLOGY; PRIORITY JOURNAL; RAT; SARCOPLASMIC RETICULUM;

ANIMALS; BENZYLAMINES; CALCIUM; CALCIUM CHANNELS, L-TYPE; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; HYDROGEN PEROXIDE; MALE; MITOCHONDRIA; MYOCYTES, CARDIAC; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SULFONAMIDES;

RATTUS;

EID: 80053604110     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.07.022     Document Type: Article

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