Optimal time and dosage of phenyl N-tert-butyl nitrone (PBN) for the inhibition of nitric oxide synthase induction in mice

Free Radical Biology and Medicine

Volumn 22, Issue 3, 1997, Pages 463-470

  Miyajima, Takashi ^a   Kotake, Yashige ^a  

^a OKLAHOMA MEDICAL RESEARCH FOUNDATION   (United States)

Author keywords

EPR; Free radicals; iNOS; Nitric oxide; NO synthase; PBN; RT PCR; Spin trapping

Indexed keywords

ESCHERICHIA COLI LIPOPOLYSACCHARIDE; FREE RADICAL; N TERT BUTYL ALPHA PHENYLNITRONE; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE INHIBITOR;

ANIMAL MODEL; ARTICLE; DOSE TIME EFFECT RELATION; ENDOTOXEMIA; ENZYME INHIBITION; GENE EXPRESSION; MOUSE; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEPTIC SHOCK;

ANIMALS; BLOTTING, NORTHERN; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRON SPIN RESONANCE SPECTROSCOPY; ENDOTOXINS; ENZYME INDUCTION; ENZYME INHIBITORS; LIVER; MALE; MICE; MICE, INBRED BALB C; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITROGEN OXIDES; RNA, MESSENGER; SPIN LABELS;

EID: 0031032290     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(96)00391-7     Document Type: Article

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