Ginsenoside Rd Attenuates Myocardial Ischemia/Reperfusion Injury via Akt/GSK-3β Signaling and Inhibition of the Mitochondria-Dependent Apoptotic Pathway

PLoS ONE

Volumn 8, Issue 8, 2013, Pages

  Wang, Yang ^a   Li, Xu ^a   Wang, Xiaoliang ^b   Lau, Waynebond ^b   Wang, Yajing ^b   Xing, Yuan ^a   Zhang, Xing ^a   Ma, Xinliang ^b   Gao, Feng ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE 3; CASPASE 9; CREATINE KINASE; CYTOCHROME C; GINSENOSIDE RD; GLYCOGEN SYNTHASE KINASE 3BETA; LACTATE DEHYDROGENASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN BAX; PROTEIN BCL 2; PROTEIN KINASE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; DRUG STRUCTURE; FLOW CYTOMETRY; HEART FUNCTION; HEART INFARCTION SIZE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART PROTECTION; IN VITRO STUDY; IN VIVO STUDY; MALE; MITOCHONDRIAL MEMBRANE POTENTIAL; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REPERFUSION INJURY; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; APOPTOSIS; BENZIMIDAZOLES; CARBOCYANINES; CARDIOTONIC AGENTS; CASPASES; CYTOCHROMES C; FLUORESCENT DYES; GENE EXPRESSION REGULATION; GINSENOSIDES; GLYCOGEN SYNTHASE KINASE 3; L-LACTATE DEHYDROGENASE; MALE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; MYOCYTES, CARDIAC; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84881578443     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0070956     Document Type: Article

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